GenBank-Updates@genbank.bio.net (05/19/91)
LOCUS HUMIGLY91 260 bp ss-mRNA PRI 19-MAY-1991
DEFINITION Human Burkitt's lymphoma Ly91 mRNA for mu-immunoglobulin heavy
chain with truncated VH region
ACCESSION X52894 X13872
KEYWORDS immunoglobulin; immunoglobulin heavy chain; mu-immunoglobulin;
rearranged DNA; variable region.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 260)
AUTHORS Cogne,M., Mounir,S., Preud'homme,J.L., Nau,F. and Guglielmi,P.
TITLE Burkitt's lymphoma cell lines producing truncated mu immunoglobulin
heavy chains lacking part of the variable region
JOURNAL Eur. J. Immunol. 18, 1485-1489 (1988)
STANDARD full automatic
REFERENCE 2 (bases 1 to 260; 1 to 260)
AUTHORS Cogne,M.C.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 3 (bases 1 to 260)
AUTHORS Sparkowski,J.J. and Das,A.K.
TITLE The nucleotide sequence of greA, a suppressor gene that restores
growth of an Escherichia coli RNA polymerase mutant at high
temperature
JOURNAL Nucleic Acids Res. 18, 6443-6443 (1990)
STANDARD full automatic
COMMENT *source: cell line=BL Ly91; cell type=B cell.
From EMBL 26 entry HSIGLY91; dated 25-FEB-1991.
FEATURES Location/Qualifiers
CDS 55..>260
/note="Ly91 Ig mu heavy chain precursor (260 is 2nd base
in codon)"
/codon_start=55
CDS 55..111
/note="signal peptide (AA -19 to -1)"
/codon_start=55
misc_feature 101..211
/note="VH exon derived region"
CDS 112..>260
/note="mat. Ly91 Ig mu heavy chain (AA 1-50) (260 is 2nd
base in codon)"
/codon_start=112
misc_feature 154..156
/note="additional +14a codon"
misc_feature 212..260
/note="mu CH1 exon 5' end derived region"
BASE COUNT 52 a 71 c 66 g 71 t
ORIGIN
1 cctgttccca ggagtttcca cttggtgatc agcactgaac acagaccacc aaccatggac
61 tttgggctta gctgggtttt ccttgttggt attttaaaag gtatgcaatg tgaggtgcaa
121 ctggtggaat ctgggggagg ctcgatacag ccaccagggc ggtcccagag accctcctat
181 acatgttctg gttccacttc tggtgatcat gggagtgcat ccgccccaac ccttttcccc
241 ctcgtctcct gtgagaattc
//