GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCRAF18 88 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human activated c-raf-1 gene intron VII (fragment).
ACCESSION X05937 Y00344
KEYWORDS oncogene; raf cellular oncogene.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 88)
AUTHORS Tahira,T.
JOURNAL Unpublished (1987)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Tahira,T., Ochiai,M., Hayashi,K., Nagao,M. and Sugimura,T.
TITLE Activation of a human c-raf-1 by replacing the N-terminal region
with different sequences
JOURNAL Nucleic Acids Res. 15, 4809-4820 (1987)
STANDARD full staff_review
COMMENT In intron VII of the activated gene the inverted sequence
surrounding the recombination point was found to have the opposite
orientation in comparison to the intron of the normal gene (see
x05936). *source: cell line=NIH 3T3
From EMBL entry HSCRAF18; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..79
/note="Intron VII"
repeat_unit 1..9
/note="imp. inverted repeat A"
misc_feature 17..52
/note="inverted sequence with opposite orientation."
repeat_unit 48..52
/note="imp. inverted repeat A'"
mRNA 80..>88
/note="Exon 8"
BASE COUNT 24 a 18 c 20 g 26 t
ORIGIN
1 ccttctctca aagcaccaaa agattttctc tgggggaggg aaaaaagagg agttgaccag
61 ctttcctttt ctgtttcagg atgcaatt
//