GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS STRPENA 2291 bp ds-DNA BCT 27-MAY-1991
DEFINITION Streptococcus pneumoniae penA gene encoding penicillin binding
protein 2B.
ACCESSION X16022 X13137
KEYWORDS cytoplasmic membrane protein; penA gene;
penicillin binding protein; serine peptidase; transpeptidase.
SOURCE Streptococcus pneumoniae DNA.
ORGANISM Streptococcus pneumoniae
Prokaryota; Bacteria; Firmicutes; Gram-positive cocci;
Streptococcaceae.
REFERENCE 1 (bases 1 to 2291; 812 to 2291)
AUTHORS Dowson,C.G.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 812 to 2291)
AUTHORS Dowson,C.G., Hutchinson,A. and Spratt,B.G.
TITLE Extensive re-modelling of the transpeptidase domain of
pencillin-binding 2b of a pencillin-resistant South African isolate
of Streptococcus pneumoniae
JOURNAL Mol. Microbiol. 3, 95-102 (1989)
STANDARD full automatic
REFERENCE 3 (bases 1 to 2291)
AUTHORS Dowson,C.G., Hutchison,A. and Spratt,B.G.
TITLE Nucleotide sequence of the penicillin-binding protein 2B gene of
Streptococcus pneumoniae strain R6
JOURNAL Nucleic Acids Res. 17, 7518-7518 (1989)
STANDARD full automatic
COMMENT SWISS-PROT; P10524; PBP2$STRPN.
*source: strain=R6;
Data kindly reviewed (20-Mar-1989) by Spratt B.G. [3], [4]
From EMBL entry SPPENA; dated 23-NOV-1989.
FEATURES Location/Qualifiers
CDS 233..2269
/note="penicillin binding protein 2B (AA 1-679)"
/codon_start=233
BASE COUNT 709 a 437 c 494 g 651 t
ORIGIN
1 gatatctggt ttgtccatag ggaaagctcc tttacatgag tcatactgga agactagatc
61 agggaatagt cacacttcat tataacacat aatataagga tagataaata aaaacgcatc
121 tctgttttaa aaacgaaaaa atcgaaaaag cttctctctt ttccataatt ttctactcaa
181 attgtggtac aattaagagt aagattttaa gttagaaatg agactgattt gtatgagaaa
241 atttaacagc cattcgattc cgattcggct taatttattg ttttcaatcg tcattttact
301 ctttatgacc attattggtc gtttgttgta tatgcaggtt ttcaacaagg atttttacga
361 aaaaaagcta gcctcagcta gtcagaccaa gattacaagc agttcagccc gtggggaaat
421 ttatgatgct agtggaaaac ctttggtaga aaatacgtta aagcaggttg tttcctttac
481 gcgtagcaat aaaatgacgg ctacagactt aaaagaaaca gctaaaaagt tactgactta
541 tgtgagcatc agttctccaa atttgacaga acgagctggg gattactatt tggctgatcc
601 tgaaatctat aaaaaaatag tggaagctct cccaagcgag aaacgcttgg attcagatgg
661 caatcgtcta tccgaatcag aactgtataa caatgcggtc gatagtgtac aaacgagtca
721 actaaactat acagaggatg aaaagaaaga aatctatctt tttagtcagt taaatgctgt
781 tggaaacttt gcgacaggga ccattgctac agatcctcta aatgattctc aggtggctgt
841 tattgcctct atttcaaagg agatgcctgg cattagtatt tctacttctt gggatagaaa
901 ggttttggaa acttcccttt cttctatagt tgggagtgta tccagtgaaa aagctggtct
961 cccagcggaa gaagcagaag cctatcttaa aaaaggctat tctctaaatg accgtgtagg
1021 aacctcctat ttggaaaagc aatatgaaga gaccttacaa ggaaaacgct cggtaaaaga
1081 aatccatctg gataaatatg gcaatatgga aagcgtggat acaattgagg aaggtagtaa
1141 gggaaacaat atcaaactga ccattgattt ggctttccaa gatagcgtgg atgctttact
1201 gaaaagttat ttcaattctg agctagaaaa tggtggagcc aagtattctg aaggtgtcta
1261 tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct atgtcaggga ttaaacatga
1321 cttgaaaacg ggagagttga cgcctgattc cttgggaacg gtaaccaatg tctttgttcc
1381 aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg gaaaatggag tcttgtcagg
1441 aaaccagacc ttgacagacc agtccattgt cttccaaggt tcagctccca tcaattcttg
1501 gtatactcag gcttacggtt cattccctat cacagcggtc caagctctgg agtattcatc
1561 aaatacctat atggtccaaa cagccttagg tcttatgggg caaacctatc aacccaatat
1621 gtttgtcggc accagcaatc tagagtctgc tatggagaaa ctgcgttcaa cctttggcga
1681 atatggcttg ggtactgcga caggaattga cctaccagat gaatctactg gatttgttcc
1741 caaagagtat agctttgcta attacattac taatgccttt gggcagtttg ataactatac
1801 gccgatgcag ttggctcagt atgtagcaac tattgcaaat aatggtgttc gtgtggctcc
1861 tcgtattgtt gaaggcattt atggtaataa tgataaggga ggactgggtg acttgattca
1921 gcaactgcaa ccgacagaga tgaataaggt caatatatcc gactccgata tgagcatctt
1981 gcaccaaggt ttttatcagg ttgcccatgg tactagtgga ttgacaactg gacgtgcctt
2041 ttcaaatggt gccttggtat ccattagcgg aaaaacaggt acagccgaaa gctatgtggc
2101 agatggtcag caagcaacca ataccaatgc ggtggcctat gccccatctg ataatcccca
2161 aatcgctgtc gcagtggtct ttcctcataa taccaatcta acaaatggtg taggaccttc
2221 cattgcgcgt gacattatca atctctatca aaaataccat ccaatgaact agaaaggaaa
2281 ttatgcttta t
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