GenBank-Updates@genbank.bio.net (05/25/91)
LOCUS SHPIGFIEX1 4131 bp ds-DNA MAM 25-MAY-1991
DEFINITION Ovine IGF-I gene for insulin-like growth factor-I exon 1 and exon
1A
ACCESSION X17229
KEYWORDS IGF1 gene; insulin-like growth factor i.
SOURCE Ovis aries DNA.
ORGANISM Ovis aries
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE 1 (bases 1 to 2714)
AUTHORS Dickson,M.C.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 1 to 4131)
AUTHORS Dickson,M.C., Saunders,J.C. and Gilmour,R.S.
TITLE The ovine insulin-like growth factor-I gene characterization,
expression and identification of a putative promoter
JOURNAL J. Mol. Endocrinol. 6, 17-31 (1991)
STANDARD full automatic
COMMENT From EMBL 26 entry OAIGFIEX1; dated 18-APR-1991.
FEATURES Location/Qualifiers
exon <2162..2224
/number=1
/note="alternatively spliced"
exon <4031..4045
/number=1
/note="alternatively spliced exon 1A"
CDS order(:2162..2224,X51357:855..1014,X51358:96..278,
X51403:456..515)
/product="insulin-like growth factor-I (1)"
/gene="IGF-I"
/label=IGF-I_orf
/codon_start=2162
CDS order(:4031..4045,X51357:855..1014,X51358:97..278,
X51403:456..515)
/product="insuline-like growth factor-I (2)"
/gene="IGF-I"
/label=IGF-I_orf
/codon_start=4031
intron 2225..>4131
/number=1
/note="alternatively spliced"
intron 4046..>4131
/number=1
/note="alternatively spliced"
BASE COUNT 1133 a 901 c 873 g 1224 t
ORIGIN
1 gggctgcagg tcgactctag aggatctttc aacccatgag acaatctgta tcttcaaagt
61 ccattagagg aggctgggct gggggcacaa aaggtgtgat gtgctgaagc tgaaggaaat
121 ttaaaaaaat aaataaaccc aaaccccaga tttttagtga acaattccta agttaaatgc
181 atgaagcggg gctcattaaa ggaggtcttg gattcttctc aaagtacagg ccttgcccca
241 cacctgaaga tacccccccc ccaccccgcc tacgtcttga tgatgtgtat ctcttcaggt
301 caaaacacat cccctgaaac ttcccaactt tgcatttcaa agctcctcat gacacacccc
361 tcctcctcca tcctggattc tcagtagttt cacttccctg tctttccaga gaaagtgtgc
421 acttttcata tttttaaaag cgcatcccac cacgtgacag tgctgttttc ctctctgcct
481 ctgccactta gttgaaaggc cctgtggtgt gtgtaactga gcacacagta ggagcgcact
541 cactgaatgc tgaatatagt gcactgttgg aatggcatca ctcctcgtgt ctaacttgtc
601 tttctcaaag gcaaaccctg ccccaagttt aatcacagag aaggcttgag tgaactcaac
661 cccctttcaa aaccaatcag gttttccttt gagggcaccc acctctgcaa cagcttcctg
721 gccatggcat aaagacctag acaagagttt caagcaaacc tttgttttta gtcgaagcat
781 caggatcact gtgtcccctg agaatcaaga gggagaaata caaggtccag gctactccca
841 ccattccaga aaaccatgcc ccaatagacc caggaaagtg ggatgtctaa cctgggcttt
901 tgcaatctta tttcataatc cactttctta tcgcctcctt cacaaaactg atgagaaatt
961 ggtacaaact ctatcgacaa agatcaacaa cttgatcctc aatggcaaag gcaagtatac
1021 attataaata gcaaaacagc tggcttggac catgttgctg gccactcatc cagctgagag
1081 atttgaatga catcataacc cttgagaggg tattgctagc cagctggtgt tatttagaat
1141 acacaaaaag gggggaaaga aaatgcactc acatgcacac acacacaaat acacacacac
1201 acacacaggt tcaagttatg cagaaaaata tgaacagtgg gaaaatcatt tgcctctcag
1261 atgcccttcc cctggtgtgg ggtgggagtc ggggtggggg gccaagcagc agaatagagg
1321 aaggaagaaa gagattcgat tttatttttt cagttggctt tacagctcag caaaatcttt
1381 ccctgtcgtg ggcaaaaagc atgagacagt gtcctgaggg gagccaatta caaagctgcc
1441 tgcccctttc caggttctag gaaatgagat cattcccctc acttggcaac caggacgagg
