GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS RABIG08 765 bp ds-DNA MAM 22-MAY-1991 DEFINITION Rabbit germline gene V19a for immunoglobulin kappa light chain variable region ACCESSION X02337 KEYWORDS immunoglobulin; immunoglobulin light chain; kappa-immunoglobulin; signal peptide; variable region. SOURCE Oryctolagus cuniculus DNA. ORGANISM Oryctolagus cuniculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Lagomorpha; Leporidae. REFERENCE 1 (bases 1 to 765) AUTHORS Heidmann,O. and Rougeon,F. TITLE Immunoglobulin kappa light-chain diversity in rabbit is based on the 3' length heterogeneity of germ-line variable genes JOURNAL Nature 311, 74-76 (1984) STANDARD full automatic COMMENT From EMBL 26 entry OCIG08; dated 07-NOV-1985. FEATURES Location/Qualifiers misc_feature 37..40 /note="put. CAAT-like sequence" misc_feature 74..78 /note="put. TATA-like sequence" misc_feature 101..103 /note="inframe initiation codon" mRNA 131..185 /note="exon 1" CDS 131..185 /note="signal peptide (aa -22 to -5) (185 is 1st base in codon)" /codon_start=131 intron 186..308 /note="intron I" mRNA 309..613 /note="exon 2" CDS 309..319 /note="signal peptide (aa -4 to -1) (309 is 2nd base in codon)" /codon_start=309 misc_feature 320..388 /note="FR1 (aa 1-23)" CDS 320..613 /note="V19a (aa 1-98)" /codon_start=320 misc_feature 389..421 /note="CDR1 (aa 24-24)" misc_feature 422..466 /note="FR2 (aa 35-49)" misc_feature 467..487 /note="CDR2 (aa 50-56)" misc_feature 488..583 /note="FR3 (aa 57-88)" misc_feature 584..613 /note="CDR3 (aa 89-98)" misc_feature 616..622 /note="recombination signal" misc_feature 635..643 /note="recombination signal" BASE COUNT 153 a 228 c 218 g 166 t ORIGIN 1 ggcccttcag ctgcacagcc ctgccacgcc cctgctcatt gcactgtccc tagagcagcc 61 cacctctctg ggcatttagg gcccaggctg ctcccgcccc atgcaggagg cagtgcaggc 121 aggacccagc atggacacga gggcccccac tcagctgctg gggctcctgc tgctctggct 181 cccaggtaag gaaggccagc agcaggaacg gcctcgggca gtgtgtccag ggctgcccgt 241 ctctgcagga gtgtcctctt agaatgtgag gatgagtgtg gtctctgtgt ttctgtttcc 301 ctcgtcaggt gccacttttg cccaagtgct gacccagact ccagcctccg tgtctgcagc 361 tgtgggaggc acagtcacca tcaattgcca ggccagtgag agcattagta gctacttaaa 421 ctggtatcag cagaaactag ggcagcctcc caaactcctg atctattatg catccactct 481 ggcatctggg gtcccatcgc ggttcaaagg cagtggatct gggacagagt acactcttac 541 catcagcggt gtgcagtgtg acgatgctgc cacttactac tgtcagcatg gttatattta 601 tagtagtggt gataccacag tgttccaagc cctaacaaaa accccccagg aaagcagaag 661 tgtgaggctg ggctgcccca gctgctcctc cttgggcccc atctgctgag agtgattctc 721 agagcagcca ggcttgaagg tcctgcaggg tcgggtggaa ggggc //