GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR3 95 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 11.
ACCESSION M55027
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 95)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..95
/number=11
/gene="CFTR gene"
/codon_start=1
mutation 68..68
/note="replace(68,'a')"
/gene="CFTR gene"
/label=G551D
BASE COUNT 34 a 15 c 24 g 22 t
ORIGIN Chromosome 7q31-q32.
1 gacatctcca agtttgcaga gaaagacaat atagttcttg gagaaggtgg aatcacactg
61 agtggagatc aacgagcaag aatttcttta gcaag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR4 87 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 12.
ACCESSION M55028
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 87)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..87
/number=12
/gene="CFTR gene"
/codon_start=1
mutation 42..42
/note="replace(42,'a')"
/gene="CFTR gene"
/label=P574H
BASE COUNT 33 a 9 c 15 g 30 t
ORIGIN Chromosome 7q31-q32.
1 agcagtatac aaagatgctg atttgtattt attagactct cattttggat acctagatgt
61 tttaacagaa aaagaaatat ttgaaag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR5 95 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 11.
ACCESSION M55029
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 95)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..95
/number=11
/gene="CFTR gene"
/codon_start=1
mutation 95..95
/note="replace(95,'c')"
/gene="CFTR gene"
/label=R560T
BASE COUNT 33 a 16 c 24 g 22 t
ORIGIN Chromosome 7q31-q32.
1 gacatctcca agtttgcaga gaaagacaat atagttcttg gagaaggtgg aatcacactg
61 agtggaggtc aacgagcaag aatttcttta gcaac
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR6 95 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 11.
ACCESSION M55030
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 95)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..95
/number=11
/gene="CFTR gene"
/codon_start=1
mutation 63..63
/note="replace(63,'g')"
/gene="CFTR gene"
/label=S549R
BASE COUNT 33 a 15 c 26 g 21 t
ORIGIN Chromosome 7q31-q32.
1 gacatctcca agtttgcaga gaaagacaat atagttcttg gagaaggtgg aatcacactg
61 aggggaggtc aacgagcaag aatttcttta gcaag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR7 87 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 12.
ACCESSION M55031
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 87)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..87
/number=12
/gene="CFTR gene"
/codon_start=1
mutation 8..8
/note="replace(8,'a')"
/gene="CFTR gene"
/label=Y563N
BASE COUNT 33 a 10 c 15 g 29 t
ORIGIN Chromosome 7q31-q32.
1 agcagtaaac aaagatgctg atttgtattt attagactct ccttttggat acctagatgt
61 tttaacagaa aaagaaatat ttgaaag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR1 206 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 10.
ACCESSION M55025
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 206)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
mutation 7..7
/note="replace(7,'a')"
/gene="CFTR gene"
/label=1717-
exon 8..199
/number=10
/gene="CFTR gene"
/codon_start=8
BASE COUNT 68 a 35 c 42 g 61 t
ORIGIN Chromosome 7q31-q32.
1 tttccaaact tcacttctaa tgatgattat gggagaactg gagccttcag agggtaaaat
61 taagcacagt ggaagaattt cattctgttc tcagttttcc tggattatgc ctggcaccat
121 taaagaaaat atcatctttg gtgtttccta tgatgaatat agatacagaa gcgtcatcaa
181 agcatgccaa ctagaagagg taagaa
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR9 95 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 11.
ACCESSION M55033
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 95)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..95
/number=11
/gene="CFTR gene"
/codon_start=1
mutation 40..40
/note="replace(40,'t')"
/gene="CFTR gene"
/label=G542X
BASE COUNT 33 a 15 c 24 g 23 t
ORIGIN Chromosome 7q31-q32.
1 gacatctcca agtttgcaga gaaagacaat atagttcttt gagaaggtgg aatcacactg
61 agtggaggtc aacgagcaag aatttcttta gcaag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR2 183 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 9.
ACCESSION M55026
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 183)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..183
/number=9
/gene="CFTR gene"
/evidence=EXPERIMENTAL
/codon_start=1
mutation 155..155
/note="replace(155,'a')"
/gene="CFTR gene"
/evidence=EXPERIMENTAL
/label=A455E
BASE COUNT 62 a 29 c 41 g 51 t
ORIGIN Chromosome 7q31-q32.
1 ggatttgggg aattatttga gaaagcaaaa caaaacaata acaatagaaa aacttctaat
61 ggtgatgaca gcctcttctt cagtaatttc tcacttcttg gtactcctgt cctgaaagat
121 attaatttca agatagaaag aggacagttg ttggaggttg ctggatccac tggagcaggc
181 aag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR12 95 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 11.
ACCESSION M55036
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 95)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..95
/number=11
/gene="CFTR gene"
/codon_start=1
mutation 62..62
/note="replace(62,'t')"
/gene="CFTR gene"
/label=S549I
BASE COUNT 33 a 15 c 24 g 23 t
ORIGIN Chromosome 7q31-q32.
1 gacatctcca agtttgcaga gaaagacaat atagttcttg gagaaggtgg aatcacactg
61 attggaggtc aacgagcaag aatttcttta gcaag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR10 203 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 10.
ACCESSION M55034
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 203)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 8..199
/number=10
/gene="CFTR gene"
/codon_start=8
mutation 130..131
/note="replace(130.131,'tatca')"
/gene="CFTR gene"
BASE COUNT 66 a 34 c 43 g 60 t
ORIGIN Chromosome 7q31-q32.
1 tttccagact tcacttctaa tgatgattat gggagaactg gagccttcag agggtaaaat
61 taagcacagt ggaagaattt cattctgttc tcagttttcc tggattatgc ctggcaccat
121 taaagaaaat atctttggtg tttcctatga tgaatataga tacagaagcg tcatcaaagc
181 atgccaacta gaagaggtaa gaa
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR8 249 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 19.
ACCESSION M55032
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 249)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..249
/number=19
/gene="CFTR gene"
/codon_start=1
mutation 58..59
/note="replace(58.59,'acc')"
/gene="CFTR gene"
/label=3659d
BASE COUNT 88 a 54 c 53 g 54 t
ORIGIN Chromosome 7q31-q32.
1 gatgcgatct gtgagccgag tctttaagtt cattgacatg ccaacagaag gtaaacctac
61 aagtcaacca aaccatacaa gaatggccaa ctctcgaaag ttatgattat tgagaattca
121 cacgtgaaga aagatgacat ctggccctca gggggccaaa tgactgtcaa agatctcaca
181 gcaaaataca cagaaggtgg aaatgccata ttagagaaca tttccttctc aataagtcct
241 ggccagagg
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR13 156 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 20.
ACCESSION M55037
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 156)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 1..156
/number=20
/gene="CFTR gene"
/codon_start=1
mutation 129..129
/note="replace(129,'a')"
/gene="CFTR gene"
/label=W1282
BASE COUNT 45 a 25 c 44 g 42 t
ORIGIN Chromosome 7q31-q32.
1 gtgggcctct tgggaagaac tggatcaggg aagagtactt tgttatcagc ttttttgaga
61 ctactgaaca ctgaaggaga aatccagatc gatggtgtgt cttgggattc aataactttg
121 caacagtgaa ggaaagcctt tggagtgata ccacag
//GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMCFTR11 206 bp ds-DNA PRI 16-JAN-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 10.
ACCESSION M55035
KEYWORDS cystic fibrosis; transmembrane conductance regulator.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 206)
AUTHORS Kerem,B.-S., Zielenski,J., Markiewicz,D., Bozon,D., Gazit,E.,
Yahav,J., Kennedy,D., Riordan,J.R., Collins,F.S., Rommens,J.M. and
Tsui,L.-C.
TITLE Identification of mutations in regions corresponding to the two
putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 8447-8451 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 8..199
/number=10
/gene="CFTR gene"
/codon_start=8
mutation 92..92
/note="replace(92,'t')"
/gene="CFTR gene"
/label=Q493X
BASE COUNT 67 a 34 c 43 g 62 t
ORIGIN Chromosome 7q31-q32.
1 tttccagact tcacttctaa tgatgattat gggagaactg gagccttcag agggtaaaat
61 taagcacagt ggaagaattt cattctgttc ttagttttcc tggattatgc ctggcaccat
121 taaagaaaat atcatctttg gtgtttccta tgatgaatat agatacagaa gcgtcatcaa
181 agcatgccaa ctagaagagg taagaa
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA01 1577 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 1.
ACCESSION M55106 M55499
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1577)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
REFERENCE 2 (sites)
AUTHORS Zielenski,J., Bozon,D., Kerem,B.-S., Markiewicz,D., Durie,P.,
Rommens,J.M. and Tsui,L.-C.
