GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS RATIID4G 9448 bp ds-DNA ROD 18-MAY-1991
DEFINITION Rat P450 IID4 gene.
ACCESSION X52029 X52457
KEYWORDS Cytochrome P450; cytochrome; cytochrome P450 IID4.
SOURCE Rattus sp. DNA.
ORGANISM Rattus sp.
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 9448)
AUTHORS Matsunaga,E., Umeno,M. and Gonzalez,F.J.
TITLE The rat P450 IID subfamily: complete sequences of four closely
linked genes and evidence that gene conversions maintained sequence
homogeneity at the heme-binding region of the cytochrome P450
active site.
JOURNAL J. Mol. Evol. 30, 155-169 (1990)
STANDARD full automatic
COMMENT From EMBL entry RSIID4G; dated 21-FEB-1991.
FEATURES Location/Qualifiers
mat_peptide join(:1331..1519,:2953..3124,:3350..3502,:3583..3743,
:4123..4299,:4483..4624,:4846..5033,:5466..5607,
:5708..5883)
/product="cytochrome P450 IID3 protein"
/gene="P450 IID4"
mRNA join(:<1331..1519,:2953..3124,:3350..3502,:3583..3743,
:4123..4299,:4483..4624,:4846..5033,:5466..5607,
:5708..>5886)
/gene="P450 IID4"
exon <1331..1519
CDS join(:1331..1519,:2953..3124,:3350..3502,:3583..3743,
:4123..4299,:4483..4624,:4846..5033,:5466..5607,
:5708..5886)
/product="cytochrome P450 IID3 protein"
/gene="P450 IID4"
/codon_start=1331
TATA_signal 1245..1247
prim_transcript 1277..>6034
/gene="P450 IID4"
intron 1520..2952
/number=1
exon 2953..3124
intron 3125..3349
/number=2
/cons_splice=(5'site:no,3'site:yes)
/note="gc instead of gt"
exon 3350..3502
intron 3503..3582
/number=3
exon 3583..3743
intron 3744..4122
/number=4
exon 4123..4299
intron 4300..4482
/number=5
exon 4483..4624
intron 4625..4845
/number=6
exon 4846..5033
intron 5034..5465
/number=7
exon 5466..5607
intron 5608..5707
/number=8
exon 5708..>5886
polyA_signal 5936..5941
polyA_site 6034..6034
BASE COUNT 2337 a 2420 c 2465 g 2226 t
ORIGIN
1 gaattctgat ctgttaatat ttggggggat tgagcacaac agcatcgtca tttggggggc
61 acaaatgatg atttttttgc tgtgtatgtg tgctctgtag ctacttatca tccagggaca
121 gacatggttc tcccagctaa gaaagcagcc agagttgcta agtgacttcc tcaaaattgc
181 caaataatgc agctgtctgg aaatgagaaa ggaggtgggg cagaatgggg ggagggagct
241 tgatctcccc cctcgccccc cccccccggc gatgtgattt ccactcagca acgttgattg
301 taactcaaca agggaatgct ttttcctgtt tgggcctttg cccacaaaca aaggcgtttt
361 cataatatgc cgatggaatg tatcttggtt gcagacagcc gtagtctggc ttagaggcgg
421 tgaagctttt aggttagagt gtgtaagaag ctaatgctaa acttgctgac tctcggactt
481 gtgcggatgg ctcagagagc tagggtcttc attctagtgg acctggagtg gacagaggtc
541 tgtctgggtc actaggaaaa gcctagtttc ttctctttaa attttgatga ttgaatgagc
601 gagaggcctg ggagccttct gcagcgagtg caatcgctag catttgccaa ctgctcgcag
661 tggaagggta cgagacgcat ctgagctggc ttttggccat cctgtttgat gagaagtgtg
721 tgacaaagta aaatagggcc tgtgggagtg ggagacacca cataggagcc aagccaaact
781 ctgaagattg tctgatggct cagttcatat tacctgtact ccttgattct gtggagaacc
841 ttcctctaga taaggtcaca gacatccaag cgtcgactct cctgctgggg gcgggggagg
901 gggggagtca aacccttaat tatggctttc taattcccta cgccatcagt ggctattgcc
961 ctgggcctac aattttctgc cattcctctt gaaaagatgt tgctcttggg gagatgcaac
1021 acacaaacac acacacacac acacacacac acacacacac atacacacaa gcaagcatgc
1081 acacacgcat gcacaaacag aacttagaga aggagggatc tctaagacca aatgcccctg
1141 gcctgccttg aaccttcctt gcactctgca tggtcagtgc agccacttgg cttaaggcag
1201 aggagaaagg gcagctcggt cccttattga gtgcccaggg cctgataatg ctatcgttcc
