GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMABP280 8368 bp ss-mRNA PRI 26-MAY-1991
DEFINITION Human mRNA for actin-binding protein (filamin) (ABP-280)
ACCESSION X53416
KEYWORDS actin-binding protein; filament formation; phosphoprotein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 8368)
AUTHORS Gorlin,J.B.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 8368)
AUTHORS Gorlin,J.B., Yamin,R., Egan,S., Stewart,M., Stossel,T.P.,
Kwiatkowski,D.J. and Hartwig,J.H.
TITLE Human Endothelial Actin-Binding Protein (ABP-280, Nonmuscle
Filamin): A Molecular Leaf Spring
JOURNAL J. Cell Biol. 111, 1089-1105 (1990)
STANDARD full automatic
COMMENT *source: cell line=HUVEC **map: map position=distal (telomeric) to
Xq2.4; chromosome=X
From EMBL entry HSABP280; dated 14-JAN-1991.
FEATURES Location/Qualifiers
CDS 173..8113
/note="actin-binding protein"
/codon_start=173
BASE COUNT 1742 a 2582 c 2625 g 1419 t
ORIGIN
1 gcgatccggg cgccaccccg cggtcatcgg tcaccggtcg ctctcaggaa cagcagcgca
61 acctctgctc cctgcctcgc ctcccgcgcg cctaggtgcc tgcgacttta attaaagggc
121 cgtcccctcg ccgaggctgc agcaccgccc ccccggcttc tcgcgcctca aaatgagtag
181 ctcccactct cgggcgggcc agagcgcagc aggcgcggct ccgggcggcg gcgtcgacac
241 gcgggacgcc gagatgccgg ccaccgagaa ggacctggcg gaggacgcgc cgtggaagaa
301 gatccagcag aacactttca cgcgctggtg caacgagcac ctgaagtgcg tgagcaagcg
361 catcgccaac ctgcagacgg acctgagcga cgggctgcgg cttatcgcgc tgttggaggt
421 gctcagccag aagaagatgc accgcaagca caaccagcgg cccactttcc gccaaatgca
481 gcttgagaac gtgtcggtgg cgctcgagtt cctggaccgc gagagcatca aactggtgtc
541 catcgacagc aaggccatcg tggacgggaa cctgaagctg atcctgggcc tcatctggac
601 cctgatcctg cactactcca tctccatgcc catgtgggac gaggaggagg atgaggaggc
661 caagaagcag acccccaagc agaggctcct gggctggatc cagaacaagc tgccgcagct
721 gcccatcacc aacttcagcc gggactggca gagcggccgg gccctgggcg ccctggtgga
781 cagctgtgcc ccgggcctgt gtcctgactg ggactcttgg gacgccagca agcccgttac
841 caatgcgcga gaggccatgc agcaggcgga tgactggctg ggcatccccc aggtgatcac
901 ccccgaggag attgtggacc ccaacgtgga cgagcactct gtcatgacct acctgtccca
961 gttccccaag gccaagctga agccaggggc tcccttgcgc cccaaactga acccgaagaa
1021 agcccgtgcc tacgggccag gcatcgagcc cacaggcaac atggtgaaga agcgggcaga
1081 gttcactgtg gagaccagaa gtgctggcca gggagaggtg ctggtgtacg tggaggaccc
1141 ggccggacac caggaggagg caaaagtgac cgccaataac gacaagaacc gcaccttctc
1201 cgtctggtac gtccccgagg tgacggggac tcataaggtt actgtgctct ttgctggcca
1261 gcacatcgcc aagagcccct tcgaggtgta cgtggataag tcacagggtg acgccagcaa
1321 agtgacagcc caaggtcccg gcctggagcc cagtggcaac atcgccaaca agaccaccta
1381 ctttgagatc tttacggcag gagctggcac gggcgaggtc gaggttgtga tccaggaccc
1441 catgggacag aagggcacgg tagagcctca gctggaggcc cggggcgaca gcacataccg
