GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMERCC23 275 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Human genomic and mRNA sequence for ERCC2 gene 3'region involved in
DNA excision repair
ACCESSION X52222 X52470
KEYWORDS ATP-binding protein; DNA repair; DNA-binding protein; ERCC2 gene;
excision repair gene.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 275)
AUTHORS Weber,C.A.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 275)
AUTHORS Weber,C.A., Salazar,E.P., Stewart,S.A. and Thompson,L.H.
TITLE ERCC2: cDNA cloning and molecular characterisation of a human
nucleotide excision repair gene with high homology to yeast RAD3
JOURNAL EMBO J. 9, 1437-1447 (1990)
STANDARD full automatic
COMMENT *source: Genomic: developmental stage=adult; cell type=fibroblast;
*source: library=p5T4-1; clone=p5T4-1-7, p5T4-1-15 and p5T4-1-28;
**map: chromosome=19q13.2-q13.3; *source: mRNA: cell line=GM637;
library=pcD2; clone=pER2-14; Note sequence is compiled from both
genomic and cDNA sources. See <X52221> for 5'end of ERCC2.
From EMBL entry HSERCC23; dated 24-JUL-1990.
FEATURES Location/Qualifiers
intron <1..17
/note="intron II"
mRNA 18..51
/note="exon 3"
CDS 18..108
/note="ERCC2 gene product (AA 731-760) (18 is 2nd base in
codon)"
/codon_start=18
misc_feature 109..114
/note="polyA signal"
BASE COUNT 56 a 72 c 85 g 62 t
ORIGIN
1 cctcttgttc tctgcagagg atcagctggg cctgtccctg ctcagcctgg agcagctaga
61 atcagaggag acgctgaaga ggatagagca gattgctcag cagctctgag tggggcgggt
121 ggggccataa acggttcctg gtgactcctg agtcttgcct ggccctggtt cccagcggcg
181 gtggtgctag aaggtcttat gaagtcaggt gacatttctc actgtcacgt ccacagcctt
241 taatcgcagg agaaggcagc tatccaccag gtacc
//