1261 ttggtcctag gtggctgtag tcgggattga gaggtgtttc caaagaaacc caaagagcag
1321 cagggcagcc atgaggatgc cgacggggtc tgaactgtgg cccatagcca tattcacgat
1381 catcttcctg cttctggtgg acctgatgca caggcgccag cgctggactt ctcgctaccc
1441 tccgggccct gtgccctggc ctgtgctggg caacctgctg cagatagact tccagaatat
1501 gccagcgggc tttcaaaagg taagggaatt gttggtgggc aggagaggcc atggtgaccc
1561 cttattagaa caagtgagtg gtggtgaaac tgcatgctgg acacggagct ggtccccagg
1621 acaaagcggg ttaagaggct tctcctgggg ctggggattt agctcagtgg tagagcgctt
1681 acctaggaag cgcaaggccc tgggttcggt ccccagctcc gaaaaaaaga accaaaaaaa
1741 aaaaaaaaaa aaagaggctc ctcctgaaga gggtggtgca gaacccgaag actcactgga
1801 gtttccaaag gcaacagcta ggaggtgaga tgggtcctgg cagccgtctg agatccagtt
1861 aacaggatag gctgtaaggg ttggtggtga tgctggggtt gcattctgat cccagagcac
1921 ctgtagttgg gaggctaaag caggtaggtt atgaattcca tcttgaactg catagcgaaa
1981 ctctctctaa aatggagact taaaggccag ctgtggaggt gctcgcctct aagcccagcg
2041 cttaagagac agaggtgggc atatttcttt gagtcctagg ctagtctggt ctaacatact
2101 gagttccagg cccatgctac atagtgaaac tgtttccaaa agaaatctaa cattttaaaa
2161 ggaaaaaaac aatcaatgca gtggtggaga ctttcacagc attcacagga ggcaaaagcc
2221 agcagatctc tgtgaattca gcaccagctt gacctacata gaaagtccca agccgaccct
2281 agctacatac taagacaaaa attacacaca cacacacaca cacacacaca cacactgaat
2341 gaatgaatga atgaatgaat gaatggaaaa tcgagtcatc gagtcatata ggcttcatat
2401 tccttttcat tccactggag ggaaatgttt caagaatgca ggaaggggca ctggagggtg
2461 gctcagtggt taagagcact gactgctctt ccagaggtcc tgagttcaat tcccagcaac
2521 cacatggtgg ctataaccat ctataatggg atcaataccc tcttctggtt tgtctgaaga
2581 cagcaacaat ctattcatat acataaagtc ttttaaaaat ggggcggggc catgatccta
2641 aacgagtgtc tctgtcagga aatcaaagtt gagagacagg aagtgctgct cccatccttt
2701 tgctgtttcc gattctcagg ctcccctaca tctgtgaggc ttagtttcct catctagaca
2761 tggggatgcc agtgggacca accggcaaat gcgtgacacc agcaaggtcg gagtccaagg
2821 tggttcccca gacaaataat agatgtcatc cttctgtagg gctcgctctg ggtctccccg
2881 ccaagtcctg tctagtacag ctaagcgcgg taacccaggc ttgctggtaa caccctcact
2941 ccctgcctac agctgagatg tcgctttggg gacctgttca gcttacagct ggcctttgag
3001 tcggtggttg tactgaatgg gctgccagcc ctgcgagagg cactggtgaa atacagcgag
3061 gacaccgctg accggccacc gctgcatttc aatgaccagt cgggctttgg accacgctct
3121 caaggcaaat gcagacagtg gcaggagtgg tggggaaagg gagactagag agggctcggg
3181 gaccagaggc agtttgggac ctagttgagg tggaggaggg acaggaacgg agaaaagaca
3241 aggaaggcag acagctaacg ggtgagcaaa gggtctgaca gtggtggcag tgaagtagca
3301 taggggcagg aaagagggcg aggtctcagg cctaagtgtg gtactccagg tgtggtcctc
3361 gcgaggtatg gacctgcctg gcgtcagcag cggcgcttct ctgtgtccac cttccgtcac
3421 tttggcctgg gcaagaagtc actggagcag tgggtgacag aggaggccag atgcctctgt
3481 gctgccttcg ctgaccatag tggtaggtgg tggattggtg gggataggtg gggataggtg
3541 gggagagaca accaaggtcc tgactggcat ttctgctccc aggattccct ttcagcccta
3601 acactctact ggacaaagca gtgtgtaacg tgatcgcgtc cctcctcttt gcctgccgct
3661 ttgaatacaa tgacccacgc ttcatcaggc tcctggactt gctgaaggac actcttgagg
3721 aggaatctgg attcctgccc atggtacgag ggttggggtt ctctgtaccc agatgacttc
3781 agacagtgga gtctctcagg gagatgattg acatgcagga gtgacaggag gaggacattc
3841 tgggaggaga tggatacacg tcaatgggaa ggacggggta ggctagaagt gcctagaaat
3901 agtgagtgcc tgggctcctc atccatgtgg cagccacaca ggtctgtgac atttccacag
3961 tatgatgacc cttctggaag ctcagggcaa agaggaaagt cagaggctgg cagggaggga
4021 cgatgtcacc tgtctatcct ggaggacact gggaccaggg gctattgcaa gtgagcccgg
