GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG1 272 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene 5' flanking region and exon 1
ACCESSION X02189
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 272)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT EPD; 11113; Hs ADA.
From EMBL entry HSADAG1; dated 06-JUL-1989.
FEATURES Location/Qualifiers
misc_feature 1..226
/note="5' untranslated region"
repeat_region 24..39
/note="direct repeat 1"
misc_feature 28..34
/note="G/C-rich motif"
misc_feature 33..39
/note="G/C-rich motif"
misc_feature 53..103
/note="pot. stem loop structure"
misc_feature 53..59
/note="G/C-rich motif"
repeat_region 72..87
/note="direct repeat 1'"
misc_feature 76..82
/note="G/C-rich motif"
misc_feature 80..87
/note="G/C-rich motif"
misc_feature 113..137
/note="pot. stem loop structure"
repeat_region 126..135
/note="direct repeat 2"
precursor_RNA 132..>272
/note="put. primary transcript"
mRNA 132..259
/note="exon 1"
repeat_region 156..165
/note="direct repeat 2'"
CDS 227..259
/note="adenosine deaminase (aa 1-11)"
/codon_start=227
intron 260..>272
/note="intron I"
BASE COUNT 45 a 93 c 122 g 12 t
ORIGIN
1 tccaggaaat gcgcgatcca ggccggcggg cggggcgggg gctccggcga gagggcgggc
61 cccgggaacg gcggcgggcg gggcgggagg cggggcccgg cccgttaaga agagcgtggc
121 cggccgcggc caccgctggc cccagggaaa gccgagcggc caccgagccg gcagagaccc
181 accgagcggc ggcggaggga gcgacgccgg ggcgcacgag ggcaccatgg cccagacgcc
241 cgccttcgac aagcccaaag tgagcgcgcg cg
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG10 144 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 10
ACCESSION X02197
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 144)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG10; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..6
/note="intron IX"
mRNA 7..136
/note="exon 10"
CDS 7..136
/note="adenosine deaminase (aa 273-315) (7 is 3rd base in
codon)"
/codon_start=7
intron 137..>144
/note="intron X"
BASE COUNT 43 a 37 c 35 g 29 t
ORIGIN
1 ctgcaggctc aaaaatgacc aggctaacta ctcgctcaac acagatgacc cgctcatctt
61 caagtccacc ctggacactg attaccagat gaccaaacgg gacatgggct ttactgaaga
121 ggagtttaaa aggctggtga gtgg
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG11 155 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 11
ACCESSION X02198
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 155)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG11; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..19
/note="intron X"
mRNA 20..122
/note="exon 11"
CDS 20..122
/note="adenosine deaminase (aa 316-350) (122 is 1st base
in codon)"
/codon_start=20
intron 123..>155
/note="intron XI"
BASE COUNT 33 a 44 c 38 g 40 t
ORIGIN
1 gccattctgg cctttccaga acatcaatgc ggccaaatct agtttcctcc cagaagatga
61 aaagagggag cttctcgacc tgctctataa agcctatggg atgccacctt cagcctctgc
121 aggtaggttc ctgtctgggc ttctgggcag ttgcc
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG12 323 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 12 and 3' flanking region
ACCESSION X02199
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 323)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG12; dated 06-JUL-1989.
FEATURES Location/Qualifiers
mRNA 1..11
/note="exon 12"
CDS 1..11
/note="adenosine deaminase (aa 351-354) (1 is 2nd base in
codon)"
/codon_start=1
misc_feature 12..>323
/note="3' untranslated region"
misc_feature 297..302
/note="polyadenylation signal"
BASE COUNT 74 a 95 c 70 g 84 t
ORIGIN
1 ggcagaacct ctgaagacgc cactcctcca agccttcacc ctgtggagtc accccaactc
61 tgtggggctg agcaacattt ttacatttat tccttccaag aagaccatga tctcaatagt
121 cagttactga tgctcctgaa ccctatgtgt ccatttctgc acacacgtat acctcggcat
181 ggccgcgtca cttctctgat tatgtgccct ggccagggac cagcgccctt gcacatgggc
241 atggttgaat ctgaaaccct ccttctgtgg caacttgtac tgaaaatctg gtgctcaata
301 aagaagccca tggctggtgg cat
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG2 153 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 2
ACCESSION X02190
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 153)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG2; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..45
/note="intron I"
mRNA 46..107
/note="exon 2"
CDS 46..107
/note="adenosine deaminase (aa 12-32) (107 is 2nd base in
codon)"
/codon_start=46
intron 108..>153
/note="intron II"
BASE COUNT 30 a 51 c 29 g 43 t
ORIGIN
1 ttctctctct ccctttctct ctctcttccc cctgccccct tgcaggtaga actgcatgtc
61 cacctagacg gatccatcaa gcctgaaacc atcttatact atggcaggta agtccataca
121 gaagagccct ctctccctgg gatttgagtg ggg
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG3 180 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 3
ACCESSION X02191
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 180)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG3; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..105
