GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HS6U1102 21858 bp ds-DNA VRL 23-MAY-1991 DEFINITION Human herpesvirus 6 major capsid protein, alkaline exonuclease, and phosphotransferase genes, complete cds.; and 14 open reading frames, complete cds. ACCESSION M28243 KEYWORDS exonuclease; major capsid protein; phosphotransferase. SOURCE Human herpesvirus 6 (strain U1102; Downing isolate), [from human peripheral blood lymphocytes], clone pUC13. ORGANISM Human herpesvirus type 6 Viridae; ds-DNA enveloped viruses; Herpesviridae; Alphaherpesvirinae. REFERENCE 1 (bases 1 to 21858) AUTHORS Lawrence,G.L., Chee,M., Craxton,M.A., Gompels,U.A., Honess,R.W. and Barrell,B.G. TITLE Human herpesvirus 6 is closely related to human cytomegalovirus JOURNAL J. Virol. 64, 287-299 (1990) STANDARD full staff_review COMMENT Draft entry and computer-readable sequence for [1] kindly submitted by G.L.Lawrence, 22-SEP-1989. FEATURES Location/Qualifiers CDS <1..361 /note="ORF 0R (AA at 2)" /codon_start=2 CDS join(complement(16108..16980),complement(11782..12909)) /note="unidentified spliced gene" /codon_start=16980 CDS complement(545..1921) /note="ORF 1L" /codon_start=1921 TATA_signal complement(1972..1978) /note="putative" CDS complement(1999..3297) /note="ORF 2L" /codon_start=3297 TATA_signal complement(3324..3330) /note="putative" CDS complement(3477..4367) /note="ORF 3L" /codon_start=4367 CDS complement(4369..8406) /note="major capsid protein (ORF 4L)" /codon_start=8406 TATA_signal 8352..8359 /note="putative" CDS 8418..10736 /note="ORF 5R" /codon_start=8418 TATA_signal complement(8444..8450) /note="putative" TATA_signal complement(8495..8501) /note="putative" TATA_signal 10673..10680 /note="putative" CDS 10733..11785 /note="ORF 6R" /codon_start=10733 exon complement(11782..12909) /note="unidentified spliced gene, exon 2 (ORF 7L)" TATA_signal 12856..12862 /note="putative" CDS 12921..13178 /note="ORF 8R" /codon_start=12921 TATA_signal 13099..13105 /note="putative" CDS 13126..13776 /note="ORF 9R" /codon_start=13126 TATA_signal 13524..13530 /note="putative" TATA_signal 13542..13548 /note="putative" CDS 13754..15082 /note="ORF 10R" /codon_start=13754 CDS 15039..16046 /note="ORF 11R" /codon_start=15039 exon complement(16108..16980) /note="unidentified spliced gene, exon 1 (ORF 12L)" TATA_signal 16849..16855 /note="putative" TATA_signal 16944..16950 /note="putative" CDS 16952..18013 /note="ORF 13R" /codon_start=16952 TATA_signal complement(17140..17146) /note="putative" TATA_signal 17861..17867 /note="putative" CDS 18013..18357 /note="ORF 14R" /codon_start=18013 TATA_signal 18318..18324 /note="putative" CDS 18360..20048 /note="phosphotransferase (put.; ORF 15R)" /codon_start=18360 TATA_signal 20016..20022 /note="putative" CDS 20056..21522 /note="alkaline exonuclease (ORF 16R)" /codon_start=20056 TATA_signal 21398..21404 /note="putative" CDS 21459..21692 /note="ORF 17R" /codon_start=21459 BASE COUNT 5993 a 3748 c 5212 g 6905 t ORIGIN 1 gggagatccg gaatacacaa aaaaaaggag gcgccataga gttgacaacg acgacgataa 61 ggagatggct cgagaaaaga acgatttgag agaattggtg gatatgatag gaatgttaag 121 acaagagatt agtgcgttga agcatgttcg cgctcaatcg ccgcagagac atatcgttcc 181 gatggagact ctgcctacga tcgaggagaa aggcgccgcg tccccaaagc catctatttt 241 aaacgcttct ttggcgcctg aaaccgtaaa taggagcctt gctggtcaga acgaatccac 301 ggatctgctg aaactcaaca agaaattgtt tgttgacgcg ttaaataaaa tggatagtta 361 aaatgtattt ttatgttgtg atcaagtggt gtttagctgt gtgttataag gaagattcag 421 agtgaattcc tggacatggt gaaacttgac acataattgt ttaccgacgc gttcaataaa 481 acgaatggtt aaaagttgtt ttttgttttt tttattttcg tataaaatgg tatttaggcg 541 ctagttacgg ggaagatcta tgggagtgat