4081 ggccccctgg cctctccatt ggtccctctg tgctgcccac agctcctgaa tgtgttcccg
4141 atgctcctac acatcccagg gcttcttggc aaggtattct ctggaaagaa ggccttcgtt
4201 gccatgctgg acgagctgct aactgaacac aaggtgacct gggaccctgc gcagccaccc
4261 cgagatctga ctgatgcctt cctggctgag gtggagaagg tgattggcag ctccaagaga
4321 tgtagccgga agctatgggc tgaggtcctg tgagctgtga ggccagatgg gtagggtcct
4381 gtgtatcacc aagtgactca tgccctgggc tgccctgagg acaatgggag gccatggtgg
4441 gacttcctct ccctactgag cccttccttt ctgcctggcc aggccaaggg gaatcctgag
4501 agcagcttca atgatgagaa cctgcgtgtg gtggtggctg acctgttcat ggcggggatg
4561 gtgaccacct ccaccacact gacctgggcc ctgctgttca tgatcctgca tccagatgtg
4621 cagtgtgagc ctggctgtgg ctgggaagaa aggaggagga ggatagagga ggcacactcc
4681 ttaagcgtac ttgggacact tgtggctccc agcactggtt tgacccagac tccaccaagg
4741 atggtggcca ccttactccc gtggacccag tccttatcat agaggtagtg gagggaaagg
4801 ggaaccctct gctgttcgtt aactgagcgg atgctgtcct tccaggccga gtacaacagg
4861 aaatcgatga ggtcataggg caggtgcggc gtccagagat ggcagaccag gcacgaatgc
4921 cgttcaccaa tgctgtcatc catgaggtgc agcgctttgc agacattctc cctcttggtg
4981 tgcctcacaa gacttctcgt gacattgaag tgcagggctt ccttatccct aaggtaagcc
5041 tgggtccccc cagtgtctaa gtcagtgttg ccagctaccc agtggcctga gctgctcagg
5101 taagaaggac tggactttac acaacccaat cctcaactcc acagaaccaa cttcccctgg
5161 gaagtatgag aggagaaaca agagcgacag ctgtacactg gaagccacag ctagaagggc
5221 aagcaaggga aaatatgaca gagtggttat aacagccacg acccacaaag acatgtgaca
5281 ccgtgtatac atctgtcgct tgtcacatat ccctgtcatg gcattaatga gagctgagaa
5341 acttctaggt ctgggtttac aagaaaggat ccagtgtgta aggtagaagc tgtgcctgtg
5401 aacatggtga ctacagtcta ggaagtcaca ccctgtccat gtccaaatca tgtgtctcct
5461 gccaggggac aaccctcatc accaacctgt cctcagtgct gaaggatgag accgtctggg
5521 agaagcccct ccgcttccac cctgaacact tcctggatgc ccagggcaac tttgtgaagc
5581 atgaggcctt catgccattc tcagcaggta cctctggggg gcctgactcc ctgtctattc
5641 ccagggtggc tgggagggtg gagctccaat caggccccag actgactgag cccctgtccc
5701 accacaggcc gcagagcatg cctgggggag cccctggccc gcatggagct cttcctcttc
5761 ttcacctgcc tcctgcagcg cttcagcttc tccgtgccca ctggacagcc ccggcccagc
5821 gactatggca tctttggtgc tctgaccacc ccgcgcccct accagctctg tgcttcaccc
5881 cgctaagggg aggcacagca tctcactcac tgtgcttgct ggggtcctag tgtgcaataa
5941 atggttttac tctgaaccga atcatccctg tgagctctcc aggctgtaag gggcctgagc
6001 agccttcccg tggacatccg cacccctact taatcttcct tgaccatgtg ccccaatgga
6061 agggctgctc tactgacctc cgaaatggca gccattcttg ctttcacccc tgccccctct
6121 tttcacccaa attgatgatg tttattcata gatgccaaca tctggaagga gggccagaaa
6181 ggactgctgt gaagggtcag tgtaagtcac acagatgagg gaaggggcgg tggaggtaat
6241 ggtgggcaga attgtcccct ttccacttga gatgtttctc ccagacgccc ccatttcaga
6301 cccactacac aaccaaggct aactcctcag ccagcatcat cacaacttct tatatgacgt
6361 cgcagagatg tagagaagtc ggggaggctg gaaatgacat gcaggttaag tgcccaaggt
6421 tacctgttgg gtaccacatg cttccctaaa cggttttgtg ggggtccaga agcaggttgc
6481 ctcctaagct tctttgtcac cattaattcc atgacccagc agggatactg gtgtccaggc
6541 ccatgcacag taagaaagtg actctaacca gggatggaag gacccgcaag cttagtgttg
6601 acacagactt ccagacctta gcacaactga ctccatggta gaagtaccat ttgggccata
6661 aaacttagca cgtagacagc agctcctctc ataatgaaaa caaagaccta atccatcaaa
6721 ttctatcctg ggaaggtctc ttgaagcact catcttggct tcttggcttc tgtagttctc
6781 ctagctaact gctcttgcta actgaagtat gtcaacccag gatatggttg ttggtaaaag