/note="intron II"
mRNA 106..168
/note="exon 3"
CDS 106..168
/note="adenosine deaminase (aa 33-73) (106 is 3rd base in
codon) (168 is 2nd base in codon)"
/codon_start=106
intron 169..>180
/note="intron III"
BASE COUNT 34 a 58 c 47 g 41 t
ORIGIN
1 ggatcctgcc ccgggttggt ccaccactca ctgttttgtt tccaggagga gagggatcgc
61 cctcccagct aacacagcag aggggctgct gaacgtcatt ggcatggaca agccgctcac
121 ccttccagac ttcctggcca agtttgacta ctacatgcct gctatcgcgt gagttgcccc
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG4 185 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 4
ACCESSION X02192
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 185)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG4; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..20
/note="intron III"
mRNA 21..164
/note="exon 4"
CDS 21..164
/note="adenosin deaminase (aa 74-111) (21 is 3rd base in
codon) (164 is 2nd base in codon)"
/codon_start=21
intron 165..>185
/note="intron IV"
BASE COUNT 40 a 46 c 62 g 37 t
ORIGIN
1 cccctttctt cccttcccag gggctgccgg gaggctatca aaaggatcgc ctatgagttt
61 gtagagatga aggccaaaga gggcgtggtg tatgtggagg tgcggtacag tccgcacctg
121 ctggccaact ccaaagtgga gccaatcccc tggaaccagg ctgagtgagt gatgggcctg
181 gaagg
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG5 182 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 5
ACCESSION X02193
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 182)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG5; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..17
/note="intron IV"
mRNA 18..133
/note="exon 5"
CDS 18..133
/note="adenosin deaminase (aa 112-149) (18 is 3rd base in
codon) (133 is 1st base in codon)"
/codon_start=18
intron 133..>182
/note="intron V"
BASE COUNT 29 a 67 c 59 g 27 t
ORIGIN
1 ctcctctcct cacacagagg ggacctcacc ccagacgagg tggtggccct agtgggccag
61 ggcctgcagg agggggagcg agacttcggg gtcaaggccc ggtccatcct gtgctgcatg
121 cgccaccagc ccagtgagta ggatcaccgc cctgcccagg gcgcccgtct caccctggcc
181 ct
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG6 168 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 6
ACCESSION X02194
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 168)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG6; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..111
/note="intron V"
mRNA 112..140
/note="exon 6"
CDS 112..140
/note="adenosine deaminase (aa 150-192) (112 is 2nd base
in codon)"
/codon_start=112
intron 141..>168
/note="intron VI"
BASE COUNT 38 a 44 c 56 g 30 t
ORIGIN
1 tctcgcccac agactggtcc cccaaggtgg tggagctgtg taagaagtac cagcagcaga
61 ccgtggtggc cattgacctg gctggagatg agaccatccc aggaagcagc ctcttgcctg
121 gacatgtcca ggcctaccag gtgggtcctg tgagaaggaa tggagagg
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG9 95 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exon 9
ACCESSION X02196
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 95)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG9; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..20
/note="intron VIII"
mRNA 21..85
/note="exon 9"
CDS 21..85
/note="adenosine deaminase (aa 251-272) (85 is 2nd base in
codon)"
/codon_start=21
intron 86..>95
/note="intron IX"
BASE COUNT 17 a 34 c 24 g 20 t
ORIGIN
1 ccacacacct gctcttccag atctgcccct ggtccagcta cctcactggt gcctggaagc
61 cggacacgga gcatgcagtc attcggtgag ctctg
//GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMADAG78 371 bp ds-DNA PRI 26-MAY-1991
DEFINITION Human adenosine deaminase (ADA) gene exons 7 and 8
ACCESSION X02195
KEYWORDS adenosine deaminase; deaminase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 371)
AUTHORS Valerio,D., Duyvesteyn,M.G., Dekker,B.M., Weeda,G., Berkvens,T.M.,
van,d.V.L., vab,O.H. and van,d.E.A.J.
TITLE Adenosine deaminase:characterization and expression of a gene with
a remarkable promoter
JOURNAL EMBO J. 4, 437-443 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSADAG78; dated 06-JUL-1989.
FEATURES Location/Qualifiers
intron <1..27
/note="intron VI"
mRNA 28..99
/note="exon 7"
CDS 28..99
/note="adenosine deaminase (aa 193-216)"
/codon_start=28
intron 100..175
/note="intron VII"
mRNA 176..277
/note="exon 8"
CDS 176..277
/note="adenosine deaminase (aa 217-250)"
/codon_start=176
intron 278..>371
/note="intron VIII"
BASE COUNT 79 a 110 c 116 g 66 t
ORIGIN
1 cccgtgacct ggctctcccc cttccaggag gctgtgaaga gcggcattca ccgtactgtc
61 cacgccgggg aggtgggctc ggccgaagta gtaaaagagg tgagggcctg ggctggccat
121 ggggtccctc ctcactgcct cctcccatac ttggctctat tctgcttctc tacaggctgt
181 ggacatactc aagacagagc ggctgggaca cggctaccac accctggaag accaggccct
241 ttataacagg ctgcggcagg aaaacatgca cttcgaggta agcgggccag ggagtgggga
301 ggaaccatcc ccggctgtcc caacttcctg tatagagagg cagaaagcag ggcgggtccc
361 aggaactcga g
//