GenBank-Updates@genbank.bio.net (05/25/91)
LOCUS HUM7AH 2852 bp ss-mRNA PRI 25-MAY-1991
DEFINITION Human mRNA for cholesterol 7-alpha-hydroxylase
ACCESSION X56088
KEYWORDS cholesterol 7-alpha-hydroxylase; cholesterol 7-alpha-monooxygenase.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS Noshiro,M. and Okuda,K.
TITLE Molecular cloning and seqence analysis of cDNA encoding human
cholesterol 7 alpha-hydroxylase
JOURNAL FEBS Lett. 268, 137-140 (1990)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 2852)
AUTHORS Noshiro,M. and Okuda,K.
TITLE Molecular cloning and sequence analysis of cDNA encoding human
cholesterol 7-alpha-hydroxylase.
JOURNAL FEBS Lett. 1, 137-140 (1991)
STANDARD full automatic
COMMENT From EMBL 26 entry HS7AH; dated 24-APR-1991.
FEATURES Location/Qualifiers
mRNA 1..2852
/note="for cholesterol 7-alpha-hydroxylase"
CDS 40..1554
/EC_number="1.14.13.17"
/product="cholesterol 7-alpha-hydroxylase"
/codon_start=40
protein_bind 1348..1410
/bound_moiety="heme"
/note="putative"
polyA_signal 2836..2841
polyA_site 2852..2852
BASE COUNT 877 a 532 c 561 g 882 t
ORIGIN
1 agattttctt cctcagagat tttggcctag atttgcaaaa tgatgaccac atctttgatt
61 tgggggattg ctatagcagc atgctgttgt ctatggctta ttcttggaat taggagaagg
121 caaacgggtg aaccacctct agagaatgga ttaattccat acctgggctg tgctctgcaa
181 tttggtgcca atcctcttga gttcctcaga gcaaatcaaa ggaaacatgg tcatgttttt
241 acctgcaaac taatgggaaa atatgtccat ttcatcacaa atcccttgtc ataccataag
301 gtgttgtgcc acggaaaata ttttgattgg aaaaaatttc actttgctac ttctgcgaag
361 gcatttgggc acagaagcat tgacccgatg gatggaaata ccactgaaaa cataaacgac
421 actttcatca aaaccctgca gggccatgcc ttgaattccc tcacggaaag catgatggaa
481 aacctccaac gtatcatgag acctccagtc tcctctaact caaagaccgc tgcctgggtg
541 acagaaggga tgtattcttt ctgctaccga gtgatgtttg aagctgggta tttaactatc
601 tttggcagag atcttacaag gcgggacaca cagaaagcac atattctaaa caatcttgac
661 aacttcaagc aattcgacaa agtctttcca gccctggtag caggcctccc cattcacatg
721 ttcaggactg cgcacaatgc ccgggagaaa ctggcagaga gcttgaggca cgagaacctc
781 caaaagaggg aaagcatctc agaactgatc agcctgcgca tgtttctcaa tgacactttg
841 tccacctttg atgatctgga gaaggccaag acacacctcg tggtcctctg ggcatcgcaa
901 gcaaacacca ttccagcgac tttctggagt ttatttcaaa tgattaggaa cccagaagca
961 atgaaagcag ctactgaaga agtgaaaaga acattagaga atgctggtca aaaagtcagc
1021 ttggaaggca atcctatttg tttgagtcaa gcagaactga atgacctgcc agtattaaat
1081 agtataatca aggaatcgct gaggctttcc agtgcctccc tcaacatccg gacagctaag
1141 gaggatttca ctttgcacct tgaggacggt tcctacaaca tccgaaaaga tagcatcata
1201 gctctttacc cacagttaat gcacttagat ccagaaatct acccagaccc tttgactttt
1261 aaatatgata ggtatcttga tgaaaacggg aagacaaaga ctaccttcta ttgtaatgga
1321 ctcaagttaa agtattacta catgcccttt ggatcgggag ctacaatatg tcctggaaga
1381 ttgttcgcta tccacgaaat caagcaattt ttgattctga tgctttctta ttttgaattg
1441 gagcttatag agggccaagc taaatgtcca cctttggacc agtcccgggc aggcttgggc
1501 attttgccgc cattgaatga tattgaattt aaatataaat tcaagcattt gtgaatacat
1561 ggctggaata agaggacact agatgatatt acaggactgc agaacaccct caccacacag
1621 tccctttgga caaatgcatt tagtggtggt agaaatgatt caccaggtcc aatgttgttc
1681 accagtgctt gcttgtgaat cttaacattt tggtgacagt ttccagatgc tatcacagac
1741 tctgctagtg aaaagaacta gtttctagga gcacaataat ttgttttcat ttgtataagt
1801 ccatgaatgt tcatatagcc agggattgaa gtttattatt ttcaaaggaa aacaccttta
1861 ttttattttt tttcaaaatg aagatacaca ttacagccag gtgtggtagc aggcacctgt
1921 agtcttagct actcgagagg ccaaagaagg aggatggctt gagcccagga gttcaagacc
1981 agcctggaca gcttagtgag atcccgtctc cgaagaaaag atatgtattc taattggcag
2041 attgtttttt cctaaggaaa ctgctttatt tttataaaac tgcctgacaa ttatgaaaaa
2101 atgttcaaat tcacgttcta gtgaaactgc attatttgtt gactagatgg tggggttctt
2161 cgggtgtgat catatatcat aaaggatatt tcaaatgatt atgattagtt atgtctttta
2221 ataaaaagga aatatttttc aacttcttct atatccaaaa ttcagggctt taaacatgat
2281 tatcttgatt tcccaaaaac actaaaggtg gttttatttt cccttcatgt tttaacttat
2341 tgttgctgaa aactctatgt ccggctttaa ctatcttctc tatattttta tttcattcac
2401 attaatgaga agagttttct cagagattaa aaaaggtagt ttttctgtca ttgttaaata
2461 cacattatca ctgaaaaaat gtagctttta tgatgtatgt tttaaagtta aaactggatg
2521 gaaatagcca tttggaagct ttggttatga aacatgtgga gtgtattaag tgcagcttga
2581 cattatgttt tatttaaatg ctttttatcg ctaaatgact tgcagatgaa aaaaactaag
2641 gtgactcgag tgtttaaatg cctgtgtaca acaatgcttt gataaaatat tttaaggtat
2701 gagttatcag ctctatgtca attgatattt ctgtgtagta tttatattta aattatattt
2761 acctttttgc ttattttaca aatattaaga aaatattcta acatttgata attttgaaat
2821 gattcatctt tcagaaataa aagtatgaat ct
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