tgtgacaagg aatgaaatga atgccgacat 601 ctccttctaa tatcgttagg ttttgtgggg ttccaggcgg catgaattcc atgcgagtag 661 attctccggg ttttagagaa aagtgcaagg gtaccatatg tgcggtgtcg aacgcaacgc 721 ggagtgaact caaaaaaatt cccatgttga tgtctggcgt taagtttgca accgtgctta 781 gacttggtgt tcgcaatact gcttggtttg tgaaagttac ggtgtttctt acgggaccat 841 ttggagattc tgtgtttaca taaattttgc ttgcttctgt ccagttgaat tcgacattat 901 tccccggtgg taaaatttgt ttggggaaga agtatactac gcctataggt tgcgagtaat 961 tgatgcgacg gttcttctta aatgctttca tggtgatgta gagaggccgt gtctcatccc 1021 aaatgccggt ggttgtagag attccgagca agagtttggg tataaataaa cccgtaaagt 1081 ttgaatttga attaaagata gtgttaaaag aacaatggac aggagtaacc gtgttaggga 1141 tgatattttt agttgcgcag acagttattg aatgggtgtt gcattttaga agtgtttctt 1201 gattctgcga caatgtaatg tctgcggttt ggggggtcag tgaaatttgt atggcaagtt 1261 gttcaggata aaaattatcg tcaaggagat agtcgttttc gtagtttgcc ttcaaaatta 1321 atagatttcc gcagagtaag attctagaaa tatagacgtt tttgtgtgat ataaattcga 1381 tgttaccagt tttaaaaatt tggtcgagcg gagtgttttg gagattaacc catatctctg 1441 ccttaaatga atatcgtgtt ggctcttctg gtgtttgttc tatccatcgt atatcagcca 1501 cttgaatttt aatacgcgtg agagggccat atatgacaaa cttcgcgtcg cactgtccgt 1561 ggggtataat gtggcgatcg tgggcttcga tgcgttgcac cggtaaattt gatatattca 1621 cgtttgcgtg aggaagtgca aatatattaa ggacgatagg taatctactg agatccagat 1681 ctagatctga gatgttctgc accgcgaagg gtatgttgcc gtaatctttt ggatcgatgt 1741 aagtaaaagg cgatgatgta aaactgcttt cgtctctaca aatgcacact acggcggatg 1801 aagggggggt gatacctaat ccgcatttaa acaatctcag ttcgccgggt tttaatatgg 1861 cggtagttgt tactcttagc tgtagtacgt acgaagacca ttgtagagtg gcgggttgca 1921 tgtttgcttt tctggatgtc tgaagggaat cctgttagtg tattttggat gttaaatagt 1981 tgatgtaaac gtagagagtc atatgcgtat ttttataata gagtgttttt ccacggacgg 2041 gagagtctgc gggtttccac gcgcaggctt gtcttcgtat tctaagggat gtaatgtgag 2101 ttccggtagc aagtatgcag gaaaacaatt gcccatgaag tgtacgtcga atggtttatc 2161 ggtattctcc gtgtgtgtta aaagagattt catgtcgctg tttgagagtg aacgaaacgg 2221 ctttctaaac aacttcttcg tcacaaaaaa gacacgccct aacatgtcgt gttcggttac 2281 ggaaactgtt ctttcgcacg aaatccgcaa ttttaacggt tcttgggcaa accataaaaa 2341 tggatacagc ttgaagacat gcgtctggac agggatgaag atgcctacga tttttttgtt 2401 agtgaactcg ccgcgtagcg tgatctcttt gtttgtatta cttactaagg acatatcgtt 2461 gggaaagaaa acctctagat tcttcccgtc tgcgcagatt ttaaaatacg gcatattcat 2521 atttagcgtg acggtgctcc gatcaggggg ggaaaaggtc aagcgaagat aacattcttt 2581 cgtgattgga aaccgtcgct tgttttccgg caacactacg ttacgcaaaa agactgtgag 2641 aaaaggatcg ttaaattcta ttttgtagat agagatgccg ggttcggaaa tcatgttgac 2701 tctgcagagt gggatgatac ttttgaatag gttttcccaa tagggacatt ctctggtatc 2761 gatgctgaac acgctaaaaa ctattagcag ctttctgcca tagcggtcta atttttgaga 2821 ctgataagga ctttctgtcc agtttaggtt aaataagatc aaagacattt caacgctatc 2881 attctgaact actttaaatt gatttatcac gttggttgtc gagataggca tattggttag 2941 gccatattgt tcgtatacgg tcggatcgat gttttctttt tgacatagcg cattgatgtc 3001 gtcaatctcc agtgcatgtg acggcagata aatgggtatg gaaaataaat gaatccgtac 3061 gggaaccgtc ctagaaatag gtaaaatttt tattttgata gtcgttgttt tttcgagaaa 3121 ctgtacatcg aacagaacgt cctcagtttc cgattcagtg ccatctgtta tgaataggat 3181 tcctggtttt gtgcttgaga ttcgacattt caaaatgatt tcttggtaag aattcgaaac 3241 tatgtgattg caatcaaaaa cgagttgcaa gacatggttt agttgaggag aaaacatgct 3301 ggtacaaaaa acattttatg tttcatctcc ctttttaaat actgtgtttt tttaagggat 3361 gaggtcattt tgtatgacgg atggaggacg cgggtgtccc ggcggggtgt gtttttataa 3421 tcctgtgtat gagtgataga aaagtcatag taggctagtg tttttttaaa aagcatttaa 3481 tttttataaa tacatgtagc cattctgtta tctgcggaaa cgtcacagac aacaaaatac 3541 gttttctcgt tggtcaaaga attaatttgg tcgatcatag ttaagactga tttgactttt 3601 tttaattcat ctttaatttc cgtagcgtga agttgtccgc