6841 ctcgccctga gaacagctca ggacgacatt gaggtgaccc agtgtagtca ccagccagct
6901 aataaagacc tccttttggt ttaaatccat atctgagtag tcttctctgg tgcatacctc
6961 acaccatttc taaaggttgc aacaagatcc ctagagacag accttgaggc accatgggtc
7021 tcagatcccc atggtgcaga gaagaggagt atggtagtct aggggctccc aggaagtgtg
7081 caaccagaag actttccagg gccttaggac tgcctttgat catttgctgc ctaaaagctt
7141 tctgacactg cacctccccc ccaaaagaaa caaactcaag tgttgcctgg tccgttacct
7201 ccagaggctc tgtgtccctc tgttaggtag ggctgaccca gtgtctggga tccaggtgag
7261 acattaccag actcccctgg cctgtttgta tgaatgtatg gtgaccaccc ctgcttgtct
7321 ttacgtgtgc ctttctatat gattctgtca gttctgtaga ctggagaaac atcgaaagta
7381 gaaagggaac agtcctgaca ctgttacccc cattcctttt cttttctttt cttttctttt
7441 cttttctttt cttttctttt cttttctttt ccggagctgg ggaccgaacc cagggccttg
7501 cacttgctag gcaagtgctc taccactgag ctaaatcccc aacccccccc ccccattcct
7561 ccctgcatgg ctcatgactt ccctcaggct catgggcagt ggctgttgct gctgctgttg
7621 ctatggcagt ggtggccact gggacccacc taaatctaca cgctaggctt ccccgtgcac
7681 aacaagctgt ccccattccc ctgttggcag gggccagtat catgggctct gccacagttg
7741 aaacttcagc cctagttaag ggggggggaa actttttaaa cactcagtac tcaaggaaca
7801 cagacctggg ccatggaaaa attctgcttc cacttggaag cccagttaga ttctttagct
7861 gaggttgctc ttcaaaatgg agaggattgg acctcctctt tttttttttt ttctggttct
7921 ttttttcgga gctggggacc gaacccaggg ccttgcgctt cctaggtaag cgctctacca
7981 ctgagctaaa gccccagccc ggacctcctc tttatgagac aagggagtct gtatataata
8041 caaaaaaaaa aaaaaaaatc tgtccattct gttgccgtca atcggagcta attagaagga
8101 tttagccatg gttaaaaata accttcgaga gggggagggg agggaagaga aactgcggtc
8161 aggatgtaat atatgagaga ggaataaaaa atcagactag gaggcgggga tagggaagaa
8221 tgggtggatg agcagcacag gatacagctc catttctggc caccactgtg acaactgatt
8281 gttcaaccct ggggaccttt ctgaacacct atcaggtaca aatgaaaact aggaaaataa
8341 agaggagagg ggacctttaa ttaaaacaaa caaacaaaca agcaccctta aaaataagga
8401 gacaggagag agacatcgaa atctaacagc cggtgccagt ctttgttctc cctggttaac
8461 tactctactt caggccatgg ctgggtcatc gatccttgta cttctggctc tccctgtagg
8521 atcctgatag cccaactgcc tacttagctc tataaaacaa aaataaagtc tgtcaaacta
8581 ttaatgctaa ggagacaaca taaccctgtt cccccagatg agttcatgat ctgactcatg
8641 cccatagaac cagtgaggag gaacatcgtg ggcccccagg ccttagcaca gctgacatca
8701 tgatgaaagg taccactcag gcccgggaac ccagcacata gacagcaaca ccctcctaag
8761 cagagaacag cttcaacggc ttgacctgcg tttttatatc ctctcagagt ctttcccact
8821 gaaagaccac acttcccaga tttcccagca gaccacggga gtcacatcca gcctatgaga
8881 gaccaaatcc catcttctgc aggcgtgttg gcttccacac atgagggtga caagatgccc
8941 ctcactgtga ataaacagcc ctgcctatgg tcagaccaca cctccctctc cctctctctc
9001 tctctctctc tctctctctc tctctccagc tgtttttaaa taatctaaca cttgggaaga
9061 cagggattga gccctgagag ctataggcct gccacaggaa agggttaacc ttagagccca
9121 tcaccagtga gacgggcaga gaaccgtggt ggtggcatgg gcgtcaccgc ttgagccttg
9181 ctgtggtgcc acactgaagc cagccagtct ttgcttttgt gggttcttct ttttcccacc
9241 ctttatcccc ctggtttcgc cccctatcac tagataggaa agaaaggata gaggggggag
9301 atagagatct ctgaatctaa tttatttctt tctagtttct aatttgagca ggacttacaa
9361 actgcaacca gtccctcccc caacccccac tcccaccctg ccctcgggct ctagcattta
9421 tattccctct gaaaagtccc cagaattc
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS RATIID4G 9448 bp ds-DNA ROD 22-MAY-1991
DEFINITION Rat P450 IID4 gene.
ACCESSION X52029 X52457
KEYWORDS Cytochrome P450; cytochrome; cytochrome P450 IID4.
SOURCE Rattus sp. DNA.