1501 ctgcagctac cagcccacca tggagggcgt ccacaccgtg cacgtcacgt ttgccggcgt
1561 gcccatccct cgcagcccct acactgtcac tgttggccaa gcctgtaacc cgagtgcctg
1621 ccgggcggtt ggccggggcc tccagcccaa gggtgtgcgg gtgaaggaga cagctgactt
1681 caaggtgtac acaaagggcg ctggcagtgg ggagctgaag gtcaccgtga agggccccaa
1741 gggagaggag cgcgtgaagc agaaggacct gggggatggc gtgtatggct tcgagtatta
1801 ccccatggtc cctggaacct atatcgtcac catcacgtgg ggtggtcaga acatcgggcg
1861 cagtcccttc gaagtgaagg tgggcaccga gtgtggcaat cagaaggtac gggcctgggg
1921 ccctgggctg gagggcggcg tcgttggcaa gtcagcagac tttgtggtgg aggctatcgg
1981 ggacgacgtg ggcacgctgg gcttctcggt ggaagggcca tcgcaggcta agatcgaatg
2041 tgacgacaag ggcgacggct cctgtgatgt gcgctactgg ccgcaggagg ctggcgagta
2101 tgccgttcac gtgctgtgca acagcgaaga catccgcctc agccccttca tggctgacat
2161 ccgtgacgcg ccccaggact tccacccaga cagggtgaag gcacgtgggc ctggattgga
2221 gaagacaggt gtggccgtca acaagccagc agagttcaca gtggatgcca agcacggtgg
2281 caaggcccca cttcgggtcc aagtccagga caatgaaggc tgccctgtgg aggcgttggt
2341 caaggacaac ggcaatggca cttacagctg ctcctacgtg cccaggaagc cggtgaagca
2401 cacagccatg gtgtcctggg gaggcgtcag catccccaac agccccttca gggtgaatgt
2461 gggagctggc agccacccca acaaggtcaa agtatacggc cccggagtag ccaagacagg
2521 gctcaaggcc cacgagccca cctacttcac tgtggactgc gccgaggctg gccaggggga
2581 cgtcagcatc ggcatcaagt gtgcccctgg agtggtaggc cccgccgaag ctgacatcga
2641 cttcgacatc atccgcaatg acaatgacac cttcacggtc aagtacacgc cccggggggc
2701 tggcagctac accattatgg tcctctttgc tgaccaggcc acgcccacca gccccatccg
2761 agtcaaggtg gagccctctc atgacgccag taaggtgaag gccgagggcc ctggcctcag
2821 tcgcactggt gtcgagcttg gcaagcccac ccacttcaca gtaaatgcca aagctgctgg
2881 caaaggcaag ctggacgtcc agttctcagg actcaccaag ggggatgcag tgcgagatgt
2941 ggacatcatc gaccaccatg acaacaccta cacagtcaag tacacgcctg tccagcaggg
3001 tccagtaggc gtcaatgtca cttatggagg ggatcccatc cctaagagcc ctttctcagt
3061 ggcagtatct ccaagcctgg acctcagcaa gatcaaggtg tctggcctgg gagagaaggt
3121 ggacgttggc aaagaccagg agttcacagt caaatcaaag ggtgctggtg gtcaaggcaa
3181 agtggcatcc aagattgtgg gcccctcggg tgcagcggtg ccctgcaagg tggagccagg
3241 cctgggggct gacaacagtg tggtgcgctt cctgccccgt gaggaagggc cctatgaggt
3301 ggaggtgacc tatgacggcg tgcccgtgcc tggcagcccc tttcctctgg aagctgtggc
3361 ccccaccaag cctagcaagg tgaaggcgtt tgggccgggg ctgcagggag gcagtgcggg
3421 ctcccccgcc cgcttcacca tcgacaccaa gggcgccggc acaggtggcc tgggcctgac
3481 ggtggagggc ccctgtgagg cgcagctcga gtgcttggac aatggggatg gcacatgttc
3541 cgtgtcctac gtgcccaccg agcccgggga ctacaacatc aacatcctct tcgctgacac
3601 ccacatccct ggctccccat tcaaggccca cgtggttccc tgctttgacg catccaaagt
3661 caagtgctca ggccccgggc tggagcgggc caccgctggg gaggtgggcc aattccaagt
3721 ggactgctcg agcgcgggca gcgcggagct gaccattgag atctgctcgg aggcggggct
3781 tccggccgag gtgtacatcc aggaccacgg tgatggcacg cacaccatta cctacattcc
