GenBank-Updates@genbank.bio.net (05/26/91)
LOCUS HUMHLA1 4123 bp ds-DNA PRI 26-MAY-1991
DEFINITION Complete human gene for class I transplantation antigen.
ACCESSION V00526
KEYWORDS germline; transplantation antigen.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4123)
AUTHORS Malissen,M., Malissen,B. and Jordan,B.R.
TITLE Exon/intron organization and complete nucleotide sequence of an HLA
gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 893-897 (1982)
STANDARD full automatic
COMMENT SWISS-PROT; P01893; HA1V$HUMAN.
It is not clear whether the authors intended the C in position 2701
really to be there or not. It interrupts the otherwise regular
spacing of the sequence printout.
From EMBL entry HSHLA1; dated 03-JAN-1991.
FEATURES Location/Qualifiers
CDS join(245..308,434..703,946..1221,1792..2067,2171..2287,
2729..2761,2904..2944)
/codon_start=245
intron 309..433
/note="first intron"
intron 704..945
/note="second intron"
intron 1222..1791
/note="third intron"
intron 2068..2170
/note="fourth intron"
intron 2288..2728
/note="fifth intron"
unsure 2701..2701
/note="C may be missing (Not legible in [1])"
intron 2762..2903
/note="sixth intron"
BASE COUNT 839 a 1125 c 1173 g 984 t 2 others
ORIGIN
1 cccgaaggcg gtgtatggat tggggatgcc ccgccttggg gattcgccac ctccgcagtt
61 tctcttcttc tcacaacctg cgacgggtcc ttcttcctcg atactcacga agcggacaca
121 gttctcattc ccactaggtg tcgggtttct agagaagcca atcggtgccg ccgcggtccc
181 ggttctaaag tccccacgca cccaccggga ctcagattct ccccagacgc cgaggatggt
241 gctcatggcg ccccgaaccc tcctcctgct gctctcaggg gccctggccc tgacccagac
301 ctgggcgcgt gagtgcaggg tctgcaggga aatggtcggg aggagngagg ggcccgcccg
361 gcggggtgcg caggacccag ggagccgcgc agggaggagg gtcgggcggg tctcagctcc
421 tcctcgctcc caggttccca ctccatgagg tatttctaca ccaccatgtc ccggcccggc
481 gccggggagc cccgcttcat ctccgtcggc tacgtggacg atacgcagtt cgtgcggttc
541 gacagcgacg acgcgagtcc gagagaggag ccgcgggcgc cgtggatgga gcgggagggg
601 ccaaagtatt gggaccggaa cacacagatc tgcaaggccc aggcacagac tgaacgagag
661 aacctgcgga tcgcgctccg ctactacaac cagagcgagg gcggtgagtt gaccccggcc
721 cggggcgcag gtcacgaccc ctccccatcc cccacggagg gccgggtcgc ctcgagtctc
781 tgggtccgag atccaccccg aaaccgcggg atcccgagac ccttgacctg ggagaggccc
841 aggcgccttt acccggtttc attttcagtt taggccaaaa tccccgcggg ttggtcgggg
901 cggggctggg ctcgggggac cgggctgacc gcgggggcgg gccaggttct cacaccatgc
961 aggtgatgta tggctgcgac gtggggcccg acgggccttt cctccgcggg tatgaacagc
1021 acgcctacga cggcaaggat tacatcgccc tgaacgagga cctgcgctcc tggaccgcgg
1081 cggacatggc agctcagatc accaagcgca agtgggaggc ggcccgtcgg gcggagcagc
1141 ggagagtcta cttggagggc gagttcgtgg agtggctccg cagatacttg gagaacggga
1201 aggagacgct gcagcgcgcg ggtaccaggg ccacagggcg cctccctgat cgcctgtaga
1261 tctccggggc tggcctccca caagaaaggg agacaaatgg gaccaacact ataatatcgc
1321 cctccctctg gtcttgaggg agaagaatcc tcttgggttt ccagagagtg actctgaggg
1381 tccgccctgc tctctgacac aattaaggga tgaaatctgt gaggaaatga agggaagaca
1441 atccctggaa tactgatgag tggttccctt tgacactggc agcagccttg ggccccgtga
1501 cttttcctct caggccttgt tctctgcttc acactcaatg tgcgtggggg tctgagtccc