TITLE Identification of mutations in exons 1 through 8 of the cystic
fibrosis transmembrane conductance regulator (CFTR) gene
JOURNAL Genomics 10, 229-235 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
exon <829..881
/number=1
/gene="CFTR gene"
mutation 825..825
/note="replace (825, 'c')"
/label=129
/citation=Genomics 10, 229-235 (1991)
BASE COUNT 449 a 303 c 461 g 364 t
ORIGIN Map position 7q31-q32.
1 ccacccttgg agttcactca cctaaacctc aaactaataa agcttggttc ttttctccga
61 cacgcaaagg aagcgctaag gtaaatgcat cagacccaca ctgccgcgga acttttcggc
121 tctctaaggc tgtattttga tatacgaaag gcacattttc cttccctttt caaaatgcac
181 cttgcaaacg taacagggac ccgactagga tcatcgggaa aaggaggagg aggaggaagg
241 caggctccgg ggaagctggt ggcagcgggt cctgggtctg gcggaccctg acgcgaagga
301 gggtctagga agctctccgg ggagccgttc tcccgccggt ggcttcttct gtcctccagc
361 gttgccaact ggacctaaag agaggccgcg actgtcgccc acctgcggga tgggcctggt
421 gctgggcggt aaggacacgg acctggaagg agcgcgcgcg agggagggag gctgggagtc
481 agaatcggga aagggaggtg cggggcggcg agggagcgaa ggaggagagg aggaaggagc
541 gggaggggtg ctggcggggg tgcgtagtgg gtggagaaag ccgctagagc aaatttgggg
601 ccggaccagg cagcactcgg cttttaacct gggcagtgaa ggcgggggaa agagcaaaag
661 gaaggggtgg tgtgcggagt aggggtgggt ggggggaatt ggaagccaaa tgacatcaca
721 gcaggtcaga gaaaaagggt tgagcggcag gcacccagag tagtaggtct ttggcattag
781 gagcttgagc ccagacggcc ctagcaggga ccccagcgcc cagagaccat gcagaggtcg
841 cctctggaaa aggccagcgt tgtctccaaa ctttttttca ggtgagaagg tggccaaccg
901 agcttcggaa agacacgtgc ccacgaaaga ggagggcgtg tgtatgggtt gggtttgggg
961 taaaggaata agcagttttt aaaaagatgc gctatcattc attgttttga aagaaaatgt
1021 gggtattgta gaataaaaca gaaagcatta agaagagatg gaagaatgaa ctgaagctga
1081 ttgaatagag agccacatct acttgcaact gaaaagttag aatctcaaga ctcaagtacg
1141 ctactatgca cttgttttat ttcatttttc taagaaacta aaaatacttg ttaataagta
1201 cctagtatgg tttattggtt ttcccccttc atgccttgga cacttgattg tcttcttggc
1261 acatacaggt gccatgcctg catatagtaa gtgctcagaa aacatttctt gactgaattc
1321 agccaacaaa aattttgggg taggtagaaa atatatgctt aaagtattta ttgttatgag
1381 actggatata tctagtattt gtcacaggta aatgattctt caaaaattga aagcaaattt
1441 gttgaaatat ttattttgaa aaaagttact tcacaagcta taaattttaa aagccatagg
1501 aatagatacc gaagttatat ccaactgaca tttaataaat tgtattcata gcctaatgtg
1561 atgagccaca gaagctt
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA02 630 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 2.
ACCESSION M55107
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 630)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55106:882..>1577,<1..250)
/number=1
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 251..361
/number=2
/gene="CFTR gene"
BASE COUNT 209 a 102 c 121 g 198 t
ORIGIN Map position 7q31-q32.
1 aaaccatact attattccct cccaatccct ttgacaaagt gacagtcaca ttagttcaga
61 gatattgatg ttttatacag gtgtagcctg taagagatga agcctggtat ttatagaaat
121 tgacttattt tattctcata tttacatgtg cataattttc catatgccag aaaagttgaa
181 tagtatcaga ttccaaatct gtatggagac caaatcaagt gaatatctgt tcctcctctc
241 tttattttag ctggaccaga ccaattttga ggaaaggata cagacagcgc ctggaattgt
301 cagacatata ccaaatccct tctgttgatt ctgctgacaa tctatctgaa aaattggaaa
361 ggtatgttca tgtacattgt ttagttgaag agagaaattc atattattaa ttatttagag
421 aagagaaagc aaacatatta taagtttaat tcttatattt aaaaatagga gccaagtatg
481 gtggctaatg cctgtaatcc caactatttg ggaggccaag atgagaggat tgcttgagac
541 caggagtttg ataccagcct gggcaacata gcaagatgtt atctctacac aaaataaaaa
601 gttagctggg aatggtagtg catgcttgta
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA03 454 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 3.
ACCESSION M55108 M55504 M55505
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 3 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 454)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
REFERENCE 2 (sites)
AUTHORS Zielenski,J., Bozon,D., Kerem,B.-S., Markiewicz,D., Durie,P.,
Rommens,J.M. and Tsui,L.-C.
TITLE Identification of mutations in exons 1 through 8 of the cystic
fibrosis transmembrane conductance regulator (CFTR) gene
JOURNAL Genomics 10, 229-235 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
intron order(M55107:362..>630,<1..184)
/number=2
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 185..293
/number=3
/gene="CFTR gene"
variation 244..244
/note="replace (244, 'a')"
/label=R75Q
/citation=Genomics 10, 229-235 (1991)
mutation 274..274
/note="replace (274, 'a')"
/label=G85E
/citation=Genomics 10, 229-235 (1991)
BASE COUNT 145 a 68 c 87 g 154 t
ORIGIN Map position 7q31-q32.
1 aggaatctgc cagatatctg gctgagtgtt tggtgttgta tggtctccat gagattttgt
61 ctctataata cttgggttaa tctccttgga tatacttgtg tgaatcaaac tatgttaagg
121 gaaataggac aactaaaata tttgcacatg caacttattg gtcccacttt ttattctttt
181 gcagagaatg ggatagagag ctggcttcaa agaaaaatcc taaactcatt aatgcccttc
241 ggcgatgttt tttctggaga tttatgttct atggaatctt tttatattta ggggtaagga
301 tctcatttgt acattcatta tgtatcacat aactatatgc atttttgtga ttatgaaaag
361 actacgaaat ctggtgaata ggtgtaaaaa tataaaggat gaatccaact ccaaacacta
421 agaaaccacc taaaactcta gtaaggataa gtaa
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA04 674 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 4.
ACCESSION M55109 M55500 M55501
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 4 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 674)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
REFERENCE 2 (sites)
AUTHORS Zielenski,J., Bozon,D., Kerem,B.-S., Markiewicz,D., Durie,P.,
Rommens,J.M. and Tsui,L.-C.
TITLE Identification of mutations in exons 1 through 8 of the cystic
fibrosis transmembrane conductance regulator (CFTR) gene
JOURNAL Genomics 10, 229-235 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
intron order(M55108:294..>454,<1..252)
/number=3
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 253..468
/number=4
/gene="CFTR gene"
mutation 403..403
/note="replace (403, ' ')"
/label=556delA
/citation=Genomics 10, 229-235 (1991)
mutation 469..469
/note="replace (469, 't')"
/label=621+1G-T
/citation=Genomics 10, 229-235 (1991)
BASE COUNT 212 a 122 c 111 g 229 t
ORIGIN Map position q31-q32.
1 ccactattca ctgtttaact taaaatacct catatgtaaa cttgtctccc actgttgcta
61 taacaaatcc caagtcttat ttcaaagtac caagatattg aaaatagtgc taagagtttc
121 acatatggta tgaccctcta tataaactca ttttaagtct cctctaaaga tgaaaagtct
181 tgtgttgaaa ttctcagggt attttatgag aaataaatga aatttaattt ctctgttttt
241 ccccttttgt aggaagtcac caaagcagta cagcctctct tactgggaag aatcatagct
301 tcctatgacc cggataacaa ggaggaacgc tctatcgcga tttatctagg cataggctta
361 tgccttctct ttattgtgag gacactgctc ctacacccag ccatttttgg ccttcatcac
421 attggaatgc agatgagaat agctatgttt agtttgattt ataagaaggt aatacttcct
481 tgcacaggcc ccatggcaca tatattctgt atcgtacatg ttttaatgtc ataaattagg
541 tagtgagctg gtacaagtaa gggataaatg ctgaaattaa tttaatatgc ctattaaata
601 aatggcagga ataattaatg ctcttaatta tccttgataa tttaattgac ttaaactgat
661 aattattgag tatc
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA05 600 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 5.
