GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS XIPRKX 4170 bp ss-mRNA VRT 22-MAY-1991
DEFINITION Xiphophorus maculatus Xmrk oncogene DNA (X-chromosomal copy)
ACCESSION X56318
KEYWORDS Tyrosine kinase; Xmrk oncogene.
SOURCE Xiphophorus maculatus RNA.
ORGANISM Xiphophorus maculatus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Osteichthyes;
Actinopterygii; Atheriniformes; Cyprinodontoidei; Poeciliidae.
REFERENCE 1 (bases 1 to 4170)
AUTHORS Adam,D.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 4170)
AUTHORS Adam,D., Maeueler,W. and Schartl,M.
TITLE Transcriptional activation of the melanoma inducing Xmrk oncogene
in Xiphophorus
JOURNAL Oncogene 6, 73-80 (1991)
STANDARD full automatic
COMMENT From EMBL 26 entry XMRKX; dated 11-MAR-1991.
FEATURES Location/Qualifiers
mRNA join(77..232,321..396,1327..1473,1556..1653,1865..2002,
2384..4170)
/gene="Xmrk (X-chromosomal copy)"
CDS join(77..232,321..396,1327..1473,1556..1653,1865..2002,
2384..2704)
/partial
/product="Xmrk protein (X-chromosomal)"
/gene="Xmrk (X-chromosomal copy)"
/codon_start=77
exon 77..232
/number=1
/gene="Xmrk (X-chromosomal copy)"
exon 77..232
/gene="Xmrk (X-chromosomal copy)"
exon 77..232
/note="exon t"
/gene="Xmrk (X-chromosomal copy)"
intron 233..320
/number=1
exon 321..396
/number=2
/gene="Xmrk (X-chromosomal copy)"
exon 321..396
/gene="Xmrk (X-chromosomal copy)"
exon 321..396
/note="exon u"
/gene="Xmrk (X-chromosomal copy)"
intron 397..1326
/number=2
exon 1327..1473
/number=3
/gene="Xmrk (X-chromosomal copy)"
exon 1327..1473
/gene="Xmrk (X-chromosomal copy)"
exon 1327..1473
/note="exon v"
/gene="Xmrk (X-chromosomal copy)"
intron 1474..1555
/number=3
exon 1556..1653
/number=4
/gene="Xmrk (X-chromosomal copy)"
exon 1556..1653
/gene="Xmrk (X-chromosomal copy)"
exon 1556..1653
/note="exon w"
/gene="Xmrk (X-chromosomal copy)"
intron 1654..1864
/number=4
exon 1865..2002
/number=5
/gene="Xmrk (X-chromosomal copy)"
exon 1865..2002
/gene="Xmrk (X-chromosomal copy)"
exon 1865..2002
/note="exon x"
/gene="Xmrk (X-chromosomal copy)"
intron 2003..2383
/number=5
exon 2384..4170
/number=6
/gene="Xmrk (X-chromosomal copy)"
exon 2384..4170
/note="exon z"
/gene="Xmrk (X-chromosomal copy)"
polyA_signal 4165..4170
BASE COUNT 1171 a 920 c 900 g 1179 t
ORIGIN
1 gaattcaaat atttatttat ctatttagcg gttagttctg gtttgttaaa tgacacactg
61 tgtcctgctg gttcagggga tgaactacct ggaagagcgc cacctggtgc accgcgacct
121 ggcagccagg aacgtcctgc tgaaaaaccc gaaccacgtc aagatcacag acttcggtct
181 gtccaagctg ctgacggctg acgagaagga ataccaagcc gacggaggaa aggtgccatg
241 gcaatgcctg actggtttct gtttgctgtt cggactgaaa acatgtcaga gatgaatcac
301 tgctgcatct ctgtgagcag gttcccatta agtggatggc tttggagtcg atcctccagt