1501 ggtcatccca gcgccgtctt ccagtctagt taccccagac gtttgagggt taaaatcata
1561 gagtatgctt gagatgggtc tttttttcat ttcttgtttt ttaaattttg tgttggctct
1621 ggaatataaa attgctcgcc catcctccac gaatattcct ttcatacggg taaggtgtat
1681 tagcagatgt gtgtgtcttc atgcccggta gaaagttaat cagaggacag tacatcagga
1741 ttttaatgtc tgctcctctt gtcactaaca cacattcttt taagggaaaa aaatgcttct
1801 gtgctctagt tttaaaatgc aaaggtatga tgttatttgt caccatgccc aaaaaagtcc
1861 ttactcgata actttgccag aagagggaga gagagagaag gcaagcgttc ccccacgtgt
1921 ttcctgtcta cagtgtctgt gttttgtaga taaaatgtga ggattttctc taaatccctc
1981 ttctgtttgc taaatctcac tgtcactgct aaattcagag cagatagagc ctgcgcaatg
2041 gaataaagtc ctcaaaattg aaatgtgaca ttgctctcaa catctcccat ctccctggat
2101 ttctttttgc ctcattattc ctgctaacca attcatttcc agactttgca cttcagaagc
2161 aatgggaaaa atcagcagtc ttccaaccca attatttaag tgctgctttt gtgatttctt
2221 gaaggtaaat atttcttact ctttgaagtc attggggaat tttctttaaa ttgtgtactg
2281 cttgcttctg cttagaaatg ttcttcactt taagaatttt cattgtttcg gcactgggag
2341 ttatttataa attgctgaat atgcaattct gtgggatctg aaaaaatagc tccgggagat
2401 aaagtccttt gcacagatat ctgtatgagt aaaaactatt gcaaggtact tatgctaaat
2461 cctccacttc ttcaggcttg agtggtgtca ttatagaaga ttcctttaaa tcctgtctat
2521 ggttaagggc tatagggcat ggatatgaac ttttggattt tttttcgagg tcgagatgtt
2581 ttatttttaa gaccatgttc atgtgtatgt agggctgtgt ggtgtgtgtg tgtgcgtgtg
2641 tgttaactgg ccaggacttt tgattacaag gcatgccaca tacaaagagt tacgttttaa
2701 atgatattaa agcttttaaa tatgatcttt tggagctaag gtcccggaac tctctgcact
2761 tagccccaga gagtcaaagg tagagtgaag gttcatttgc tcttctgaaa aaagaactcc
2821 ttaagaactc ctgctgacct tgcagattcg gataatttaa acaaatgcac actgtatatg
2881 gaaagcggaa actttctagc aactgctatt ccaagttttt tcttttgaag aggactctca
2941 ggggcgaagt ttggacttgg ggtcttgtgt tgtaaaacac gggttttgta tttgggattg
3001 taaagtctct ttaggtgaat ttggctagcg ctgtcaatgc actgacttcg cctttccaat
3061 aactgcctag ttcaagtttc cgattctcag caaaattata tctttcaaga cttgtatttt
3121 tccaatttgc aagcattttt aagctgctgt actggctccc ccggatgcaa ttgcctgtgg
3181 gctcaattca tgatccgtcc ctaccgctta gtccaacact tatttgccgc tttccacact
3241 ccaccactag acgtttctta gtcaagtcag tggcttagga gttaagaata catccttgtc
3301 gggcacctga tcctgccgcc cttgagaagc caagatgcac actgcctacc ttgcttttaa
3361 aagaaatgaa gtcagtatac acatatgcta tgtggtctga gctggggatt ttgtctccct
3421 acttagagga tcctaaaagg ggctgtgtag tgttatctct gcattaatta caagtttgga
3481 aaactccaaa tgaactttcc atgctgtgta tgctgaactt ttcagaagta gagctagcta
3541 gccataagtt gttgcttttt cctgtacttg aagcaggaag tggtttcagg gagctacgtg
3601 gttctttcaa atgtatgtaa ttcaatgagt aaaggtggtg tctgccaggc agagctcaca
3661 agctgattgt actgtgagtc tcaagatatc tccaagtgtt tgagtcagag gaaagagggc
3721 acaggggagg actggagctt cggtccctgt ccaggacggc tacaataggc acaggatgga
3781 aatcagtggc ttgattggga ggaaaagatt gactcagatc ccagccgtgc aatttgttta
3841 ttgtctgaat ggacaaaagg cagtttaccc aggctcgtag catacctgcc tgggtgtcca
3901 aatgtaacta gatgctttca caaaccccac ccacaaagca gcacatgttt ttaagtcctc
3961 agttttctat tcacatcagt ctcataatac ccaccctgac ctgctgtaaa agatctggaa
4021 caaaacaaaa atggttacac ctacagtgag tattttctta tgactattgc cctcaaattt
4081 tcgtgggcat ttttattata aaccagacat ctggaaccaa ttgatattcc a
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