ACCESSION M55110 M55502 M55503
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 5 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 600)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
REFERENCE 2 (sites)
AUTHORS Zielenski,J., Bozon,D., Kerem,B.-S., Markiewicz,D., Durie,P.,
Rommens,J.M. and Tsui,L.-C.
TITLE Identification of mutations in exons 1 through 8 of the cystic
fibrosis transmembrane conductance regulator (CFTR) gene
JOURNAL Genomics 10, 229-235 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
intron order(M55109:469..>674,<1..242)
/number=4
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 243..332
/number=5
/gene="CFTR gene"
mutation 285..285
/note="replace (285, 'a')"
/label=G178R
/citation=Genomics 10, 229-235 (1991)
mutation 333..333
/note="replace (333, 't')"
/label=711+1G-T
/citation=Genomics 10, 229-235 (1991)
BASE COUNT 197 a 94 c 95 g 214 t
ORIGIN Map position q31-q32.
1 taattatttc tgcctagatg ctgggaaata aaacaactag aagcatgcca gtataatatt
61 gactgttgaa agaaacattt atgaacctga gaagatagta agctagatga atagaatata
121 attttcatta cctttactta ataatgaatg cataataact gaattagtca tattataatt
181 ttacttataa tatatttgta ttttgtttgt tgaaattatc taactttcca tttttctttt
241 agactttaaa gctgtcaagc cgtgttctag ataaaataag tattggacaa cttgttagtc
301 tcctttccaa caacctgaac aaatttgatg aagtatgtac ctattgattt aatcttttag
361 gcactattgt tataaattat acaactggaa aggcggagtt ttcctgggtc agataatagt
421 aattagtggt taagtcttgc tcagctctag cttccctatt ctggaaacta agaaaggtca
481 attgtatagc agagcaccat tctggggtct ggtagaacca cccaactcaa aggcacctta
541 gcctgttgtt aataagattt ttcaaaactt aattcttatc agaccttgct tcttttaaac
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA06 2078 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exons 6a and b.
ACCESSION M55111
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 6 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2078)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55110:333..>600,<1..285)
/number=5
/note="gap of unknown legnth"
/gene="CFTR gene"
intron 286..449
/number=6a
/gene="CFTR gene"
exon 286..449
/number=6a
/gene="CFTR gene"
exon 1582..1707
/number=6b
/gene="CFTR gene"
BASE COUNT 602 a 360 c 405 g 711 t
ORIGIN Map position 7q31-q32.
1 gacatgatac ttaagatgtc caatcttgat tccactgaat aaaaatatgc ttaaaaatgc
61 actgacttga aatttgtttt ttgggaaaac cgattctatg tgtagaatgt ttaagcacat
121 tgctatgtgc tccatgtaat gattacctag attttagtgt gctcagaacc acgaagtgtt
181 tgatcatata agctcctttt acttgctttc tttcatatat gattgttagt ttctaggggt
241 ggaagataca atgacacctg tttttgctgt gcttttattt tccagggact tgcattggca
301 catttcgtgt ggatcgctcc tttgcaagtg gcactcctca tggggctaat ctgggagttg
361 ttacaggcgt ctgccttctg tggacttggt ttcctgatag tccttgccct ttttcaggct
421 gggctaggga gaatgatgat gaagtacagg tagcaaccta ttttcataac ttgaaagttt
481 taaaaattat gttttcaaaa agcccacttt agtaaaacca ggactgctct atgcatagaa
541 cagtgatctt cagtgtcatt aaattttttt tttttttttt tttgagacag agtctagatc
601 tgtcacccag gctggagtgc agtggcacga tcttggctca ctgcactgca acttctgcct
661 cccaggctca agcaattctc ctgcctcagc ctccggagta gctgggatta gaggcgcatg
721 caccacaccc agctaatttt tgtattttag tagagacagg gtttcaccag gttgcccagg
781 ctggtctcga atgcctgacc tcaggtgatc cgcccacctc ggcctcccaa agtactgata
841 ttacaggcat gagctaccgc gcccggccta aaaaatactt tttaagatgg tgtaaatatt
901 actttctgta tcaatggtac attttttact tgtcagtctc tagaatttct ttataaatat
961 gttgattcag ttcatttttg tagattataa aacaggtaaa aaaggataaa acatttatgt
1021 gaattaaagg gaatacctaa tttttgtgta gagtttatta gcttttacta ctctggttta
1081 tggatcatca caccagagcc ttagttactt tgtgttacag aataactaat atgagtgaat
1141 gaatgactta cacaagtcac tgcttaggat aaagggcttg agtttgtcag ctagagtatg
1201 acagaaagta tctaagtttt ggagtcaaat agcactttgt ttgaatccca gattgcatgc
1261 ttactagtta tgtgacctta gtcaagccac ttcacctcac tgagtctttg cttttttcat
1321 ctctaaaata gagataccca ccgctcatag gctgtcataa ggatagagat agcatatgga
1381 atgagtctgt acagcgtctg gcacatagga ggcatttacc aaacagtagt tattattttt
1441 gttaccatct atttgataat aaaataatgc ccatctgttg aataaaagaa atatgactta
1501 aaaccttgag cagttcttaa tagataattt gacttgtttt tactattaga ttgattgatt
1561 gattgattga ttgatttaca gagatcagag agctgggaag atcagtgaaa gacttgtgat
1621 tacctcagaa atgattgaaa atatccaatc tgttaaggca tactgctggg aagaagcaat
1681 ggaaaaaatg attgaaaact taagacagta agttgttcca ataatttcaa tattgttagt
1741 aattctgtcc ttaatttttt aaaaatatgt ttatcatggt agacttccac ctcatatttg
1801 atgtttgtga caatcaaatg attgcattta agttctgtca atattcatgc attagttgca
1861 caaattcact ttcatgggct gtagttttat gtagttggtc cagggtgtta ttttatgctg
1921 caagtatatt atactgatac gttattaaag aatttcctac atatgttcac tgctgctcaa
1981 tacatttatt tcgttaaaaa caattatcaa gatactgaag gctgattggt aactcacatg
2041 gaactgggag agtatacaat tctgaaccaa atagatga
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA07 752 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 7.
ACCESSION M55112
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 7 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 752)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(487..>752,<1..239)
/number=6b
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 240..486
/number=7
/gene="CFTR gene"
BASE COUNT 247 a 144 c 133 g 228 t
ORIGIN Map position 7q31-q32.
1 tttacaagta ctacaagcaa aacactggta ctttcattgt tatcttttca tataaggtaa
61 ctgaggccca gagagattaa ataacatgcc caaggtcaca caggtcatat gatgtggagc
121 caggttaaaa atataggcag aaagactcta gagaccatgc tcagatcttc cattccaaga
181 tccctgatat ttgaaaaata aaataacatc ctgaatttta ttgttattgt tttttataga
241 acagaactga aactgactcg gaaggcagcc tatgtgagat acttcaatag ctcagccttc
301 ttcttctcag ggttctttgt ggtgttttta tctgtgcttc cctatgcact aatcaaagga
361 atcatcctcc ggaaaatatt caccaccatc tcattctgca ttgttctgcg catggcggtc
421 actcggcaat ttccctgggc tgtacaaaca tggtatgact ctcttggagc aataaacaaa
481 atacaggtaa tgtaccataa tgctgcatta tatactatga tttaaataat cagtcaatag
541 atcagttcta atgaactttg caaaaatgtg cgaaaagata gaaaaagaaa tttccttcac
601 taggaagtta taaaagttgc cagctaatac taggaatgtt caccttaaac ttttcctagc
661 atttctctgg acagtatgat ggatgagagt ggcatttatg caaattacct taaaatccca
721 ataatactga tgtagctagc agctttgaga aa
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA08 725 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 8.
ACCESSION M55113
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 8 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 725)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55112:487..>752,<1..335)
/number=7
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 336..428
/number=8
/gene="CFTR gene"
BASE COUNT 261 a 97 c 136 g 231 t
ORIGIN Map position 7q31-q32.
1 gcacattagt gggtaattca gggttgcttt gtaaattcat cactaaggtt agcatgtaat
61 agtacaagga agaatcagtt gtatgttaaa tctaatgtat aaaaagtttt ataaaatatc
121 atatgtttag agagtatatt tcaaatatga tgaatcctag tgcttggcaa attaacttta
181 gaacactaat aaaattattt tattaagaaa taattactat ttcattatta aaattcatat
241 ataagatgta gcacaatgag agtataaagt agatgtaata atgcattaat gctattctga
301 ttctataata tgtttttgct ctcttttata aataggattt cttacaaaag caagaatata
361 agacattgga atataactta acgactacag aagtagtgat ggagaatgta acagccttct
421 gggaggaggt cagaattttt aaaaaattgt ttgctctaaa cacctaactg ttttcttctt
481 tgtgaatatg gatttcatcc taatggcgaa taaaattaga atgatgatat aactggtaga
541 actggaagga ggatcactca cttattttct agattaagaa gtagaggaat ggccaggtgc
601 tcatggttgt aatcccagca ctttcgggag accaaggcgg gtggatcacc tgaggtcagg
661 agttcaagac cagcctgcca acatggtaaa acccggtctc tactaaaaat acaaaaaatt
721 aactg
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA09 1056 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 9.
