GenBank-Updates@genbank.bio.net (05/23/91)
LOCUS MUSCATHB9 3951 bp ds-DNA ROD 23-MAY-1991
DEFINITION Mouse cathepsin B gene, exon 10.
ACCESSION M65270
KEYWORDS cathepsin B; lysosomal thiol proteinase.
SOURCE Mouse embryo DNA, clones lambda-mEGB2, lambda-mGB8, pmBG550 and
pmGB700.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 3951)
AUTHORS Qian,F., Frankfater,A., Chan,S.J. and Steiner,D.F.
TITLE The structure of the mouse cathepsin B gene and its putative
promoter
JOURNAL DNA Cell Biol. 10, 159-168 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M65269:298..429,1..135)
/number=9
/note="500 bp gap"
/gene="cathepsin B"
CDS join(M65263:251..376,M65264:154..239,M65265:80..194,
M65266:195..313,M65267:66..151,M65267:386..529,
M65268:186..302,M65269:169..297,136..233)
/product="cathepsin B"
/gene="cathepsin B"
/codon_start=251
mRNA join(M65262:830..929,M65263:226..376,M65264:154..239,
M65265:80..194,M65266:195..313,M65267:66..151,
M65267:386..529,M65268:186..302,M65269:169..297,136..1036)
/product="cathepsin B"
/gene="cathepsin B"
mRNA join(M65262:830..929,M65263:226..376,M65264:154..239,
M65265:80..194,M65266:195..313,M65267:66..151,
M65267:386..529,M65268:186..302,M65269:169..297,136..2657)
/product="cathepsin B"
/gene="cathepsin B"
mRNA join(M65262:830..929,M65263:226..376,M65264:154..239,
M65265:80..194,M65266:195..313,M65267:66..151,
M65267:386..529,M65268:186..302,M65269:169..297,136..3836)
/product="cathepsin B"
/gene="cathepsin B"
exon 136..1036
/number=10
/gene="cathepsin B"
exon 136..2657
/number=10
/gene="cathepsin B"
exon 136..3836
/number=10
/gene="cathepsin B"
polyA_signal 1012..1017
/gene="bPL"
polyA_signal 2638..2645
/gene="bPL"
polyA_signal 3815..3821
/gene="bPL"
BASE COUNT 1004 a 977 c 920 g 1050 t
ORIGIN
1 caggtagctc acctggctcc tgtgggtgga tgtgtgtggc caacctgtta cagagtgggg
61 catcctatga acatagtaag ggttaggcca agctcagagc atactttgaa agcatctact
121 ttttctccat cccaggcttc tttaaaatcc tcagaggaga aaaccactgt ggcattgaat
181 cagaaattgt ggctggaatc ccacgcactg accagtactg gggaagattc taatctgctt
241 tgacttcatt gtccagtcct tagggccttt ttccaaaatt tagcggccct ggcagggaat
301 gaggtagaca ggggagtctt tgattctttg agttcatcta acatgcatga agcttttggc
361 aagatttgga cgactggacc agagctgcct gccatcagag ctaccctcca aacactgtcc
421 ttacctggcc tcctcctagc ccatcccacg acagtgatca cagtctgcat cctagcctct
481 ccctagacta gtgcggtttg aagtgcctgc tgttgtggct ctgctgccat acctcccacc
541 cccatcccca tcccagcatc cgaggaccca agggctttga ctgcaggact tccaaaagaa
601 cgaacattca cgagaggaca aatgccacct ctcagctgca tcttgaagct ggtacttctg
661 ggcttgtggc aggcattcgt caatggccca gtgcagttct ctggagaaag ctaccttttc
721 ccaaggcatc tgcatccatc gacattggta atgtggccag ctctccttgg tcctgtcctc
781 agccgatgct ttttcaatag gatttttatg ctttgtgtac ctcaaccaag tatgaagagc
841 tgtactggtt ttatagactc acccccaatt gtatggctta aaacaagcta catggtcatg
901 gtttgctgtg tgaccgacag ataaccacaa tgaaactagt ctggaaaaaa aaacttgctt
961 tttgttgtag ttaccactta accctgtagt ttaacaagga atgtctgtgc caataaacca
1021 attctccctc tgcttgacat tggcagggcg gcaacggttc tgtgctgcag tttcaaggct
1081 tttgtctctg gccctggttt cctgtcaccc tcagaaatgg ttctcaaacc gtacctgtaa
1141 ctgctcacac ctcggagcac ttcctcctgc ttagagataa gggagctaca cttgtttaat
1201 taaccaaggc gggcactcac atacatatga cccggactgc catcttctta gaggtcattt
1261 cctggagtgg gggccaaagc ttgcgcacca tgtttaagtt ttctgggtta ctggatttca
