GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMFGFRFL 2662 bp ss-mRNA PRI 26-MAY-1991
DEFINITION Human flg mRNA for fibroblast growth factor receptor-FLG
ACCESSION X52833
KEYWORDS cell surface glycoprotein; fibroblast growth factor receptor;
tyrosine kinase.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2662)
AUTHORS Dionne,C.A.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Dionne,C.A., Crumley,G.R., Bellot,F., Kaplow,J.M., Searfoss,G.,
Ruta,M., Burgess,W.H., Jaye,M. and Schlessinger,J.
TITLE Cloning and expression of two distinct high-affinity receptors
cross-reacting with acidic and basic fibroblast growth factors
JOURNAL EMBO J. 9, 2685-2692 (1990)
STANDARD full staff_review
COMMENT *source: cell line=HUVEC; library=lambda gt11;
From EMBL entry HSFGFRFL; dated 25-OCT-1990.
FEATURES Location/Qualifiers
CDS 88..2553
/note="fibroblast growth factor receptor-FLG precursor"
/codon_start=88
CDS 88..150
/note="signal peptide"
/codon_start=88
CDS 151..2553
/note="mature fibroblast growth factor receptor -FLG"
/codon_start=151
BASE COUNT 613 a 787 c 740 g 522 t
ORIGIN
1 tcagtttgaa aaggaggatc gagctcactc gtggagtatc catggagatg tggagccttg
61 tcaccaacct ctaactgcag aactgggatg tggagctgga agtgcctcct cttctgggct
121 gtgctggtca cagccacact ctgcaccgct aggccgtccc cgaccttgcc tgaacaagcc
181 cagccctggg gagcccctgt ggaagtggag tccttcctgg tccaccccgg tgacctgctg
241 cagcttcgct gtcggctgcg ggacgatgtg cagagcatca actggctgcg ggacggggtg
301 cagctggcgg aaagcaaccg cacccgcatc acaggggagg aggtggaggt gcaggactcc
361 gtgcccgcag actccggcct ctatgcttgc gtaaccagca gcccctcggg cagtgacacc
421 acctacttct ccgtcaatgt ttcagatgct ctcccctcct cggaggatga tgatgatgat
481 gatgactcct cttcagagga gaaagaaaca gataacacca aaccaaaccg tatgcccgta
541 gctccatatt ggacatcccc agaaaagatg gaaaagaaat tgcatgcagt gccggctgcc
601 aagacagtga agttcaaatg cccttccagt gggaccccaa accccacact gcgctggttg
661 aaaaatggca aagaattcaa acctgaccac agaattggag gctacaaggt ccgttatgcc
721 acctggagca tcataatgga ctctgtggtg ccctctgaca agggcaacta cacctgcatt
781 gtggagaatg agtacggcag catcaaccac acataccagc tggatgtcgt ggagcggtcc
841 cctcaccgcc ccatcctgca agcagggttg cccgccaaca aaacagtggc cctgggtagc
901 aacgtggagt tcatgtgtaa ggtgtacagt gacccgcagc cgcacatcca gtggctaaag
961 cacatcgagg tgaatgggag caagattggc ccagacaacc tgccttatgt ccagatcttg
1021 aagactgctg gagttaatac caccgacaaa gagatggagg tgcttcactt aagaaatgtc
1081 tcctttgagg acgcagggga gtatacgtgc ttggcgggta actctatcgg actctcccat
1141 cactctgcat ggttgaccgt tctggaagcc ctggaagaga ggccggcagt gatgacctcg
1201 cccctgtacc tggagatcat catctattgc acaggggcct tcctcatctc ctgcatggtg
1261 gggtcggtca tcgtctacaa gatgaagagt ggtaccaaga agagtgactt ccacagccag
1321 atggctgtgc acaagctggc caagagcatc cctctgcgca gacaggtaac agtgtctgct
1381 gactccagtg catccatgaa ctctggggtt cttctggttc ggccatcacg gctctcctcc
1441 agtgggactc ccatgctagc aggggtctct gagtatgagc ttcccgaaga ccctcgctgg
1501 gagctgcctc gggacagact ggtcttaggc aaacccctgg gagagggctg ctttgggcag
1561 gtggtgttgg cagaggctat cgggctggac aaggacaaac ccaaccgtgt gaccaaagtg
1621 gctgtgaaga tgttgaagtc ggacgcaaca gagaaagact tgtcagacct gatctcagaa
1681 atggagatga tgaagatgat cgggaagcat aagaatatca tcaacctgct gggggcctgc
1741 acgcaggatg gtcccttgta tgtcatcgtg gagtatgcct ccaagggcaa cctgcgggag
1801 tacctgcagg cccggaggcc cccagggctg gaatactgct acaaccccag ccacaaccca
1861 gaggagcagc tctcctccaa ggacctggtg tcctgcgcct accaggtggc ccgaggcatg
1921 gagtatctgg cctccaagaa gtgcatacac cgagacctgg cagccaggaa tgtcctggtg
1981 acagaggaca atgtgatgaa gatagcagac tttggcctcg cacgggacat tcaccacatc
2041 gactactata aaaagacaac caacggccga ctgcctgtga agtggatggc acccgaggca
2101 ttatttgacc ggatctacac ccaccagagt gatgtgtggt ctttcggggt gctcctgtgg
2161 gagatcttca ctctgggcgg ctccccatac cccggtgtgc ctgtggagga acttttcaag
2221 ctgctgaagg agggtcaccg catggacaag cccagtaact gcaccaacga gctgtacatg
2281 atgatgcggg actgctggca tgcagtgccc tcacagagac ccaccttcaa gcagctggtg
2341 gaagacctgg accgcatcgt ggccttgacc tccaaccagg agtacctgga cctgtccatg
2401 cccctggacc agtactcccc cagctttccc gacacccgga gctctacgtg ctcctcaggg
2461 gaggattccg tcttctctca tgagccgctg cccgaggagc cctgcctgcc ccgacaccca
2521 gcccagcttg ccaatggcgg actcaaacgc cgctgactgc cacccacacg ccctccccag
2581 actccaccgt cagctgtaac cctcacccac agcccctgcc tgggcccacc acctgtccgt
2641 ccctgtcccc tttcctgctg gg
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