GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMTCBVD 800 bp ds-DNA PRI 23-MAY-1991
DEFINITION Human T-cell receptor germline beta chain gene V-region (V)
V-beta-MT1-1.
ACCESSION M11955
KEYWORDS T-cell receptor; T-cell receptor beta-chain; germline;
variable region.
SOURCE Adult T-cell leukemia cell line MT-1 DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 800)
AUTHORS Ikuta,K., Ogura,T., Shimizu,A. and Honjo,T.
TITLE Low frequency of somatic mutation in beta-chain variable region
genes of human T-cell receptors
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 82, 7701-7705 (1985)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon <47..107
/note="T-cell receptor V-region (V), exon 1 /nomgen='TCRB'
/map='7q32 or 7q35' /hgml_locus_uid='LP0151Q'"
CDS join(47..107,413..715)
/partial
/note="T-cell receptor V-region (V)"
/codon_start=47
intron 108..412
/note="TCRB intron A"
exon 413..>715
/note="T-cell receptor V-region (V), exon 2"
iDNA 716..800
/note="V-D intervening DNA (5' end +/- 1 bp)"
BASE COUNT 171 a 210 c 245 g 174 t
ORIGIN Chromosome 7.
1 ggtcacaact ctccccagag aaggtggtgt gaggccatca cggaagatgc tgctgcttct
61 gctgcttctg gggccaggta taagcctcct tctacctggg agcttgggtg ggcatgtgcg
121 tgtgttggca tggtcaagtg gtggccagca gggttgcaat gtggattgtt tatgctcatc
181 gaagggagag ggagaggccc tgctctctag aggtgtaaat ggtaaggtga aagccgccgg
241 tcagaggaga tgggggatta tggccctagg gagatgacgg gaagattgca caaaacaaac
301 aggactctcc aggagctggg agcacaggga gggagtgagg ctcagctctg cctggcgtcc
361 tgtctgactc ggctcccact gggctctcct ctctctctgg cttctgtctc agcaggctcc
421 gggcttggtg ctgtcgtctc tcaacatccg agctgggtta tctgtaagag tggaacctct
481 gtgaagatcg agtgccgttc cctggacttt caggccacaa ctatgttttg gtatcgtcag
541 ttcccgaaac agagtctcat gctgatggca acttccaatg agggctccaa ggccacatac
601 gagcaaggcg tcgagaagga caagtttctc atcaaccatg caagcctgac cttgtccact
661 ctgacagtga ccagtgccca tcctgaagac agcagcttct acatctgcag tgctagagac
721 acagcgccag gaggggatca gacaccgcgg caagaacctg cagctgccct ccgccccagc
781 gggccccctg agtgctgaga
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMTCBVR 600 bp ds-DNA PRI 23-MAY-1991
DEFINITION Human T-cell receptor germline beta chain gene V-region (V)
V-beta-ATL12-2.
ACCESSION M11953
KEYWORDS T-cell receptor; T-cell receptor beta-chain; germline;
variable region.
SOURCE Human adult T-cell leukemia cell line ATL-12-2.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 600)
AUTHORS Ikuta,K., Ogura,T., Shimizu,A. and Honjo,T.
TITLE Low frequency of somatic mutation in beta-chain variable region
genes of human T-cell receptors
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 82, 7701-7705 (1985)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon <21..69
/note="T-cell receptor beta-chain V-region (V), exon 1
/nomgen='TCRB' /map='7q32 or 7q35'
/hgml_locus_uid='LP0151Q'"
CDS join(21..69,207..503)
/partial
/note="T-cell receptor beta-chain V-region (V)"
/codon_start=21
intron 70..206
/note="TCRB intron A"
exon 207..>503
/note="T-cell receptor beta-chain V-region (V), exon 2"
iDNA 504..>600
/note="V-D intervening DNA (5' end +/- 1 bp)"
BASE COUNT 125 a 158 c 150 g 167 t
ORIGIN Chromosome 7.
1 catcctggcc tgaccctgcc atgggcacca ggctcctctg ctgggtggtc ctgggtttcc
61 tagggacagg tgagtcctca gaacaccaag tagtttcatt ttttctgttt gtaggtgtgt
121 gtgtgtgaga gagtggttgt gtgtgtgtgt gtgtatgatg actacaaata ttttccttat
181 tctgttgcca aattctattt ccacagatca cacaggtgct ggagtctccc agtcccctag
241 gtacaaagtc gcaaagagag gacaggatgt agctctcagg tgtgatccaa tttcgggtca
301 tgtatccctt ttttggtacc aacaggccct ggggcagggg ccagagtttc tgacttattt
361 ccagaatgaa gctcaactag acaaatcggg gctgcccagt gatcgcttct ttgcagaaag
421 gcctgaggga tccgtctcca ctctgaagat ccagcgcaca cagcaggagg actccgccgt
481 gtatctctgt gccagcagct tagccacagc atggcacagt tgcctccttc ctgttcacaa
541 acctcatcct tctctctcct tgcagctcct agagacccta aacagaggcc tctctttgct
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMTCBVS 600 bp ds-DNA PRI 23-MAY-1991
DEFINITION Human T-cell receptor germline beta chain gene V-region (V)
V-beta-ATL2-1.
ACCESSION M11951
KEYWORDS T-cell receptor; T-cell receptor beta-chain; germline;
variable region.
SOURCE Human adult T-cell leukemia cell line ATL2 DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 600)
AUTHORS Ikuta,K., Ogura,T., Shimizu,A. and Honjo,T.
TITLE Low frequency of somatic mutation in beta-chain variable region
genes of human T-cell receptors
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 82, 7701-7705 (1985)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon <1..49
/note="T-cell receptor beta-chain V-region (V), exon 1
/nomgen='TCRB' /map='7q32 or 7q35'
/hgml_locus_uid='LP0151Q'"
CDS join(1..49,181..472)
/partial
/note="T-cell receptor beta-chain V-region (V)"
/codon_start=1
intron 50..180
/note="TCRB intron A"
exon 181..>472
/note="T-cell receptor beta-chain V-region (V), exon 2"
iDNA 473..>600
/note="V-D intervening DNA"
BASE COUNT 147 a 134 c 147 g 172 t
ORIGIN Chromosome 7.
1 atggcctccc tgctcttctt ctgtggggcc ttttatctcc tgggaacagg tgagtttgga
61 acacagatgg ggaaatcact gccttaaatt ttccaggttc tgaattaagc ctatcctcag
121 agattgcagc acgaggatat ttaccagttt ctgtcttcaa tttctgtctt atttccacag
181 ggtccatgga tgctgatgtt acccagaccc caaggaatag gatcacaaag acaggaaaga
241 ggattatgct ggaatgttct cagactaagg gtcatgatag aatgtactgg tatcgacaag
301 acccaggact gggcctacgg ttgatctatt actcctttga tgtcaaagat ataaacaaag
361 gagagatctc tgatggatac agtgtctctc gacaggcaca ggctaaattc tccctgtccc
421 tagagtctgc catccccaac cagacagctc tttacttctg tgccaccagt gatttgcaca
481 gtgcttcttg gccacctgct ctctacacag aaagacagac acatgggtga gttgtttgct
541 ctgaagggta cctggatgtg ggttgtggga tgtggggtgt ttagagcttt cagtggtctt
//