1321 tggattttca tggattttac caaaaatcat agtgaagtac agttcaaagg gaacagggag
1381 cctcactcat cagcgttgtc ctatggatct gttacttcct gctaagtgag agggaggggc
1441 tggtttctct ggaagcccgc cttcccatgt cggcaatcag aactatatca aagaagctct
1501 ggatgcctgg cgagtgctag aagtgtaact cggtttgagg caacctggct tgggtactgg
1561 ggctttagta ctgcaagaca gttccaccgg tctcaactac gcccaatagt tccctcctac
1621 gcttcctttc ttgcctcacc acatgcccac ctgcaactcc ctccctacct cgcatagcca
1681 gtgaagatga gctaaattaa gagaagagga ccctgaacat cctctgatgg agcccaggaa
1741 acccgttttg ttatcgtatg cttgggggta ctctagatgt cttccataac cagattctcc
1801 tgttggtggg tttcctgtgc tcaagtcaag agctgtcttc cttggtacat gaaatggata
1861 ctcaggagac agaggcaagc cagtctctgg gagtttgagg ccagactggt ctacaataga
1921 ccttgaagct aggagcattt ccttttcagc ctgccacagg gccttttgat gattctgtgt
1981 ttacacatcc ctacctttct acacattaga ctagaacacg ccgttgtgtg ttctttgtgt
2041 ggtcctcaaa cctgagccag tatgagtgcc aggcctttga atagtcgttt gtagcccgac
2101 taggtcattt cagatagatt tgggcgatgg ccttcaaaca gggcctatga cagacagcat
2161 tcatgctgcc caggaactca ttaggtaaca tgccagatca acttggtcag aagtcttgtt
2221 ccagatccat tagaatacag aactagcctt agcgctctca cttccactac cacagagcct
2281 gggaaactca acagcagggg gaacgccttc aaagggctgt cccagacagg atttgcaaat
2341 aaccagagga aggtagcaag cacatctttc taataattat gtctgatatg ggtgggcctc
2401 tgagaagcac acagatggtg taaattatat tgagagtcaa aagcaggcct agggatgtct
2461 ccatggtaga gtgtttgtcc agcatattgt ccaagccaag acccttggtt ccagtgccca
2521 gccaaccacc aataaccagg agaaagaggt gtgtcatatg tagacagtat gtataatgtc
2581 cgactaaatg tatttctaga taatggcttt atagaaatgc accatgctaa atatctgaat
2641 ataaagaaaa ctatctgaaa ttcaagtgga acttggggtc ttatttgcta agggaaataa
2701 gtttcagggg gttagagtct gtccccccta cccctttata tttattcatg cagtttatga
2761 gtactctgtc ttcatgcaca tcagaaggaa tcggatctct attatagatg gtagtgagcc
2821 actatggggt tgctgggaat tgaacttagg acctctggaa gaacactcag gtgctgagcc
2881 atctctccag cctccaggtt ttgatgttag agacagtgtc ttatgtagtc caggcccacc
2941 tccacaactg aggaggatct taaaatccaa ctcctccctt cctccatggc ctccctccac
3001 ctcccacatg ctgggattac tggtaagagt tgtagcttcc agaaaggatg aacattaaac
3061 ttcggtttca gcggggtcgg tatttgttca aggcttagag caagtgacca atgaagtctc
3121 catgccccag taatccagca aggaatctgt gcttacaaag ttgaatggac cactgaactg
3181 gccgaggcac ctcagtgatg aagtcaacat acgcagcagg cttaagaggg gagcagacta
3241 tgctctacat gtctctgtgg tctgagcgta cccaaagggt catatacagg ttcacaaaat
3301 gacaggtagc tgaggcactg ttctcaaaag gctcaatgct agtcttccag agttagggct
3361 ccagagacca agctctgtgg acaacagtgg ggtggctcgt gcctataact cgtacattca
3421 gaaggctgag gcagtgggat caccattaaa ttcaaggcta catagacttg caggccaacc
3481 tgagctacag ttacagtgta caagtgtcag catgccaggg cgtcgactcc tgcttcctgt
3541 cacgtgctct ctcctgcatg tcctctctct actgtagtgt catttctcac aaggccgtcc
3601 aagggctaaa gatggggccc ccctcatctt gtactttcat cctcctaagc tgttacataa
3661 acaatcctct ttccttggta aagcagttgg cctcaggtat cttgtcctac caggtcaaga
3721 gtggttgcct agagcctctc caccgctcaa catggtttca gatacacagg gtgtcagagg
3781 ccaccatgac aatgtagcca actaaccacg ctgcaattaa aaacctacca atatagaact
3841 ggttttcctg tcatcatttg tcttttgaga cttcaagaaa aaccaaagca aatgactgtg
3901 aggagactgg agggaggggc aaacagcggt ggctaaagca gagggttggc c
//GenBank-Updates@genbank.bio.net (05/25/91)
LOCUS MUSCATHB9 3951 bp ds-DNA ROD 25-MAY-1991
DEFINITION Mouse cathepsin B gene, exon 10.