361 ggacctacac ccatcagagc gacgtgtgga gctacggtga ggaatcgtcc ccacagcgcc
421 acctacctgc cttcaccctc tgcttcctgt tagccggttt aaacatctga aaccgcacag
481 ccagaggatt tagactgaat aaaatacttc tacactatta gtgaatattg gttgcacatt
541 atcatctctt gttcaaaatg ttaaatgctt gagactcaaa ccagagtgag atttttgtac
601 actgaacaga tgctgaacat cagtgttagc atgtaaccct gattatattg atttattcct
661 gattatattt aatctgatca tggaaatctt accagttttc ctgtttgaaa ttagaatgag
721 tgatttgtat tactaaaaat taaaacttag ggctcttagt ttagctaaaa tcccatctta
781 cgttgaaagc acgtgacgtt catttatgga gctccagtag cagtcagtca agccacaaat
841 ctgaagaacc ctctgactgg agactgttgc accctaacag ctccacatcc aggcaccaga
901 aacattagta acatagcaac acatcctgga tgactccatc cgttagcata ctctgctaat
961 ccgcctcatt tgcttttgct gctcgtcttt aaacctctgg ttggctgtga ggtcagaaag
1021 atgttggagt aggggatatg atcgatggaa cttgaacttc ttccttctct ctctgctctc
1081 catccatgaa gcctcctttc tacctcatct gggatttggg gtcaaagttc aggtgatatt
1141 ttatctacct gaggtccaca aatcaggtag acgagtccgt tgacaggaca gctacgagtc
1201 attctaacta taaatggcta agtgtgttcc tgcagaaaat gagaaaattg ttctttttcc
1261 ttttgtgcgg tgttattgct aggctaggct aggctaacca agctaaagtc actcctgtct
1321 ctgcaggtgt gacggtttgg gagttgatga catttggatc caaaccgtac gacggcatcc
1381 cggccaagga gatcgcctcg gtgctggaga acggggagcg gctgccgcag cctcccatct
1441 gcaccatcga agtctacatg atcatcctga agtgtaagag ctgaccctgc aggtggcgct
1501 gcaggctggc tgggctgttt cctcatggta gtgtgttgtc cccgtctccc tgcaggctgg
1561 atgatcgacc cgtccagcag acccaggttc agagagctgg tgggcgagtt ctcccagatg
1621 gcccgggacc cgtccaggta cctggtcata caggtacgcc accgccccca cctgacccta
1681 ctataaaaca ctaacagaac aattctgggt tttcacttta cgtttcagaa aatatatcca
1741 aagagtccaa atcaaaatct aaatgttttt cattaagtaa ctgaacatta aaaagcgaat
1801 ctaatcaaat atggaataat aaagtgtatt tgactgtttt ggttgcctct gacttgtttc
1861 ccagggcaac ctgccgagtc tgtctgatcg gaggcttttc tcccgcctgc tgagctctga
1921 tgacgacgtg gtcgacgcgg atgaatacct gctgccatac aaatggataa accgccaggg
1981 cagcgagccc tgcatcccgc cggtaaaaac tctgatgcta accgaacagc aacctgaaac
2041 aagtcctgga gtttctggag ttttcattct gacctggaaa gtccgaggtt cctcaccggc
2101 tgggtctcag aatccaacat ggctgccgct catacagaca gctgtcaaga ttttcatttg
2161 aatttgtgtc tcaataatct gatccttata aaaccataag accagctaat aaaactgttg
2221 ccacaaaatt aaattacata aatcaggatt tctgagtagt ctgggaaaat ctggacttta
2281 acttcagtaa ctttccaggt ctggatcagc aaaaacaact acagtgtgga ggatgttgta
2341 tttgtaactg cttttccatt tggccatgtt ttatgttaac cagcctggga gtgaaaccag
2401 cagcaggctg tcggatatct acaatcccag ctacgaggac ctgacagacg gctggggccc
2461 ggtgtcgctg tcctcccagg aggcggagac caacttctcc agaccggagt acctgaacac
2521 caaccaaaac tcgctccccc tggtgtccag tggcagcatg gacgaccccg actaccaggc
