GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMFOGBL 390 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Human mRNA for immunoglobulin lambda chain VJ region subgroup
lambda-1 (cell line Fog-B)
ACCESSION X52109
KEYWORDS immunoglobulin; immunoglobulin light chain; joining region;
variable region.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 390)
AUTHORS Hughes-Jones,N.C.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 390)
AUTHORS Hughes-Jones,N.C., Bye,J.M., Beale,D. and Coadwell,J.
TITLE Nucleotide sequences and three-dimensional modelling of the Vh and
Vl domains of two human monoclonal antibodies specific for the D
antigen of the human Rh-blood-group system.
JOURNAL Biochem. J. 268, 135-140 (1990)
STANDARD full automatic
COMMENT *source: strain=blood donor FO; cell type=B lymphocytes; *source:
cell line=Fog-B; **map: chromosome=22;
From EMBL entry HSFOGBL; dated 07-JUL-1990.
FEATURES Location/Qualifiers
CDS 1..>390
/note="precursor (AA -19 to 111)"
/codon_start=1
CDS 1..57
/note="signal peptide (AA -19 to -1)"
/codon_start=1
CDS 58..>390
/note="VJ region (AA 1-111)"
/codon_start=58
CDS 58..351
/note="V region (AA 1-98)"
/codon_start=58
CDS 352..>390
/note="J region (AA 99-111)"
/codon_start=352
BASE COUNT 82 a 128 c 96 g 84 t
ORIGIN
1 atgacctgct cccctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
61 tctgtgttga cgcagccgcc ctcagtgtct gcggccccag gacagaaggt caccatctcc
121 tgctccggaa ccagctccaa cattgggaat aattatgtat cctggtatca gcagctccca
181 ggaacagccc ccaaactcct catttatgac aataataagc gaccctcagg gattcctgac
241 cgattctctg gctccaagtc tggcacgtca gccaccctgg gcatcaccgg actccggact
301 ggggacgagg ccgattatta ctgcgcaaca tgggatagca gcctgagtgc tgtggtgttc
361 ggcggaggga ccaagctgac cgtcctaagt
//