agcgctgtgt gtttaacgtt 3661 gttcttttag ataatagttc ttggcatttg atcaaaagca ttgaatggtc ttccagcgtt 3721 agccgatcta tgtaagttct cacgatgtct ggggccatgg ccgtgatcat ggacagcgag 3781 atgcaagctg ttttcatgga gtacattgat tgtttgtcgt tgactatgtc tggtaattta 3841 atgagtacgt ctctgtattg gatagagcat aactcatcga tgattgtttg catctcattg 3901 tattctctgt gaactgctat aagaccaatg catagcaatc tgatgttgat ctcggccgca 3961 atggctgtcg gaacgactaa aggtacagtg agctcccaat cacctagttt caatagcttt 4021 tcttccgagt gcgtcgataa aggtggaatc aatgtcaagg tgtcaccctt ttcccagggg 4081 aagggtcctg tgttctttat ggcatactga tggccggtca ccggctttct caaaaccagt 4141 tgattgcctt ccaccttttg cagaatggtt acgaccatgg tccgtaatac gtttcggacg 4201 tggacgtaat ctttgttgga ggagacgatg ggataaagac ctaaattgcc gctacctatt 4261 agatggtggt gagctgggat cggtatgacg atgttcatga gcttgcatag ggtgctgata 4321 tcggaaagtg acagtttgtg atcgaaagtg cagtagacgg tttccatttt atatggatga 4381 ttcgataatg agttggaaag gtatggtttc tcctatggcg taattacaat aatgggtttc 4441 gctgatctgc gtattgccgg ttttagaccg actctctaat agagcttggt tggatgaaca 4501 gtgaagaggc agagcgtttt gtaagaactg gcatggtctg cttacgaagc tatccgtgcc 4561 ctcagagcac gagtattgta tttcgctatc gctgtttaaa cacgagttcg atttcatgca 4621 gtattcgctt atcactttgt acatcatctt gtttgttttt aagatgtcag attcggtaaa 4681 aaattgagcg ttgggactgt atgtcttggg gttgtaacat agttgttctc tgtgtgccgt 4741 gttgtataga atatcgccta aggagcctgg tagagatgcc caagggtttg tggttgcggc 4801 gaatgtatcg ctgtctgttt gggtgtggtc gtacaatgct tttctagccg cctcttcgtt 4861 gtgcgggtcc gttcccatca tacatgattc cctgcctctt gggttgtggg gcgatttgaa 4921 aaagttaatg tttgtcgtaa ccggggtcag tataacttcg cagatagctt gttgaccatg 4981 cagtagtatg gagggtgggt ttttgttaat tccgccgaac gttatgatgt ttagtgcttc 5041 gctctcggag ggattaggtt tttctatccc gacgtgatgt cgaatccacg tatttatgtc 5101 cgcgttggta aacgcgtgta tcgggaaggc ggagaaaagg ttttgtatct tgctccccat 5161 atctgattta attcgcttaa gattggcagt ggcggtggta gagctaaaac ctaagcccat 5221 atctacaaaa cttaggtgct gggtgaagtt gtaagtggtt gcgatatctt tagcttccgc 5281 ggtgaccgtg ggatcgtcta aaattataga tgtggctgct ctggaactgt ataataggca 5341 ctcgacgtcg aaattatccg tccggactag tgtggccgca aagcccggat ggattttgtt 5401 tttgctttgg atcgctatgg caacgggaga caattttgag tgcatggcgg caagcgtcat 5461 aatgctcaac agggaattgg ggcagaaggc tgagtacacg gaaaacggtg ttcgttgcca 5521 attataaaat tctaatgcta atgggggcgg gagaggaaaa ccgccgtcgt ttctttgaca 5581 gtgaggaaat gtatttagga aaacttggat atcagcattc atggtgccgc agattcccgg 5641 gtcggagaag aatcgatgaa atgggattgg ttgatagtac cgtcttaggg tggtgatcgg 5701 tgagatcagg caaagcccgt tgtatagaat gtgttgtagt gattgaaaat gaacggagtt 5761 gccgtgtcgc tgcgcgggat ctaaggagac ttccacttcc aatattttcg tattttcatt 5821 aatgtagatt agcgatttaa acaactgttt tgcgatacag gatgtgttgg ctacggtgta 5881 gccagggccc ataccttctc ggatcagaga cattagaacg tcgctggtaa tcggattctc 5941 ctggaaataa tcatctggac tgatgaacgg ttccgtgtag aataagtcta gaactagttc 6001 ctttacgttg acgccagcgc cacaggcctt gttatttgat agtgccggga gtacgcagaa 6061 gtaaaatatc tcgctcagga tggtggtttc gttcgatggt ctgtcattgt cggtaaagac 6121 gacgcttgaa tctattagat tcattctttg cacatcggat atttcgtaat ttctaactct 6181 tacggtgttc tgtgtcagtg gtgtatcatc cgctgttatt tttgcattcg tgtcgtttct 6241 gggcatggta tggacgaacg ggcagaacag acgtccgtcg aacaacgcgt tggcgaaatt 6301 caccagaggt tcgccgcaaa gttgctcgtt gaggttggag atagagattg ttctcttcac 6361 taggcgaatt agcgacacaa gatttctgta gtgagcgaaa gctgctcccg ggatcagttc 6421 gtcgcccatg tggttagaga ttagcatgat catctcgaag ctgttgcaaa aaagaagtat 6481 atgtttcatg ttaaaccaat aagaaataca ctggctaatt acttgtttta ggatcataaa 6541 agcatgcttg tttccatgca ctaaggtctc gataacgtaa gccaattctg ggtacgagcc 6601 actcgtcaag ctttcggtga caattttgag ggtgaagtcg tacttttggc agttcgtctt 6661 tgcatgttcc agtatttgat ttgtacgggc ttcgtggaaa gagactggag