GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS MUSIGVH76 700 bp ds-DNA ROD 22-MAY-1991
DEFINITION Mouse rearranged immunoglobulin V(H)76 segment promoter region
ACCESSION X53776
KEYWORDS Immunoglobulin heavy chain; immunoglobulin;
immunoglobulin V-segment.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 700)
AUTHORS Gearhart,P.J.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 700)
AUTHORS Lebecque,S.G. and Gearhart,P.J.
TITLE Boundaries of Somatic Mutation in Rearranged Immunoglobulin Genes:
5' Boundary Is Near the Promoter, and 3' Boundary Is ~ 1kb from
V(D)J Gene
JOURNAL J. Exp. Med. 172, 1717-1727 (1990)
STANDARD full automatic
COMMENT DNA from V(H) family 7183
From EMBL 26 entry MMIGVH76; dated 27-MAR-1991.
FEATURES Location/Qualifiers
mRNA join(<537..582,690..>700)
/note="for V(H)76 segment"
sig_peptide join(537..582,690..700)
/note="for V(H)76 segment"
CDS join(537..582,690..700)
/partial
/product="V(H)76 segment leader peptide"
/codon_start=537
TATA_signal 429..435
exon 537..582
/number=1
exon 537..582
exon 537..582
/note="for V(H)76 leader peptide"
exon 690..700
/number=2
exon 690..700
exon 690..700
/note="for V(H)76 leader peptide"
BASE COUNT 216 a 140 c 145 g 199 t
ORIGIN
1 ctgagtgctc ccatcacgga gatgaatctg ctatgaacag ctcataggtg tgagcctcta
61 caaaagccat attattgaaa agccacattg tgcccagact ttggaaagac tgagctcata
121 tcctgaaata cagttatgtg tggttctatt taattacaca tttacactaa ggaaacatgg
181 cagtatggga atgaagcttg ttctgtacac attaacagag ggaaactaaa caaagtatgg
241 tgaatcccta accaaaagtt aaaaaaaaaa aagaaaaaga aagaaaaaag tgaactacaa
301 tatgtttcaa tgctgtactg aatctggttt tgatgcctta tatctggtat catcagtgac
361 ttcagattga gtccaactcc agagcatggt atagcaggaa gacatgcaaa tgagtcttct
421 ctctgcccat gaaaaacacc ttggccctga ccctgcagct ctgacagagg aggcctgtcc
481 tggattcgat tcccagttcc tcacattcag tcagcactga acacggaccc ctcaccatga
541 acttcgggct cagcttgatt ttccttgtcc ttgttttaaa aggtaattta ttgagaagtg
601 atgacatctg ttgtatgcac atgagacaga gaaaaattgt tgtttgtttt gttagtgaga
661 gttttccaac cagtattctc tgtttgcagg tgtccagtgt
//