GenBank-Updates@genbank.bio.net (05/22/91)
LOCUS HUMIGF1G1 3021 bp ds-DNA PRI 22-MAY-1991
DEFINITION Human gene for insulin-like growth factor I
ACCESSION X03563
KEYWORDS growth factor; hormone; insulin super family;
insulin-like growth factor I; somatomedin.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3021)
AUTHORS Dull,T.J., Gray,A., Hayflick,J.S. and Ullrich,A.
TITLE Insulin-like growth factor II precursor gene organization in
relation to insulin gene family
JOURNAL Nature 310, 777-781 (1984)
STANDARD full automatic
COMMENT SWISS-PROT; P01343; IGFA$HUMAN. SWISS-PROT; P05019; IGFB$HUMAN.
Data kindly reviewed (24-OCT-1986) by A. Ullrich
From EMBL 26 entry HSIGF1G1; dated 28-MAR-1991.
FEATURES Location/Qualifiers
misc_feature 685..686
/note="pot. exon-intron splice site"
misc_feature 781..782
/note="pot. exon-intron splice site"
CDS 782..943
/note="(exon 1) (aa -27 to 27"
/product="pot. IGF-I precursor"
/gene="IGF-I"
/codon_start=782
mat_peptide 863..943
/product="pot. IGF-I precursor"
misc_feature 938..939
/note="pot. exon-intron splice site"
misc_feature 942..943
/note="pot. exon-intron splice site"
BASE COUNT 856 a 614 c 600 g 949 t 2 others
ORIGIN
1 gccagggact ttagaataca ggagtggttt ctatttgagc caatttcatt cttcgattct
61 catatttttt tctgtttctg ttattttctt ctatttgtgg ttgtgtcaac tgctgatatg
121 ccccaggtaa ggaatcagtc tctctctctc tctctctctc tctctctctc tcatattgag
181 gaaacaaaac aaaaacaaac cctgtgatga tatatagtat tgtcaaaagc cattttttgg
241 ccatagtaaa ttatttttag tcaaaaatag ggaatgatgt tttggttaaa aatattctgc
301 tcaataatga atgcatatac catctatgga tggccaatat tgagagaatt taaattaaca
361 aaacttattt ggccccaaat ctgtactgag cacaatttaa cctttgataa ttcaaaagtt
421 ctaccagggt ctcagagtga tatgggatcc cactgtaata atagcatctt tcatttccgt
481 agtaaacgtt tctagatatt ttgtctcaat tcattgaaat aggaacccta aagaaagggt
541 tcagggagga ctcctccaaa gatccacagt agccagggga ataaacacag gttgttggat
601 gccgagacac gctccatcca caactccctc tgggttctca tgtactctat tggcttctgt
661 gctgggtagt cctgattaat gacagtcgtg gaatcgtggg agtcaatgca cttctgtccc
721 accccactcc ccttgcaagg atcaaggagg aaacctgacc ctccctctgt ttcttgggca
781 ggtgaagatg cacaccatgt cctcctcgca tctcttctac ctggcgctgt gcctgctcac
841 cttcaccagc tctgccacgg ctggaccgga gacgctctgc ggggctgagc tggtggatgc
901 tcttcagttc gtgtgtggag acaggggctt ttatttcagt aagtagccct ccctctcaat
961 gtgctgctca agtctaaagt gtacagctct gtggatttac aaccgcaggg agtgtgtgaa
1021 taactgaatg agtgcccgta tctggcagcc atcctaggcc tctgagattc ctcaccttaa
1081 agtaagcata gtgttttggc gggactttgg caggttttgc agatctagga tggaattttc
1141 ctccttaaca attcgtcttt aactacttcc tgctaagcct tctttcaact attatgatcc
1201 acctcactat tccattcctt tcaatgaaag gacaggacaa aataaccctg aggtattgat
1261 gtttttgttt tcaaaaccta tgggcgcaca tataaacata tggaacacat gcagggctgc
1321 tttaagtgct atgtgatttg gagtaaaata gtaaggactc tccagtcatg tggatctggg
1381 aaaaaaaata ttaaagggca tatcctagat gtctccattc aatatgaaat caccatgaac
1441 agacagaagg ttaactcccc ttaaaggcag gcctgtttgc aaatacacag actgtctcta
1501 aatgcaaact gaaatgccat actgatttgc cctctatgcc gcttgacctt gatttttttg
1561 ttgttgctct cttttggcat agttcttacn ccggacccat caatgatatc accatctgga
1621 aaagggtctc tgacaagtac agaatcactt atctcttaaa tagctcttag gtgattagaa
1681 agtcaacagc cagtaaaaag tagacagcca agtcaaggcg tataaataat acacacaagc
1741 aaaagtcaat gattcctgtg ggaactgatc acttaaagaa tctagctccc atgcatctat
1801 ctcactgtat attataggac agagaaagat ttaaagccag atgcttgttc cttataattc
1861 tttggagttt tagagagttc caggaaactg agcatgagtc attcttaaag gttcatatca
1921 ctccagtgta gacagcttac ctcagttacc cactatgctt tgaatagctc cgtgatgact
1981 cacacacttg aagtctctct catccttccc aaatgtcagc ctctctccag gcaggtgggg
2041 tatgtgtgtg tatgactggc agggtagagg gtggcctgtg tataccagtc tggagatcag
2101 taagggagat gggaagaaag aggcttgtga gggtattggc gatcagtact tacagtggat
2161 ttggcaacaa atagttttta aatcactagt gacaaagaat cagaagtgcc ttctactatt
2221 tgaataggca aattcccact atttgcttcc agccagtcct ttaattgaac gaactcattt
2281 atttttctgg caataaagca attctatcca gttctctgtt gcagagcaga tgaatgagtg
2341 cattgggtga gtgattttcc aatagcagac ttgttttacc tttaaaatat cctgtggaag
2401 ataactgtgg gacatcacat gatccaacag tgggtcataa ttattctata atttgcagct
2461 actgatcctc attttttaaa gaaatgaaaa agtggttctc acttattatg cccaagggga
2521 cttttttttt ccttgataat ccatttgtgc aatttccttt gatccagttc actaggtaat
2581 tgccaagcct agaagtgtcc tctgttacgt gccaggttga attgtgatgt tcaaccgaca
2641 ttgctccaga atttccatgc acagtgcatg aaaactggat ctttctatgc ctatgatgtt
2701 tgcattaaat gatgaaaaat gagaatggaa aaaatgattg ttcctaagta actgtatgat
2761 acttataagt gtttgcacag acacttaagg atattggaca actaaaatgg aaaccaattt
2821 ccangttctc ttattctgtt actgcaacaa tcaaatttca gcaaattttt aaaaattgta
2881 tctcaataac ttgaaaagga aatgttatat atagcaaatc ttgattctta ctatatgact
2941 ttagctagaa agtggctttg taaatcatat gttcttgtca gtattgtcat tgaaaatatg
3001 tgtgtcatga gttttgcctt a
//