ctaacggtaa 6721 aggtatgttg cctatcatta ttcttggtgt gcagagtact tctgtggctc ggtttttctg 6781 gatatacgtg agatcgaaga aggggtgtct ttcggtcggc agtgttggat tgtccggttt 6841 gtaaaaatct tcaatgttta attcgttttt taagacgttg gtgtttttgg gtacttcttg 6901 tcgactttcg tataagttgt ataaggtctg taagatcctg gctgggtttt ctcgggtaat 6961 ttttagttga catagttggg aaaagcggtg gccggtaggc aatggttcgc ttttcatgag 7021 tcgttcgacg atggtcgagt cgtggacaat gggatggcaa accgacggta atatgtcggc 7081 aaaatcaatt cgctgcacga cttggtcttt attgtggaaa aaaacgctgg tgggtaggtt 7141 gttttccatg gtgtcgttta atttcacacg tgtttccatt gtactgaaac cggtctcgct 7201 cggtatgtag atacccaaag ggaaaaagaa tgttagttgt aagctctgtt ctagcggatc 7261 gttgacgtct gtgtttttgt aaactttgtg taggtggtcg aatgcgacta atttatctcc 7321 caatttcaac gtgttcagct ttaggtcggc gtacgcgcgg cttttgtcga agatttctga 7381 tttgttgtta gtgtcttgtt gttctgtccc ggcgttcacg gtgaattgag taaaatcggc 7441 catgattgca cggtatgcaa tcgcagtcac tgcgttttct ttgcccataa taaagtgacc 7501 atatgagatt ggggcggaga cgacttgtgt ggagatgtac tgggagagta tgctggtgag 7561 tttttggata gagccgatcg gtcctaataa aacaccatct agggggacgt tttctttgga 7621 agtgtagttg ttcgtatcat ttagaatgct ttccgtgacc gattccatca tgtcgtttag 7681 aattctatag atatatgaaa tattattatt cctgttcaaa aaaaataatg acgttaacaa 7741 tctgttcttc aggctctgaa acatgttgct gcgctgtact cggctcagag cttgtttatt 7801 atgtactttg ttctcattca tggtcaggac gataaattgc gggggagatt ttctcaataa 7861 ggtttgcatg aatgcgtgaa tcaaacctcg ctcgagcgaa tcggctgaat tctttaaaga 7921 tcttaagact gtatgtaacg cattgatgtt taaaatctga tcgatgactg tgtttttaaa 7981 tgtgttttcc agatgttcca gacaggcagc gctcaaatcg aacgatatgt ttatggggtg 8041 tttttctgag tgtttggcta ccatgatggt ggtttctttt gaagcagtta cgtcgtttcc 8101 tgtagcgact ctaggtaatt gaataaagaa gagaaccttc ccgagggtca ttcgactcac 8161 atcattgaag cggattacgt tcgctgcaac ggcgatcggc gtggtgaaaa agttaatcca 8221 ttctattttg ttgcagtaga ttccgagtaa ggcttcaaaa ctgatgttgt aacggctcgg 8281 atcgtcaccg aaataaattc gcaaattgtc aaaaagttgt tcggctgtgt atgttttaat 8341 gtcattgaaa atatttagag gtgcttcgat cttaggtaaa atttcggtcg cctgccaatt 8401 ttccatgttt cggcgttatg cagcacaccg gtaattgtga aactttaata gttaattcat 8461 gttttggttc cacttgtgca cggtcgattc cagtttttat agattcgtgt gatctgaccg 8521 ctgaagtgtc tcgcgacgag gaaactcgtt tagcgcgatc catgcctgta gttctggaaa 8581 agatcgagtc aatcatagag aaaatttttc aaacgtccgg gccaaatatc gttcacgata 8641 aagacagggc taaaattgcc ttgtgtcgtc tgttgttagg accagttgcg gtgccatgct 8701 tctgtgaaga gtgggacacc aacgactatt tgtcgaaatc tggctgtaaa tgcataggtc 8761 cgatcttata tattcatacc agtcgatgtc gttgtagcga cattccggtt tttaagtttt 8821 ctattatgaa agattactat gcttcacacg tgttcagagg tttattatct ctgaaagagt 8881 ggaatacaca tctaccgaat gtattgtgta cgtgtgagtt gtcgatgagc gatagatatg 8941 tggcgacagt gtatcctaag cagaattcta tttatctaga atactatccg tattttttgt 9001 gctacctgtg tcgccatctt actgtcattg agattgagca gtgtacaaat gatttaattt 9061 cgcttcttgg ccctaaagta gctcagcgag tcataattca ttttaaactg ctttttggtt 9121 ttcgtcacaa gccgcatatt ggtactgttg attcgtggtt ctgggaaaat ttttttatgt 9181 tagaattgca taagctttgg ttaaccgtag tcaaacataa tcgggtgacg acagattttt 9241 ttaatgtagt ctacgagaaa attcaaaact ataaacaata cgcaatcaag accctgagga 9301 tgtcgtctaa ggcggttcct gcaatacaga ggttgtgttt ggcaaaattt aagcagcaat 9361 tgttgtatct aaatattaag gttacggtaa aaaaaaataa gcgagaaatg tgtttgaatg 9421 gctttgttta cggtaaaaca ttgtatgtcg ttgaatcttc tcagttaatc ttccggaatt 9481 tgcttctgtt gtattacgat tacagtttgc cggacgaatg caagacaaac gaagaaaacg 9541 ttttgacggc tcattacata cgagtaattt cgagattgtc gtttaagcgg tctcggagtg 9601 cgctcccgcc aggcgtgaga ccagatttta tctttgtggc acaacagcct aaacgtaaag 9661 agttacctaa tgttcccggt ggtatcgatt ttgctgaaat tacctcagtg aggcatggcg 9721 cggtaactct taacgcgttt aatacgaaca aagtcatgaa tttaaaagca