GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMAANP 3803 bp ss-mRNA PRI 26-MAY-1991
DEFINITION Human mRNA for natriuretic peptide receptor (ANP-A receptor)
ACCESSION X15357
KEYWORDS ANP-A receptor; glycoprotein; natriuretic peptide receptor;
receptor; transmembrane protein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3803)
AUTHORS Lowe,D.G., Chang,M.S., Hellmiss,R., Chen,E., Singh,S., Garbers,D.L.
and Goeddel,D.V.
TITLE Human atrial natriuretic receptor defines a new paradigm for second
messenger signal transduction
JOURNAL EMBO J. 8, 1377-1384 (1989)
STANDARD full automatic
COMMENT SWISS-PROT; P16066; ANPA$HUMAN.
*source: tissue=kidney; library=lambda gt10;
From EMBL entry HSAANP; dated 13-FEB-1990.
FEATURES Location/Qualifiers
CDS 44..3226
/note="ANP-A receptor preprotein (AA -32 to 1029)"
/codon_start=44
CDS 44..139
/note="signal peptide (AA -32 to -1)"
/codon_start=44
CDS 140..3226
/note="ANP-A receptor (AA 1 - 1029)"
/codon_start=140
misc_feature 3783..3788
/note="pot. polyA signal"
polyA_site 3803..3803
/note="polyA site"
BASE COUNT 775 a 1128 c 1165 g 735 t
ORIGIN
1 ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg
61 ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct
121 gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac
181 ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt
241 gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga
301 aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg
361 ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg
421 gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt
481 cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg
541 ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta
601 cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg
661 ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag
721 ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag
781 ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga
841 ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc
901 tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt
961 tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct
1021 gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt
1081 gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga
1141 gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa
1201 ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac
1261 agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta
1321 caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg
1381 gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca
1441 agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat
1501 tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga
1561 gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag
1621 tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac
1681 agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt
1741 gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca
1801 tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc
1861 caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa
1921 tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg
1981 catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg
2041 cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga
2101 cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct
2161 cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg
2221 gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct
2281 gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc
2341 cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga
2401 ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag
2461 ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa
2521 tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga
2581 ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac
2641 ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac
2701 agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac
2761 ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc
2821 ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc
2881 ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca
2941 ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg
3001 actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga
3061 gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga
3121 gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt
3181 tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc
3241 tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag
3301 cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc
3361 tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca
3421 gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc
3481 acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc
3541 cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga
3601 aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg
3661 cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag
3721 aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga
3781 caattaaaat ctttattcca gtg
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