1561 tcagcctcca ctcaggtcag gaccagaagt cgctgttccc tcttcaggga ctagaatttt
1621 ccacggaata ggagattatt ctaggtgcct ctgtctaggc tgttgtctgg gttctgtgct
1681 cccttcccca ccctaggcat cctgtcaatt ctcaagatgg ccacatgcgt gctggtggag
1741 tgtcccatga cagatgcaaa atgcctgaat tttctgactc tttcccgtca gaccccccca
1801 agacacatat gacccaccac cccatctctg accatgaggc caccctgagg tgctgggccc
1861 tgggcttcta ccctgcggag atcacactga cctggcagcg ggatggggag gaccagaccc
1921 aggacacgga gctcgtggag accaggcctg caggggatgg aaccttccag aagtgggcgg
1981 ctgtggtggt gccttctgga gaggagcaga gatacacctg ccatgtgcag catgagggtc
2041 tgcccgagcc cctcaccctg agatggggta aggagggaga tgggggtgtc atgtctctta
2101 gggaaagccg gagacctctc tggagagctt agcagggtca gggttccctc accttccccc
2161 cttttcccag agccatcttc ccagcccacc gtccccatcg tgggcatcgt tgctggcttg
2221 gttctacttg tagctgtggt cactggagct gtggtcgctg ctgtaatgtg gaggaagaag
2281 agctcaggta aggaaggggt gaggagtgtg gtctgagaat ttcttgtctc actgagagtt
2341 ccaagcccca agtagaagtg ccctgcctag ttactgggaa gcaccatcca cactcatggg
2401 cctacccagc ctgggccctg tgtgccagca cttactcttt tgtaaagcac ctgttacaat
2461 gagggacaga tttattacct tgatgactgt ggtgatggga cctgatccca gcagtcacaa
2521 gtcacagggg aaggtccccg aggacagacc tcagaagggc ggttggtcna ggacccacat
2581 ctgctttctt catgtttcct gatcccgccc tgggtctgca gttgcacatt tctggaaact
2641 tctctggggt ccgagacttg gaggttcctc taggacctta tggccctggc ttctttctgg
2701 catctcacag gacattttct tcccacagat agaaaaggag ggagctactc tcaggctgca
2761 agtaagtatg aaggaggctg atccctgaaa tcctttggat attgtgtttg ggagcccatg
2821 ggggagctca cccaccccac aattcttcct ctagccacat ctactgtggg atctgaccag
2881 gtcctgtttt tattctactc caggcagcaa cagtgcccag ggctctgatg tgtctctcac
2941 ggcttgaaac ctgagacctt ggggggcctg atgtgtgggg gatgttgggg gggaacagtg
3001 gacacagctg tgctatgggg ttctttgaat ttgatgtttt gagcatgcga tgggctgcca
3061 aagtgtcatc cattactggg acagatatga atttgttcat gaatattttt tctatagtgt
3121 gagacagctg ccttgtgtgg gactgagagg caagagttgt tcctgccttc cctttgtgac
3181 ttgaagaacc ctgactttct ttctacaaag gcacctgaat gtgtctgtgt tcctgtaggc
3241 ataatgtgtg gaggagggga gaccaaccca ccctcatgtc caccatgacc ctcttcccca
3301 cgctgactgt gttccctccc caatcatctt tcctgttcca gagaggaggg gctgagatgt
3361 ctccatcttt ttctcaactt tatgtgcact gagctgtaat tcttacttcc ctcttaaaat
3421 tgaatcttga gtaaacattt actttttcaa attcttgcca tgagagggtt gatgacttaa
3481 ttaaaggaga agattcctaa aatttgagag acaaaataaa tggaacacat gagaaccttc
3541 cagagtccat gtgtttcttg tgctgatttg ttgcagggga ggagaatagg tggggctgtg
3601 cctagtgggt gctcaggccc agtatggact ttatgtggtc actgctcagc tgggtcatct
3661 ttgctccttc attctccttg gcccttcagt agaaccttgt cctaccacca cctgtgatca
3721 cagggacttg gatgtcacct acagtggtcc ctgcatacaa atctcattgt agtatcaaga
3781 gactaatttt cagacctgtc cagctcttgc cctcctccta gggctctttc ctggattgta
3841 tttttcatct tgcctccaat ctttttaaag gaagcagatt ctaaaatttg cagagaggag
3901 gggcccatag tttctcatca tagtgaactt tctgttggag ctcctcttct gctctcttac
3961 tcttcttcct tccctgagtt gtagtaatcc tagtgctggc tccagtccaa actcatggat
4021 ttacaaagca gagtctaatt tagattcata cgtggttgga aaattggacc cataagccta
4081 gggttatctt tcctgaagag aaaaatatgg ttgtgtgctg cag
//