accatttcaa 9781 aaagggctaa ctttgtatat catcgcattc ctaagacgat gacccacagt tttgtcatgt 9841 acaagcatac gtttaaagaa cctgcgttta ccgtaagcac gtttgtttca aacgatgatt 9901 tagatatgag ttcgttgaat atcaacatac gtggacctta ctgcgacttt ttatatgctt 9961 taggcgttta taagatgcat gtttctatcc gagatctatt tttaccggcg ttcgtttgca 10021 atagcaataa ttcagtggat ttacagggac tggaaaatca ggatgttgtg agaaatagaa 10081 agaaaaaggt gtattggatc actaactttc cgtgcatgat ttctaatgct aacaaagtga 10141 acgtgggatg gtttaaagca ggaacgggta ttattcctcg ggtgtctggg gaggaccttc 10201 aaaatgtttt gcttcaggaa ttaaataacg ttcgagagat tcccgggtta gtctttgata 10261 tggatttaca tcaactgctt gttttattgg aacagcgaaa tctacatcag attccgtttc 10321 tcgttaaaca gtttcttatt tttttacgtc tcggtctgtt aatgggttac gggcactctc 10381 ggcgcaacaa ggtgcatgat attatgttac atttaatttc gaatggtctg tttgatttta 10441 ataagaactc cgtagcaaat acaaaaatca aacacgggtg tgcgttggtt gggacgcggc 10501 tcgccaacaa tgttccgaaa atcattgcta ggcagaagaa aatgaagcta gatcacatgg 10561 ggcgaaatgc taattcgctc gccgtgttgc gttttatcgt taaaagtggg gaacagaaaa 10621 ataaaactgt tttcattaaa ttgttggaat atttagcgga aacctcaact gccataaata 10681 cgcggaatga agtcgccaga ttacttcaga ctctgacggc taaggtgaaa acatgaatgt 10741 actcgtggcc gacgaatggt tcgattgcgc gattaggtta gattcggaaa ccatagctgt 10801 ccatgagatt ttcaatccgg agttaagtaa actgcttaac ttgcactcga aaacagtcta 10861 catgtccgac ctatgcgctt ttatttctgg ttgtgttaat cggaatgtcg gtaaacttac 10921 catatattgg catgtgaacg gagatataat ctacgcattg acgggtattt tacattgtgt 10981 aaaaataaag atagagtgcg gggagagaat tgccgatggt cgatatagat tatacgaaat 11041 tcctaaatta tttttaatga gaggacagtc aacacccatg gaattgaagt ggaagcacgc 11101 cgtgggtatc gcgacgacga ataagccttt gctgacgcac gttttaacag atgtgttgga 11161 aacatctcct tttaccttgc cagatacgct tctgtcggtg caggagttgt ctattttcag 11221 agagagattg tcgtacattt actatgtgct ggggtcagat gttgatatcg tagcgcggac 11281 agagagagag atttttcaaa aatgtgcaga actagctcgc ctacagcaag tgttccttat 11341 tcaaggaaat attatggaaa actttgtcct cgcccaggct tgtctatttc agctgggggc 11401 tgatggtttg tgggaagaga tatctggttc tgtacgtcct aggccggaat tgatgtccag 11461 tgcgttcatt caacacagag taatgttgaa taattgttat tgtatcgctg tcatcttcaa 11521 tgccatttac aaacacaaac tttccctgcc taccgtagaa agaagccacg aaaccgttaa 11581 tcgtgtagct caggaatatt ataagtctta tgtgaatgct cctctctctg ttcttgtgtg 11641 tgcgactaag gtgcttactt tatttacaga agaatataac tttaagtcag ctctcgtatt 11701 tgtcagtcag tttttccagg tggacgtcga ggcttcgaga gcggatgtga ttcgtctgtt 11761 tttagcgtgt ctaaagggtg attaaatctc tcggaaagag gctgaactgt ttccagagca 11821 tacataaatc gccataatta tagcgataat taagtcgtcg gaacaggctt gttttttagc 11881 gctgtatgtt atgtaattgt taacggagat ctggtgaatg tttctgattt gttctagtgc 11941 gtattccacg ggatcgtagg taatttttat tgtaaacgat atcaattcct gtgacgcctt 12001 gatgtttcct gaattaaaat tcgagataaa aaactcaact gctagttttt tttctttacc 12061 gagtaggtaa aatggctgtg ctatctgatt ttggtctggg gtgtggaaaa aagtcacctg 12121 tatagattta ttagccgtga tgttttcctt tatgatacat gcaattttta cggcagaagc 12181 ttgattggaa ttcccttcta tgatgatttt tacttccgtg aagaaaggat gtagatctag 12241 gattgacaat atcatatgcg cggcacattc agctattgcc gtgtcggaac ttgtcattaa 12301 actttctaga aagtagtgct ccatgccgta gacgatatat tgatctagat aggtgcctat 12361 tgctgctatg cctgtgccag aagcacggcg gttgcctgta taggcagggt ctaggtatac 12421 gtacagatct ttacctaaaa agggaattag atttttattg atggtgctgt atcggaaaaa 12481 ctcgaattcg gtttggcctt gttccgtaat taaaacgtcg ttgatcacat tgcaagtggc 12541 tccgcccatg atttcatgga tgaaagctcc ttctaggaag aggttggccg tttttttaac 12601 ttcggcgtta atgctgatga acttgggttt gtggagtcgg tagcaagaac aggctgtggc 12661 gttaccgcgt tcgtttaaca tatgggcgtg atcttcacat acgtaagaaa ctacggagag 12721 catttcaaac ggagagttgt tcagcttcat taaaaaagat gttgaatggt ttccggaatt 12781 ggtcgaagat