2581 tggctaccag gctgccttcc taccgcagac tggagagctc actgggaacg gcatgttcct
2641 ccctgcagca gagaacctgg agtacctgga acagggaggc gcactgtaca ctcctgtccg
2701 ctagggggca gcagcgctcc gactgaagct gtggctttgc tcagataaac agtggtctgt
2761 tttaaattgg acagataact ggatttaact cagatggttc actgtcggtt ctccagagga
2821 actgaaacag aacaagaact tcctgttcct tcaggcaaag gtccaatctt tggctctaag
2881 ctgacgggat taacgcatct ggaaaatgaa cattacccag ataaactgta aaaacataag
2941 ctaattcagg ttacattaaa aaagactcgc tcagctctcc tgctctcaca tgtgggtttg
3001 gatgctgcag gacgatgcag atgttttaat cctgggcgct tctgtttcca acatttacat
3061 tcatgaactg aaaacattta agttttctga agatatgatt tgactgtcag tcaacatgat
3121 gtatgcaacc ttaaatcttt cagaataaga gaaaacaggt gaaactggat tctcaggcca
3181 cactgctcta ctccagatat ttataactgc cattttgtaa aaaaaaaaga atctgcattc
3241 acacaatctg ctggttttct atcagaacaa ttttatacaa gccttgcaag agcaggtgga
3301 aataaaatta agcttactaa aattgaaatt ttgtagaaga caacgttggg tgaacgaaat
3361 aacacaaatg gttctgtttt ataggttgta gaaggacaga ggaggacatg tccaccatgt
3421 tttttaatcc tctttggaca tcacgttccc acagatacat cagtgttttt aaaaatctca
3481 ccaaaatctg tgtgcatgtc gataggagac gtggagacga agtggaaaaa ttttaatttt
3541 actaaacatc agagttggtg gggagatttg aagagtttac taatttttta aagattattc
3601 agtaatctgg aataaggaac gcaattcagc taaacttcac ggaaccattt cagtccaaac
3661 tgtagcacaa ggagaacctc ctgttgttgt ctgacttgaa atattcactc ttgattgttt
3721 gtgttgttga atttttgaaa gaaagtttgc tttacttgac acaaatgagc caaaccctga
3781 cgtcctgctg ctgaatatta ctgctagtct ctgtttgtct ttaatgttta ttgattaaaa
3841 aaaaacaaag tgaagtttct gactgtggtt gctggttttt atacttagta tctataagat
3901 actatatata tatatatata tatatatata tatatatata tatatatata tataaacact
3961 aaaggtttac ataacattat ggtgaacaca taaatgattt aatttacctt tgagttcttt
4021 ctgaagtttc acatccagct taaatcctgt gtcgttgttg aagcttttaa ggacgtatga
4081 ataattctat aagcattatt aatattaata gctctgcagc gactgctaac atgttgcctg
4141 cacaccggaa gtgtctatgt gactaataaa
//GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS XIPRKY 5579 bp ss-mRNA VRT 22-MAY-1991
DEFINITION Xiphophorus maculatus Xmrk oncogene DNA (Y-chromosomal copy)
ACCESSION X56319
KEYWORDS Tyrosine kinase; Xmrk oncogene.
SOURCE Xiphophorus maculatus RNA.
ORGANISM Xiphophorus maculatus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Osteichthyes;
Actinopterygii; Atheriniformes; Cyprinodontoidei; Poeciliidae.
REFERENCE 1 (bases 1 to 5579)
AUTHORS Adam,D.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 5579)
AUTHORS Adam,D., Maeueler,W. and Schartl,M.
TITLE Transcriptional activation of the melanoma inducing Xmrk oncogene
in Xiphophorus
JOURNAL Oncogene 6, 73-80 (1991)
STANDARD full automatic
COMMENT From EMBL 26 entry XMRKY; dated 11-MAR-1991.
