GenBank-Updates@genbank.bio.net (05/25/91)
LOCUS CXBCOXB4 7395 bp ss-mRNA VRL 25-MAY-1991
DEFINITION Coxsackie virus B4 complete genome
ACCESSION X05690
KEYWORDS complete genome; polymerase; protease.
SOURCE Coxsackievirus B4 RNA.
ORGANISM Coxsackievirus B4
Viridae; ss-RNA nonenveloped viruses; Isometric ss-RNA viruses;
Picornaviridae; Enterovirus.
REFERENCE 1 (bases 1 to 7395)
AUTHORS Jenkins,O., Booth,J.D., Minor,P.D. and Almond,J.W.
TITLE The Complete Nucleotide Sequence of Coxsackievirus B4 and Its
Comparison to Other Members of the Picornaviridae
JOURNAL J. Gen. Virol. 68, 1835-1848 (1987)
STANDARD full automatic
REFERENCE 2 (bases 1 to 7395)
AUTHORS Jenkins,O.
JOURNAL Unpublished (1989)
STANDARD full automatic
COMMENT SWISS-PROT; P08292; POLG$COXB4.
*source: strain=J.V.B. Benschoten;
Data kindly reviewed (11-FEB-88) by Jenkins O.
From EMBL 26 entry PICOXB4; dated 26-APR-1991.
FEATURES Location/Qualifiers
misc_feature 744..949
/note="VP 4 (AA 1-69) (949 is 2nd base in codon)"
CDS 744..7292
/product="polyprotein CB4"
/codon_start=744
misc_feature 950..1732
/note="VP 2 (AA 70-330) (950 is 3rd base in codon) (1732
is 2nd base in codon)"
old_sequence 1043..1045
/note="cgt was cct in [1]"
/citation=[1]
old_sequence 1171..1173
/note="agt was act in [1]"
/citation=[1]
old_sequence 1217..1219
/note="ggg was gcg in [1]"
/citation=[1]
misc_feature 1733..2446
/note="VP 3 (AA 331-568) (1733 is 3rd base in codon) (2446
is 2nd base in codon)"
misc_feature 2447..3298
/note="VP 1 (AA 569-852) (2447 is 3rd base in codon) (3298
is 2nd base in codon)"
misc_feature 3299..3739
/note="P2-A (AA 853-999) (3299 is 3rd base in codon) (3739
is 2nd base in codon)"
misc_feature 3740..4036
/note="P2-B (AA 1000-1098) (3740 is 3rd base in codon)
(4036 is 2nd base in codon)"
misc_feature 4037..5023
/note="P2-C (AA 1099-1427) (4037 is 3rd base in codon)
(5023 is 2nd base in codon)"
old_sequence 4233..4235
/note="ggc was gcc in [1]"
/citation=[1]
misc_feature 5024..5290
/note="P 3-A (AA 1428-1516) (5024 is 3rd base in codon)
(5290 is 2nd base in codon)"
old_sequence 5117..5119
/note="agt was act in [1]"
/citation=[1]
misc_feature 5291..5356
/note="V Pg (AA 1517-1538) (5291 is 3rd base in codon)
(5356 is 2nd base in codon)"
misc_feature 5357..5905
/note="protease (P3-C) (AA 1538-1721) (5357 is 3rd base in
codon) (5905 is 2nd base in codon)"
old_sequence 5875..5877
/note="ggc was gcc in [1]"
/citation=[1]
misc_feature 5906..7292
/note="polymerase (P3-D) (AA 1722-2183) (5906 is 3rd base
in codon)"
old_sequence 6032..6034
/note="cct was cgt in [1]"
/citation=[1]
old_sequence 6351..6353
/note="gga was gca in [1]"
/citation=[1]
old_sequence 6448..6450
/note="tga was tca in [1]"
/citation=[1]
polyA_site 7395..7395
BASE COUNT 2093 a 1693 c 1838 g 1771 t
ORIGIN
1 ttaaaacagc ctgtgggttg tacccaccca cagggcccaa tgggcgctag cacactggta
61 ttccggtacc tttgtgcgcc tgttttataa ccccccccca gttcgcaact tagaagcaaa
