GenBank-Updates@genbank.bio.net (03/08/91)
LOCUS NGOGYRB 2555 bp ds-DNA BCT 08-MAR-1991
DEFINITION N.gonorrhoeae DNA gyrase (gyrB) gene, complete cds.
ACCESSION M59981
KEYWORDS DNA gyrase.
SOURCE N.gonorrhoeae (strain MUG 116) DNA.
ORGANISM Unclassified.
Unclassified.
REFERENCE 1 (bases 1 to 2555)
AUTHORS Stein,D.C., Danaher,R. and Cook,T.M.
TITLE Characterization of a gyrB mutation responsible for low level
nalidixic acid resistance in Neisseria gonorrheae
JOURNAL Antimicrob. Agents Chemother. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 76..2421
/function="DNA supercoiling"
/standard_name="gyrase"
/product="DNA gyrase"
/gene="gyrB"
/evidence=EXPERIMENTAL
/codon_start=76
BASE COUNT 685 a 782 c 644 g 444 t
ORIGIN
1 ttccgcccgc tttttccaca aggtgcggac tgttttggcg gcatcgcaaa atcttttcaa
61 aatccggcaa aaaatatgac tgaacaaaaa cacgaagaat acggcgccga cagcatccag
121 gtgctcgaag gcttggaagc ggtaccgaaa cgccccggca tgtacatcgg cgacacgcag
181 gacggcagcg gcctgcacca tatggtgttt gaagtattgg acaacgccat cgacgaagca
241 ctcgccggac attgcgacaa aatcacggta acgatacacg ccgaccattc cgtcagcgtc
301 gccgacaacg ggcgcggtat gcccaccggc atccacccga aagaagggcg ttccgccgcc
361 gaagtcatca tgaccgtctt gcacgcgggc ggcaaattcg acaacaacag ctacaaaatc
421 tccggcggcc tgcacggcgt gggcgtatcc gtcgtcaacg cgctgtccga ctgggtaacg
481 ctgaccatct accgcgacgg caaagaacac ttcgtccgct tcgtacgcgg cgaaaccgaa
541 gagccgctga aaattgtcgg cgattccgac aaaaaaggca cgaccgtgcg cttcctcgcc
601 ggcacggaaa ccttcggcaa tatcgaatac agcttcgaca tcctcgccaa acgtattcgc
661 gaactttcgt tcctaaacaa cggcgtggac atcgaattga ccgacgagcg cgacggcaag
721 cacgaaagct tcgccctttc cggcggcgtg gcgggcttcg tgcaatacat gaaccgcaaa
781 aaaacgccct tgcacgaaaa aatcttctat gcgttcggcg agaaagacgg catgagcgtc
841 gaatgcgcaa tgcaatggaa cgacagctat caggaaagcg tgcagtgctt caccaacaac
901 atccctcagc gcgacggcgg tacgcacctg accgcgctgc gccaagtgat gacgcgcacc
961 atcaacagct acatcgaagc taacgaagtc gccaaaaaag ccaaagtgga aaccgccggc
1021 gacgatatgc gcgaaggttt gacctgcgtg ttgtccgtca aactgcccga ccccaaattc
1081 tcatcccaaa ccaaagacaa actggtttcc ggcgaaatcg gccccgttgt caacgaagtc
1141 atcaaccaag cactaaccga cttcctcgaa gaaaatccga acgaagccaa aatcatcacc
1201 ggcaaaatcg tcgatgccgc ccgcgcacgg caagccgccc gcaaagcccg cgaaatcacc
1261 cgccgcaaag ggctgatgga cggcttggga ctgcccggca aactcgccga ctgccaggaa
1321 aaagaccctg ccctgtctga actctacctc gtcgagggca actccgcagg cggttccgcc
1381 atgcagggcc gcgaccgcaa attccaagcg attttgccgc tcaaaggtaa aattttgaac
1441 gtcgccaccc tgattaccgc gctgggtgca ggcatcggca aagaagagtt caaccctgaa