FEATURES Location/Qualifiers
mRNA join(77..232,321..396,1322..1468,1551..1648,1860..1997,
3516..3606,3764..5579)
/gene="Xmrk (Y-chromosomal copy)"
CDS join(77..232,321..396,1322..1468,1551..1648,1860..1997,
3516..3606,3764..4098)
/partial
/product="Xmrk protein (Y-chromosomal)"
/gene="Xmrk (Y-chromosomal copy)"
/codon_start=77
exon 77..232
/number=1
/gene="Xmrk (Y-chromosomal copy)"
exon 77..232
/gene="Xmrk (Y-chromosomal copy)"
exon 77..232
/note="exon t"
/gene="Xmrk (Y-chromosomal copy)"
intron 233..320
/number=1
exon 321..396
/number=2
/gene="Xmrk (Y-chromosomal copy)"
exon 321..396
/gene="Xmrk (Y-chromosomal copy)"
exon 321..396
/note="exon u"
/gene="Xmrk (Y-chromosomal copy)"
intron 397..1321
/number=2
exon 1322..1468
/number=3
/gene="Xmrk (Y-chromosomal copy)"
exon 1322..1468
/gene="Xmrk (Y-chromosomal copy)"
exon 1322..1468
/note="exon v"
/gene="Xmrk (Y-chromosomal copy)"
intron 1469..1550
/number=3
exon 1551..1648
/number=4
/gene="Xmrk (Y-chromosomal copy)"
exon 1551..1648
/gene="Xmrk (Y-chromosomal copy)"
exon 1551..1648
/note="exon w"
/gene="Xmrk (Y-chromosomal copy)"
intron 1649..1859
/number=4
exon 1860..1997
/number=5
/gene="Xmrk (Y-chromosomal copy)"
exon 1860..1997
/gene="Xmrk (Y-chromosomal copy)"
exon 1860..1997
/note="exon x"
/gene="Xmrk (Y-chromosomal copy)"
intron 1998..3515
/number=5
exon 3516..3606
/number=6
/gene="Xmrk (Y-chromosomal copy)"
exon 3516..3606
/gene="Xmrk (Y-chromosomal copy)"
exon 3516..3606
/note="exon y"
/gene="Xmrk (Y-chromosomal copy)"
intron 3607..3763
/number=6
exon 3764..5579
/number=7
/gene="Xmrk (Y-chromosomal copy)"
exon 3764..5579
/note="exon z"
/gene="Xmrk (Y-chromosomal copy)"
polyA_signal 5574..5579
BASE COUNT 1582 a 1199 c 1130 g 1668 t
ORIGIN
1 gaattcaaat atttatttat ctatttagcg gttagttctg gtttgttaaa tgacacactg
61 tgtcctgctg gttcagggga tgaactacct ggaagagcgc cacctggtgc accgcgacct
121 ggcagccagg aacgtcctgc tgaaaaaccc gaaccacgtc aagatcacag acttcggtct
181 gtccaagctg ctgacggctg acgagaagga ataccaagcc gacggaggaa aggtgccatg
241 gcaatgcctg actggtttct gtttgctctt cggactgaaa acatgtcaga gatgaatcac
301 tgctgcatct ctgtgagcag gttcccatta agtggatggc tttggagtcg atcctccagt
361 ggacctacac ccatcagagc gacgtgtgga gctacggtga ggaatcgtcc ccacagcgcc
421 acctacctgc cttcaccctc tgcttcctgt tagccggttt aaacatctga aaccgcacag
481 ccagaggatt tagactgaat aaaatacttc tacactatta gtgaatattg gttgcacatt
541 atcatctctt gttcaaaatg ttaaatgctt gagactcaaa ccagagtgag atttttgtac
601 actgaacaga tgctgaacat cagtgttagc atgtaaccct gattatattg atttattcct
661 gattatattt aatctgatca tggaaatctt accagttttc ctgtttgaaa ttagaatgag
721 tgatttgtat tactaaaaat taaaacttag ggctcttagt ttagctaaaa tcccatctta
781 cgttgaaagg acgtggcgtt catttatgga gctccagtag cagtcagtca agccacaaat
841 ctgaagaagc ctctgactgg agactgttgc agcttaacag ctccacatcc aggcaccaga