121 gaaacaatgg tcaattactg acgcagcaac ccagctgtgt tttggccaag tacttctgtg
181 tccccggact gagtatcaat aagctgcttg cgcggctgaa ggagaaaccg ttcgttaccc
241 ggccaactac ttcgagaagc ctagtaacgc catgaacgtt gaggagtgtt tcgctcagca
301 cttcccccgt gtagttcagg tcgatgagtc accgcgttcc ccacgggtga ccgtggcggt
361 ggctgcgttg gcggcctgcc tgtggggcaa cccgcaggac gctctgatac agacatggtg
421 tgaagagcct attgagctag ttggtagtcc tccggcccct gaatgcggct aatcctaact
481 gcggagcaca cgttcgcaag ccagcgagtg gtgtgtcgta acgggcaact ctgcagcgga
541 accgagtact ttgggtgtcc gtgtttcctt ttattcttac cttggctgct tatggtgaca
601 attgaaagat tgttaccata tagctattgg attggccatc cagtgtcaaa tagagcaatc
661 atatatctgt ttgttggttt cgttcccttg gactacagaa atcttaaaac tctttatttc
721 atattgagac tcaatacgat aaaatgggag cacaggtgtc aacacaaaag acaggggcac
781 acgagactag tttgagcgcc agtggaaact cgattattca ttacaccaac ataaactatt
841 acaaggatgc tgcttcaaat tcggccaata ggcaagattt tacacaagac cctagtaaat
901 tcacagaacc ggtaaaggat gtgatgataa agtcgctgcc agcgctcaat tccccgactg
961 tagaggagtg cggatatagc gacagagtta gatcaataac actcgggaac tcgactataa
1021 cgacacaaga gtgtgcaaac gtcgtggtgg ggtatggcgt ctggcccgat tatcttagcg
1081 acgaagaggc aacagcggaa gaccagccca cccaacctga tgtggcaacg tgtaggtttt
1141 acacgttgaa ttcagtgaaa tgggagatgc agtcagcggg gtggtggtgg aagttcccag
1201 atgcattgtc agaaatgggg ctctttgggc agaatatgca atatcactac ctaggcagat
1261 cagggtacac aattcatgtg caatgcaacg catccaaatt ccaccaaggt tgtctgcttg
1321 tggtgtgtgt gcctgaggct gagatgggat gtaccaatgc agaaaacgca cccgcgtatg
1381 gtgatttgtg tggaggagag acagcaaaga gtttcgaaca gaatgcagcc acaggtaaga
1441 cagctgtgca gacggctgtg tgcaatgcgg gtatgggtgt gggggttggt aacttgacta
1501 tataccctca ccaatggatt aatttaagaa caaacaatag tgccaccata gtgatgccat
1561 acattaatag cgtcccaatg gacaacatgt tcaggcataa taactttaca ttaatgataa
1621 taccctttgc accgttggac tacgttacgg gagcgtcctc ttacatccct atcacagtga
1681 cagttgcccc tatgagcgct gagtacaatg gtttgcgtct agctggtcat caaggcttac
1741 caactatgct tacaccaggc agcacgcagt ttttgacgtc agatgatttt caatcaccat
1801 cagctatgcc acagtttgat gtgaccccag agatgaacat tccagggcaa gtgaggaacc
1861 tgatggaaat tgcggaagtt gattctgtgg taccaatcaa taacttgaaa gctaatctga
1921 tgacgatgga ggcttaccgg gtgcaggtta ggtccactga cgagatggga ggacagatat
1981 ttggcttccc cttacagcca ggggcatcaa gcgtgttaca aagaacacta ctgggagaga
2041 tattaaatta ctacactcat tggtcaggga gcctcaagtt aacatttgtg ttctgtgggt
2101 cggcaatggc aactggcaaa ttcttactag catactcacc acctggagca ggggcaccag
2161 acagcaggaa gaacgctatg ttagggaccc acgtcatatg ggacgttgga ctgcaatcca
2221 gctgtgtgct ctgtgtaccg tggatcagcc agacgcacta caggtatgtt gttgatgaca
2281 agtacacggc tagtggtttc atttcgtgct ggtaccaaac taatgtcata gtcccagctg
2341 aagctcagaa atcgtgctac ataatgtgct ttgtgtcagc atgcaacgat ttctctgtac
2401 gcatgttgag ggacacgcaa ttcattaagc aaacaaactt ttatcaggga ccaacagaag
2461 agtccgtgga gagagcaatg gggagagttg cagacacgat tgcccgcggc ccatcgaact
