GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS HUMIGJBL2 194 bp ss-mRNA PRI 18-MAY-1991
DEFINITION Human Burkitt's lymphoma JBL2 mRNA for mu-immunoglobulin heavy
chain with truncated VH region
ACCESSION X52895 X13872
KEYWORDS constant region; immunoglobulin; immunoglobulin heavy chain;
mu-immunoglobulin; rearranged DNA; variable region.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 194)
AUTHORS Cogne,M., Mounir,S., Preud'homme,J.L., Nau,F. and Guglielmi,P.
TITLE Burkitt's lymphoma cell lines producing truncated mu immunoglobulin
heavy chains lacking part of the variable region
JOURNAL Eur. J. Immunol. 18, 1485-1489 (1988)
STANDARD full automatic
REFERENCE 2 (bases 1 to 194; 1 to 194)
AUTHORS Cogne,M.C.
JOURNAL Unpublished (1990)
STANDARD full automatic
COMMENT *source: cell line=BL JBL2; cell type=B cell.
From EMBL 26 entry HSIGJBL2; dated 25-FEB-1991.
FEATURES Location/Qualifiers
CDS 22..>194
/note="JBL2 Ig mu heavy chain precursor (194 is 2nd base
in codon)"
/codon_start=22
CDS 22..78
/note="signal peptide (AA -19 to -1)"
/codon_start=22
misc_feature 67..145
/note="VH exon derived region"
CDS 79..>194
/note="mat. JBL2 Ig mu heavy chain (AA 1-58) (194 is 2nd
base in codon)"
/codon_start=79
misc_feature 123..124
/note="deletion site (3 codons, AA 16-18)"
misc_feature 146..194
/note="mu CH1 exon 5' end derived region"
BASE COUNT 31 a 66 c 51 g 46 t
ORIGIN
1 caggatctca cgtgcaagaa aatgaagcac ctgtggttct tcctcctgct ggtggcggct
61 cccagatggg tcctgtccca gttgcagttg ccggagtcgg gcccaggact cgtgagaccc
121 ccagccctca tctgtactgg ctctgggagt gcatccgccc caaccctttt ccccctcgtc
181 tcctgtgaga attc
//