3841 cctctgcccc ggggcctaca ccgtcaccat caagtacggc ggccagcccg tgcccaactt
3901 ccccagcaag ctgcaggtgg aacctgcggt ggacacttcc ggtgtccagt gctatgggcc
3961 tggtattgag ggccagggtg tcttccgtga ggccaccact gagttcagtg tggacgcccg
4021 ggctctgaca cagaccggag ggccgcacgt caaggcccgt gtggccaacc cctcaggcaa
4081 cctgacggag acctacgttc aggaccgtgg cgatggcatg tacaaagtgg agtacacgcc
4141 ttacgaggag ggactgcact ccgtggacgt gacctatgac ggcagtcccg tgcccagcag
4201 ccccttccag gtgcccgtga ccgagggctg cgacccctcc cgggtgcgtg tccacgggcc
4261 aggcatccaa agtggcacca ccaacaagcc caacaagttc actgtggaga ccaggggagc
4321 tggcacgggc ggcctgggcc tggctgtaga gggcccctcc gaggccaaga tgtcctgcat
4381 ggataacaag gacggcagct gctcggtcga gtacatccct tatgaggctg gcacctacag
4441 cctcaacgtc acctatggtg gccatcaagt gccaggcagt cctttcaagg tccctgtgca
4501 tgatgtgaca gatgcgtcca aggtcaagtg ctctgggccc ggcctgagcc caggcatggt
4561 tcgtgccaac ctccctcagt ccttccaggt ggacacaagc aaggctggtg tggccccatt
4621 gcaggtcaaa gtgcaagggc ccaaaggcct ggtggagcca gtggacgtgg tagacaacgc
4681 tgatggcacc cagaccgtca attatgtgcc cagccgagaa gggccctaca gcatctcagt
4741 actgtatgga gatgaagagg taccccggag ccccttcaag gtcaaggtgc tgcctactca
4801 tgatgccagc aaggtgaagg ccagtggccc cgggctcaac accactggcg tgcctgccag
4861 cctgcccgtg gagttcacca tcgatgcaaa ggacgccggg gagggcctgc tggctgtcca
4921 gatcacggat cccgaaggca agccgaagaa gacacacatc caagacaacc atgacggcac
4981 gtatacagtg gcctacgtgc cagacgtgac aggtcgctac accatcctca tcaagtacgg
5041 tggtgacgag atccccttct ccccgtaccg cgtgcgtgcc gtgcccaccg gggacgccag
5101 caagtgcact gtcacagtgt caatcggagg tcacgggcta ggtgctggca tcggccccac
5161 cattcagatt ggggaggaga cggtgatcac tgtggacact aaggcggcag gcaaaggcaa
5221 agtgacgtgc accgtgtgca cgcctgatgg ctcagaggtg gatgtggacg tggtggagaa
5281 tgaggacggc actttcgaca tcttctacac ggccccccag ccgggcaaat acgtcatctg
5341 tgtgcgcttt ggtggcgagc acgtgcccaa cagccccttc caagtgacgg ctctggctgg
5401 ggaccagccc tcggtgcagc cccctctacg gtctcagcag ctggccccac agtacaccta
5461 cgcccagggc ggccagcaga cttgggcccc ggagaggccc ctggtgggtg tcaatgggct
5521 ggatgtgacc agcctgaggc cctttgacct tgtcatcccc ttcaccatca agaagggcga
5581 gatcacaggg gaggttcgga tgccctcagg caaggtggcg cagcccacca tcactgacaa
5641 caaagacggc accgtgaccg tgcggtatgc acccagcgag gctggcctgc acgagatgga
5701 catccgctat gacaacatgc acatcccagg aagccccttg cagttctatg tggattacgt
5761 caactgtggc catgtcactg cctatgggcc tggcctcacc catggagtag tgaacaagcc
5821 tgccaccttc accgtcaaca ccaaggatgc aggagagggg ggcctgtctc tggccattga
5881 gggcccgtcc aaagcagaaa tcagctgcac tgacaaccag gatgggacat gcagcgtgtc
5941 ctacctgcct gtgctgccgg gggactacag cattctagtc aagtacaatg aacagcacgt
6001 cccaggcagc cccttcactg ctcgggtcac aggtgacgac tccatgcgta tgtcccacct
6061 aaaggtcggc tctgctgccg acatccccat caacatctca gagacggatc tcagcctgct