ACCESSION M55114
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 9 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1056)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55113:429..>725,<1..460)
/number=8
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 461..643
/number=9
/gene="CFTR gene"
BASE COUNT 309 a 155 c 200 g 392 t
ORIGIN Map position 7q31-q32.
1 ggtagtgact ttaaagctgt gtgactttag tcatttaact gctgagtcac agtctacagc
61 tttgaaagag gaggattata aaatctatct catgttaatg ctgaagatta aataatagtg
121 tttatgtacc ccgcttatag gagaagaggg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
181 tgtatgtgta tgtatacatg tatgtattca gtctttactg aaattaaaaa atctttaact
241 tgataatggg caaatatctt agttttagat catgtcctct agaaaccgta tgctatataa
301 ttatgtacta taaagtaata atgtatacag tgtaatggat catgggccat gtgcttttca
361 aactaattgt acataaaaca agcatctatt gaaaatatct gacaaactca tcttttattt
421 ttgatgtgtg tgtgtgtgtg tgtgtgtgtt tttttaacag ggatttgggg aattatttga
481 gaaagcaaaa caaaacaata acaatagaaa aacttctaat ggtgatgaca gcctcttctt
541 cagtaatttc tcacttcttg gtactcctgt cctgaaagat attaatttca agatagaaag
601 aggacagttg ttggcggttg ctggatccac tggagcaggc aaggtagttc ttttgttctt
661 cactattaag aacttaattt ggtgtccatg tctctttttt tttctagttt gtagtgctgg
721 aaggtatttt tggagaaatt cttacatgag cattaggaga atgtatgggt gtagtgtctt
781 gtataataga aattgttcca ctgataattt actctagttt tttatttcct catattattt
841 tcagtggctt tttcttccac atctttatat tttgcaccac attcaacact gtatcttgca
901 catggcgagc attcaataac tttattgaat aaacaaatca tccattttat ccattcttaa
961 ccagaacaga cattttttca gagctggtcc aggaaaatca tgacttacat tttgccttag
1021 taaccacata aacaaaaagt ctccattttt gttgac
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA10 831 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 10.
ACCESSION M55115
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 10 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 831)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55114:644..>1056,<1..307)
/number=9
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 308..499
/number=10
/gene="CFTR gene"
BASE COUNT 263 a 140 c 141 g 287 t
ORIGIN Map position 7q31-q32.
1 cactgtagct gtactacctt ccatctcctc aacctattcc aactatctga atcatgtgcc
61 cttctctgtg aacctctatc ataatacttg tcacactgta ttgtaattgt ctcttttact
121 ttcccttgta tcttttgtgc atagcagagt acctgaaaca ggaagtattt taaatatttt
181 gaatcaaatg agttaataga atctttacaa ataagaatat acacttctgc ttaggatgat
241 aattggaggc aagtgaatcc tgagcgtgat ttgataatga cctaataatg atgggtttta
301 tttccagact tcacttctaa tgatgattat gggagaactg gagccttcag agggtaaaat
361 taagcacagt ggaagaattt cattctgttc tcagttttcc tggattatgc ctggcaccat
421 taaagaaaat atcatctttg gtgtttccta tgatgaatat agatacagaa gcgtcatcaa
481 agcatgccaa ctagaagagg taagaaacta tgtgaaaact ttttgattat gcatatgaac
541 ccttcacact acccaaatta tatatttggc tccatattca atcggttagt ctacatatat
601 ttatgtttcc tctatgggta agctactgtg aatggatcaa ttaataaaac acatgaccta
661 tgctttaaga agcttgcaaa cacatgaaat aaatgcaatt tattttttaa ataatgggtt
721 catttgatca caataaatgc attttatgaa atggtgagaa ttttgttcac tcattagtga
781 gacaaacgtc tcaatggtta tttatatggc atgcatatag tgatatgtgg t
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA11 614 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 11.
ACCESSION M55116
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 11 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 614)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55115:308..>831,<1..294)
/number=10
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 295..389
/number=11
/gene="CFTR gene"
BASE COUNT 213 a 77 c 108 g 216 t
ORIGIN Map position 7q31-q32.
1 atatacccat aaatatacac atattttaat ttttggtatt ttataattat tatttaatga
61 tcattcatga cattttaaaa attacaggaa aaatttacat ctaaaatttc agcaatgttg
121 tttttgacca actaaataaa ttgcatttga aataatggag atgcaatgtt caaaatttca
181 actgtggtta aagcaatagt gtgatatatg attacattag aaggaagatg tgcctttcaa
241 attcagattg agcatactaa aagtgactct ctaattttct atttttggta ataggacatc
301 tccaagtttg cagagaaaga caatatagtt cttggagaag gtggaatcac actgagtgga
361 ggtcaacgag caagaatttc tttagcaagg tgaataacta attattggtc tagcaagcat
421 ttgctgtaaa tgtcattcat gtaaaaaaat tacagacatt tctctattgc tttatattct
481 gtttctggaa ttgaaaaaat cctggggttt tatggctagt gggttaagaa tcacatttaa
541 gaactataaa taatggtata gtatccagat ttggtagaga ttatggttac tcagaatctg
601 tgcccgtatc ttgg
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA12 676 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 12.
ACCESSION M55117
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 12 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 676)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron (M55116:390..>614,<1..283)
/number=11
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 284..370
/number=12
/gene="CFTR gene"
BASE COUNT 214 a 115 c 107 g 240 t
ORIGIN Map position 7q31-q32.
1 cttacagtta gcaaaatcac ttcagcagtt cttggaatgt tgtgaaaagt gataaaaatc
61 ttctgcaact tattccttta ttcctcattt aaaataatct accatagtaa aaacatgtat
121 aaaagtgcta cttctgcacc acttttgaga atagtgttat ttcagtgaat cgatgtggtg
181 accatattgt aatgcatgta gtgaactgtt taaggcaaat catctacact agatgaccag
241 gaaatagaga ggaaatgtaa tttaatttcc attttctttt tagagcagta tacaaagatg
301 ctgatttgta tttattagac tctccttttg gatacctaga tgttttaaca gaaaaagaaa
361 tatttgaaag gtatgttctt tgaatacctt acttataatg ctcatgctaa aataaaagaa
421 agacagactg tcccatcata gattgcattt tacctcttga gaaatatgtt caccattgtt
481 ggtatggcag aatgtagcat ggtattaact caaatctgat ctgccctact gggccaggat
541 tcaagattac ttccattaaa accttttctc accgcctcat gctaaaccag tttctctcat
601 tgctatactg ttatagcaat tgctatctat gtagtttttg cagtatcatt gccttgtgat
661 atatattact ttaatt
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA13 1213 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 13.
ACCESSION M55118
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 13 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1213)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55117:371..>676,<1..176)
/number=12
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 177..900
/number=13
/gene="CFTR gene"
BASE COUNT 440 a 212 c 223 g 338 t
ORIGIN Map position 7q31-q32.
1 gaattcacaa ggtaccaatt taattactac agagtactta tagaatcatt taaaatataa
61 taaaattgta tgatagagat tatatgcaat aaaacattaa caaaatgcta aaatacgaga
121 catattgcaa taaagtattt ataaaattga tatttatatg tttttatatc ttaaagctgt
181 gtctgtaaac tgatggctaa caaaactagg attttggtca cttctaaaat ggaacattta
241 aagaaagctg acaaaatatt aattttgcat gaaggtagca gctattttta tgggacattt
301 tcagaactcc aaaatctaca gccagacttt agctcaaaac tcatgggatg tgattctttc
361 gaccaattta gtgcagaaag aagaaattca atcctaactg agaccttaca ccgtttctca
421 ttagaaggag atgctcctgt ctcctggaca gaaacaaaaa aacaatcttt taaacagact
481 ggagagtttg gggaaaaaag gaagaattct attctcaatc caatcaactc tatacgaaaa
541 ttttccattg tgcaaaagac tcccttacaa atgaatggca tcgaagagga ttctgatgag
601 cctttagaga gaaggctgtc cttagtacca gattctgagc agggagaggc gatactgcct
661 cgcatcagcg tgatcagcac tggccccacg cttcaggcac gaaggaggca gtctgtcctg
721 aacctgatga cacactcagt taaccaaggt cagaacattc accgaaagac aacagcatcc
781 acacgaaaag tgtcactggc ccctcaggca aacttgactg aactggatat atattcaaga
841 aggttatctc aagaaactgg cttggaaata agtgaagaaa ttaacgaaga agacttaaag
901 gtaggtatac atcgcttggg ggtatttcac cccacagaat gcaattgagt agaatgcaat
961 atgtagcatg taacaaaatt tactaaaatc ataggattag gataaggtgt atcttaaaac
1021 tcagaaagta tgaagttcat taattataca agcaacgtta aaatgtaaaa taacaaatga
1081 tttctttttg caatggacat atctcttccc ataaaatggg aaaggattta gtttttggtc
1141 ctctactaag ccagtgataa ctgtgactat agttagaaag catttgcttt attaccatct
1201 tgaaccctct gtg
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA14 734 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 14a.