2521 ctgagcaaat cccagctctg acagctgtgg agactggaca tacttcccag gtggatccaa
2581 gtgacacgat gcaaacaaga catgtgcata actaccactc cagatcagaa tcatctatag
2641 aaaacttcct gtgcagatct gcttgcgtaa tttatataaa atactccagt gctgaatcaa
2701 acaacctgaa gcggtatgcg gagtgggtta tcaacacaag gcaggtggct caactaaggc
2761 gaaagatgga aatgttcact tatattcggt gcgacatgga gcttaccttt gtgattacca
2821 gccatcagga gatgtccacc gccactaact cagatgttcc agtgcagaca caccaaataa
2881 tgtacgtgcc acctggcggc cctgtaccaa cgtcagtcaa cgactacgtg tggcaaacat
2941 ccaccaaccc cagcatcttt tggacagagg gcaatgcacc accaaggatg tccataccgt
3001 tcatgagtat tggcaatgct tacaccatgt tttatgacgg gtggtcaaac ttctccagag
3061 acggcatata tggatataat tcattaaaca acatggggac catatatgcg cgccatgtta
3121 atgattctag cccaggggga ctgaccagca ccatccgcat ctacttcaaa cccaaacacg
3181 tcaaagcata tgtgccacgc cccccccgtt tgtgtcaata caagaaagcc aagagtgtga
3241 actttgatgt tgaggccgtt acagcggagc gtgcaagctt gataaccaca ggcccctatg
3301 gacatcaatc aggggccgtg tatgtgggca attacaaggt agtcaatagg cacttggcca
3361 cgcacgtgga ttggcaaaat tgcgtgtggg aggattataa tagagacctt ctagtgagta
3421 ctaccacggc ccacgggtgc gacaccattg ccagatgcca atgcacaaca ggtgtgtact
3481 tttgcgcctc caagagcaaa cactacccag ttagctttga aggaccaggt ttggtggaag
3541 tccaagaaag tgaatattac ccaaaaagat accagtctca tgtgttgctt gctacagggt
3601 tctccgaacc aggagattgc ggtggaattc tcaggtgcga acacggcgtc atcggtcttg
3661 tcaccatggg tggtgaaggc gtggttggtt tcgccgatgt ccgtgacctg ttgtggttgg
3721 aagatgatgc aatggaacag ggagtgaaag attacgttga gcaacttggt aatgcttttg
3781 gctcaggatt caccaaccag atatgcgagc aggttaacct cctaaaagaa tcactagtag
3841 gtcaggactc aatcttggag aagtcactca aagccctagt taagatcatc tctgccctgg
3901 tgattgtagt aaggaatcat gatgacctga tcacagttac agctacactc gcccttattg
3961 gctgcacctc gtctccgtgg cgatggctta agcacaaggt gtcccaatat tacggaatac
4021 ccatggctga acggcagaac aacgggtggc taaagaaatt tacagagatg actaacgcat
4081 gcaaagggat ggagtggata gccgtcaaga ttcagaaatt tatagaatgg ctcaaggtta
4141 agattttgcc agaagtcaag gaaaagcatg aattcctaag tagactcaaa cagctcccac
4201 tcttggagag tcagattgcc accattgaac aaagtgcacc ctctcaaagt gaccaggaac
4261 agctgttctc aaatgtccag tacttcgctc actattgcag aaagtacgca ccgctctacg
4321 ctgcagaagc caagagggtg ttttcccttg aaaaaaaaat gagcaattac atacagttca
4381 agtccaaatg ccgtattgaa cctgtatgct tgcttttgca tggtagccca ggagcgggga
4441 agtcagttgc taccaactta attgggcggt cattagctga aaagttaaac agttcagtgt
4501 actccttacc accagaccca gaccatttcg atggctacaa acaacaagcc gtcgtaatta
4561 tggacgatct atgccaaaac ccggatggca aggacgtgtc tttgttctgc caaatggtgt
4621 ctagtgtaga ctttgtacca ccaatggctg cactggagga aaaaggtatc ttgttcacct
4681 ccccttttgt cctggcctca accaatgctg ggtccatcaa cgcgccgaca gtctcagaca
4741 gccgggctct ggcaagaagg ttccattttg acatgaatat tgaagttatc tccatgtaca
4801 gccagaatgg caagatcaac atgcccatgt cagtcaagac gtgtgatgaa gagtgttgcc
4861 cagtcaattt caagagatgc tgccctctag tgtgtggaaa ggctatccag tttatcgata
4921 gaaagactca agtgaggtac tccctagata tgctagtcac ggagatgttt agggaataca