ORGANISM Rattus sp.
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 9448)
AUTHORS Matsunaga,E., Umeno,M. and Gonzalez,F.J.
TITLE The rat P450 IID subfamily: complete sequences of four closely
linked genes and evidence that gene conversions maintained sequence
homogeneity at the heme-binding region of the cytochrome P450
active site.
JOURNAL J. Mol. Evol. 30, 155-169 (1990)
STANDARD simple automatic
COMMENT From EMBL entry RSIID4G; dated 21-FEB-1991.
FEATURES Location/Qualifiers
mat_peptide join(1331..1519,2953..3124,3350..3502,3583..3743,
4123..4299,4483..4624,4846..5033,5466..5607,5708..5883)
/product="cytochrome P450 IID3 protein"
/gene="P450 IID4"
mRNA join(<1331..1519,2953..3124,3350..3502,3583..3743,
4123..4299,4483..4624,4846..5033,5466..5607,5708..>5886)
/gene="P450 IID4"
exon <1331..1519
/number=1
exon <1331..1519
CDS join(1331..1519,2953..3124,3350..3502,3583..3743,
4123..4299,4483..4624,4846..5033,5466..5607,5708..5886)
/product="cytochrome P450 IID3 protein"
/gene="P450 IID4"
/codon_start=1331
TATA_signal 1245..1247
prim_transcript 1277..>6034
/gene="P450 IID4"
intron 1520..2952
/number=1
exon 2953..3124
/number=2
exon 2953..3124
exon 2953..3124
exon 2953..3124
intron 3125..3349
/number=2
/cons_splice=(5'site:no,3'site:yes)
/note="gc instead of gt"
exon 3350..3502
/number=3
exon 3350..3502
exon 3350..3502
exon 3350..3502
intron 3503..3582
/number=3
exon 3583..3743
/number=4
exon 3583..3743
exon 3583..3743
exon 3583..3743
intron 3744..4122
/number=4
exon 4123..4299
/number=5
exon 4123..4299
exon 4123..4299
exon 4123..4299
intron 4300..4482
/number=5
exon 4483..4624
/number=6
exon 4483..4624
exon 4483..4624
exon 4483..4624
intron 4625..4845
/number=6
exon 4846..5033
/number=7
exon 4846..5033
exon 4846..5033
exon 4846..5033
intron 5034..5465
/number=7
exon 5466..5607
/number=8
exon 5466..5607
exon 5466..5607
exon 5466..5607
intron 5608..5707
/number=8
exon 5708..>5886
/number=9
exon 5708..>5886
polyA_signal 5936..5941
polyA_site 6034..6034
BASE COUNT 2337 a 2420 c 2465 g 2226 t
ORIGIN
1 gaattctgat ctgttaatat ttggggggat tgagcacaac agcatcgtca tttggggggc
61 acaaatgatg atttttttgc tgtgtatgtg tgctctgtag ctacttatca tccagggaca
121 gacatggttc tcccagctaa gaaagcagcc agagttgcta agtgacttcc tcaaaattgc
181 caaataatgc agctgtctgg aaatgagaaa ggaggtgggg cagaatgggg ggagggagct
241 tgatctcccc cctcgccccc cccccccggc gatgtgattt ccactcagca acgttgattg
301 taactcaaca agggaatgct ttttcctgtt tgggcctttg cccacaaaca aaggcgtttt
361 cataatatgc cgatggaatg tatcttggtt gcagacagcc gtagtctggc ttagaggcgg
421 tgaagctttt aggttagagt gtgtaagaag ctaatgctaa acttgctgac tctcggactt
481 gtgcggatgg ctcagagagc tagggtcttc attctagtgg acctggagtg gacagaggtc
541 tgtctgggtc actaggaaaa gcctagtttc ttctctttaa attttgatga ttgaatgagc
601 gagaggcctg ggagccttct gcagcgagtg caatcgctag catttgccaa ctgctcgcag
661 tggaagggta cgagacgcat ctgagctggc ttttggccat cctgtttgat gagaagtgtg
721 tgacaaagta aaatagggcc tgtgggagtg ggagacacca cataggagcc aagccaaact
781 ctgaagattg tctgatggct cagttcatat tacctgtact ccttgattct gtggagaacc
841 ttcctctaga taaggtcaca gacatccaag cgtcgactct cctgctgggg gcgggggagg
901 gggggagtca aacccttaat tatggctttc taattcccta cgccatcagt ggctattgcc
961 ctgggcctac aattttctgc cattcctctt gaaaagatgt tgctcttggg gagatgcaac
1021 acacaaacac acacacacac acacacacac acacacacac atacacacaa gcaagcatgc