ACCESSION M65270
KEYWORDS cathepsin B; lysosomal thiol proteinase.
SEGMENT 9 of 9
SOURCE Mouse embryo DNA, clones lambda-mEGB2, lambda-mGB8, pmBG550 and
pmGB700.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 3951)
AUTHORS Qian,F., Frankfater,A., Chan,S.J. and Steiner,D.F.
TITLE The structure of the mouse cathepsin B gene and its putative
promoter
JOURNAL DNA Cell Biol. 10, 159-168 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M65269:298..429,1..135)
/number=9
/note="500 bp gap"
/gene="cathepsin B"
CDS join(M65263:251..376,M65264:154..239,M65265:80..194,
M65266:195..313,M65267:66..151,M65267:386..529,
M65268:186..302,M65269:169..297,136..233)
/product="cathepsin B"
/gene="cathepsin B"
/codon_start=251
mRNA join(M65262:830..929,M65263:226..376,M65264:154..239,
M65265:80..194,M65266:195..313,M65267:66..151,
M65267:386..529,M65268:186..302,M65269:169..297,136..1036)
/product="cathepsin B"
/gene="cathepsin B"
mRNA join(M65262:830..929,M65263:226..376,M65264:154..239,
M65265:80..194,M65266:195..313,M65267:66..151,
M65267:386..529,M65268:186..302,M65269:169..297,136..2657)
/product="cathepsin B"
/gene="cathepsin B"
mRNA join(M65262:830..929,M65263:226..376,M65264:154..239,
M65265:80..194,M65266:195..313,M65267:66..151,
M65267:386..529,M65268:186..302,M65269:169..297,136..3836)
/product="cathepsin B"
/gene="cathepsin B"
exon 136..1036
/number=10
/gene="cathepsin B"
exon 136..2657
/number=10
/gene="cathepsin B"
exon 136..3836
/number=10
/gene="cathepsin B"
polyA_signal 1012..1017
/gene="bPL"
polyA_signal 2638..2645
/gene="bPL"
polyA_signal 3815..3821
/gene="bPL"
BASE COUNT 1004 a 977 c 920 g 1050 t
ORIGIN
1 caggtagctc acctggctcc tgtgggtgga tgtgtgtggc caacctgtta cagagtgggg
61 catcctatga acatagtaag ggttaggcca agctcagagc atactttgaa agcatctact
121 ttttctccat cccaggcttc tttaaaatcc tcagaggaga aaaccactgt ggcattgaat
181 cagaaattgt ggctggaatc ccacgcactg accagtactg gggaagattc taatctgctt
241 tgacttcatt gtccagtcct tagggccttt ttccaaaatt tagcggccct ggcagggaat
301 gaggtagaca ggggagtctt tgattctttg agttcatcta acatgcatga agcttttggc
361 aagatttgga cgactggacc agagctgcct gccatcagag ctaccctcca aacactgtcc
421 ttacctggcc tcctcctagc ccatcccacg acagtgatca cagtctgcat cctagcctct
481 ccctagacta gtgcggtttg aagtgcctgc tgttgtggct ctgctgccat acctcccacc
541 cccatcccca tcccagcatc cgaggaccca agggctttga ctgcaggact tccaaaagaa
601 cgaacattca cgagaggaca aatgccacct ctcagctgca tcttgaagct ggtacttctg
661 ggcttgtggc aggcattcgt caatggccca gtgcagttct ctggagaaag ctaccttttc
721 ccaaggcatc tgcatccatc gacattggta atgtggccag ctctccttgg tcctgtcctc
781 agccgatgct ttttcaatag gatttttatg ctttgtgtac ctcaaccaag tatgaagagc
841 tgtactggtt ttatagactc acccccaatt gtatggctta aaacaagcta catggtcatg
901 gtttgctgtg tgaccgacag ataaccacaa tgaaactagt ctggaaaaaa aaacttgctt
961 tttgttgtag ttaccactta accctgtagt ttaacaagga atgtctgtgc caataaacca
1021 attctccctc tgcttgacat tggcagggcg gcaacggttc tgtgctgcag tttcaaggct
1081 tttgtctctg gccctggttt cctgtcaccc tcagaaatgg ttctcaaacc gtacctgtaa
1141 ctgctcacac ctcggagcac ttcctcctgc ttagagataa gggagctaca cttgtttaat
1201 taaccaaggc gggcactcac atacatatga cccggactgc catcttctta gaggtcattt
1261 cctggagtgg gggccaaagc ttgcgcacca tgtttaagtt ttctgggtta ctggatttca
