GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMGSTPI4 725 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Human mRNA for anionic glutathione-S-transferase (GST-pi-1)
ACCESSION X15480
KEYWORDS anionic glutathione-S-transferase; drug resistance;
glutathione-S-transferase; multidrug resistance; transferase.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 725)
AUTHORS Moscow,J.A., Fairchild,C.R., Madden,M.J., Ransom,D.T., Wieand,H.S.,
O'Brien,E.E., Poplack,D.G., Cossman,J., Myers,C.E. and Cowan,K.H.
TITLE Expression of anionic Glutathione-S-transferase and P-Glycoprotein
genes in human tissues and tumors
JOURNAL Cancer Res. 49, 1422-1428 (1989)
STANDARD full automatic
COMMENT *source: cell line=multidrug resistant Adr(R) MCF cells; This
sequence is identical to (except base 572 which is C) sequence
<X06547>.
From EMBL entry HSGSTPI1; dated 21-SEP-1990.
FEATURES Location/Qualifiers
CDS 18..647
/note="glutathione-S-transferase pi-1"
/codon_start=18
misc_feature 705..710
/note="polyadenylation signal"
BASE COUNT 149 a 225 c 210 g 141 t
ORIGIN
1 ccgcagtctt cgccaccatg ccgccctaca ccgtggtcta tttcccagtt cgaggccgct
61 gcgcggccct gcgcatgctg ctggcagatc agggccagag ctggaaggag gaggtggtga
121 ccgtggagac gtggcaggag ggctcactca aagcctcctg cctatacggg cagctcccca
181 agttccagga cggagacctc accctgtacc agtccaatac catcctgcgt cacctgggcc
241 gcacccttgg gctctatggg aaggaccagc aggaggcagc cctggtggac atggtgaatg
301 acggcgtgga ggacctccgc tgcaaataca tctccctcat ctacaccaac tatgaggcgg
361 gcaaggatga ctatgtgaag gcactgcccg ggcaactgaa gccttttgag accctgctgt
421 cccagaacca gggaggcaag accttcattg tgggagacca gatctccttc gctgactaca
481 acctgctgga cttgctgctg atccatgagg tcctagcccc tggctgcctg gatgcgttcc
541 ccctgctctc agcatatgtg gggcgcctca gtgcccggcc caagctcaag gccttcctgg
601 cctcccctga gtacgtgaac ctccccatca atggcaacgg gaaacagtga gggttggggg
661 gactctgagc gggaggcaga gtttgccttc ctttctccag gaccaataaa atttctaaga
721 gagca
//