GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS MUSIGKWG1 525 bp ds-DNA ROD 23-MAY-1991
DEFINITION Mouse Ig rearranged kappa chain 25-47 gene V-region (V-J) from
hybridoma, exon 1.
ACCESSION M24497 M18773
KEYWORDS immunoglobulin; immunoglobulin light-chain; joining region;
kapa-immunoglobulin; processed gene; variable region.
SEGMENT 1 of 2
SOURCE Mouse anti-streptococcal group A carbohydrate hybridoma DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 525)
AUTHORS Lutz,C.T. and Davie,J.M.
TITLE Genetics and primary structure of V-kappa gene segments encoding
antibody to streptococcal group A carbohydrate: Comparison of
V-kappa gene structure with idiotope expression
JOURNAL J. Immunol. 140, 641-645 (1988)
STANDARD simple staff_review
FEATURES Location/Qualifiers
exon 246..294
/note="Ig kappa chain V-region (V-J) precursor, exon 1"
sig_peptide 246..294
/note="Ig kappa signal peptide"
intron 295..>525
/note="Ig kappa chain intron A"
BASE COUNT 137 a 99 c 122 g 167 t
ORIGIN Chromosome 6.
1 gaattcatct gccctaatat tggcagtgag gactgagtta gttttctaca aacatggaat
61 gaactttgtc aagtaactct tgagagtggg attttttaac tctctaggta ctttttacac
121 agctctatca accaggagat ttgcatattg ctccctaggg aggacctctt cttgcaggtg
181 cagggtaaaa gctcactcct ctttctgtct tgattacttt tgactcacca tatcaagttc
241 gcagaatgag gttctctgct cagcttctgg ggctgcttgt gctctggatc cctggtaagg
301 agacaaagat gaagaaggag aattttgagg gagggggatt tctgagacat gatgataaat
361 atgtatgttc tgtacatgtc tgagatatac agttctgttc tccagtaaag gacttgtgag
421 gttcaaagtg tgaagagatt aaggtctgtt tttctgtgac aactctgaca gttccaaagc
481 caaaagtcaa atgctagaga ctctctgtgc ttcctctaca tgcat
//GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS MUSIGKWG2 310 bp ds-DNA ROD 23-MAY-1991
DEFINITION Mouse Ig rearranged kappa chain 25-47 gene V-region (V-J) from
hybridoma, exon 2.
ACCESSION M24498 M18773
KEYWORDS immunoglobulin; immunoglobulin light-chain; joining region;
kapa-immunoglobulin; processed gene; variable region.
SEGMENT 2 of 2
SOURCE Mouse anti-streptococcal group A carbohydrate hybridoma DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 310)
AUTHORS Lutz,C.T. and Davie,J.M.
TITLE Genetics and primary structure of V-kappa gene segments encoding
antibody to streptococcal group A carbohydrate: Comparison of
V-kappa gene structure with idiotope expression
JOURNAL J. Immunol. 140, 641-645 (1988)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS join(M24497:246..294,1..310)
/note="Ig kappa chain V-region (V-J) precursor"
sig_peptide join(M24497:246..294,1..11)
/note="Ig kappa signal peptide"
sig_peptide 1..11
/note="Ig kappa signal peptide"
exon 1..>310
/partial
/note="Ig kappa chain V-region (V-J) precursor, exon 2"
mat_peptide 12..>310
/partial
/note="Ig kappa chain V-region (V-J) VK-25-47"
BASE COUNT 77 a 75 c 72 g 86 t
ORIGIN About 130 bp after segment 1; chromosome 6.
1 gatccactgc agatattgtg atgacgcagg ctgcattctc caatccagtc actcttggaa
61 catcagcttc catctcctgc aggtctagta agagtctcct acatagtaat ggcatcactt
121 atttgtattg gtatctgcag aagccaggcc agtctcctca gctcctgatt tatcagatgt
181 ccaaccttgc ctcaggagtc ccagacaggt tcagtagcag tgggtcagga actgatttca
241 cactgagaat cagcagagtg gaggctgagg atgtgggtgt ttattactgt gctcaaaatc
301 tagaacttcc
//