GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMGCR 1776 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Human mRNA for group-specific component (GC)
ACCESSION X03178 M11321
KEYWORDS vitamin d-binding protein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1776)
AUTHORS Yang,F.
JOURNAL Unpublished (1985)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1776)
AUTHORS Yang,F., Brune,J.L., Naylor,S.L., Cupples,R.L., Naberhaus,K.H. and
Bowman,B.H.
TITLE Human group-specific component (Gc) is a member of the albumin
family
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 82, 7994-7998 (1985)
STANDARD full automatic
REFERENCE 3 (sites)
AUTHORS Yang,F., Luna,V.J., McAnelly,R.D., Naberhaus,K.H., Cupples,R.L. and
Bowman,B.H.
TITLE Evolutionary and structural relationships among the group-specific
component, albumin and alpha-fetoprotein
JOURNAL Nucleic Acids Res. 13, 8007-8017 (1985)
STANDARD full staff_review
COMMENT SWISS-PROT; P02774; VTDB$HUMAN.
From EMBL entry HSGCR; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 154..1575
/note="GC precursor (aa -16 to 458)"
/codon_start=154
CDS 154..201
/note="signal peptide (aa -16 to -1)"
/codon_start=154
CDS 202..1575
/note="mature GC (aa 1-458) vitamin D-binding protein"
/codon_start=202
BASE COUNT 544 a 393 c 369 g 470 t
ORIGIN
1 tttaataata attctgtgtt gcttctgaga ttaataattg attaattcat agtcaggaat
61 ctttgtaaaa aggaaaccaa ttacttttgg ctaccacttt tacatggtca cctacaggag
121 agaggaggtg ctgcaagact ctctggtaga aaaatgaaga gggtcctggt actactgctt
181 gctgtggcat ttggacatgc tttagagaga ggccgggatt atgaaaagaa taaagtctgc
241 aaggaattct cccatctggg aaaggaggac ttcacatctc tgtcactagt cctgtacagt
301 agaaaatttc ccagtggcac gtttgaacag gtcagccaac ttgtgaagga agttgtctcc
361 ttgaccgaag cctgctgtgc ggaaggggct gaccctgact gctatgacac caggacctca
421 gcactgtctg ccaagtcctg tgaaagtaat tctccattcc ccgttcaccc aggcactgct
481 gagtgctgca ccaaagaggg cctggaacga aagctctgca tggctgctct gaaacaccag
541 ccacaggaat tccctaccta cgtggaaccc acaaatgatg aaatctgtga ggcgttcagg
601 aaagatccaa aggaatatgc taatcaattt atgtgggaat attccactaa ttacggacaa
661 gctcctctgt cacttttagt cagttacacc aagagttatc tttctatggt agggtcctgc
721 tgtacctctg caagcccaac tgtatgcttt ttgaaagaga gactccagct taaacattta
781 tcacttctca ccactctgtc aaatagagtc tgctcacaat atgctgctta tggggagaag
841 aaatcaaggc tcagcaatct cataaagtta gcccaaaaag tgcctactgc tgatctggag
901 gatgttttgc cactagctga agatattact aacatcctct ccaaatgctg tgagtctgcc
961 tctgaagatt gcatggccaa agagctgcct gaacacacag taaaactctg tgacaattta
1021 tccacaaaga attctaagtt tgaagactgt tgtcaagaaa aaacagccat ggacgttttt
1081 gtgtgcactt acttcatgcc agctgcccaa ctccccgagc ttccagatgt agagttgccc
1141 acaaacaaag atgtgtgtga tccaggaaac accaaagtca tggataagta tacatttgaa
1201 ctaagcagaa ggactcatct tccggaagta ttcctcagta aggtacttga gccaacccta
1261 aaaagccttg gtgaatgctg tgatgttgaa gactcaacta cctgttttaa tgctaagggc
1321 cctctactaa agaaggaact atcttctttc attgacaagg gacaagaact atgtgcagat
1381 tattcagaaa atacatttac tgagtacaag aaaaaactgg cagagcgact aaaagcaaaa
1441 ttgcctgatg ccacacccaa ggaactggca aagctggtta acaagcgctc agactttgcc
1501 tccaactgct gttccataaa ctcacctcct ctttactgtg attcagagat tgatgctgaa
1561 ttgaagaata tcctgtagtc ctgaagcatg tttattaact ttgaccagag ttggagccac
1621 ccaggggaat gatctctgat gacctaacct aagcaaaacc actgagcttc tgggaagaca
1681 actaggatac tttctacttt ttctagctac aatatcttca tacaatgaca agtatgatga
1741 tttgctatca aaataaattg aaatataatg caaacc
//