GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMENKB5 1831 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human preproenkephalin B gene 5' region and exon 1
ACCESSION X02536 J00122 X00174
KEYWORDS enkephalin; tandem repeat.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1014)
AUTHORS Noda,M., Teranishi,Y., Takahashi,H., Toyosato,M., Notake,M.,
Nakanishi,S. and Numa,S.
TITLE Isolation and structural organization of the human preproenkephalin
gene
JOURNAL Nature 297, 431-434 (1982)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1831)
AUTHORS Horikawa,S., Takai,T., Toyosato,M., Takahashi,H., Noda,M.,
Kakidani,H., Kubo,T., Hirose,T., Inayama,S., Hayashida,H.,
Miyata,T. and Numa,S.
TITLE Isolation and structural organization of the human preproenkephalin
B gene
JOURNAL Nature 306, 611-614 (1983)
STANDARD full automatic
COMMENT SWISS-PROT; P01213; NDDB$HUMAN.
Data kindly reviewed (04-MAR-1986) by M. Noda
From EMBL 26 entry HSENKB1; dated 28-MAR-1991.
FEATURES Location/Qualifiers
misc_feature 207..274
/note="tandem repeat"
misc_feature 275..342
/note="tandem repeat"
misc_feature 343..410
/note="tandem repeat"
promoter 422..430
/note="put. CAAT-box"
promoter 457..466
/note="put. TATA-box"
precursor_RNA 491..>1831
/note="put. primary transcript"
mRNA 491..1806
/note="exon 1"
misc_RNA 491..491
/note="put. cap-site"
intron 1807..>1831
/note="intron I"
BASE COUNT 388 a 505 c 454 g 484 t
ORIGIN
1 acagatgagc aatcagaggt tgaagttggc agcttatcca aggtctctcc gatggtgagt
61 ggcagacctg agagtcaaac tcacatctta aatgtcatta agcacagcct gtgtatggag
121 aggctgagtc ccagagaaga aaactgaccc cacccctcag tgtgggcaga ttcaagcctg
181 gggagaggca agggaggggg cagaaacttg gagggtagat ggacctgact ttaggttcta
241 gctggatgac ttacttgctg tgtgtctcta ggaacttgga gggtagatgg acctgacttt
301 aggttctagc tggatgactt acttgctgtg tgtctctagg aacttggagg atagatggac
361 ctgactttag gttctagctg gatgacttac ttgctgtgtg tctctaggaa agtttctcag
421 ctctcaaacc tctgttttct catctgcaag atggggataa tattaaccaa ctggctaggt
481 catgaggatt aaatctgaca actctaccta accgcctggt gcagccaggt gcccacaaaa
541 tgggcggccc tgccagactt ctgaaatagt tgtgcctccc accacaaact gtctgctatt
601 gactgagaag agaagcatgt tctcttccaa actcaaagac ccttatgttc tggaagatct
661 ctgtagcaat gaagagtgcc accttcaagc tgctgctggt ccaggccaag ggtatattga
721 ggtgggtcca tccctcaccc agagtgtgtg ctgaggcata ttgcagccca tattttgagg
781 ggtttttcct gctattcatt ttgtgttgcc gccagagaaa actaaactgc agctcctggc
841 tgtcggggaa gagctgtgct tctgccaggg ctagtgtgcc tggcaccagc tcaggcatgt
901 accagagccg aatgccgttt gcaggcaaat gtacacacaa aaagattcca gcacacgcgt
961 gcaccagcca acacagagtt gccacggcac gcaacagcgg gccatgcacg tgcctgctga
1021 ctcggctgtc atcttccgac tctcttccgt gatcagaaga ctgtctcagc ctctgtctgt
1081 ctccacgtct gtctgtctgt ggatcagtgt gttttgagtc tgacagtcta cctggctggt
1141 ttcctttttt cttgctctgt ccctctctcc ttgtgtttct acccatctcc ctatctctgc
1201 cactctctgt ctctgttttt ctttctcttt ctcccctcct ttgtatcact ccctaggtcc
1261 gacattgcct ctttctcgat ttccgattct ctctgagtct ctctctctct ctctctttct
1321 ctaactcttc tgtctctgtc cttccctgtc ttctttttcc tgtgacactc tcctggaaac
1381 gcatcaaaaa ctgaagtggc cggatttcaa gtgacaaaca gcactacacc cagaatccgc
1441 cccctcccca acacggctgc cttcctcctc cacatccctg tcacgaagag aagcctattg
1501 tgtcaggccc agggagttcg agttgaaggg cctgggggtc tgtgctctga ctgctctcag
1561 ccacttcccc attggctccc agcagcctgt gctcagcaag ggctgagcga caggggaggc
1621 tctcgtccat aaaagggggg aagaggcacc agaactgcca tttgaagggg ctttggtggt
1681 gttcacagct gcctctttgg cacctcctcc caagccggag tcaaggaggc ccctgagcct
1741 tggaccagcc actgccacct ccgacctgct cggccagaag ctgcccaggg acaaagcaga
1801 gtgcaggtaa catccagagg gggcactgga a
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