GenBank-Updates@genbank.bio.net (05/25/91)
LOCUS RATHGFR 2431 bp ss-mRNA ROD 25-MAY-1991
DEFINITION Rat mRNA for hepatocyte growth factor
ACCESSION X54400
KEYWORDS hepatocyte growth factor.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2431)
AUTHORS Kitamura,N.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Okajima,A., Miyazawa,K. and Kitamura,N.
TITLE Primary structure of rat hepatocyte growth factor and induction of
its mRNA during liver regeneration following hepatic injury
JOURNAL Eur. J. Biochem. 193, 375-381 (1990)
STANDARD full staff_review
COMMENT *source: strain=wistar; developmental stage=adult; *source: tissue
type=liver;
Data kindly reviewed (15-MAR-1991) by Kitamura N.
From EMBL 26 entry RNHGFR; dated 16-APR-1991.
FEATURES Location/Qualifiers
sig_peptide 42..>42
/note="signal peptide cleavage site not determined"
mat_peptide ..2225
/note="signal peptide cleavage site not determined"
/product="hepatocyte growth factor"
CDS 42..2228
/product="hepatocyte growth factor precursor"
/codon_start=42
BASE COUNT 728 a 507 c 575 g 621 t
ORIGIN
1 ggcatctcct gcagagggat cagcctgctc gaactgcaag catgatgtgg gggaccaaac
61 ttctgccggt cctgttgctg cagcatgtcc tgctgcacct cctcctgctt cctgtcacca
121 tcccctatgc agaaggacag aagaagagaa gaaatactct tcatgaattc aaaaagtcag
181 caaaaactac tcttaccaag gaagacccat tagtgaagat taaaaccaaa aaagtgaact
241 ctgcagatga gtgtgccaac aggtgcatca gaaacaaggg ctttccattc acttgcaagg
301 cctttgtttt tgataagtcg agaaaacgat gctactggta tcctttcaat agtatgtcaa
361 gtggagtgaa aaaagggttt ggccatgaat ttgacctcta tgaaaacaaa gactatatta
421 gaaattgcat cattggtaaa ggaggcagct ataaggggac agtatccatc actaagagtg
481 gcatcaagtg ccagccttgg aattccatga tcccccatga acacagcttt ttgccttcga
541 gctatcgcgg taaagaccta caggaaaact actgtcgaaa tcctcgaggg gaagaagggg
601 gaccctggtg tttcacaagc aatccagagg tacgctacga agtctgtgac attcctcagt
661 gttcagaagt tgaatgcatg acctgcaacg gtgaaagcta cagaggtccc atggatcaca
721 cagaatcagg caagacatgt cagcgctggg atcagcagac accacaccgg cacaaattct
781 tgccggaaag atatcccgac aagggctttg atgataatta ttgccgcaat cccgatggca
841 agccgaggcc atggtgctac actcttgacc ctgacacccc ttgggagtat tgtgcaatta
901 aaatgtgcgc tcacagtgct gtgaatgaga ctgatgttcc catggaaaca actgaatgta
961 taaaaggcca aggagaaggt tacaggggaa ccaccaatac catttggaat ggaattccgt
1021 gtcagcgttg ggattcgcag tacccccaca agcatgacat cactcccgag aacttcaaat
1081 gcaaggacct tagagaaaat tattgccgca atccggatgg ggctgaatca ccatggtgtt
1141 ttaccactga tccaaacatc cgagttggtt actgctctca aattcccaaa tgtgacgtgt
1201 caagtggaca agattgttat cgtggcaatg ggaaaaacta catgggcaac ttatccaaaa
1261 caaggtctgg actcacatgt tccatgtggg acaagaatat ggaggattta caccgtcata
1321 tcttctggga gccagacgct agcaagttga ctaagaatta ctgccggaac cccgatgacg
1381 acgcccatgg accttggtgc tacacaggga atcctctcgt tccttgggat tattgcccta
1441 tttcccgttg tgaaggagat actacaccta caattgtcaa tttggaccat cctgtaatat
1501 cctgtgccaa aacaaaacaa ctgcgagttg taaatggcat tccaacacaa acaacagtag
1561 ggtggatggt tagtttgaaa tacaggaata aacacatctg tgggggatca ttgataaagg
1621 aaagttgggt tcttactgca aggcaatgtt ttccagctag aaacaaagac ttgaaagact
1681 atgaagcttg gcttggaatc catgatgtcc atgagagagg cgaggagaaa cgcaaacaga
1741 tcttaaacat ttcccagcta gtctatggac ctgaaggctc agatttggtt ttactgaagc
1801 ttgctcgccc tgcaatcctg gataactttg tcagtacaat tgatttacct agttatggct
1861 gtacaatccc tgaaaagact acttgcagta tttacggctg gggctacact ggattgatca
1921 acgcagatgg tttattacga gtagctcatc tgtatattat ggggaatgag aaatgcagtc
1981 agcaccatca aggcaaggtg actttgaatg agtctgaatt atgtgctggg gctgaaaaga
2041 ttggatcagg accttgtgag ggagattatg gtggcccact catttgtgaa caacacaaaa
2101 tgagaatggt tcttggtgtc attgttcctg gtcgtggatg tgccatccca aatcgtcctg
2161 gtatttttgt tcgagtagca tattatgcaa aatggataca caaagtaatt ttgacataca
2221 agttgtaata gccatagaag aggccagtgt atttgaagca tccatggata caggaagatt
2281 tccaagactt caggattaaa atgtcaccta aaacaatcct aaaacaacta cttgagtgtt
2341 gtgagtgttc agatactcat taatatatgt gggcgttttc tgttgtattg tttgtcagtg
2401 tccttttgta aatgttgaag tgagttaggg t
//