1081 acacacgcat gcacaaacag aacttagaga aggagggatc tctaagacca aatgcccctg
1141 gcctgccttg aaccttcctt gcactctgca tggtcagtgc agccacttgg cttaaggcag
1201 aggagaaagg gcagctcggt cccttattga gtgcccaggg cctgataatg ctatcgttcc
1261 ttggtcctag gtggctgtag tcgggattga gaggtgtttc caaagaaacc caaagagcag
1321 cagggcagcc atgaggatgc cgacggggtc tgaactgtgg cccatagcca tattcacgat
1381 catcttcctg cttctggtgg acctgatgca caggcgccag cgctggactt ctcgctaccc
1441 tccgggccct gtgccctggc ctgtgctggg caacctgctg cagatagact tccagaatat
1501 gccagcgggc tttcaaaagg taagggaatt gttggtgggc aggagaggcc atggtgaccc
1561 cttattagaa caagtgagtg gtggtgaaac tgcatgctgg acacggagct ggtccccagg
1621 acaaagcggg ttaagaggct tctcctgggg ctggggattt agctcagtgg tagagcgctt
1681 acctaggaag cgcaaggccc tgggttcggt ccccagctcc gaaaaaaaga accaaaaaaa
1741 aaaaaaaaaa aaagaggctc ctcctgaaga gggtggtgca gaacccgaag actcactgga
1801 gtttccaaag gcaacagcta ggaggtgaga tgggtcctgg cagccgtctg agatccagtt
1861 aacaggatag gctgtaaggg ttggtggtga tgctggggtt gcattctgat cccagagcac
1921 ctgtagttgg gaggctaaag caggtaggtt atgaattcca tcttgaactg catagcgaaa
1981 ctctctctaa aatggagact taaaggccag ctgtggaggt gctcgcctct aagcccagcg
2041 cttaagagac agaggtgggc atatttcttt gagtcctagg ctagtctggt ctaacatact
2101 gagttccagg cccatgctac atagtgaaac tgtttccaaa agaaatctaa cattttaaaa
2161 ggaaaaaaac aatcaatgca gtggtggaga ctttcacagc attcacagga ggcaaaagcc
2221 agcagatctc tgtgaattca gcaccagctt gacctacata gaaagtccca agccgaccct
2281 agctacatac taagacaaaa attacacaca cacacacaca cacacacaca cacactgaat
2341 gaatgaatga atgaatgaat gaatggaaaa tcgagtcatc gagtcatata ggcttcatat
2401 tccttttcat tccactggag ggaaatgttt caagaatgca ggaaggggca ctggagggtg
2461 gctcagtggt taagagcact gactgctctt ccagaggtcc tgagttcaat tcccagcaac
2521 cacatggtgg ctataaccat ctataatggg atcaataccc tcttctggtt tgtctgaaga
2581 cagcaacaat ctattcatat acataaagtc ttttaaaaat ggggcggggc catgatccta
2641 aacgagtgtc tctgtcagga aatcaaagtt gagagacagg aagtgctgct cccatccttt
2701 tgctgtttcc gattctcagg ctcccctaca tctgtgaggc ttagtttcct catctagaca
2761 tggggatgcc agtgggacca accggcaaat gcgtgacacc agcaaggtcg gagtccaagg
2821 tggttcccca gacaaataat agatgtcatc cttctgtagg gctcgctctg ggtctccccg
2881 ccaagtcctg tctagtacag ctaagcgcgg taacccaggc ttgctggtaa caccctcact
2941 ccctgcctac agctgagatg tcgctttggg gacctgttca gcttacagct ggcctttgag
3001 tcggtggttg tactgaatgg gctgccagcc ctgcgagagg cactggtgaa atacagcgag
3061 gacaccgctg accggccacc gctgcatttc aatgaccagt cgggctttgg accacgctct
3121 caaggcaaat gcagacagtg gcaggagtgg tggggaaagg gagactagag agggctcggg
3181 gaccagaggc agtttgggac ctagttgagg tggaggaggg acaggaacgg agaaaagaca
3241 aggaaggcag acagctaacg ggtgagcaaa gggtctgaca gtggtggcag tgaagtagca
3301 taggggcagg aaagagggcg aggtctcagg cctaagtgtg gtactccagg tgtggtcctc
3361 gcgaggtatg gacctgcctg gcgtcagcag cggcgcttct ctgtgtccac cttccgtcac
3421 tttggcctgg gcaagaagtc actggagcag tgggtgacag aggaggccag atgcctctgt
3481 gctgccttcg ctgaccatag tggtaggtgg tggattggtg gggataggtg gggataggtg
3541 gggagagaca accaaggtcc tgactggcat ttctgctccc aggattccct ttcagcccta
3601 acactctact ggacaaagca gtgtgtaacg tgatcgcgtc cctcctcttt gcctgccgct
3661 ttgaatacaa tgacccacgc ttcatcaggc tcctggactt gctgaaggac actcttgagg
3721 aggaatctgg attcctgccc atggtacgag ggttggggtt ctctgtaccc agatgacttc
3781 agacagtgga gtctctcagg gagatgattg acatgcagga gtgacaggag gaggacattc
3841 tgggaggaga tggatacacg tcaatgggaa ggacggggta ggctagaagt gcctagaaat