ACCESSION M55119
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 14 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 734)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55118:901..>1213,<1..348)
/number=13
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 349..477
/number=14a
/gene="CFTR gene"
BASE COUNT 256 a 94 c 110 g 274 t
ORIGIN Map position 7q31-q32.
1 ggaaacttca tttagatggt atcattcatt tgataaaagg tatgccactg ttaagccttt
61 aatggtaaaa ttgtccaata ataatacagt tatataatca gtgatacatt tttagaattt
121 tgaaaaatta cgatgtttct catttttaat aaagctgtgt tgctccagta gacattattc
181 tggctataga atgacatcat acatggcatt tataatgatt tatatttgtt aaaatacact
241 tagattcaag taatactatt cttttatttt catatattaa aaataaaacc acaatggtgg
301 catgaaactg tactgtctta ttgtaatagc cataattctt ttattcagga gtgctttttt
361 gatgatatgg agagcatacc agcagtgact acatggaaca cataccttcg atatattact
421 gtccacaaga gcttaatttt tgtgctaatt tggtgcttag taatttttct ggcagaggta
481 agaatgttct attgtaaagt attactggat ttaaagttaa attaagatag tttggggatg
541 tatacatata tatgcacaca cataaatatg tatatataca catgtataca tgtataagta
601 tgcatatata cacacatata tcactatatg tatatatgta tatattacat atatttgtga
661 ttttacagta tataatggta tagattcata tagttcttag cttctgaaaa atcaacaagt
721 agaaccacta ctga
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA15 621 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 14b.
ACCESSION M55120
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 15 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 621)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55119:478..>734,<1..219)
/number=14a
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 220..257
/number=14b
/gene="CFTR gene"
BASE COUNT 178 a 104 c 142 g 197 t
ORIGIN Map position 7q31-q32.
1 gaattccatt aacttaatgt ggtctcatca caaataatag tacttagaac acctagtaca
61 gctgctggac ccaggaacac aaagcaaagg aagatgaaat tgtgtgtacc ttgatattgg
121 tacacacatc aaatggtgtg atgtgaattt agatgtgggc atgggaggaa taggtgaaga
181 tgttagaaaa aaaatcaact gtgtcttgtt ccattccagg tggctgcttc tttggttgtg
241 ctgtggctcc ttggaaagtg agtattccat gtcctattgt gtagattgtg ttttatttct
301 gttgattaaa tattgtaatc cactatgttt gtatgtattg taatccactt tgtttcattt
361 ctcccaagca ttatggtagt ggaaagataa ggttttttgt ttaaatgatg accattagtt
421 gggtgaggtg acacattcct gtagtcctag ctcctccaca ggctgacgca ggaggatcac
481 ttgagcccag gagttcaggg ctgtagtgtt gtatcattgt gagtagccac caccgcactc
541 cagcctggac aatatagtga gatcctatat ctaaaataaa ataaaataaa atgaataaat
601 tgtgagcatg tgcagctcct g
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA16 727 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 15.
ACCESSION M55121
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 16 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 727)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55120:258..>621,<1..362)
/number=14b
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 363..613
/number=15
/gene="CFTR gene"
BASE COUNT 226 a 128 c 124 g 249 t
ORIGIN Map position 7q31-q32.
1 tcctatatct aaataaataa ataaatgaat aaattgtgag catgtgcagc tcctgcagtt
61 tctaaagaat atagttctgt tcagtttctg tgaaacacaa taaaaatatt tgaaataaca
121 ttacatattt agggttttct tcaaattttt taatttaata aagaacaact caatctctat
181 caatagtgag aaaacatatc tattttcttg caataatagt atgattttga ggttaagggt
241 gcatgctctt ctaatgcaaa atattgtatt tatttagact caagtttagt tccatttaca
301 tgtattggaa attcagtaag taactttggc tgccaaataa cgatttccta tttgctttac
361 agcactcctc ttcaagacaa agggaatagt actcatagta gaaataacag ctatgcagtg
421 attatcacca gcaccagttc gtattatgtg ttttacattt acgtgggagt agccgacact
481 ttgcttgcta tgggattctt cagaggtcta ccactggtgc atactctaat cacagtgtcg
541 aaaattttac accacaaaat gttacattct gttcttcaag cacctatgtc aaccctcaac
601 acgttgaaag caggtacttt actaggtcta agaaatgaaa ctgctgatcc accatcaata
661 gggcctgtgg ttttgttggt tttctaatgg cagtgctggc ttttgcacag aggcatgtgc
721 ctttgtt
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA17 701 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 16.
ACCESSION M55122
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 17 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 701)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55121:614..>727,<1..325)
/number=15
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 326..405
/number=16
/gene="CFTR gene"
BASE COUNT 239 a 103 c 114 g 245 t
ORIGIN Map position 7q31-q32.
1 gtaagattgt aagcaggatg agtacccacc tattcctgac ataatttata gtaaaagcta
61 tttcagagaa attggtcgtt acttgaatct tacaagaatc tgaaactttt aaaaaggttt
121 aaaagtaaaa gacaataact tgaacacata attatttaga atgtttggaa agaaacaaaa
181 atttctaagt ctatctgatt ctatttgcta attcttattt gggttctgaa tgcgtctact
241 gtgatccaaa cttagtattg aatatattga tatatcttta aaaaattagt gttttttgag
301 gaatttgtca tcttgtatat tataggtggg attcttaata gattctccaa agatatagca
361 attttggatg accttctgcc tcttaccata tttgacttca tccaggtatg taaaaataag
421 taccgttaag tatgtctgta ttattaaaaa aacaataaca aaagcaaatg tgattttgtt
481 ttcatttttt atttgattga gggttgaagt cctgtctatt gcattaattt tgtaattatc
541 caaagccttc aaaatagaca taagtttagt aaattcaata ataagtcaga actgcttacc
601 tggcccaaac ctgaggcaat cccacattta gatgtaatag ctgtctactt gggagtgatt
661 tgagaggcac aaaggaccat ctttcccaaa atcactggca c
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA18 637 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 17a.
ACCESSION M55123
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 18 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 637)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55122:406..>701,<1..212)
/number=16
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 213..363
/number=17a
/gene="CFTR gene"
BASE COUNT 226 a 101 c 95 g 215 t
ORIGIN Map position 7q31-q32.
1 agtgcaccag catggcacat gtatacatat gtaactaacc tcgacaatgt gcacatgtac
61 cctaaaactt aaagtataat aaaaaaaata aaaaaaagtt tgaggtgttt aaagtatgca
121 aaaaaaaaaa aagaaataaa tcactgacac actttgtcca ctttgcaatg tgaaaatgtt
181 tactcaccaa catgttttct ttgatcttac agttgttatt aattgtgatt ggagctatag
241 cagttgtcgc agttttacaa ccctacatct ttgttgcaac agtgccagtg atagtggctt
301 ttattatgtt gagagcatat ttcctccaaa cctcacagca actcaaacaa ctggaatctg
361 aaggtatgac agtgaatgtg cgatactcat cttgtaaaaa agctataaga gctatttgag
421 attctttatt gttaatctac ttaaaaaaaa ttctgctttt aaacttttac atcatataac
481 aataattttt ttctacatgc atgtgtatat aaaaggaaac tatattacaa agtacacatg
541 gatttttttt cttaattaat gaccatgtga cttcattttg gttttaaaat aggtatatag
601 aatcttacca cagttggtgt acaggacatt catttat
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA19 858 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 17b.
ACCESSION M55124
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 19 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 858)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55123:364..>637,<1..155)
/number=17a
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 156..383
/number=17b
/gene="CFTR gene"
BASE COUNT 277 a 141 c 129 g 311 t
ORIGIN Map position 7q31-q32.
