GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS HUMCFDELTA 58 bp ds-DNA PRI 23-MAY-1991
DEFINITION Human cystic fibrosis (CFTR) gene, exon 19.
ACCESSION M65198
KEYWORDS cystic fibrosis; mutation.
SOURCE Human (Soviet patient CF382delT) DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 58)
AUTHORS White,M.B., Krueger,L.J., Holsclaw,D.S.Jr.., Gerrard,B.C.,
Stewart,C., Quittell,L., Dolganov,G., Baranov,V., Ivaschenko,T.,
Kapronov,N.I., Sebastio,G., Castiglione,O. and Dean,M.
TITLE Detection of three rare frameshift mutations in the cystic fibrosis
gene in an african-american (CF444delA), an italian (CF2522insC),
and a soviet (CF3821delT)
JOURNAL Genomics 10, 266-269 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 1..58
/number=19
/note="This sequence consists of a new frameshift mutation
in which a thymine is deleted in exon 19. Between the
thymine at 42 and the cytosine at 43, a thymine has been
deleted in the mutant sequence."
/gene="CFTR gene"
BASE COUNT 24 a 11 c 10 g 13 t
ORIGIN
1 agcaaaatac acagaaggtg gaaatgccat attagagaac attccttctc aataagtc
//