GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMALKPHO 2480 bp ss-mRNA PRI 26-MAY-1991 DEFINITION Human mRNA for placental-like alkaline phosphatase (EC 3.1.3.1) ACCESSION X53279 KEYWORDS alkaline phosphatase. SOURCE Homo sapiens RNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (sites) AUTHORS Gum,J.R. JOURNAL Unpublished (1990) STANDARD full staff_review REFERENCE 2 (bases 1 to 2480) AUTHORS Gum,J.R., Hicks,J.W., Sack,T.L. and Kim,Y.S. TITLE Molecular Cloning of Complentary DNAs Encoding Alkaline Phosphatase in Human Colon Cancer Cells JOURNAL Cancer Res. 50, 1085-1091 (1990) STANDARD full automatic COMMENT *source: tissue type=colon; cell type=carcinogenic; *source: cell line=LS174T. **map: chromosome=2q34-37. Data kindly reviewed (13-DEC-1990) by Gum J.R. From EMBL entry HSALKPHO; dated 14-DEC-1990. FEATURES Location/Qualifiers CDS 4..1599 /note="protein precursor (AA -19 to 513)" /codon_start=4 CDS 4..60 /note="signal peptide (AA -19 to -1)" /codon_start=4 CDS 61..1599 /note="mature protein (AA 1 - 513)" /codon_start=61 polyA_site 2438..2438 /note="polyA site" BASE COUNT 523 a 805 c 720 g 432 t ORIGIN 1 gacatgcagg ggccctgggt gctgctcctg ctgggcctga ggctacagct ctccctgggc 61 atcatcccag ttgaggagga gaacccggac ttctggaacc gccaggcagc cgaggccctg 121 ggtgccgcca agaagctgca gcctgcacag acagccgcca agaacctcat catcttcctg 181 ggtgacggga tgggggtgtc tacggtgaca gctgccagga tcctaaaagg gcagaagaag 241 gacaaactgg ggcctgagac cttcctggcc atggaccgct tcccgtacgt ggctctgtcc 301 aagacataca gtgtagacaa gcatgtgcca gacagtggag ccacagccac ggcctacctg 361 tgcggggtca agggcaactt ccagaccatt ggcttgagtg cagccgcccg ctttaaccag 421 tgcaacacga cacgcggcaa cgaggtcatc tccgtgatga atcgggccaa gaaagcagga 481 aagtcagtgg gagtggtaac caccacacgg gtgcagcatg cctcgccagc cggcgcctac 541 gcccacacgg tgaaccgcaa ctggtactcg gatgccgacg tgcctgcctc ggcccgccag 601 gaggggtgcc aggacatcgc cacgcagctc atctccaaca tggacattga tgtgatccta 661 ggtggaggcc gaaagtacat gtttcccatg gggaccccag accctgagta cccagatgac 721 tacagccaag gtgggaccag gctggacggg aagaatctgg tgcaggaatg gctggcgaag 781 caccagggtg cccggtacgt gtggaaccgc actgagctca tgcaggcttc cctggacccg 841 tctgtgaccc atctcatggg tctctttgag cctggagaca tgaaatacga gatccaccga 901 gactccacac tggacccctc cctgatggag atgacagagg ctgccctgcg cctgctgagc 961 aggaaccccc gcggcttctt cctcttcgtg gagggtggtc gcatcgacca tggtcatcat 1021 gaaagcaggg cttaccgggc actgactgag acgatcatgt tcgacgacgc cattgagagg 1081 gcgggccagc tcaccagcga ggaggacacg ctgagcctcg tcactgccga ccactcccac 1141 gtcttctcct tcggaggcta ccccctgcga gggagctcca tcttcgggct ggcccctggc 1201 aaggcccggg acaggaaggc ctacacggtc ctcctatacg gaaacggtcc aggctatgtg 1261 ctcaaggacg gcgcccggcc ggatgttacc gagagcgaga gcgggagccc cgagtatcgg 1321 cagcagtcag cagtgcccct ggacggagag acccacgcag gcgaggacgt ggcggtgttc 1381 gcgcgcggcc cgcaggcgca cctggttcac ggcgtgcagg agcagacctt catagcgcac 1441 gtcatggcct tcgccgcctg cctggagccc tacaccgcct gcgacctggc gcccagcgcc 1501 ggcaccaccg acgccgcgca cccggggccg tccgtggtcc ccgcgttgct tcctctgctg 1561 gcagggacct tgctgctgct ggggacggcc actactccct gagtgtcccg tccctggggc 1621 tcctgcttcc ccatcccgga gttcccctgc tccccacctc cagtcgtcct gccggacctc 1681 cacctggagc tgtcaccccc ggagtcgcca cacagacgtc ctgccatgga accttcccct 1741 cccggtgcac cctggggacc gagcccttga caccacgccc tttgctttat cttgctcttg 1801 aaattttggc cccaactcca gggactgggg atttgtgcct ggcagctgcc tgcatttcag 1861 gaaaagagga ggctcagacc atccagcccc cgcccatatg ctgaggtgga tcaggcaggc 1921 tctctccccg gggacatgag gcacccatac ctaggacccc ctgcgccttt tttagcttca 1981 gtcatggcag cacctgaggg acacaaggac ttgggtgcat caggacgcct tggagaagcg 2041 tggcttcctg ccaccctgca acccaccctc ccagccaagg aggctgctgt ggtggggatc 2101 cccagggggg ctttgacaca gtcctctgct gtccctccac tgggctaatt ctacacccct 2161 gtgcccctcc taggggccca tgagtcagag aggcttgccc caagtcacag ccactcagat 2221 gttcgacgcc ccctaaggtc cattccagca cccacctgag ttccgaggag cacctgggaa 2281 gctctgggtg caggatagca gtccagagtc catggccccg cctaggccat ctgggtgctg 2341 ggcatggatt tctcagcaag gaagactcat taccttccct ccctgggcct ccattcttct 2401 gggaaacaca aagcaataat aaaaggaagt gttagacaaa aaaaaaaaaa aaaaaaaaaa 2461 aaaaaaaaaa aaaaaaaaaa //