GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMAGTMR 1600 bp ss-mRNA PRI 26-MAY-1991
DEFINITION Human mRNA for peroxisomal L-alanine:glyoxylate aminotransferase.
ACCESSION X53414
KEYWORDS L-alanine; L-alanine:glyoxylate aminotransferase; aminotransferase;
glyoxylate.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1600)
AUTHORS Takada,Y.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Takada,Y., Kaneko,N., Esumi,H., Purdue,P.E. and Danpure,C.J.
TITLE Human peroxisomal L-alanine: glyoxylate aminotransferase:
Evolutionary loss of a mitochondrial targeting signal by point
mutation
JOURNAL Biochem. J. 268, 517-520 (1990)
STANDARD full staff_review
COMMENT *source: developmental stage=adult; tissue=liver; *source: cell
type=hepatoma; cell line=HepG2 hepatocarcinoma; *source: clone=
H1-2; library=lambda gt11;
From EMBL entry HSAGTMR; dated 16-JAN-1991.
FEATURES Location/Qualifiers
mRNA <123..1600
/gene="agt1"
mat_peptide 123..1298
/product="L-alanine:glyoxylate aminotransferase"
/gene="agt1"
CDS 123..1301
/EC_number="2.6.1.44"
/product="L- alanine:glyoxylate aminotransferase"
/gene="agt1"
/codon_start=123
misc_binding 209..209
/bound_moiety="putative cofactor"
polyA_signal 1573..1578
BASE COUNT 319 a 540 c 465 g 276 t
ORIGIN
1 ccggaagccc atccaccaat cctcacctct cacctctgtg tccgccctgc tgggaaatat
61 tccaggcttt ggccaaggcc agtgcagccc caggttcccg agcggcaggt tgggtgcgga
121 ccatggcctc tcacaagctg ctggtgaccc cccccaaggc cctgctcaag cccctctcca
181 tccccaacca gctcctgctg gggcctggtc cttccaacct gcctcctcgc atcatggcag
241 ccggggggct gcagatgatc gggtccatga gcaaggatat gtaccagatc atggacgaga
301 tcaaggaagg catccagtac gtgttccaga ccaggaaccc actcacactg gtcatctctg
361 gctcgggaca ctgtgccctg gaggccgccc tggtcaatgt gctggagcct ggggactcct
421 tcctggttgg ggccaatggc atttgggggc agcgagccgt ggacatcggg gagcgcatag
481 gagcccgagt gcacccgatg accaaggacc ctggaggcca ctacacactg caggaggtgg
541 aggagggcct ggcccagcac aagccagtgc tgctgttctt aacccacggg gagtcgtcca
601 ccggcgtgct gcagcccctt gatggcttcg gggaactctg ccacaggtac aagtgcctgc
661 tcctggtgga ttcggtggca tccctgggcg ggacccccct ttacatggac cggcaaggca
721 tcgacatcct gtactcgggc tcccagaagg ccctgaacgc ccctccaggg acctcgctca
781 tctccttcag tgacaaggcc aaaaagaaga tgtactcccg caagacgaag cccttctcct
841 tctacctgga catcaagtgg ctggccaact tctggggctg tgacgaccag cccaggatgt
901 accatcacac aatccccgtc atcagcctgt acagcctgag agagagcctg gccctcattg
961 cggaacaggg cctggagaac agctggcgcc agcaccgcga ggccgcggcg tatctgcatg
1021 ggcgcctgca ggcactgggg ctgcagctct tcgtgaagga cccggcgctc cggcttccca
1081 cagtcaccac tgtggctgta cccgctggct atgactggag agacatcgtc agctacgtca
1141 tagaccactt cgacattgag atcatgggtg gccttgggcc ctccacgggg aaggtgctgc
1201 ggatcggcct gctgggctgc aatgccaccc gcgagaatgt ggaccgcgtg acggaggccc
1261 tgagggcggc cctgcagcac tgccccaaga agaagctgtg acctgcccac tggcacacag
1321 ctggcactgg cacacacctg tcccatgccc accctgaggg atcaggagca aacagaccct
1381 gcaaggtcct ccaggcctgg ggacaggaaa gccactgacc cagcccggga ggcagaacca
1441 ggcagcctcc ctggccccag gcagcccttt tccctccagt ggcacctcct ggaaacagtc
1501 cacttgggcg caaaacccag tgccttccaa atgagctgca gtccccaggc catgagcctc
1561 ccgggaatgt ttaataaagg gcctggccac ctctcctcac
//