GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMIGHAT 375 bp ss-mRNA PRI 23-MAY-1991
DEFINITION Human Ig rearranged mu heavy chain mRNA V-region (VH26-D-J) from
B-cell hybridoma cell line 18/2.
ACCESSION M17746
KEYWORDS diversity region; immunoglobulin; immunoglobulin heavy chain;
joining region; mu-immunoglobulin; processed gene; variable region;
variable region subgroup VH-III.
SOURCE Human (systemic lupus erythematosus patient) B-cell hybridoma 18/2
cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 375)
AUTHORS Dersimonian,H., Schwartz,R.S., Barrett,K.J. and Stollar,B.D.
TITLE Relationship of human variable region heavy chain germ-line genes
to genes encoding anti-DNA autoantibodies
JOURNAL J. Immunol. 139, 2496-2501 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable copy of sequence in [1] kindly
provided by Dr.B.David Stollar.
FEATURES Location/Qualifiers
CDS <1..>375
/note="Ig H-chain V-region (VH26-D-J; AA at 1)
/hgml_locus_uid='LK0080M' /nomgen='IGHV' /map='14q32.33'"
misc_recomb 294^295
/note="VH26 end/D-region start"
misc_recomb 342^343
/note="D-region end/J-region start (JH4 or JH5)"
BASE COUNT 77 a 94 c 121 g 83 t
ORIGIN Chromosome 14.
1 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc
61 tcctgtgcag cctctggatt cacctttagc agctatgcca tgagctgggt ccgccaggct
121 ccagggaagg ggctggagtg ggtctcagct attagtggta gtggtggtag cacatactac
181 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgctgtat
241 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaaagggcaa
301 gtgttgtact atggttcggg gagttatcac tggttcgacc cctggggcca gggaaccctg
361 gtcaccgtct cctca
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMIGHAU 375 bp ss-mRNA PRI 23-MAY-1991
DEFINITION Human Ig rearranged mu heavy chain mRNA V-region (VH26-D-J) from
B-cell hybridoma cell line 18/17.
ACCESSION M17747
KEYWORDS diversity region; immunoglobulin; immunoglobulin heavy chain;
joining region; mu-immunoglobulin; processed gene; variable region;
variable region subgroup VH-III.
SOURCE Human (systemic lupus erthematosus patient) B-cell hybridoma cell
line 18/17 cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 375)
AUTHORS Dersimonian,H., Schwartz,R.S., Barrett,K.J. and Stollar,B.D.
TITLE Relationship of human variable region heavy chain germ-line genes
to genes encoding anti-DNA autoantibodies
JOURNAL J. Immunol. 139, 2496-2501 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable copy of sequence in [1] kindly
provided by Dr.B.David Stollar.
FEATURES Location/Qualifiers
CDS <1..>375
/note="Ig H-chain V-region (VH26-D-J; AA at 1)
/hgml_locus_uid='LK0080M' /nomgen='IGHV' /map='14q32.33'"
misc_recomb 294^295
/note="VH26 end/D-region start"
misc_recomb 342^343
/note="D-region end/J-region start (JH4 or JH5)"
BASE COUNT 77 a 94 c 121 g 83 t
ORIGIN Chromosome 14.
1 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc
61 tcctgtgcag cctctggatt cacctttagc agctatgcca tgagctgggt ccgccaggct
121 ccagggaagg ggctggagtg ggtctcagct attagtggta gtggtggtag cacatactac
181 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgctgtat
241 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaaagggcaa
301 gtgttgtact atggttcggg gagttatcac tggttcgacc cctggggcca gggaaccctg
361 gtcaccgtct cctca
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMIGHAV 375 bp ss-mRNA PRI 23-MAY-1991
DEFINITION Human Ig rearranged mu heavy chain mRNA V-region (VH26) from B-cell
hybridoma cell line 18/9.
ACCESSION M17748
KEYWORDS diversity region; immunoglobulin; immunoglobulin heavy chain;
joining region; mu-immunoglobulin; processed gene; variable region;
variable region subgroup VH-III.
SOURCE Human B-cell hybridoma cell line 18/9.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 375)
AUTHORS Dersimonian,H., Schwartz,R.S., Barrett,K.J. and Stollar,B.D.
TITLE Relationship of human variable region heavy chain germ-line genes
to genes encoding anti-DNA autoantibodies
JOURNAL J. Immunol. 139, 2496-2501 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable copy of sequence in [1] kindly
provided by Dr.B.David Stollar.
FEATURES Location/Qualifiers
CDS <1..>375
/note="Ig H chain V-region (VH26-D-J; AA at 1)
/hgml_locus_uid='LK0080M' /nomgen='IGHV' /map='14q32.33'"
misc_recomb 294^295
/note="VH26-end/D-region start"
misc_recomb 342^343
/note="D-region end/J-region start (JH4 or JH5)"
BASE COUNT 77 a 94 c 121 g 83 t
ORIGIN Chromosome 14.
1 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc
61 tcctgtgcag cctctggatt cacctttagc agctatgcca tgagctgggt ccgccaggct
121 ccagggaagg ggctggagtg ggtctcagct attagtggta gtggtggtag cacatactac
181 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgctgtat
241 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaaagggcaa
301 gtgttgtact atggttcggg gagttatcac tggttcgacc cctggggcca gggaaccctg
361 gtcaccgtct cctca
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMIGHAW 375 bp ss-mRNA PRI 23-MAY-1991
DEFINITION Human Ig rearranged mu heavy chain mRNA V-region (VH26-D-J), from
B-cell hybridoma cell line 18/9.