1501 aaactacgct accaccgcat catcatcatg accgatgccg acgtggacgg tgcgcacatc
1561 cggaccctgc tcctgacctt cttctaccgc caaatgcccg acctggtcga gcgcggctac
1621 atttacatcg cccagccgcc gctctacaaa gccaaatacg gcaagcagga gcgttacctc
1681 aaagacgaac tggaaaaaga ccaatggctg ctcggccttg ccttggaaaa agccaaaatc
1741 gtttcagacg gccgcaccat cgaaggcgca gaacttgccg acaccgccaa acaattcttg
1801 ttggcgaaaa ccgtcatcga acaggaaagc cgcttcgtgg acgaactcgt cctgcgtgcc
1861 atgctgcacg cgtcgcccat tgatttgacg tcgtctgaaa acgccgataa agccgttgcc
1921 gaactttccg gtttgcttga cgaaaaagaa gccgccctcg aacgcatcga aggtcatgaa
1981 ggacaccagt tcatcaaaat cacgcgcaag ctgcacggca acgtcatggt cagctacatc
2041 gaacccaagt tcctcaacag caaagcctac caaaccctca cccaaaccgc cgccgcgctc
2101 aaaggcttgg tcggcgaggg cgccaagctc tacaaaggcg agaacgagta cgacgcggac
2161 agctttgaaa ccgctttgga catcttgatg agcgttgccc aaaaaggtat gtccatccaa
2221 cgatacaaag gtttgggcga gatgaacccc gagcagcttt gggaaaccac gatggatccc
2281 accgtgcgcc gcctgttgaa agtgcgcatc gaagatcgca ttgccgacga agtgttcgtt
2341 accctgatgg gcgacgaggt cgaaccgcgc cgcgccttta tcgaaaacaa tgcgctgatt
2401 gcgcaaaata tcgacgcata agtgccgttt taaaaaagga gacgggcagc ttgccgcgtc
2461 tccttttggt ttgtcaaacg gaagccatgc cgtctgaaac cgcctttcgg agcaaaacca
2521 tgatcagcat ttttgatatt tcaaatcggt atcgg
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS NGOGYRB 2555 bp ds-DNA BCT 22-MAY-1991
DEFINITION N.gonorrhoeae DNA gyrase (gyrB) gene, complete cds.
ACCESSION M59981
KEYWORDS DNA gyrase.
SOURCE N.gonorrhoeae (strain MUG 116) DNA.
ORGANISM Neisseria gonorrhoeae
Prokaryota; Bacteria; Gracilicutes; Scotobacteria; Neisseriaceae.
REFERENCE 1 (bases 1 to 2555)
AUTHORS Stein,D.C., Danaher,R. and Cook,T.M.
TITLE Characterization of a gyrB mutation responsible for low level
nalidixic acid resistance in Neisseria gonorrheae
JOURNAL Antimicrob. Agents Chemother. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 76..2421
/function="DNA supercoiling"
/standard_name="gyrase"
/product="DNA gyrase"
/gene="gyrB"
/evidence=EXPERIMENTAL
/codon_start=76
BASE COUNT 685 a 782 c 644 g 444 t
ORIGIN
1 ttccgcccgc tttttccaca aggtgcggac tgttttggcg gcatcgcaaa atcttttcaa
61 aatccggcaa aaaatatgac tgaacaaaaa cacgaagaat acggcgccga cagcatccag
121 gtgctcgaag gcttggaagc ggtaccgaaa cgccccggca tgtacatcgg cgacacgcag
181 gacggcagcg gcctgcacca tatggtgttt gaagtattgg acaacgccat cgacgaagca
241 ctcgccggac attgcgacaa aatcacggta acgatacacg ccgaccattc cgtcagcgtc
301 gccgacaacg ggcgcggtat gcccaccggc atccacccga aagaagggcg ttccgccgcc
361 gaagtcatca tgaccgtctt gcacgcgggc ggcaaattcg acaacaacag ctacaaaatc
