GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45A 1011 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450(SCC) exon 1
ACCESSION X05367
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1011)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE-2-33-2; *source: library=(lambda)
gtWES.(lambda)B and Charon28; see X05368-74 for remaining exons
From EMBL entry HSCYP45A; dated 02-APR-1988.
FEATURES Location/Qualifiers
promoter 548..552
/note="put. CATT sequence"
promoter 586..591
/note="put. TATA sequence"
CDS 677..945
/note="desmolase (exon 1) (AA 1-90) (945 is 2nd base in
codon)"
/codon_start=677
intron 946..>1011
/note="intron I"
BASE COUNT 245 a 258 c 293 g 215 t
ORIGIN
1 ctgtactgaa ttacagcccc aaatctgggt caactgggga gagacgacga ggattagggt
61 tccaaggtga aactgtgcca ttgcgctcca gcctgggcaa caagaatgaa actctcttaa
121 aataaaataa aataaaataa aataaaatag cctaaggatg catttctcag aacttatccc
181 tgttgttcaa tgatgtgtgt ctatacagtg gggccataac taagacgtat gttgcccaag
241 ctggcaagat agctctgacc ttctcttggg cccctcattt cccccaaaca caggttgtct
301 gcagtcttga ccaatggctg ccagggcatg gactccgctg caggggccag tgggaggccc
361 cagctcaggc aaaagcacag gcagatattt caggagtctg ctagggctgg cactgagggc
421 agagacagag gggtctccct gtcctttgga gaacctcacg ctgcagaaat tccagactga
481 accttgatac cgagtagggg aggagctgtc tgcgggtttg agcctgcagc aggaggaagg
541 acgtgaacat tttatcagct tctggtatgg ccttgagctg gtagttataa tcttggccct
601 ggtggcccag ggctacagtc atcctagcag tccccgctga agtggagcag gtacagtcac
661 agctgtgggg acagcaatgc tggccaaggg tcttccccca cgctcagtcc tggtcaaagg
721 ctgccagacc tttctgagtg cccccaggga ggggctgggg cgtctcaggg tgcccactgg
781 cgagggagct ggcatctcca cccgcagtcc tcgccccttc aatgagatcc cctctcctgg
841 tgacaatggc tggctaaacc tgtaccattt ctggagggag acgggcacac acaaagtcca
901 ccttcaccat gtccagaatt tccagaagta tggcccgatt tacaggtaag cctggcagag
961 ggtgggagcc gaaggacagg gaggaggagg ggactgggta gccctgctgt a
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45B 310 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450(SCC) exon 2
ACCESSION X05368
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 310)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE1-1; library=Charon4A genomic; see
X05367 and x05369-74 for remaining exons
From EMBL entry HSCYP45B; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..36
/note="intron I"
mRNA 37..192
/note="exon 2"
CDS 37..192
/note="desmolase (AA 91-142) (37 is 3rd base in codon)
(192 is 2nd base in codon)"
/codon_start=37
intron 193..>310
/note="intron II"
BASE COUNT 56 a 95 c 97 g 62 t
ORIGIN
1 gatccttcca tcagcccctc tcccccaccc ctccagggag aagctcggca acgtggagtc
61 ggtttatgtc atcgaccctg aagatgtggc ccttctcttt aagtccgagg gccccaaccc
121 agaacgattc ctcatcccgc cctgggtcgc ctatcaccag tattaccaga gacccatagg
181 agtcctgttg aagtgagtcc tgggccatct cccagggact ggagggaggt ggtggggagc
241 tgtggagagg gcagaggctg ggggtgaggg gctgaggcca ggcttgccct gtgcctccta
301 gcagggcctc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45D 411 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450(SCC) exon 3
ACCESSION X05369
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 411)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE1-1 and (lambda)hSCCB51-1; *source:
library=Charon4A and (lambda)gtWES.(lambda)B and Charon28;
From EMBL entry HSCYP45D; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..111
/note="intron II"
mRNA 112..311
/note="exon 3"
CDS 112..311
/note="desmolase (AA 143-208) (112 is 3rd base in codon)