1321 tggattttca tggattttac caaaaatcat agtgaagtac agttcaaagg gaacagggag
1381 cctcactcat cagcgttgtc ctatggatct gttacttcct gctaagtgag agggaggggc
1441 tggtttctct ggaagcccgc cttcccatgt cggcaatcag aactatatca aagaagctct
1501 ggatgcctgg cgagtgctag aagtgtaact cggtttgagg caacctggct tgggtactgg
1561 ggctttagta ctgcaagaca gttccaccgg tctcaactac gcccaatagt tccctcctac
1621 gcttcctttc ttgcctcacc acatgcccac ctgcaactcc ctccctacct cgcatagcca
1681 gtgaagatga gctaaattaa gagaagagga ccctgaacat cctctgatgg agcccaggaa
1741 acccgttttg ttatcgtatg cttgggggta ctctagatgt cttccataac cagattctcc
1801 tgttggtggg tttcctgtgc tcaagtcaag agctgtcttc cttggtacat gaaatggata
1861 ctcaggagac agaggcaagc cagtctctgg gagtttgagg ccagactggt ctacaataga
1921 ccttgaagct aggagcattt ccttttcagc ctgccacagg gccttttgat gattctgtgt
1981 ttacacatcc ctacctttct acacattaga ctagaacacg ccgttgtgtg ttctttgtgt
2041 ggtcctcaaa cctgagccag tatgagtgcc aggcctttga atagtcgttt gtagcccgac
2101 taggtcattt cagatagatt tgggcgatgg ccttcaaaca gggcctatga cagacagcat
2161 tcatgctgcc caggaactca ttaggtaaca tgccagatca acttggtcag aagtcttgtt
2221 ccagatccat tagaatacag aactagcctt agcgctctca cttccactac cacagagcct
2281 gggaaactca acagcagggg gaacgccttc aaagggctgt cccagacagg atttgcaaat
2341 aaccagagga aggtagcaag cacatctttc taataattat gtctgatatg ggtgggcctc
2401 tgagaagcac acagatggtg taaattatat tgagagtcaa aagcaggcct agggatgtct
2461 ccatggtaga gtgtttgtcc agcatattgt ccaagccaag acccttggtt ccagtgccca
2521 gccaaccacc aataaccagg agaaagaggt gtgtcatatg tagacagtat gtataatgtc
2581 cgactaaatg tatttctaga taatggcttt atagaaatgc accatgctaa atatctgaat
2641 ataaagaaaa ctatctgaaa ttcaagtgga acttggggtc ttatttgcta agggaaataa
2701 gtttcagggg gttagagtct gtccccccta cccctttata tttattcatg cagtttatga
2761 gtactctgtc ttcatgcaca tcagaaggaa tcggatctct attatagatg gtagtgagcc
2821 actatggggt tgctgggaat tgaacttagg acctctggaa gaacactcag gtgctgagcc
2881 atctctccag cctccaggtt ttgatgttag agacagtgtc ttatgtagtc caggcccacc
2941 tccacaactg aggaggatct taaaatccaa ctcctccctt cctccatggc ctccctccac
3001 ctcccacatg ctgggattac tggtaagagt tgtagcttcc agaaaggatg aacattaaac
3061 ttcggtttca gcggggtcgg tatttgttca aggcttagag caagtgacca atgaagtctc
3121 catgccccag taatccagca aggaatctgt gcttacaaag ttgaatggac cactgaactg
3181 gccgaggcac ctcagtgatg aagtcaacat acgcagcagg cttaagaggg gagcagacta
3241 tgctctacat gtctctgtgg tctgagcgta cccaaagggt catatacagg ttcacaaaat
3301 gacaggtagc tgaggcactg ttctcaaaag gctcaatgct agtcttccag agttagggct
3361 ccagagacca agctctgtgg acaacagtgg ggtggctcgt gcctataact cgtacattca
3421 gaaggctgag gcagtgggat caccattaaa ttcaaggcta catagacttg caggccaacc
3481 tgagctacag ttacagtgta caagtgtcag catgccaggg cgtcgactcc tgcttcctgt
3541 cacgtgctct ctcctgcatg tcctctctct actgtagtgt catttctcac aaggccgtcc
3601 aagggctaaa gatggggccc ccctcatctt gtactttcat cctcctaagc tgttacataa
3661 acaatcctct ttccttggta aagcagttgg cctcaggtat cttgtcctac caggtcaaga
3721 gtggttgcct agagcctctc caccgctcaa catggtttca gatacacagg gtgtcagagg
3781 ccaccatgac aatgtagcca actaaccacg ctgcaattaa aaacctacca atatagaact
3841 ggttttcctg tcatcatttg tcttttgaga cttcaagaaa aaccaaagca aatgactgtg
3901 aggagactgg agggaggggc aaacagcggt ggctaaagca gagggttggc c
//