ataaatagga tcttggtaga tgcttggggc aggaaaccta aaatcgtgct 12841 gaacgcgtct ttctttataa agtggctctc gtcgacaata agcagattga agctctgtcc 12901 gcgtatactc tgagagggga atgaattcgg cgttaaacgg gataaaagac gattttgaga 12961 actgtgaaac gaaagacgac ctttttaaaa taattgataa aataagcaaa aattgcaatt 13021 ttatagtgga acaggtcgag tctttgcctc ggagggtgga ttcagcggcc atcctatttg 13081 ataatctcgc ggtggagata tttaacgatg taatatatcg acaaaatgga gttgccgcga 13141 aaatacgaca gggtaacggg caggatattg acacataaga ataaccagat gtgtacaacc 13201 gaatgttctc agatgtataa tttacacaat cctatcacgt ttgagttggg acttggaaac 13261 gtgtttgtct gtatgcggtg tttgacggtt caccactgtg atatgcaaac tgactgtacc 13321 attgtcaaca cgcatgaggg gtatgtctgt gcaaaaacgg gtttatttta tagcggttgg 13381 atgcctgcat atgcagactg cttcttagaa ccgatctgtg agccgaatat tgaaacggtt 13441 aatgtcgtgg tggtcttgtt atcttatgta tatagttttt tgatggaaaa caaggaacga 13501 tatgctgcca ttattgatag cattattaaa gatgggaaat ttataaaaaa cgtggaagac 13561 gctgtgtttt atacttttaa cgcggttttt actaactcaa ctttcaataa gattcctctg 13621 acgacgataa gtcgtctttt tgttcagttg attataggag gacacgctaa aggaacgatt 13681 tatgacagta atgtaattcg cgtcagtcgt cggaaacgag aagacagttt actaaaaaag 13741 atgagattgg agtatggaaa cgcacttata ctatgacacc ctgtatcaat atcaaggcgg 13801 agtgtatccg gctcatattt gcctgccgac agatgtgtgt cttccgatga gagtggattg 13861 tatcgagtct ttatattttc ggtgtgtatt ttttaagagt gggatgcatt atactgaatg 13921 gagtaaatta aagtttactg tgatttcacg tgaaataaag tttaaagatg tgttaaagga 13981 tgcggactct gacgaagttt ttaccggttt ggtggtaatg actatcccaa ttccgatagt 14041 agattttcat tttgatatcg attctgtaat tttgaaattg gtttatccgc ggttagtgca 14101 ccgggaaata gtgctgagac tctacgatct tatatgcgtc agacctccgt caaaccggcc 14161 gtcggaagca tcagctaaaa atattgctaa tgatttctat caactaacct cacgtgaaaa 14221 taaacagaca cccgatgagg aaaaacgttg tctatttttt cagcagggac ctttagagcc 14281 accctctacc gtcagaggct taaaggcgcc cggtaatgaa aagccaatac aatttcccgc 14341 ccatgctaac gaaaaaatga ccgaatcttt tttaagcgat agttggttcg gacaaaaagt 14401 cagatgcaaa aaaattttgg attttacgca aacgtatcaa gtcgtggtat gttggtacga 14461 gctttcgttt tcccgcgaga tgcagatcga gaataattta ctgtccgctt cccagctaaa 14521 gcgggttaac gctgcggatt tttgggatag aactaatcgg tatttgcgag atattggaag 14581 cagggtattg acacacatcg tgaaaacgct tcagattcat aataggcaat ttaaacagaa 14641 atttaattgc aattttccag ataatttcag ctttgatcgt ctattatcat ttatgcagct 14701 cgggaaagat ttttggattt taaacttaac tttagacagc tgcattatta aggcaattat 14761 ctgtttccta ggttttcaaa acgggggaaa atctttttta gcccaagatg aagtttgggg 14821 ggatttaata gactgttcta aaggatcggt gatctacggg gaaaagatcc aatggatttt 14881 ggactcgact aacaatttat attcgacgtg tcgggaaaaa cagaataagt cgtgggaatt 14941 atatgttgat tgctgtgctt tgtatgtatc tgaaaagtta gagttggatt ttgtgctacc 15001 cggcggattt gcaatcaccg gtaaattcgc gcttactgat ggcgatatcg actttttcaa 15061 ttggcgattt gggttatctt agaaattttc tgcagaatga atgtaactgg ttcagaattt 15121 gtaaaaaaac attctatcgc gaatatcgca gcgttgcgac atcgtctcct acattctcgt 15181 tgaataataa gcctaagaaa ttttgcatgc attgcgagat tgtaatattc aagcgaagtg 15241 aagaatttat gttcagcctt gcggtaaatg gcatacattt tgggcagttt ttaaccggaa 15301 aaatgaaatt taataagaaa gcagttccgg aagggctcta ttactatata ttggaattgg 15361 gaagcataac ccctatcgat ttgggcttta ttccgagata taattccgac tgtgttacaa 15421 acatgcgttg tgttacaccg gaggttattt atgaaaattg ctctattgtg tgtcccgaag 15481 aggcaaatcg cctcacggta aaagggtccg gggacaataa attgactccc ttaggtgggt 15541 gtggagcatg gtgtctgaaa aatggtggcg atctgtatat ctatactttt gcactcgctt 15601 acgatctttt cctaacttgt tatgacaaat ccacctttcc atctctggca aaaattattt 15661 ttgatatgat agcttgcgaa tccgaagatt gtgtcttttg taaagatcac aacaaacatg 15721 tatcgcaagc tggacagatt gtagggtgcg tctctaatca agaaacctgt ttttgctaca 15781 catcgtgtaa gaaaaaaatg gctaatatta acaatccgga