GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMGCRBR 3791 bp ss-mRNA PRI 22-MAY-1991
DEFINITION Human mRNA for beta-glucocorticoid receptor (clone OB10)
ACCESSION X03348 M11050
KEYWORDS glucocorticoid receptor.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3791)
AUTHORS Hollenberg,S.M., Weinberger,C., Ong,E.S., Cerelli,G., Oro,A.,
Lebo,R., Thompson,E.B., Rosenfeld,M.G. and Evans,R.M.
TITLE Primary structure and expression of a functional human
glucocorticoid receptor cDNA
JOURNAL Nature 318, 635-641 (1985)
STANDARD full automatic
COMMENT From EMBL 26 entry HSGCRBR; dated 28-MAR-1991.
FEATURES Location/Qualifiers
CDS 133..2358
/note="(aa 1-742)"
/product="beta-glucocorticoid receptor"
/codon_start=133
misc_feature 3168..3173
/note="pot. polyA signal"
misc_feature 3539..3545
/note="pot. polyA signal"
misc_feature 3770..3775
/note="put. polyA signal"
polyA_site 3791..3791
BASE COUNT 1162 a 759 c 808 g 1062 t
ORIGIN
1 tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa gctaagttgt
61 ttatctcggc tgcggcggga actgcggacg gtggcgggcg agcggctcct ctgccagagt
121 tgatattcac tgatggactc caaagaatca ttaactcctg gtagagaaga aaaccccagc
181 agtgtgcttg ctcaggagag gggagatgtg atggacttct ataaaaccct aagaggagga
241 gctactgtga aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc
301 aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc gcagcagcca
361 gatctgtcca aagcagtttc actctcaatg ggactgtata tgggagagac agaaacaaaa
421 gtgatgggaa atgacctggg attcccacag cagggccaaa tcagcctttc ctcgggggaa
481 acagacttaa agcttttgga agaaagcatt gcaaacctca ataggtcgac cagtgttcca
541 gagaacccca agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt
601 ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca gactggcacc
661 aacggtggca atgtgaaatt gtataccaca gaccaaagca cctttgacat tttgcaggat
721 ttggagtttt cttctgggtc cccaggtaaa gagacgaatg agagtccttg gagatcagac
781 ctgttgatag atgaaaactg tttgctttct cctctggcgg gagaagacga ttcattcctt
841 ttggaaggaa actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa
901 attaaggata atggagatct ggttttgtca agccccagta atgtaacact gccccaagtg
961 aaaacagaaa aagaagattt catcgaactc tgcacccctg gggtaattaa gcaagagaaa
1021 ctgggcacag tttactgtca ggcaagcttt cctggagcaa atataattgg taataaaatg
1081 tctgccattt ctgttcatgg tgtgagtacc tctggaggac agatgtacca ctatgacatg
1141 aatacagcat ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca
1201 attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga caacttgact
1261 tctctgggga ctctgaactt ccctggtcga acagtttttt ctaatggcta ttcaagcccc
1321 agcatgagac cagatgtaag ctctcctcca tccagctcct caacagcaac aacaggacca
1381 cctcccaaac tctgcctggt gtgctctgat gaagcttcag gatgtcatta tggagtctta
1441 acttgtggaa gctgtaaagt tttcttcaaa agagcagtgg aaggacagca caattaccta
1501 tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg cccagcatgc
1561 cgctatcgaa aatgtcttca ggctggaatg aacctggaag ctcgaaaaac aaagaaaaaa
1621 ataaaaggaa ttcagcaggc cactacagga gtctcacaag aaacctctga aaatcctggt
1681 aacaaaacaa tagttcctgc aacgttacca caactcaccc ctaccctggt gtcactgttg
1741 gaggttattg aacctgaagt gttatatgca ggatatgata gctctgttcc agactcaact
1801 tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc agcagtgaaa
1861 tgggcaaagg caataccagg tttcaggaac ttacacctgg atgaccaaat gaccctactg
1921 cagtactcct ggatgtttct tatggcattt gctctggggt ggagatcata tagacaatca
1981 agtgcaaacc tgctgtgttt tgctcctgat ctgattatta atgagcagag aatgactcta
2041 ccctgcatgt acgaccaatg taaacacatg ctgtatgttt cctctgagtt acacaggctt
2101 caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc ttcagttcct
2161 aaggacggtc tgaagagcca agagctattt gatgaaatta gaatgaccta catcaaagag
2221 ctaggaaaag ccattgtcaa gagggaagga aactccagcc agaactggca gcggttttat
2281 caactgacaa aactcttgga ttctatgcat gaaaatgtta tgtggttaaa accagaaagc
2341 acatctcaca cattaatctg attttcatcc caacaatctt ggcgctcaaa aaatagaact
2401 caatgagaaa aagaagatta tgtgcacttc gttgtcaata ataagtcaac tgatgctcat
2461 cgacaactat aggaggcttt tcattaaatg ggaaaagaag ctgtgccctt ttaggatacg
2521 tgggggaaaa gaaagtcatc ttaattatgt ttaattgtgg atttaagtgc tatatggtgg
2581 tgctgtttga aagcagattt atttcctatg tatgtgttat ctggccatcc caacccaaac
2641 tgttgaagtt tgtagtaact tcagtgagag ttggttactc acaacaaatc ctgaaaagta
2701 tttttagtgt ttgtaggtat tctgtgggat actatacaag cagaactgag gcacttagga
2761 cataacactt ttggggtata tatatccaaa tgcctaaaac tatgggagga aaccttggcc
2821 accccaaaag gaaaactaac atgatttgtg tctatgaagt gctggataat tagcatggga
2881 tgagctctgg gcatgccatg aaggaaagcc acgctccctt cagaattcag aggcagggag
2941 caattccagt ttcacctaag tctcataatt ttagttccct tttaaaaacc ctgaaaacta
3001 catcaccatg gaatgaaaaa tattgttata caatacattg atctgtcaaa cttccagaac
3061 catggtagcc ttcagtgaga tttccatctt ggctggtcac tccctgactg tagctgtagg
3121 tgaatgtgtt tttgtgtgtg tgtgtctggt tttagtgtca gaagggaaat aaaagtgtaa
3181 ggaggacact ttaaaccctt tgggtggagt ttcgtaattt cccagactat tttcaagcaa
3241 cctggtccac ccaggattag tgaccaggtt ttcaggaaag gatttgcttc tctctagaaa
3301 atgtctgaaa ggattttatt ttctgatgaa aggctgtatg aaaataccct cctcaaataa
3361 cttgcttaac tacatataga ttcaagtgtg tcaatattct attttgtata ttaaatgcta
3421 tataatgggg acaaatctat attatactgt gtatggcatt attaagaagc tttttcatta
3481 ttttttatca cagtaatttt aaaatgtgta aaaattaaaa ccagtgactc ctgtttaaaa
3541 ataaaagttg tagtttttta ttcatgctga ataataatct gtagttaaaa aaaaagtgtc
3601 tttttaccta cgcagtgaaa tgtcagactg taaaaccttg tgtggaaatg tttaactttt
3661 attttttcat ttaaatttgc tgttctggta ttaccaaacc acacatttgt accgaattgg
3721 cagtaaatgt tagccattta cagcaatgcc aaatatggag aaacatcata ataaaaaaat
3781 ctgctttttt c
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