6121 gacggccact gtggtcccgc cctcgggccg ggaggagccc tgtttgctga agcggctgcg
6181 taatggccac gtggggattt cattcgtgcc caaggagacg ggggagcacc tggtgcatgt
6241 gaagaaaaat ggccagcacg tggccagcag ccccatcccg gtggtgatca gccagtcgga
6301 aattggggat gccagtcgtg ttcgggtctc tggtcagggc cttcacgaag gccacacctt
6361 tgagcctgca gagtttatca ttgatacccg cgatgcaggc tatggtgggc tcagcctgtc
6421 cattgagggc cccagcaagg tggacatcaa cacagaggac ctggaggacg ggacgtgcag
6481 ggtcacctac tgccccacag agccaggcaa ctacatcatc aacatcaagt ttgccgacca
6541 gcacgtgcct ggcagcccct tctctgtgaa ggtgacaggc gagggccggg tgaaagagag
6601 catcacccgc aggcgtcggg ctccttcagt ggccaacgtt ggtagtcatt gtgacctcag
6661 cctgaaaatc cctgaaatta gcatccagga tatgacagcc caggtgacca gcccatcggg
6721 caagacccat gaggccgaga tcgtggaagg ggagaaccac acctactgca tccgctttgt
6781 tcccgctgag atgggcacac acacagtcag cgtcaagtac aagggccagc acgtgcctgg
6841 gagccccttc cagttcaccg tggggcccct aggggaaggg ggagcccaca aggtccgagc
6901 tgggggccct ggcctggaga gagctgaagc tggagtgcca gccgaattca gtatctggac
6961 ccgggaagct ggtgctggag gcctggccat tgctgtcgag ggccccagca aggctgagat
7021 ctcttttgag gaccgcaagg acggctcctg tggtgtggct tatgtggtcc aggagccagg
7081 tgactacgaa gtctcagtca agttcaacga ggaacacatt cccgacagcc ccttcgtggt
7141 gcctgtggct tctccgtctg gcgacgcccg ccgcctcact gtttctagcc ttcaggagtc
7201 agggctaaag gtcaaccagc cagcctcttt tgcagtcagc ctgaacgggg ccaagggggc
7261 gatcgatgcc aaggtgcaca gcccctcagg agccctggag gagtgctatg tcacagaaat
7321 tgaccaagat aagtatgctg tgcgcttcat ccctcgggag aatggcgttt acctgattga
7381 cgtcaagttc aacggtaccc acatccctgg aagccccttc aagatccgag ttggggagcc
7441 tgggcatgga ggggacccag gcttggtgtc tgcttacgga gcaggtctgg aaggcggtgt
7501 cacagggaac ccagctgagt tcgtcgtgaa cacgagcaat gcgggagctg gtgccctgtc
7561 ggtgaccatt gacggcccct ccaaggtgaa gatggattgc caggagtgcc ctgagggcta
7621 ccgcgtcacc tataccccca tggcacctgg cagctacctc atctccatca agtacggcgg
7681 cccctaccac attgggggca gccccttcaa ggccaaagtc acaggccccc gtctcgtcag
7741 caaccacagc ctccacgaga catcatcagt gtttgtagac tctctgacca aggccacctg
7801 tgccccccag catggggccc cgggtcctgg gcctgctgac gccagcaagg tggtggccaa
7861 gggcctgggg ctgagcaagg cctacgtagg ccagaagagc agcttcacag tagactgcag
7921 caaagcaggc aacaacatgc tgctggtggg ggttcatggc ccaaggaccc cctgcgagga
7981 gatcctggtg aagcacgtgg gcagccggct ctacagcgtg tcctacctgc tcaaggacaa
8041 gggggagtac acactggtgg tcaaatgggg gcacgagcac atcccaggca gcccctaccg
8101 cgttgtggtg ccctgagtct ggggcccgtg ccagccggca gcccccaagc ctgccccgct
8161 acccaagcag ccccgccctc ttcccctcaa ccccggccca ggccgccctg gccgcccgcc
8221 tgtcactgca gctgcccctg ccctgtgccg tgctgcgctc acctgcctcc ccagccagcc
8281 gctgacctct cggctttcac ttgggcagag ggagccattt ggtggcgctg cttgtcttct
8341 ttggttctgg gaggggtgag ggatgggg
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