3901 agtgagtgcc tgggctcctc atccatgtgg cagccacaca ggtctgtgac atttccacag
3961 tatgatgacc cttctggaag ctcagggcaa agaggaaagt cagaggctgg cagggaggga
4021 cgatgtcacc tgtctatcct ggaggacact gggaccaggg gctattgcaa gtgagcccgg
4081 ggccccctgg cctctccatt ggtccctctg tgctgcccac agctcctgaa tgtgttcccg
4141 atgctcctac acatcccagg gcttcttggc aaggtattct ctggaaagaa ggccttcgtt
4201 gccatgctgg acgagctgct aactgaacac aaggtgacct gggaccctgc gcagccaccc
4261 cgagatctga ctgatgcctt cctggctgag gtggagaagg tgattggcag ctccaagaga
4321 tgtagccgga agctatgggc tgaggtcctg tgagctgtga ggccagatgg gtagggtcct
4381 gtgtatcacc aagtgactca tgccctgggc tgccctgagg acaatgggag gccatggtgg
4441 gacttcctct ccctactgag cccttccttt ctgcctggcc aggccaaggg gaatcctgag
4501 agcagcttca atgatgagaa cctgcgtgtg gtggtggctg acctgttcat ggcggggatg
4561 gtgaccacct ccaccacact gacctgggcc ctgctgttca tgatcctgca tccagatgtg
4621 cagtgtgagc ctggctgtgg ctgggaagaa aggaggagga ggatagagga ggcacactcc
4681 ttaagcgtac ttgggacact tgtggctccc agcactggtt tgacccagac tccaccaagg
4741 atggtggcca ccttactccc gtggacccag tccttatcat agaggtagtg gagggaaagg
4801 ggaaccctct gctgttcgtt aactgagcgg atgctgtcct tccaggccga gtacaacagg
4861 aaatcgatga ggtcataggg caggtgcggc gtccagagat ggcagaccag gcacgaatgc
4921 cgttcaccaa tgctgtcatc catgaggtgc agcgctttgc agacattctc cctcttggtg
4981 tgcctcacaa gacttctcgt gacattgaag tgcagggctt ccttatccct aaggtaagcc
5041 tgggtccccc cagtgtctaa gtcagtgttg ccagctaccc agtggcctga gctgctcagg
5101 taagaaggac tggactttac acaacccaat cctcaactcc acagaaccaa cttcccctgg
5161 gaagtatgag aggagaaaca agagcgacag ctgtacactg gaagccacag ctagaagggc
5221 aagcaaggga aaatatgaca gagtggttat aacagccacg acccacaaag acatgtgaca
5281 ccgtgtatac atctgtcgct tgtcacatat ccctgtcatg gcattaatga gagctgagaa
5341 acttctaggt ctgggtttac aagaaaggat ccagtgtgta aggtagaagc tgtgcctgtg
5401 aacatggtga ctacagtcta ggaagtcaca ccctgtccat gtccaaatca tgtgtctcct
5461 gccaggggac aaccctcatc accaacctgt cctcagtgct gaaggatgag accgtctggg
5521 agaagcccct ccgcttccac cctgaacact tcctggatgc ccagggcaac tttgtgaagc
5581 atgaggcctt catgccattc tcagcaggta cctctggggg gcctgactcc ctgtctattc
5641 ccagggtggc tgggagggtg gagctccaat caggccccag actgactgag cccctgtccc
5701 accacaggcc gcagagcatg cctgggggag cccctggccc gcatggagct cttcctcttc
5761 ttcacctgcc tcctgcagcg cttcagcttc tccgtgccca ctggacagcc ccggcccagc
5821 gactatggca tctttggtgc tctgaccacc ccgcgcccct accagctctg tgcttcaccc
5881 cgctaagggg aggcacagca tctcactcac tgtgcttgct ggggtcctag tgtgcaataa
5941 atggttttac tctgaaccga atcatccctg tgagctctcc aggctgtaag gggcctgagc
6001 agccttcccg tggacatccg cacccctact taatcttcct tgaccatgtg ccccaatgga
6061 agggctgctc tactgacctc cgaaatggca gccattcttg ctttcacccc tgccccctct
6121 tttcacccaa attgatgatg tttattcata gatgccaaca tctggaagga gggccagaaa
6181 ggactgctgt gaagggtcag tgtaagtcac acagatgagg gaaggggcgg tggaggtaat
6241 ggtgggcaga attgtcccct ttccacttga gatgtttctc ccagacgccc ccatttcaga
6301 cccactacac aaccaaggct aactcctcag ccagcatcat cacaacttct tatatgacgt
6361 cgcagagatg tagagaagtc ggggaggctg gaaatgacat gcaggttaag tgcccaaggt
6421 tacctgttgg gtaccacatg cttccctaaa cggttttgtg ggggtccaga agcaggttgc
6481 ctcctaagct tctttgtcac cattaattcc atgacccagc agggatactg gtgtccaggc
6541 ccatgcacag taagaaagtg actctaacca gggatggaag gacccgcaag cttagtgttg
6601 acacagactt ccagacctta gcacaactga ctccatggta gaagtaccat ttgggccata