(311 is 1st base in codon)"
/codon_start=112
intron 312..>411
/note="intron III"
BASE COUNT 77 a 102 c 135 g 97 t
ORIGIN
1 ggatgctgtg agctgtgact cagcttcctg ggaaaactga gtcagccccc tctgtgttca
61 ccaggcctgg ggtctgtgac catgagggct tgtgggccca tgttttctca ggaagtcggc
121 agcctggaag aaagaccggg tggccctgaa ccaggaggtg atggctccag aggccaccaa
181 gaactttttg cccctgttgg atgcagtgtc tcgggacttc gtcagtgtcc tgcacaggcg
241 catcaagaag gcgggctccg gaaattactc gggggacatc agtgatgacc tgttccgctt
301 tgcctttgag tgtaaggggg cttgcacctg gctggcagtg ggcatggggg tgggaggact
361 cagtgttcac tctcttacct tgaggttcag tacagaccct gcagaggcat t
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45E 356 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450(SCC) exon 4
ACCESSION X05370
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 356)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE1-1 and (lambda)hSCCB51-1; *source:
library=Charon28 and (lambda)gtWES.(lambda)B and Charon4A; see
x05367-69 and x05371-74 for remaining exons
From EMBL entry HSCYP45E; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..64
/note="intron III"
mRNA 65..268
/note="exon 4"
CDS 65..268
/note="desmolase (AA 209-276) (65 is 2nd base in codon)
(268 is 1st base in codon)"
/codon_start=65
intron 269..>356
/note="intron IV"
BASE COUNT 65 a 112 c 96 g 83 t
ORIGIN
1 gggagttgtg gctctcagat ggccccgtca gaaatggctc ctcagcctct tcctctccct
61 gcagccatca ctaacgtcat ttttggggag cgccagggga tgctggagga agtagtgaac
121 cccgaggccc agcgattcat tgatgccatc taccagatgt tccacaccag cgtccccatg
181 ctcaaccttc ccccagacct gttccgtctg ttcaggacca agacctggaa ggaccatgtg
241 gctgcatggg acgtgatttt gagtaaaggt gagggcttct ctggctgtgc tctcctcctc
301 ggagccccag gcctcagccg gctcctttgt cccacgctat gtcaatgggc gctgac
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45F 289 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450 (SCC) exon 5
ACCESSION X05371
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 289)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE1-1 and (lambda)hSCCB51-1; *source:
library=Charon28 and (lambda)gtWES.(lambda)B and Charon4A; see
x05367-70 and x05372-74 for remaining exons
From EMBL entry HSCYP45F; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..60
/note="intron V"
mRNA 61..221
/note="exon 5"
CDS 61..221
/note="desmolase (AA 277-330) (61 is 2nd base in codon)"
/codon_start=61
intron 222..>289
/note="intron VI"
BASE COUNT 61 a 97 c 71 g 60 t
ORIGIN
1 ccctccttcc cacccgcctg cagggaacct cactcttttt tctttcctcc ttccccacag
61 ctgacatata cacccagaac ttctactggg aattgagaca gaaaggaagt gttcaccacg
121 attaccgtgg catcctctac agactcctgg gagacagcaa gatgtccttc gaggacatca
181 aggccaacgt cacagagatg ctggcaggag gggtggacac ggtgaggtgg ctgtaggggc
241 ggcaccttgt tgccccctgt gcccacgtgc cccttcccca ccaggcccc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45G 250 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450(SCC) exon 6
ACCESSION X05372
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 250)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCB51-1 and (lambda)hSCCE3-1; *source:
library=Charon28 and (lambda)gtWES.(lambda)B and Charon4A; see
X05367-71 and x05373-74 for remaining exons
From EMBL entry HSCYP45G; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..19
/note="intron VI"
mRNA 20..186
/note="exon 6"
CDS 20..186
/note="desmolase (AA 331-386) (186 is 2nd base in codon)"
/codon_start=20
intron 187..>250
/note="intron VII"