421 tccggcggcc tgcacggcgt gggcgtatcc gtcgtcaacg cgctgtccga ctgggtaacg
481 ctgaccatct accgcgacgg caaagaacac ttcgtccgct tcgtacgcgg cgaaaccgaa
541 gagccgctga aaattgtcgg cgattccgac aaaaaaggca cgaccgtgcg cttcctcgcc
601 ggcacggaaa ccttcggcaa tatcgaatac agcttcgaca tcctcgccaa acgtattcgc
661 gaactttcgt tcctaaacaa cggcgtggac atcgaattga ccgacgagcg cgacggcaag
721 cacgaaagct tcgccctttc cggcggcgtg gcgggcttcg tgcaatacat gaaccgcaaa
781 aaaacgccct tgcacgaaaa aatcttctat gcgttcggcg agaaagacgg catgagcgtc
841 gaatgcgcaa tgcaatggaa cgacagctat caggaaagcg tgcagtgctt caccaacaac
901 atccctcagc gcgacggcgg tacgcacctg accgcgctgc gccaagtgat gacgcgcacc
961 atcaacagct acatcgaagc taacgaagtc gccaaaaaag ccaaagtgga aaccgccggc
1021 gacgatatgc gcgaaggttt gacctgcgtg ttgtccgtca aactgcccga ccccaaattc
1081 tcatcccaaa ccaaagacaa actggtttcc ggcgaaatcg gccccgttgt caacgaagtc
1141 atcaaccaag cactaaccga cttcctcgaa gaaaatccga acgaagccaa aatcatcacc
1201 ggcaaaatcg tcgatgccgc ccgcgcacgg caagccgccc gcaaagcccg cgaaatcacc
1261 cgccgcaaag ggctgatgga cggcttggga ctgcccggca aactcgccga ctgccaggaa
1321 aaagaccctg ccctgtctga actctacctc gtcgagggca actccgcagg cggttccgcc
1381 atgcagggcc gcgaccgcaa attccaagcg attttgccgc tcaaaggtaa aattttgaac
1441 gtcgccaccc tgattaccgc gctgggtgca ggcatcggca aagaagagtt caaccctgaa
1501 aaactacgct accaccgcat catcatcatg accgatgccg acgtggacgg tgcgcacatc
1561 cggaccctgc tcctgacctt cttctaccgc caaatgcccg acctggtcga gcgcggctac
1621 atttacatcg cccagccgcc gctctacaaa gccaaatacg gcaagcagga gcgttacctc
1681 aaagacgaac tggaaaaaga ccaatggctg ctcggccttg ccttggaaaa agccaaaatc
1741 gtttcagacg gccgcaccat cgaaggcgca gaacttgccg acaccgccaa acaattcttg
1801 ttggcgaaaa ccgtcatcga acaggaaagc cgcttcgtgg acgaactcgt cctgcgtgcc
1861 atgctgcacg cgtcgcccat tgatttgacg tcgtctgaaa acgccgataa agccgttgcc
1921 gaactttccg gtttgcttga cgaaaaagaa gccgccctcg aacgcatcga aggtcatgaa
1981 ggacaccagt tcatcaaaat cacgcgcaag ctgcacggca acgtcatggt cagctacatc
2041 gaacccaagt tcctcaacag caaagcctac caaaccctca cccaaaccgc cgccgcgctc
2101 aaaggcttgg tcggcgaggg cgccaagctc tacaaaggcg agaacgagta cgacgcggac
2161 agctttgaaa ccgctttgga catcttgatg agcgttgccc aaaaaggtat gtccatccaa
2221 cgatacaaag gtttgggcga gatgaacccc gagcagcttt gggaaaccac gatggatccc
2281 accgtgcgcc gcctgttgaa agtgcgcatc gaagatcgca ttgccgacga agtgttcgtt
2341 accctgatgg gcgacgaggt cgaaccgcgc cgcgccttta tcgaaaacaa tgcgctgatt
2401 gcgcaaaata tcgacgcata agtgccgttt taaaaaagga gacgggcagc ttgccgcgtc
2461 tccttttggt ttgtcaaacg gaagccatgc cgtctgaaac cgcctttcgg agcaaaacca
2521 tgatcagcat ttttgatatt tcaaatcggt atcgg
//