1 ttcaaagaat ggcaccagtg tgaaaaaaag ctttttaacc aatgacattt gtgatatgat
61 tattctaatt tagtcttttt caggtacaag atattatgaa aattacattt tgtgtttatg
121 ttatttgcaa tgttttctat ggaaatattt cacaggcagg agtccaattt tcactcatct
181 tgttacaagc ttaaaaggac tatggacact tcgtgccttc ggacggcagc cttactttga
241 aactctgttc cacaaagctc tgaatttaca tactgccaac tggttcttgt acctgtcaac
301 actgcgctgg ttccaaatga gaatagaaat gatttttgtc atcttcttca ttgctgttac
361 cttcatttcc attttaacaa caggtactat gaactcatta actttagcta agcatttaag
421 taaaaaattt tcaatgaata aaatgctgca ttctataggt tatcaatttt tgatatcttt
481 agagtttagt aattaacaaa tttgttggtt tattattgaa caagtgattt ctttgaaatt
541 tccattgttt tattgttaaa caaataattt ccttgaaatc ggtatatata tatatatagt
601 atatatatat atatatatat atatatacat atatatatat agtattatcc ctgttttcac
661 agttttaaaa accgatgcac acagattgtc gagtagcaat tctgtgattg aaggggaaat
721 atgtcacctc ttcatactca tattggtgaa gggtcctagc ttcaaaatta atagattcct
781 aaagagggga aatgaaacac cgcatttaca cacacacaca cacacacaca cacagagttc
841 ctcttgtcgg taagtttg
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA20 739 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 18.
ACCESSION M55125
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 20 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 739)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55124:384..>858,<1..334)
/number=17b
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 335..435
/number=18
/gene="CFTR gene"
BASE COUNT 252 a 115 c 134 g 238 t
ORIGIN Map position 7q31-q32.
1 ttattactta tagaataata gtagaagaga caaatatggt acctacccat taccaacaac
61 acctccaata ccagtaacat tttttaaaaa gggcaacact ttcctaatat tcaatcgctc
121 tttgatttaa aatcctggtt gaatacttac tatatgcaga gcattattct attagtagat
181 gctgtgatga actgagattt aaaaattgtt aaaattagca taaaattgaa atgtaaattt
241 aatgtgatat gtgccctagg agaagtgtga ataaagtcgt tcacagaaga gagaaataac
301 atgaggttca tttacgtctt ttgtgcatct ataggagaag gagaaggaag agttggtatt
361 atcctgactt tagccatgaa tatcatgagt acattgcagt gggctgtaaa ctccagcata
421 gatgtggata gcttggtaag tcttatcatc tttttaactt ttatgaaaaa aattcagaca
481 agtaacaaag tatgagtaat agcatgagga agaactatat accgtatatt gagcttaaga
541 aataaaacat tacagataaa ttgagggtca ctgtgtatct gtcattaaat ccttatctct
601 tctttccttc tcatagatag ccactatgaa gatctaatac tgcagtgagc attctttcac
661 ctgtttcctt attcaggatt ttctaggaga aatacctagg ggttgtattg ctgggtcata
721 ggattcaccc atgcttaac
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA21 629 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 19.
ACCESSION M55126
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 21 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 629)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55125:436..>739,<1..185)
/number=18
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 186..434
/number=19
/gene="CFTR gene"
BASE COUNT 214 a 107 c 109 g 199 t
ORIGIN Map position 7q31-q32.
1 ttctcttcag ttaaactttt aattatatcc aattatttcc tgttagttca ttgaaaagcc
61 cgacaaataa ccaagtgaca aatagcaagt gttgcatttt acaagttatt ttttaggaag
121 catcaaacta attgtgaaat tgtctgccat tcttaaaaac aaaaatgttg ttatttttat
181 ttcagatgcg atctgtgagc cgagtcttta agttcattga catgccaaca gaaggtaaac
241 ctaccaagtc aaccaaacca tacaagaatg gccaactctc gaaagttatg attattgaga
301 attcacacgt gaagaaagat gacatctggc cctcaggggg ccaaatgact gtcaaagatc
361 tcacagcaaa atacacagaa ggtggaaatg ccatattaga gaacatttcc ttctcaataa
421 gtcctggcca gagggtgaga tttgaacact gcttgctttg ttagactgtg ttcagtaagt
481 gaatcccagt agcctgaagc aatgtgttag cagaatctat ttgtaacatt attattgtac
541 agtagaatca atattaaaca cacatgtttt attatatgga gtcattattt ttaatatgaa
601 atttaatttg cagagtctga actatatat
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA22 605 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 20.
ACCESSION M55127
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 22 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 605)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55126:435..>629,<1..266)
/number=19
/note="gap of unknown legnth"
/gene="CFTR gene"
/partial
exon 267..422
/number=20
/gene="CFTR gene"
BASE COUNT 182 a 97 c 129 g 197 t
ORIGIN Map position 7q31-q32.
1 aaaggtcagt gataaaggaa gtctgcatca ggggtccaat tccttatggc cagtttctct
61 attctgttcc aaggttgttt gtctccatat atcaacattg gtcaggattg aaagtgtgca
121 acaaggtttg aatgaataag tgaaaatctt ccactggtga caggataaaa tattccaatg
181 gtttttattg aagtacaata ctgaattatg tttatggcat ggtacctata tgtcacagaa
241 gtgatcccat cacttttacc ttataggtgg gcctcttggg aagaactgga tcagggaaga
301 gtactttgtt atcagctttt ttgagactac tgaacactga aggagaaatc cagatcgatg
361 gtgtgtcttg ggattcaata actttgcaac agtggaggaa agcctttgga gtgataccac
421 aggtgagcaa aaggacttag ccagaaaaaa ggcaactaaa ttatattttt tactgctatt
481 tgatacttgt actcaagaaa ttcatattac tctgcaaaat atatttgtta tgcattgctg
541 tctttttttt ctccagtgca gttttctcat aggcagaaaa gatgtctcta aaagtttggg
601 aattc
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA23 716 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 21.
ACCESSION M55128
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 23 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 716)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55127:423..>605,<1..293)
/number=20
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 294..383
/number=21
/gene="CFTR gene"
BASE COUNT 246 a 110 c 120 g 240 t
ORIGIN Map position 7q31-q32.
1 tttttaatat tctacaatta acaattatct caatttcttt attctaaaga cattggatta
61 gaaaaatgtt cacaagggac tccaaatatt gctgtagtat ttgtttctta aaagaatgat
121 acaaagcaga catgataaaa tattaaaatt tgagagaact tgatggtaag tacatgggtg
181 tttcttattt taaaataatt tttctacttg aaatatttta caatacaata agggaaaaat
241 aaaaagttat ttaagttatt catactttct tcttcttttc ttttttgcta tagaaagtat
301 ttattttttc tggaacattt agaaaaaact tggatcccta tgaacagtgg agtgatcaag
361 aaatatggaa agttgcagat gaggtaaggc tgctaactga aatgattttg aaaggggtaa
421 ctcataccaa cacaaatggc tgatatagct gacatcattc tacacacttt gtgtgcatgt
481 atgtgtgtgc acaactttaa aatggagtac cctaacatac ctggagcaac aggtactttt
541 gactggacct acccctaact gaaatgattt tgaaagaggt aactcatacc aacacaaatg
601 gttgatatgg ctaagatcat tctacacact ttgtgtgcat gtatttctgt gcacaacttc
661 aaaatggagt accctaaaat acctggcgcg acaagtactt ttgactgagc ctactt
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA24 910 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 22.
ACCESSION M55129
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 24 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 910)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55128:384..>716,<1..535)
/number=21
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 536..708
/number=22
/gene="CFTR gene"
BASE COUNT 238 a 164 c 202 g 306 t
ORIGIN Map position 7q31-q32.
1 cacagttgac tattttatgc tatcttttgt cctcagtcat gacagagtag aagatgggag
61 gtagcaccaa ggatgatgtc atacctccat cctttatgct acattctatc ttctgtctac
121 ataagatgtc atactagagg gcatatctgc aatgtataca tattatcttt tccagcatgc
181 attcagttgt gttggaataa tttatgtaca cctttataaa cgctgagcct cacaagagcc
241 atgtgccacg tattgtttct tactactttt ggatacctgg cacgtaatag acactcattg
301 aaagtttcct aatgaatgaa gtacaaagat aaaacaagtt atagactgat tcttttgagc
361 tgtcaaggtt gtaaatagac ttttgctcaa tcaattcaaa tggtggcagg tagtgggggt
421 agagggattg gtatgaaaaa cataagcttt cagaactcct gtgtttattt ttagaatgtc
481 aactgcttga gtgtttttaa ctctgtggta tctgaactat cttctctaac tgcaggttgg
541 gctcagatct gtgatagaac agtttcctgg gaagcttgac tttgtccttg tggatggggg
601 ctgtgtccta agccatggcc acaagcagtt gatgtgcttg gctagatctg ttctcagtaa
661 ggcgaagatc ttgctgcttg atgaacccag tgctcatttg gatccagtgt gagtttcaga
721 tgttctgtta cttaatagca cagtgggaac agaatcatta tgcctgcttc atggtgacac
781 atatttctat taggctgtca tgtctgcgtg tgggggtctc ccaagatatg aaataattgc
841 ccagtggaaa tgagcataaa tgcatatttc cttgctaaga gttcttgtgt tttcttccga
901 agatagtttt
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA25 983 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 23.