6661 aaacttagca cgtagacagc agctcctctc ataatgaaaa caaagaccta atccatcaaa
6721 ttctatcctg ggaaggtctc ttgaagcact catcttggct tcttggcttc tgtagttctc
6781 ctagctaact gctcttgcta actgaagtat gtcaacccag gatatggttg ttggtaaaag
6841 ctcgccctga gaacagctca ggacgacatt gaggtgaccc agtgtagtca ccagccagct
6901 aataaagacc tccttttggt ttaaatccat atctgagtag tcttctctgg tgcatacctc
6961 acaccatttc taaaggttgc aacaagatcc ctagagacag accttgaggc accatgggtc
7021 tcagatcccc atggtgcaga gaagaggagt atggtagtct aggggctccc aggaagtgtg
7081 caaccagaag actttccagg gccttaggac tgcctttgat catttgctgc ctaaaagctt
7141 tctgacactg cacctccccc ccaaaagaaa caaactcaag tgttgcctgg tccgttacct
7201 ccagaggctc tgtgtccctc tgttaggtag ggctgaccca gtgtctggga tccaggtgag
7261 acattaccag actcccctgg cctgtttgta tgaatgtatg gtgaccaccc ctgcttgtct
7321 ttacgtgtgc ctttctatat gattctgtca gttctgtaga ctggagaaac atcgaaagta
7381 gaaagggaac agtcctgaca ctgttacccc cattcctttt cttttctttt cttttctttt
7441 cttttctttt cttttctttt cttttctttt ccggagctgg ggaccgaacc cagggccttg
7501 cacttgctag gcaagtgctc taccactgag ctaaatcccc aacccccccc ccccattcct
7561 ccctgcatgg ctcatgactt ccctcaggct catgggcagt ggctgttgct gctgctgttg
7621 ctatggcagt ggtggccact gggacccacc taaatctaca cgctaggctt ccccgtgcac
7681 aacaagctgt ccccattccc ctgttggcag gggccagtat catgggctct gccacagttg
7741 aaacttcagc cctagttaag ggggggggaa actttttaaa cactcagtac tcaaggaaca
7801 cagacctggg ccatggaaaa attctgcttc cacttggaag cccagttaga ttctttagct
7861 gaggttgctc ttcaaaatgg agaggattgg acctcctctt tttttttttt ttctggttct
7921 ttttttcgga gctggggacc gaacccaggg ccttgcgctt cctaggtaag cgctctacca
7981 ctgagctaaa gccccagccc ggacctcctc tttatgagac aagggagtct gtatataata
8041 caaaaaaaaa aaaaaaaatc tgtccattct gttgccgtca atcggagcta attagaagga
8101 tttagccatg gttaaaaata accttcgaga gggggagggg agggaagaga aactgcggtc
8161 aggatgtaat atatgagaga ggaataaaaa atcagactag gaggcgggga tagggaagaa
8221 tgggtggatg agcagcacag gatacagctc catttctggc caccactgtg acaactgatt
8281 gttcaaccct ggggaccttt ctgaacacct atcaggtaca aatgaaaact aggaaaataa
8341 agaggagagg ggacctttaa ttaaaacaaa caaacaaaca agcaccctta aaaataagga
8401 gacaggagag agacatcgaa atctaacagc cggtgccagt ctttgttctc cctggttaac
8461 tactctactt caggccatgg ctgggtcatc gatccttgta cttctggctc tccctgtagg
8521 atcctgatag cccaactgcc tacttagctc tataaaacaa aaataaagtc tgtcaaacta
8581 ttaatgctaa ggagacaaca taaccctgtt cccccagatg agttcatgat ctgactcatg
8641 cccatagaac cagtgaggag gaacatcgtg ggcccccagg ccttagcaca gctgacatca
8701 tgatgaaagg taccactcag gcccgggaac ccagcacata gacagcaaca ccctcctaag
8761 cagagaacag cttcaacggc ttgacctgcg tttttatatc ctctcagagt ctttcccact
8821 gaaagaccac acttcccaga tttcccagca gaccacggga gtcacatcca gcctatgaga
8881 gaccaaatcc catcttctgc aggcgtgttg gcttccacac atgagggtga caagatgccc
8941 ctcactgtga ataaacagcc ctgcctatgg tcagaccaca cctccctctc cctctctctc
9001 tctctctctc tctctctctc tctctccagc tgtttttaaa taatctaaca cttgggaaga
9061 cagggattga gccctgagag ctataggcct gccacaggaa agggttaacc ttagagccca
9121 tcaccagtga gacgggcaga gaaccgtggt ggtggcatgg gcgtcaccgc ttgagccttg
9181 ctgtggtgcc acactgaagc cagccagtct ttgcttttgt gggttcttct ttttcccacc
9241 ctttatcccc ctggtttcgc cccctatcac tagataggaa agaaaggata gaggggggag
9301 atagagatct ctgaatctaa tttatttctt tctagtttct aatttgagca ggacttacaa
9361 actgcaacca gtccctcccc caacccccac tcccaccctg ccctcgggct ctagcattta
9421 tattccctct gaaaagtccc cagaattc
//