4981 accacaggca cagtgtcggg gcgacccttg aggcgctatt ccaaggcccg ccagtgtaca
5041 gagaaattaa aattagtgtc acacctgaaa ccccaccacc accagtaatc gcagacttgt
5101 tgaagtcagt ggacaggcag gctattagag agtactgtaa ggagaaggga tggctagttc
5161 ctgagatcga ttctattctc caaattgaga agcatgtcag tagagcattt atctgcctcc
5221 aagcactgac aactttcgtg tctgtggccg gaattattta tatcatttac aaactgtttg
5281 cagggttcca gggtgcatat acggggatgc ctaaccaaaa acctaaagtg cctacactaa
5341 ggcaggctaa agtgcagggt cccgcttttg agttcgctgt ggccatgatg aagaggaact
5401 ccagtacggt gaaaacagag tatggcgagt tcaccatgtt aggcatctat gacaggtggg
5461 ctgtcctacc acgccacgct aaacccgggc cgactattct tatgaatgac caggaggtcg
5521 gtgtgctgga tgccaaggaa ttaatagaca gagatggtac aaatctggag ctgacactac
5581 tgaaactcaa ccggaatgag aaattcaggg acatcagagg ttttctagcc aaggaggaag
5641 tggaggttaa tgaagctgtc ctagcaatca acactagcaa atttccaaac atgtacatcc
5701 ccgtaggcag ggtcacagac tatggcttcc taaacctagg tggtactccc acaaagagaa
5761 tgctcatgta caacttccct acaagggctg gacagtgtgg cggtgttctc atgtccactg
5821 gcaaggtgct agggatccac gttggtggga atggtcacca gggtttctca gcaggcctcc
5881 ttaagcacta ctttaatgat gagcaggggg agatcgagtt catcgaaagc tcgaaagatg
5941 caggtttccc agtcatcaat acaccaagta gaactaagct agaaccaagc gtcttccatc
6001 acgtctttga aggaaacaag gaaccagcag tcctcaggaa cggcgacccg cgccttaaag
6061 tcaactttga ggaggctata tttttcaaat acataggaaa cgtcaacaca catgtggacg
6121 agtacatgct agaagctgtg gatcactatg cagggcaatt ggccactctt gacattaaca
6181 ctgagccaat gaaactggaa gatgcagtgt acggcacgga agggctagag gctcttgatt
6241 taacaacaag tgcggggtac ccatatgttg cattaggcat taagaagagg gacatcctat
6301 ccaaaaagac caaagacctg accaaattga aggaatgtat ggacaagtac ggattaaact
6361 tgccgatggt gacatacgtg aaggatgagc ttagatcagc agagaaggtg gccaaaggga
6421 aatctagact cattgaagca tccagcttga acgactctgt tgcgatgagg caaacatttg
6481 gtaatttgta caaggcattc cacttaaacc cggggattgt aacgggcagt gcagtcgggt
6541 gcgatccaga cgttttctgg agtaaaatac ctgtgatgct agacggacac cttatagcct
6601 tcgactactc cggttatgac gccagtctga gccccgtgtg gtttgcttgt ctaaagttgc
6661 tgcttgaaaa actcgggtac acacataaag agacaaacta cattgactac ttatgcaact
6721 cccaccacct atacagagac aaacactact ttgtacgtgg cggtatgccc tcagggtgct
6781 ctggtaccag catcttcaac tcaatgatca ataacatcat tatcaggacc ttaatgttga
6841 aggtgtacaa aggtattgac ttggatcaat tcaggatgat tgcatatggt gatgatgtga
6901 ttgcatcata tccttggccc atagacgcct ctctgctcgc tgaagctggt aaagactacg
6961 ggctaatcat gacaccagcg gataaaggag agtgttttaa cgaagtcacc tggactaatg
7021 tcacctttct aaagaggtat tttagagcag atgaacaata ccctttcttg gttcacccag
7081 tgatgcccat gaaagacatc cacgagtcta tcaggtggac caaagatcca aagaacactc
7141 aagatcatgt gcgctccctg tgcttattgg cttggcacaa tggagagcac gaatatgagg
7201 agttcatcca aaagatcaga agcgtcccag ttgggcgctg cttgactctg cccgcgtttt
7261 cgaccctacg taggaaatgg ttggattcct tttaaattag agacaatttg aaacaattta
7321 aattggctta accctactgc actaaccgaa ctagataacg gtgcagtagg ggtaaattct
7381 ccgcgttcgg tgcgg
//