ACCESSION M55130
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 25 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 983)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55129:709..>910,<1..288)
/number=22
/note="gap of unknown legnth"
/gene="CFTR gene"
exon 289..394
/number=23
/gene="CFTR gene"
BASE COUNT 316 a 163 c 174 g 330 t
ORIGIN Map position 7q31-q32.
1 gcatgtttat agccccaaat aaaagaagta ctggtgattc tacataatga aaatgtactc
61 atttattaaa gtttctttga aatatttgtc ctgtttattt atggatactt agagtctacc
121 ccatggttga aaagctgatt gtgcgtaacg ctatatcaac attatgtgaa aagaacttaa
181 agaaataagt aatttaaaga gataatagaa caatagacat attatcaagg taaatacaga
241 tcattactgt tctgtgatat tatgtgtggt attttctttc ttttctagaa cataccaaat
301 aattagaaga actctaaaac aagcatttgc tgattgcaca gtaattctct gtgaacacag
361 gatagaagca atgctggaat gccaacaatt tttggtgagt ctttataact ttacttaaga
421 tctcattgcc cttgtaattc ttgataacaa tctcacatgt gatagttcct gcaaattgca
481 acaatgtaca agttcttttc aaaaatatgt atcatacagc catccagctt tactcaaaat
541 agctgcacaa gtttttcact ttgatctgag ccatgtggtg aggttgaaat atagtaaatc
601 taaaatggca gcatattact aagttatgtt tataaatagg atatatatac ttttgagccc
661 tttatttggg accaagtcat acaaaatact ctactgttta agattttaaa aaaggtccct
721 gtgattcttt caataactaa atgtcccatg gatgtggtct ggacaggcct agttgtctta
781 cagtctgatt tatggtatta atgacaaagt tgagaggcac atttcatttt tctagccatg
841 atttgggttc aggtagtacc tttctcaacc accttctcac tgttcttaaa aaaactgtca
901 catggccagg cacagtggct tacatctgta atcccaatac tttgggaggc tgaggtgggg
961 ggattacttg aggccaggaa ttc
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS HUMCFTRA26 2106 bp ds-DNA PRI 14-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 24.
ACCESSION M55131
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 26 of 26
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2106)
AUTHORS Zielenski,J., Rozmahel,R., Bozon,D., Kerem,B.-S., Grzelczak,Z.,
Riordan,J.R., Rommens,J.M. and Tsui,L.-C.
TITLE Genomic DNA sequence of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene
JOURNAL Genomics 10, 214-228 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M55130:395..>983,<1..189)
/number=23
/note="gap of unknown legnth"
/gene="CFTR gene"
mRNA join(M55106:<829..881,M55107:251..361,M55108:185..293,
M55109:253..468,M55110:243..332,M55111:286..449,
M55111:1582..1707,M55112:240..486,M55113:336..428,
M55114:461..643,M55115:308..499,M55116:295..389,
M55117:284..370,M55118:177..900,M55119:349..477,
M55120:220..257,M55121:363..613,M55122:326..405,
M55123:213..363,M55124:156..383,M55125:335..435,
M55126:186..434,M55127:267..422,M55128:294..383,
M55129:536..708,M55130:289..394,190..>2106)
/gene="CFTR gene"
/partial
CDS join(M55106:829..881,M55107:251..361,M55108:185..293,
M55109:253..468,M55110:243..332,M55111:286..449,
M55111:1582..1707,M55112:240..486,M55113:336..428,
M55114:461..643,M55115:308..499,M55116:295..389,
M55117:284..370,M55118:177..900,M55119:349..477,
M55120:220..257,M55121:363..613,M55122:326..405,
M55123:213..363,M55124:156..383,M55125:335..435,
M55126:186..434,M55127:267..422,M55128:294..383,
M55129:536..708,M55130:289..394,190..390)
/product="cystic fibrosis transmembrane conductance
regulator"
/gene="CFTR gene"
/codon_start=829
exon 190..>2106
/number=24
/gene="CFTR gene"
BASE COUNT 629 a 411 c 439 g 627 t
ORIGIN Map position 7q31-q32.
1 agatggtaga acctccttag agcaaaagga cacagcagtt aaatgtgaca tacctgattg
61 ttcaaaatgc aaggctctgg acattgcatt ctttgacttt tattttcctt tgagcctgtg
121 ccagtttctg tccctgctct ggtctgacct gccttctgtc ccagatctca ctaacagcca
181 tttccctagg tcatagaaga gaacaaagtg cggcagtacg attccatcca gaaactgctg
241 aacgagagga gcctcttccg gcaagccatc agcccctccg acagggtgaa gctctttccc
301 caccggaact caagcaagtg caagtctaag ccccagattg ctgctctgaa agaggagaca
361 gaagaagagg tgcaagatac aaggctttag agagcagcat aaatgttgac atgggacatt
421 tgctcatgga attggagctc gtgggacagt cacctcatgg aattggagct cgtggaacag
481 ttacctctgc ctcagaaaac aaggatgaat taagtttttt tttaaaaaag aaacatttgg
541 taaggggaat tgaggacact gatatgggtc ttgataaatg gcttcctggc aatagtcaaa
601 ttgtgtgaaa ggtacttcaa atccttgaag atttaccact tgtgttttgc aagccagatt
661 ttcctgaaaa cccttgccat gtgctagtaa ttggaaaggc agctctaaat gtcaatcagc
721 ctagttgatc agcttattgt ctagtgaaac tcgttaattt gtagtgttgg agaagaactg
781 aaatcatact tcttagggtt atgattaagt aatgataact ggaactcagc ggtttatata
841 agcttgtatt cctttttctc tcctctcccc atgatgttta gaaacacaac tatattgttt
901 gctaagcatt ccaactatct catttccaag caagtattag aataccacag gaaccacaag
961 actgcacatc aaaatatgcc ccattcaaca tctagtgagc agtcaggaaa gagaacttcc
1021 agatcctgga aatcagggtt agtattgtcc aggtctacca aaaatctcaa tatttcagat
1081 aatcacaata catcccttac ctgggaaagg gctgttataa tctttcacag gggacaggat
1141 ggttccctta cctgggaaag ggctgttata atctttcaca ggggacagga tggttccctt
1201 gatgaagaag ttgatatgcc ttttcccaac tccagaaagt gacaagctca cagacctttg
1261 aactagagtt tagctggaaa agtatgttag tgcaaattgt cacaggacag cccttctttc
1321 cacagaagct ccaggtagag ggtgtgtaag tagataggcc atgggcactg tgggtagaca
1381 cacatgaagt ccaagcattt agatgtatag gttgatggtg gtatgttttc aggctagatg
1441 tatgtacttc atgctgtcta cactaagaga gaatgagaga cacactgaag aagcaccaat
1501 catgaattag ttttatatgc ttctgtttta taattttgtg aagcaaaatt ttttctctag
1561 gaaatattta ttttaataat gtttcaaaca tatattacaa tgctgtattt taaaagaatg
1621 attatgaatt acatttgtat aaaataattt ttatatttga aatattgact ttttatggca
1681 ctagtatttt tatgaaatat tatgttaaaa ctgggacagg ggagaaccta gggtgatatt
1741 aaccaggggc catgaatcac cttttggtct ggagggaagc cttggggctg atcgaggttg
1801 ttgcccacag ctgtatgatt cccagccaga cacagcctct tagatgcagt tctgaagaag
1861 atggtaccac cagtctgact gtttccatca agggtacact gccttctcaa ctccaaactg
1921 actcttaaga agactgcatt atatttatta ctgtaagaaa atatcacttg tcaataaaat
1981 ccatacattt gtgtgaaact ttgttgtttt cagatgcgtt cacttgtcat gtttcatcag
2041 tctctcactc caatttctaa gcttcatgga acatgaaaca cgaatctgtc ttttagatat
2101 agcctc
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRA1 164 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 4, 5' end.