ACCESSION M17749
KEYWORDS diversity region; immunoglobulin; immunoglobulin heavy chain;
joining region; mu-immunoglobulin; processed gene; variable region;
variable region subgroup VH-III.
SOURCE Human B-cell hybridoma 1/17 cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 375)
AUTHORS Dersimonian,H., Schwartz,R.S., Barrett,K.J. and Stollar,B.D.
TITLE Relationship of human variable region heavy chain germ-line genes
to genes encoding anti-DNA autoantibodies
JOURNAL J. Immunol. 139, 2496-2501 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable copy of sequence in [1] kindly
provided by Dr.B.David Stollar.
FEATURES Location/Qualifiers
CDS <1..>375
/note="Ig heavy chain V-region (VH26-D-J; AA at 1)
/hgml_locus_uid='LK0080M' /nomgen='IGHV' /map='14q32.33'"
misc_recomb 294^295
/note="VH26 end/D-region start"
misc_recomb 342^343
/note="D-region end/J-region start (JH4 or JH5)"
BASE COUNT 77 a 94 c 121 g 83 t
ORIGIN Chromosome 14.
1 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc
61 tcctgtgcag cctctggatt cacctttagc agctatgcca tggagctggg tccgccaggc
121 tccagggaag gggctggagt ggtctcagct attagtggta gtggtggtag cacatactac
181 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgctgtat
241 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaaagggcaa
301 gtgttgtact atggttcggg gagttatcac tggttcgacc cctggggcca gggaaccctg
361 gtcaccgtct cctca
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMIGHAX 357 bp ss-mRNA PRI 23-MAY-1991
DEFINITION Human Ig rearranged mu heavy chain mRNA V-region (V-D-J) from
B-cell hybridoma cell line 21/28.
ACCESSION M17750
KEYWORDS diversity region; immunoglobulin; immunoglobulin heavy chain;
joining region; mu-immunoglobulin; processed gene; variable region;
variable region subgroup VH-I.
SOURCE Human (systemic lupus erthematosus patient) B-cell hybridoma 21/28
cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 357)
AUTHORS Dersimonian,H., Schwartz,R.S., Barrett,K.J. and Stollar,B.D.
TITLE Relationship of human variable region heavy chain germ-line genes
to genes encoding anti-DNA autoantibodies
JOURNAL J. Immunol. 139, 2496-2501 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable copy of sequence in [1] kindly
provided by Dr.B.David Stollar.
FEATURES Location/Qualifiers
CDS <1..>357
/note="Ig heavy chain V-region (V-D-J; AA at 1)
/hgml_locus_uid='LK0080M' /nomgen='IGHV' /map='14q32.33'"
misc_recomb 294^295
/note="V-region end/D-region start"
misc_recomb 324^325
/note="D-region end/J-region start"
BASE COUNT 86 a 86 c 112 g 73 t
ORIGIN Chromosome 14.
1 caggtgcagc ttgtgcagtc tggggctgag gtgaagaagc ctggggcctc agtgaaggtt
61 tcctgcaagg cttctggata caccttcact agctatgcta tgcattgggt gcgccaggcc
121 cccggacaaa ggcttgagtg gatgggatgg atcaacgctg gcaatggtaa cacaaaatat
181 tcacagaagt tccagggcag agtcaccatt accagggaca catccgcgag cacagcctac
241 atggagctga gcagcctgag atctgaagac acggctgtgt attactgtgc gagaggaggt
301 tactatggtt cggggagcaa ctactggggc gagggaaccc tggtcaccgt ctcctca
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMIGHAY 369 bp ss-mRNA PRI 23-MAY-1991
DEFINITION Human Ig rearranged mu heavy chain mRNA V-region (V-D-J) from
B-cell hybridoma cell line 8E10.
ACCESSION M17751
KEYWORDS diversity region; immunoglobulin; immunoglobulin heavy chain;
joining region; mu-immunoglobulin; processed gene;
systemic lupus erythematosus; variable region;
variable region subgroup VH-I.
SOURCE Human (leprosy patient) B-cell hybridoma cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 369)
AUTHORS Dersimonian,H., Schwartz,R.S., Barrett,K.J. and Stollar,B.D.
TITLE Relationship of human variable region heavy chain germ-line genes
to genes encoding anti-DNA autoantibodies
JOURNAL J. Immunol. 139, 2496-2501 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable copy of sequence in [1] kindly
provided by Dr.B.David Stollar.
FEATURES Location/Qualifiers
CDS <1..>369
/note="Ig heavy chain V-region (V-D-J; AA at 1)
/hgml_locus_uid='LK0080M' /nomgen='IGHV' /map='14q32.33'"
misc_recomb 294^295
/note="V-region end/D-region start"
misc_recomb 324^325
/note="D-region end/J-region start"
BASE COUNT 86 a 97 c 113 g 73 t
ORIGIN Chromosome 14.
1 caggtgcagc ttgtgcagtc tggggctgag gtgaagaagc ctggggcctc agtgaaggtt
61 tcctgcaagg cttctggata caccttcact agctatgcta tgcattgggt gcgccaggcc
121 cccggacaaa ggcttgagtg gatgggatgg atcaacgctg gcaatggtaa cacaaaatat
181 tcacagaagt tccagggcag agtcaccatt accagggaca catccgcgag cacagcctac
241 atggagctga gcagcctgag atctgaagac acggctgtgt attactgtgc gagggccatg
301 atcctccgga tcgggcatgg tcagccccag ggctactggg gccaaggaac cctggtcacc
361 gtctcctca
//