GenBank-Updates@genbank.bio.net (05/25/91)
LOCUS HUMPCI5 1213 bp ds-DNA PRI 25-MAY-1991
DEFINITION Human protein C inhibitor gene, exon 5.
ACCESSION M64884
KEYWORDS plasminogen activator inhibitor 3; protein C inhibitor.
SEGMENT 5 of 5
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS Suzuki,K., Deyashiki,Y., Nishioka,J., Kurachi,K., Akira,M.,
Yamamoto,S. and Hashimoto,S.
TITLE Characterization of a cDNA for human protein C inhibitor. A new
member of the plasma serine protease inhibitor superfamily
JOURNAL J. Biol. Chem. 262, 611-616 (1987)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1213)
AUTHORS Meijers,J.C. and Chung,D.W.
TITLE Organization of the gene coding for human protein C inhibitor
(plasminogen activator inhibtor-3). Assignment of the gene to
chromosome 14
JOURNAL J. Biol. Chem. (1991) In press
STANDARD full automatic
FEATURES Location/Qualifiers
intron <1..72
/number=4
/gene="PCI"
CDS join(M64881:167..785,M64882:144..414,M64883:99..246,
73..255)
/product="plasminogen activator inhibitor 3"
/gene="PCI"
/codon_start=167
mat_peptide join(M64881:224..785,M64882:144..414,M64883:99..246,
73..252)
/product="plasminogen activator inhibitor 3"
/gene="PCI"
/codon_start=224
exon 73..1124
/number=5
/gene="PCI"
3'UTR 266..1124
conflict 349..349
/note="replace (349,'ga')"
/citation=[1]
conflict 366..366
/note="replace (366,'ga')"
/citation=[1]
conflict 395..395
/note="replace (395,'gg')"
/citation=[1]
conflict 464..464
/note="replace (464,'')"
/citation=[1]
conflict 518..518
/note="replace(518,'ga')"
/citation=[1]
conflict 582..582
/note="replace (582,'g')"
/citation=[1]
conflict 589..589
/note="replace (589,'')"
/citation=[1]
conflict 635..635
/note="replace (635,'gc')"
/citation=[1]
polyA_site 1124..1124
BASE COUNT 305 a 269 c 318 g 321 t
ORIGIN
1 aagctttgcc atttgctatg atgacttcac ctgcccctgg tggcctggtg atgcctggtg
61 tctcccctgc agatggtgca caaagctgtg gtggaggtgg acgagtcggg aaccagagca
121 gcggcagcca cggggacaat cttcactttc aggtcggccc gcctgaactc tcagaggcta
181 gtgttcaaca ggccctttct gatgttcatt gtggataaca acatcctctt ccttggcaaa
241 gtgaaccgcc cctgaggtgg ggcttctcct gaaatctaca ggcctcaggg tgggagatga
301 agggggctat gctatggccc atctgtatgc tggtagctag tgatttacac aggtttagtt
361 gactaatgag gcattacaaa taatattact ctatgatgat tgcttccacc cacacgactg
421 caacatacag gtgccttggg gaaatgtgga gaacattcaa tcttgccgtc actattcatc
481 aatgaagatt agcactgaga tccagagagg ctggatgact tgctcaagtt caccagcatg
541 gtagtggcaa agagaggtcc agagtcctgg cccttgatgc ccagctcagt gccacaaagc
601 tcagtaggag ggatgttcca gtggatgagg gccaccagga agcacaggtc caaggctggt
661 cccacactta tcagcagcaa caactgtcag ttcatcctgc atgggaaaaa tgttggaatg
721 ggagtctgaa atggggctac tgtttcagtc ctaacgtgct gtgtgacatt gggacaacac
781 tttccctctc tggacctcag tttccctctg tatacaagga tcagattctt gctgtgaccc
841 aagaactcct gaaatcatat agaaaggctg gggtgggccc tgtcattcgt ggttgatttc
901 aatacactca agtgccattc atcctttaag aaaaacatct ggatatcaag gtggaaatgg
961 cccatttaat gattgattat atcattttgt ggatatagtt ataatctgat gggcctggct
1021 gggagtggaa gaagggaagc cttttgcaaa tagtagagtg tcagttgcag gtgccaatga
1081 ctaacttttt gaattctatg ttggcattaa caataaagca ttttgcaaac actggttata
1141 actgtcttta tggaggcagc tctgggaatg gtgacattga tagcttacca tgctccaggc
1201 cgggtgcctg gcc
//