ACCESSION M65273
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 164)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..154
/gene="CFTR gene"
BASE COUNT 52 a 25 c 26 g 61 t
ORIGIN
1 tgaaaatagt gctaagagtt tcacatatgg tatgaccctc tatataaact cattttaagt
61 ctcctctaaa gatgaaaagt cttgtgttga aattctcagg gtattttatg agaaataaat
121 gaaatttaat ttctctgttt ttcccctttt gtaggaagtc acca
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRA2 99 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 4.
ACCESSION M65274
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 99)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65273:155..>164,<1..11)
/number=4
/gene="CFTR gene"
/label=4
intron 12..>99
/gene="CFTR gene"
BASE COUNT 30 a 17 c 19 g 33 t
ORIGIN
1 tttataagaa ggtaatactt ccttgcacag gccccatggc acatatattc tgtatcgtac
61 atgttttaat gtcataaatt aggtagtgag ctggtacaa
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRB1 164 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 5, 5' end.
ACCESSION M65276
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 164)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..154
/gene="CFTR gene"
BASE COUNT 58 a 16 c 18 g 72 t
ORIGIN
1 gagaagatag taagctagat gaatagaata taattttcat tacctttact taataatgaa
61 tgcataataa ctgaattagt catattataa ttttacttat aatatatttg tattttgttt
121 gttgaaatta tctaactttc catttttctt ttagacttta aagc
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRB2 238 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 5.
ACCESSION M65277
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 238)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65276:155..>164,<1..11)
/number=5
/gene="CFTR gene"
/label=5
intron 12..>238
/gene="CFTR gene"
BASE COUNT 71 a 39 c 51 g 77 t
ORIGIN
1 aatttgatga agtatgtacc tattgattta atcttttagg cactattgtt ataaattata
61 caactggaaa ggcggagttt tcctgggtca gataatagta attagtggtt aagtcttgct
121 cagctctagc ttccctattc tggaaactaa gaaaggtcaa ttgtatagca gagcaccatt
181 ctggggtctg gtagaaggac ccaactcaaa ggcaccttag cctgttgtta ataagatt
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRC1 210 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 6a, 5' end.
ACCESSION M65278
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 210)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..200
/gene="CFTR gene"
BASE COUNT 52 a 35 c 41 g 82 t
ORIGIN
1 aaaaccgatt ctatgtgtag aatgtttaag cacattcgta tgtcgtccat gtaatgatta
61 cctagatttt agtgtgctca gaaccacgaa gtgtttgatc atataagctc cttttacttg
121 ctttctttca tatatgattg ttagtttcta ggggtggaag atacaatgac acctgttttt
181 gctgtgcttt tattttccag ggacttgcat
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRC2 250 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 6a.
ACCESSION M65279
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 250)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65278:201..>210,<1..9)
/number=6
/gene="CFTR gene"
/label=6a
intron 10..>250
/gene="CFTR gene"
BASE COUNT 67 a 55 c 44 g 84 t
ORIGIN
1 gaagtacagg tagcaaccta ttttcataac ttgaaagttt taaaaattat gttttcaaaa
61 agcccacttt agtaaaacca ggactgctct atgcatagaa cagtgatctt cagtgtcatt
121 aaattttttt tttttttttt tttttgagac agagtctaga tctgtcaccc aggctggagt
181 gcagtggcac gatcttggct cactgcactg caacttctgc ctcccaggct caagcaattc
241 tcctgcctca
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRD1 192 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 6b, 5' end.
ACCESSION M65280
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 192)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..182
/gene="CFTR gene"
BASE COUNT 66 a 23 c 32 g 71 t
ORIGIN
1 gtctggcaca taggaggcat ttaccaaaca gtagttatta tttttgttac catctatttg
61 ataataaaat aatgcccatc tgttgaataa aagaaatatg acttaaaacc ttgagcagtt
121 cttaatagat aatttgactt gtttttacta ttagattgat tgattgattg attgatttac
181 agagatcaga ga
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRD2 200 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 6b.
ACCESSION M65281
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 200)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65280:183..>192,<1..10)
/number=7
/gene="CFTR gene"
/label=6b
intron 11..>200
/gene="CFTR gene"
BASE COUNT 58 a 28 c 30 g 84 t
ORIGIN
1 acttaagaca gtaagttgtt ccaataattt caatattgtt agtaattctg tccttaattt
61 tttaaaaata tgtttatcat ggtagacttc cacctcatat ttgatgtttg tgacaatcaa
121 atgattgcat ttaagttctg tcaatattca tgcattagtt gcacaaattc actttcatgg
181 gctgtagttt tatgtagttg
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRE1 228 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 7, 5' end.
ACCESSION M65282
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 228)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..218
/gene="CFTR gene"
BASE COUNT 79 a 40 c 40 g 69 t
ORIGIN
1 acactggtac tttcattgtt atcttttcat ataaggtaac tgaggcccag agagattaaa
61 taacatgccc aaggtcacac aggtcatatg atgtggagcc aggttaaaaa tataggcaga
121 aagactctag agaccatgct cagatcttcc attccaagat ccctgatatt tgaaaaataa
181 aataacatcc tgaattttat tgttattgtt ttttatagaa cagaactg
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRE2 204 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 7.
ACCESSION M65283
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 204)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65282:219..228,<1..10)
/number=8
/gene="CFTR gene"
/label=7
intron 11..>204
/gene="CFTR gene"
BASE COUNT 78 a 32 c 31 g 63 t
ORIGIN
1 caaaatacag gtaatgtacc ataatgctgc attatatact atgatttaaa taatcagtca
61 atagatcagt tctaatgaac tttgcaaaaa tgtgcgaaaa gatagaaaaa gaaatttcct
121 tcactaggaa gttataaaag ttgccagcta atactaggaa tgttcacctt aaacttttcc
181 tagcatttct ctggacagta tgat
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRF1 169 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 8, 5' end.
ACCESSION M65284
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 169)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..158
/gene="CFTR gene"
BASE COUNT 66 a 16 c 18 g 69 t
ORIGIN
1 ttagaacact aataaaatta ttttattaag aaataattac tatttcatta ttaaaattca
61 tatataagat gtagcacaat gagagtataa agtagatgta ataatgcatt aatgctattc
121 tgattctata atatgttttt gctctctttt ataaatagga tttcttaca
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRF2 169 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 8.
ACCESSION M65285
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 169)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65284:159..>169,<1..10)
/number=9
/gene="CFTR gene"
/label=8
intron 11..>169
/gene="CFTR gene"
BASE COUNT 56 a 21 c 36 g 56 t
ORIGIN
1 ctgggaggag gtcagaattt ttaaaaaatt gtttgctcta aacacctaac tgttttcttc
61 tttgtgaata tggatttcat cctaatggcg aataaaatta gaatgatgat ataactggta
121 gaactggaag gaggatcact cacttatttt ctagattaag aagtagagg
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRG1 192 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, exon 9, 5' end.
ACCESSION M65286
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 1 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 192)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron <1..182
/gene="CFTR gene"
BASE COUNT 58 a 22 c 39 g 73 t
ORIGIN
1 ctagaaaccg tatgctatat aattatgtac tataaagtaa taatgtatac agtgtaatgg
61 atcatgggcc atgtgctttt caaactaatt gtacataaaa caagcatcta ttgaaaatat
121 ctgacaaact catcttttat ttttgatgtg tgtgtgtgtg tgtgtgtgtg tttttttaac
181 agggatttgg gg
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMCFTRG2 305 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human cystic fibrosis transmembrane conductance regulator (CFTR)
gene, partial exon 9.
ACCESSION M65288
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SEGMENT 2 of 2
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 305)
AUTHORS Gasparini,P., Nunes,V., Savoia,A., Dognini,M., Morral,N., Gaona,A.,
Bonizzato,A., Chillon,M., Sangiuolo,F., Novelli,G.,
Dallapiccola,B., Pignatti,P.F. and Estivill,X.
TITLE The search for south european cystic fibrosis mutations:
Identification of two new mutations, four variants, and intronic
sequences
JOURNAL Genomics 10, 193-200 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon order(M65286:183..>192,<1..10)
/number=10
/gene="CFTR gene"
/label=9
intron 11..>305
/gene="CFTR gene"
BASE COUNT 79 a 47 c 51 g 128 t
ORIGIN
1 agcaggcaag gtagttcttt tgttcttcac tattaagaac ttaatttggt gtccatgtct
61 cttttttttt ctagtttgta gtgctggaag gtatttttgg agaaattctt acatgagcat
121 taggagaatg tatgggtgta gtgtcttgta taatagaaat tgttccactg ataatttact
181 ctagtttttt atttcctcat attattttca gtggcttttt cttccacatc tttatatttt
241 gcaccacatt caacactgta tcttgcacat ggcgagcatt caataacttt attgaataaa
301 caaat
//