gttaatctct ctgctctgtg 15841 atcaggaaat taataagata gatattatgt atcccaaaat aaaagcatcg ttatcactgg 15901 acattaattc ttacgctcat gggtacttcg gtgacgaccc ttatgcgtta aaatgtgtta 15961 attggatacc agtcaggatc agcgcagctc tgagcaggct gattgttttg tcgtgtcctg 16021 tgtgtaagcg tgtggtaatg gactaattgt gtgttttatg tattaatttt ttatttctga 16081 aaataaagtt aaattgatag tacttacgtg tgtattgtag cagctggcga aaagtgctgt 16141 gctctttata ttttgatggt cgattgtaat tacattatcc aggcatgtga ttgtcttttc 16201 tggaaacatt cggcggcatt taaactcgac ttctttcatc acaaagtgag atacgtgttt 16261 ttgatgtgcc acgtaaccga tgctgattcc ttcaatgttc ttcaataaaa aacttataat 16321 aggaactatg aaccacgttt ttccatgtct tcttgggact aggaatacgt tagttttttg 16381 tttcagcgta ttcagagtac tttcgtttac gaattcaatg tcgaacacgt gggtcagata 16441 gttgataaca cgattggcta aagctggaag tttggtgacg gcgatgaaga agattacatg 16501 tatgagaatg ttcttctgaa atggttccag ttgtattttg cgcgtgtctc caaagtcgtt 16561 gaattctcct ttgatccatt ttctgaaatc tttgataaaa ccgtctattt gcaagaacag 16621 cggttcacga tatagaatct taaaggattc aagaaattcc gtgtattgtg attcaaagga 16681 tttgtcggaa gcgggtaaaa acttcatttc ttgtagcttg tgcgaaaggc tcggtagtat 16741 agtaagaggc ttacggtttt taagatgtcg ctgtttttca caaaatgtat atagaggttt 16801 tacctgttgg ttatatgaat gggcaaagcc gagttctggc gtgagcatta taaaacgctt 16861 cttatagaag atggcactgt tggggtactt ggtagatatt gtcgagcagt ctctttcgcc 16921 tttccatatg atcgcttcat agttattttt tatgtgggtt atgtcgcagg tacgtagcat 16981 ggagcccgac cttacgttgg cggcggtcta tcaggcggcg gcgaacctca cagagcaaga 17041 taaggagatt tttgccgaag cggtaaaaac tgcgttttca gtgtgtagtt cggcagcccc 17101 gagcgctagg ttgaggatga tcgaaacgcc tacacagaat tttatgtttg tgacgagcgt 17161 tattccttcg ggtgtgacgt ctggtgaaaa aaaaacaaag ttaaatatcg atgccgctct 17221 ggataatttg gctttgtcgt ttgcgaacaa aaaatcaaag aagatggcta gaacgtattt 17281 gctgcagaac gttttgcgga ctcaagatca acaagttgcc atttcgggga agtacatttt 17341 gtatacaaaa aaacacattg aaacgtcttt gatgatcgat aagacgaagt tagttaaaaa 17401 aattctcgag tatgccgaga cccctaatct gttaggatat accgatgtgc gtgatcttga 17461 atgtttactt tggttagtgt tttgtggtcc taaaagtttt tgccagtcag acagttgttt 17521 cggatacagt aagacgggat ataatgccgc gtttccaaat ctattgcctc cgtatctgta 17581 cgaatgcggc caaaataatg gactgttttt tggcattgtg caagcttacg tgttttcttg 17641 gtactcagat tttgattttt cggcgcttga gatttcagaa cgcgctcgtc gtcgaatcag 17701 gtcactcctg tacgacttaa aacagaagtt tgcggagcaa gaagtttctg ttttatcggt 17761 agcgtcacag atgtgtatct tttgtgcatt atataaacaa aacaaactta gtctagaata 17821 cgtttctggt gacttaaaga cttctgtttt tagtccaatt ataataaagg attgtttatg 17881 cgcgcagacg acaatttcta caactcagat gctgccaggt acaaagagct cagccatatt 17941 tccggtatat gaccttcgta agctgctcgg tgcgcttgtc atttcggaag gtagtgtcaa 18001 gttcgacata taatgtcttt gaaggactat ctgagacagt ccatttctaa agatttggag 18061 gtgagacatc gagattcttt aaagattaga ttaggggaga gacatccatt gagtgtgcat 18121 cagcatatga tcgccgctag gcagatcatc aaatcggaca atgcagaaca acagcatgta 18181 atatcttctt tgagtggttt tttggataag cagaagagtt ttttaagagt gcaacaaaaa 18241 gctttaaagc agctagagaa attggacgtc gacgaaataa ttgatacggc agcggaagtg 18301 aaagcagtca gtaatgatat aaaagaaact cttataacaa gcactgaatt agaataatta 18361 tggacaacgg tgtggagaca cctcagggtc aaaaaactca gccgataaat ttaccaccag 18421 tcaggaaaaa gttaagaaaa catgagggac tcggaaaagg tgttaaacga aaactttttg 18481 ccgaagatag ctctccctta aagaaacaga tttccgcctg cagtgatatg gaaacacttt 18541 cttcgcctgt aaagtctgaa tgcgagtcgc gaagtgcttc tctcgatgaa agtttcggaa 18601 aatgtaaaca cgaaattgct tgcgattgtt ctgcgataga ggaattgctt tgtcacgagt 18661 cgcttctaga ctcgccgatg aaactgtcga atgcccacac catcttcagc tcaaacaaat 18721 ggaaactgga gctagagaaa attatagctt caaagcagat ttttctagac atgagtgaga 18781 atgctgaact tgcggcctac ggcgaaactt tgtgtaacct gagaattttc gaaaagatca 