BASE COUNT 60 a 88 c 67 g 35 t
ORIGIN
1 ataccctact ccccaccaga cgtccatgac cctgcagtgg cacttgtatg agatggcacg
61 caacctgaag gtgcaggata tgctgcgggc agaggtcttg gctgcgcggc accaggccca
121 gggagacatg gccacgatgc tacagctggt ccccctcctc aaagccagca tcaaggagac
181 actaaggcaa gcccacaacc acccatgccg cccccaactc caatccctgg gcagggccag
241 ggaagtgccc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45H 527 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450 (SCC) exon 7
ACCESSION X05373
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 527)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE3-1; see x05367-72 and x05374 for
remaining exons
From EMBL entry HSCYP45H; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..31
/note="intron VI"
mRNA 32..110
/note="exon 7"
CDS 32..110
/note="desmolase (AA387-412) (32 is 2nd base in codon)"
/codon_start=32
intron 111..245
/note="intron VII"
mRNA 246..443
/note="exon 8"
CDS 246..443
/note="desmolase (AA 413-478)"
/codon_start=246
intron 444..>527
/note="intron VIII"
BASE COUNT 106 a 152 c 149 g 120 t
ORIGIN
1 ccatcagctt ctgaggtccc tcctcccgca gacttcaccc catctccgtg accctgcaga
61 gatatcttgt aaatgacttg gttcttcgag attacatgat tcctgccaag gtaggtgcag
121 ccagcaggct gcagctctgc cagtcagaga gggctggggc tggctggaat tgcagacaga
181 gggtggcact ggggagggct gtggggaagt ggggcttact caggcctctg atcaccttgc
241 cccagacact ggtgcaagtg gccatctatg ctctgggccg agagcccacc ttcttcttcg
301 acccggaaaa ttttgaccca acccgatggc tgagcaaaga caagaacatc acctacttcc
361 ggaacttggg ctttggctgg ggtgtgcggc agtgtctggg acggcggatc gctgagctag
421 agatgaccat cttcctcatc aatgtgagtc aagctgggga catctaggca ccctgggctg
481 ccctggccct aatgaaggca ccaatcttcc tcctcctatc tctgtcc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMCYP45I 682 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human gene for cholesterol desmolase cytochrome P-450 (SCC) exon 8
ACCESSION X05374
KEYWORDS cholesterol desmolase; cytochrome; cytochrome P-450;
cytochrome P-450 (SCC).
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 682)
AUTHORS Morohashi,K., Sogawa,K., Omura,T. and Fujii-Kuriyama,Y.
TITLE Gene Structure of Human Cytochrome P-450(SCC), Cholesterol
Desmolase
JOURNAL J. Biochem. 101, 879-887 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P05108; CPM1$HUMAN.
*source: clone=(lambda)hSCCE3-1; see x05367-73 for remaining exons
From EMBL entry HSCYP45I; dated 02-APR-1988.
FEATURES Location/Qualifiers
intron <1..213
/note="intron 8"
mRNA 214..>213
/note="exon 8"
CDS 214..342
/note="desmolase (exon 8) (AA 479-521)"
/codon_start=214
misc_feature 535..540
/note="polyA signal"
BASE COUNT 157 a 202 c 168 g 155 t
ORIGIN
1 agacaagtta aggtctaggc ctaaatcaag gaaatgcagc agcactaagg gtgcattatc
61 aggcactgtg cagggttaca ccaggagctg gtggtgaact ccttggaact cctcaaatca
121 cactccacag gcactgccta tgggtgaatt ggcctggcta gggagacaga tcctcccctg
181 ccctccccta aacctaccat ctgcctttct cagatgctgg agaacttcag agttgaaatc
241 caacacctca gcgatgtggg caccacattc aacctcattc tgatgcctga aaagcccatc
301 tccttcacct tctggccctt taaccaggaa gcaacccagc agtgatcaga gaggatggcc
361 tgcagccaca tgggaggaag gcccaggggt ggggccatgg ggtctctgca tcttcagtcg
421 tctgtcccaa gtcctgctcc tttctgccca gcctgctcag caggttgaat gggttctcag
481 tggtcacctt cctcagctca gctgggccat cctcttcacc caccccatgg agacaataaa
541 cagctgaacc atgtggtgtc ttgcgttcca tcagactcat taggtgttca tcactcccgt
601 ggagatgctt cctgtgttaa agcaggatct gggcatgctc aggagacccc aggtagccac
661 acttgaagcc acctctgctg gg
//