901 aacattagta acatagcaac acatcctgga tgactccatc cgttagcata ctctgctaat
961 ccgcctcatt tgcttttgct gctcgtcttt aaacctctgg ttggctgtga ggtcagaaag
1021 atgttggagt aggggatatg atcgatggaa cttgaacttc ttccttctct ctctgctctg
1081 catccatgaa gcctcctttc tacctcatct gggatttggg gtcaaagttc aggtgatatt
1141 ttatctacct gaggtccaca aatcaggtag acgagtccgt tgacaggaca gctacgagtc
1201 attctaacta taaatggcta agtgtgttcc tgcagaaaat gagaaaattg ttctttttcc
1261 ttttgtgcgg tgttattgct aggctaggct aaccaagcta aagtcactcc tgtctctgca
1321 ggtgtgacgg tttgggagtt gatgacattc ggatccaaac catacgacgg catcccggcc
1381 aaggagatcg cctcggtgct ggagaacggg gagcggctgc cgcagcctcc catctgcacc
1441 atcgaagtct acatgatcat cctgaagtgt aagagctgac cctgcaggtg gcgctgcagg
1501 ctggctgggc tgtttcctca tggtagtgtg ttgtccccgt ctccctgcag gctggatgat
1561 cgacccgtcc agcagaccca ggttcagaga gctggtgggc gagttctccc agatggcccg
1621 ggacccgtcc aggtacctgg tcatacaggt acgccactgc ccccacctga ccctactata
1681 aaacactaac agaacaattc tgggttttca ctttatgttt cagaaaatat atccaaagag
1741 ttcaaatcaa aatctaaatg tttttcatta agtaactgaa cattaaaaag cgaatctaat
1801 caaatatgga ataataaagt atatttgact gttttggttg cctctgactt gtttcccagg
1861 gcaacctgcc gagtctgtct gatcggaggc ttttctcccg cctgctgagc tctgatgacg
1921 acgtggtcga cgccgatgaa tacctgctgc catacaaacg gataaaccgc cagggcagcg
1981 agccctgcat cccgccggta aaaactctga tgctaaccga acagcaacct gaaacaagtc
2041 ctggagtttc tggagttttc attctgacct ggaaagtccg aggttcctca ccggctgggt
2101 ctcagaatcc aacatggctg ccgctcatac agacagctgt caagattttc atttgaattt
2161 gtgtctcaat aatctgatcc ttataaaacc ataagaccag ctaataaaac tgttgccaca
2221 aaattaaatt acataaatca ggatttctga gtagtctggg aaaatctgga ctttaacttc
2281 agtaactttc caggtctgga tcagcaaaaa caactaaagt gtggaggatg ttgtatttgt
2341 aactgctttt ccatttggcc atgtttcatg ttcttccttc tttcctgttc cttcttagta
2401 tacttccttg tgtccttcaa tccttcattg tcttcatgtc tcattgaata agggaaacga
2461 gaaactttta tttatttatt cctttgtccg tcattctttc atttgtactt ttgttttttc
2521 cttccttcct tcttctcctg tccttcctac cttccttaat tacttttctt gttccttctt
2581 tcaattcttt tcattgtctc ttgtttttgc agcttagata tttaaaacat tccatttatt
2641 cacatattta ccataaattt atcaacattt ggtgttttat attttaactg gttttcaaat
2701 ttacaatata gttggtgttg ggattttagc cgtagacagt aaagaagctc tctcacctga
2761 tgagtgtaga gcagtgaatc cgtctctcct taaagacatt tcccagttct tcctcacatc
2821 gtgtctttat gaaaccttca aaataaaaac agaagatttg gtgtcttact tctgtgaaag
2881 aatgacatat aaataatatt ctttgccact tgtgtaatat ttgctttgga ttgttataac
2941 acataatatt agaataatat atttataatt ataaataaaa ttgttttatt tctaagatag
3001 cgctcttgtg tcaaataatt tcaatcaacg ttagggaata attcaaactt tttgaaaatt
3061 tacaaaatct cagttatcct tcatagcgtg gactgaacac cggtgttaca tcaagcacta
3121 aagctaatat tagctggcat ttcatggtgg acataaatac aataaaaata ttctaattat
3181 aaaatataaa caataatatg ttcatcttac ttgtgaaacg ttatcccctg agatctcatg