18841 gctcgccgtt tttgtttgat gtgcaaagcg aagagcgttc gtattcagtg gtctacgtcc 18901 ctcacaacaa agaactctgt ggacagtttt gtcaacctga gaaaactatg gctcgagttc 18961 tcggagtggg tgcttacggg aaggtgtttg atctagataa agtggccata aagacggcca 19021 atgaagatga gagtgtcatt tcggctttca tagctggtgt catccgtgca aaatcaggag 19081 ccgacttatt atctcacgag tgtgttatta ataacctatt gatttcaaat tccgtttgta 19141 tgagtcataa agtgtctttg tcacgtactt atgatattga tctccataag ttcgaagatt 19201 gggatgtcag gaatgtaatg aattactaca gtgtgttttg taagttagct gatgctgtaa 19261 ggtttctaaa tctgaaatgt agaattaatc atttcgatat ctcacctatg aatatatttt 19321 taaatcataa aaaagagatc atctttgatg ccgtgttggc ggattacagc ttgtccgaga 19381 tgcatcccaa ttataacggc acgtgtgcta ttgctaaaga gtatgacaaa aatcttcaac 19441 ttgtgccaat tagtcgtaac aaattctgtg acatgtttaa tcctggattt cgaccacttg 19501 tcgccaatgc aatgatattg gtcaatgtgt gcggggcttt tgatggtgaa aataatcctc 19561 ttagacactg taacttggat ctgtgtgctt ttgcccaggt tgtattatcg tgtgtgctaa 19621 gaatgacgga taaacgtgga tgccgcgaag ctcagttata ctacgagaaa aggttgtttg 19681 ccttggctaa cgaggcctgt cgattgaatc ctctcaaata tccatttgct tacagggatg 19741 cttgctgtaa agtattggct gagcatgtag tattactagg gttattgttt taccgagacg 19801 tggttgagat atatgaaaaa ctatacgatt ttctagatga gagaggggaa tttgggtcac 19861 gagacctttt tgaggcaact tttttaaata atagtaaact taccagacgt cagccaatca 19921 gagagggtct cgcgtctcta cagtcgtccg agtatggaga aaaactttta catgacctta 19981 gagagttgtt cttgatcaat tctactgcgg atctggataa agatacatca tctctctttc 20041 atatgtgata tagtaatgga tcttgatcaa atatctgaaa cactgagttc tgtggccgaa 20101 gaagagcctt taaccatgtt tttacttgat aaactgtatg caatacggga aaagatcaag 20161 caagttccat tttcaattgt tcgcttgtgt catgtttact gcatgctaat aaaatataac 20221 gcttctaaca ataattgcat tctgggccgt aaacttattg aggaaatgca gcagtttttg 20281 tgcggcacaa gagtggatgg atcggaagac atttctatgg atctgagtga attgtgcaag 20341 ctgtatgatt actgtccatt attgtgttct gctctgtgtc gtgcgccttg tgtatctgtg 20401 aacaagttat ttaaaatcgt agagcgtgaa actcgggggc agtcggaaaa tcccctctgg 20461 cacgcgttac ggaaatatac cgtgacggcg actaagttgt atgacatcta tacgacaaga 20521 tgttttttag agtataaagg acagcagttt tttggggaag cggtgattta tggcgcgaaa 20581 catgagcgtg ttattagaca cctcgtagcg accttttacg ttaaaaggga agttaaggaa 20641 acgttgggat tgctgcttga tccttcttct ggagtttttg gcgcgtctct agacgcgtgt 20701 tttggaattt cattcaatga ggatggattc ctgatggtta aggaaaaagc gctgattttt 20761 gagattaaat tcaaatataa atatttacgg gataaagaag atcactttgt ttctgaacta 20821 ttaaaaaacc ccacggagaa atccttttcg gattttattt tatctcatcc ggtgcctgtc 20881 atagagtttc gagaaagagg gaagattccg tcatctagag aatatttaat gacgtatgat 20941 tttcaatatc gtcctcagag aaagttgcgt acttgcccca ctccagctat tttggcacct 21001 catatcaaac aactgctgtg tttgaacgaa acacagaaat ctacggtaat cgtttttgat 21061 tgtaagagcg acttgtgtga gcagaagctg tctgtgtttc agaaggctgt gtttactgtg 21121 aatgtattcg taaatccgaa acacaggtat ttttttcaga gtctgttaca acaatatgta 21181 atgactcagt tttatattaa tgatcataat aatccagaat atatcgaaag tacggaagtg 21241 ccttctgttc acattgtgac ggctttcttc aggagaagaa cagaggaaga aaggagtttg 21301 catttggtga ttgatgagac agaatatata gaagaagaaa tacctttggc cttgattgtg 21361 actccggtag caccgaatcc ggaatttact tgttgtgtta taacagacat atgcaatctg 21421 tgggaaaata atatttgcaa gcagaccagt ttacaggtat gggcgcaaag tgctgtaaac 21481 cagtatcttg cggcatgtgt aagaaaaccg aaaacacctt gattgattac aagggaaatc 21541 ctatattact agcgaatgaa tttactgttt taaccgatac cgaatcggaa gaggaaggga 21601 tggcagatct tgaaaagccc ttacttgaaa aagtagttgc taagtgtgat acggaagctg 21661 aaaaaaaatt gccttgtaaa tcaaaaaaat gatagacgac gcagatttac ggcacgctcg 21721 ttttttttta ttttttggct atttgacaat aaacatgatt gtaataaagt gtcactcgtt 21781 ttcatccatt aggctcgagc tttcagtatt aactagttgc ttgtaccgac gcttcttttt 21841 aactaggtag cgtacaag //