GenBank-Updates@genbank.bio.net (02/28/91)
LOCUS MUSIGHXO2 366 bp ds-DNA ROD 28-FEB-1991
DEFINITION Mouse Ig active gamma-1-chain gene V-region (VDJ) from hybridoma
B6.2.
ACCESSION M19659 M12821 M59074
KEYWORDS diversity exon; gamma-immunoglobulin; immunoglobulin;
immunoglobulin heavy chain; joining exon; processed gene; variable
exon; variable region.
SEGMENT 2 of 2
SOURCE Mouse hybridoma cell line B6.2 DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 366)
AUTHORS Sahagan,B.G., Dorai,H., Saltzgaber-Muller,J., Toneguzzo,F.,
Guindon,C.A., Lilly,S.P., McDonald,K.W., Morrissey,D.V.,
Stone,B.A., Davis,G.L., McIntosh,P.K. and Moore,G.P.
TITLE A genetically engineered murine/human chimeric antibody retains
specificity for human tumor-associated antigen
JOURNAL J. Immunol. 137, 1066-1074 (1986)
STANDARD simple staff_review
REFERENCE 2 (bases 1 to 366)
AUTHORS Sahagan,B.G.
TITLE Correction: A genetically engineered murine/human chimeric antibody
retains specificity for human tumor-associated antigen
JOURNAL J. Immunol. 145, 3150-3150 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS join(M19998:1..46,1..366)
/note="Ig gamma-1-chain V-region (VDJ) precursor"
sig_peptide join(M19998:1..46,1..11)
/note="Ig gamma-1-chain signal peptide"
sig_peptide 1..11
/note="Ig gamma-1-chain signal peptide"
exon 1..>366
/partial
/note="Ig gamma-1-chain V-region (VDJ) precursor"
mat_peptide 12..>366
/partial
/note="Ig gamma-1-chain"
BASE COUNT 86 a 99 c 86 g 95 t
ORIGIN Chromosome 12.
1 atgtcttgtc ccaagttact ctaaaagagt ctggccctgg gatattgaag ccctcacaga
61 ccctcagtct gacttgttct ttctctgggt tttcactgag cacttctggt atgggtgtag
121 gctggattcg tcagccttca ggaaagagtc tggagtggct ggcacacatt tggtggaatg
181 atgagaggta ctataaccca tccctgaaga accagctcac aatctccaag gatacctcca
241 gaaaccaggt attcctcaag atcaccagtg tggacactgc agatactgcc acttactact
301 gtgctcgatc ccctaggggg tactttgact actggggcca cggcaccact ctcacagtct
361 cctcag
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS MUSIGHXO2 366 bp ds-DNA ROD 23-MAY-1991
DEFINITION Mouse Ig active gamma-1-chain gene V-region (VDJ) from hybridoma
B6.2.
ACCESSION M19659 M12821 M59074
KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin;
immunoglobulin heavy chain; joining region; processed gene;
variable region.
SEGMENT 2 of 2
SOURCE Mouse hybridoma cell line B6.2 DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 366)
AUTHORS Sahagan,B.G., Dorai,H., Saltzgaber-Muller,J., Toneguzzo,F.,
Guindon,C.A., Lilly,S.P., McDonald,K.W., Morrissey,D.V.,
Stone,B.A., Davis,G.L., McIntosh,P.K. and Moore,G.P.
TITLE A genetically engineered murine/human chimeric antibody retains
specificity for human tumor-associated antigen
JOURNAL J. Immunol. 137, 1066-1074 (1986)
STANDARD simple staff_review
REFERENCE 2 (bases 1 to 366)
AUTHORS Sahagan,B.G.
TITLE Correction: A genetically engineered murine/human chimeric antibody
retains specificity for human tumor-associated antigen
JOURNAL J. Immunol. 145, 3150-3150 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS join(M19998:1..46,1..366)
/note="Ig gamma-1-chain V-region (VDJ) precursor"
sig_peptide join(M19998:1..46,1..11)
/note="Ig gamma-1-chain signal peptide"
sig_peptide 1..11
/note="Ig gamma-1-chain signal peptide"
exon 1..>366
/partial
/note="Ig gamma-1-chain V-region (VDJ) precursor"
mat_peptide 12..>366
/partial
/note="Ig gamma-1-chain"
BASE COUNT 86 a 99 c 86 g 95 t
ORIGIN Chromosome 12.
1 atgtcttgtc ccaagttact ctaaaagagt ctggccctgg gatattgaag ccctcacaga
61 ccctcagtct gacttgttct ttctctgggt tttcactgag cacttctggt atgggtgtag
121 gctggattcg tcagccttca ggaaagagtc tggagtggct ggcacacatt tggtggaatg
181 atgagaggta ctataaccca tccctgaaga accagctcac aatctccaag gatacctcca
241 gaaaccaggt attcctcaag atcaccagtg tggacactgc agatactgcc acttactact
301 gtgctcgatc ccctaggggg tactttgact actggggcca cggcaccact ctcacagtct
361 cctcag
//