3241 gaaatagtcc gtcgatctca acaaaaatat ccggcagtgc tgagtcttct tctgctgttt
3301 tggtttagcc aagtaggagg aacgacggct ccaagatggc cgccgtattt cctgtgcagc
3361 caatgcgggg tttactcttt actatgtcta tgatgttaac acacatgtcc tgctactgcc
3421 aaccaccagg gggcagaaca atacgtaaag tgaaataatg ggcatgtttt atccaacatg
3481 gacactgatc catctgaact gtgtgtgttt tttagaatgg acatccagtg agagagaaca
3541 gcatcactct ccggaacatc tccgacccga cccagaacgc gctggagaaa gacctggatg
3601 gtcacggtag gttctgacca gcaatcactt tcttcaagaa atcaggaagt gatcacaata
3661 atggagtcaa acagacagga tacgagtcag atgcaaacaa ggagtttcac catagcaacc
3721 gagtccaggc tctaaataaa tcttcctgat gtttgtgttc cagagtacgt taaccagcct
3781 gggagtgaaa ccagcagcag gctgtcggat atctacaatc ccaactacga ggacctgaca
3841 gacggctggg gccccgtgtc gctgtcctcc caggaggcgg agaccaactt cgccagacca
3901 gagtacctga acaccaacca aaactcgctc cccctggtgt ccagtggcag catggacgac
3961 cccgactacc aggccggcta ccaggctgcc ttcctaccgc agactggagc gctcactggg
4021 aacggcatgt tcctccctgc agcagagaac ctggagtacc tgggacaggg aggcgcactg
4081 tacactcctg tccgctaggg ggcagcagcg ctccgactga agctgtggct ttgctcagat
4141 aaacggtggt ctgttttaaa ttggacagat aactggattt aactcagatg gttcactgtc
4201 ggttctccag aggaactgaa acagaacaag aacttcctgt tccttcaggc aaaggtccaa
4261 tctttggctc taagctgacg ggatgaacgc atctggaaaa tgaacattac ccagataaac
4321 tgtaaaaaca taagctaatt caggttacat taaaaaagac tcgctcaact ctcctgctct
4381 cacatgtggg tttggatgct gcaggacgat gcagatgttt taatcctggg cgcttctgtt
4441 tccaacattt acattcatga actgaaaaca tttaagtttt ctgaagatat gatttgactg
4501 tcagtcaaca tgatgtatgc aaccttaaat ctttcagaat aagagaaaac aggtgaaact
4561 ggattctcag gccacactgc tctactccag atatttataa ctgccatttt gtaataaaaa
4621 aaagaatctg cattcacaca atctgttggt tttctatcag aacaatttta tacaagcctt
4681 gcaagagcag gtggaaataa aattaagctt actaaaattg aaattttgta gaagacaacg
4741 ttgggtgaac gaaataacac aaatggttcc gttttatagg ttgtagaagg acagaggagg
4801 acatgtccac catgtttttt aatcctcttt ggacatcacg ttcccacaga tacatcagtg
4861 tttttaaaaa tctcaccaaa atctgtgtgc atgtcgacag gagacgtgga gatgaagtgg
4921 aaaaatttta attttactaa acatcagagt tggtggggag atttgaagag tttactaatt
4981 ttttaaagat tattcagtaa tctggaataa ggaacgcaat tcagctaaac ttcacggaac
5041 catttcagtc caaactgtag cacaaggaga acctcctgtt gttgtctgac ttgaaatatt
5101 cactcttgat tgtttgtgtt gttgaatttt tgaaagaaag tttgctttac ttgacacaaa
5161 tgagccaaac cctgacgtcc tgctgctgaa tattactgct agtctctgtt tgtctttaat
5221 gtttattgat taaaaaaaaa caaagtgaag tttctgactg tggttgctgg tttttatact
5281 tagtatctat aagatactat atatatatat atatatatat atatatatat atatatatat
5341 atatatatat atatatatat aaaaacacta aaggtttaca taacattatg gtgaacacat
5401 aaatgattta atttaccttt gagttctttc tgaagtttca catccagctt aaatcctgtg
5461 tcgttgttga agcttttaag gacgtatgaa taattctata agcattatta atattaatag
5521 ctctgcagcg actgctaaca tgttgcctgc acaccggaag tgtctatgtg actaataaa
//