GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMHACHRB2 1771 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Human mRNA for neuronal nicotinic acetylcholine receptor beta-2
subunit
ACCESSION X53179
KEYWORDS acetylcholine receptor; nichotinic acetylcholine receptor;
transmembrane protein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1771)
AUTHORS Anand,R.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1771)
AUTHORS Anand,R. and Lindstrom,J.
TITLE Nucleotide sequence of the human nicotin acetylcholine receptor
beta-2 subunit gene
JOURNAL Nucleic Acids Res. 18, 4272-4272 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17787; ACHN$HUMAN.
*source: developmental stage=fetal; tissue=brain; *source: library=
lambda-zap, lambda-gt10 fetal brain cDNA; *source: cell type=
neuron; clone=HuMM1, HuWK1;
From EMBL entry HSHACHRB2; dated 26-JUL-1990.
FEATURES Location/Qualifiers
CDS 167..1672
/note="precursor peptide (AA -25 to 477)"
/codon_start=167
CDS 167..241
/note="signal peptide (AA -25 to -1)"
/codon_start=167
CDS 242..1672
/note="nichotinic acetylcholine receptor (AA 1-477)"
/codon_start=242
BASE COUNT 313 a 596 c 507 g 355 t
ORIGIN
1 gcagccggct ccctgaggcc caggaaccac cgcggcggcc ggcaccacct ggacccagct
61 ccaggcgggc gcggcttcag caccacggac agcgccccac ccgcggccct ccccccggcg
121 gcgcgctcca gccggtgtag gcgaggcagc gagctatgcc cgcggcatgg cccggcgctg
181 cggccccgtg gcgctgctcc ttggcttcgg cctcctccgg ctgtgctcag gggtgtgggg
241 tacggataca gaggagcggc tggtggagca tctcctggat ccttcccgct acaacaagct
301 tatccgccca gccaccaatg gctctgagct ggtgacagta cagcttatgg tgtcactggc
361 ccagctcatc agtgtgcatg agcgggagca gatcatgacc accaatgtct ggctgaccca
421 ggagtgggaa gattatcgcc tcacctggaa gcctgaagag tttgacaaca tgaagaaagt
481 tcggctccct tccaaacaca tctggctccc agatgtggtc ctgtacaaca atgctgacgg
541 catgtacgag gtgtccttct attccaatgc cgtggtctcc tatgatggca gcatcttctg
601 gctgccgcct gccatctaca agagcgcatg caagattgaa gtaaagcact tcccatttga
661 ccagcagaac tgcaccatga agttccgttc gtggacctac gaccgcacag agatcgactt
721 ggtgctgaag agtgaggtgg ccagcctgga cgacttcaca cctagtggtg agtgggacat
781 cgtggcgctg ccgggccggc gcaacgagaa ccccgacgac tctacgtacg tggacatcac
841 gtatgacttc atcattcgcc gcaagccgct cttctacacc atcaacctca tcatcccctg
901 tgtgctcatc acctcgctag ccatccttgt cttctacctg ccatccgact gtggcgagaa
961 gatgacgttg tgcatctcag tgctgctggc gctcacggtc ttcctgctgc tcatctccaa
1021 gatcgtgcct cccacctccc tcgacgtgcc gctcgtcggc aagtacctca tgttcaccat
1081 ggtgcttgtc accttctcca tcgtcaccag cgtgtgcgtg ctcaacgtgc accaccgctc
1141 gcccaccacg cacaccatgg cgccctgggt gaaggtcgtc ttcctggaga agctgcccgc
1201 gctgctcttc atgcagcagc cacgccatca ttgcgcccgt cagcgcctgc gcctgcggcg
1261 acgccagcgt gagcgcgagg gcgctggagc cctcttcttc cgcgaagccc caggggccga
1321 ctcctgcacg tgcttcgtca accgcgcgtc ggtgcagggg ttggccgggg ccttcggggc
1381 tgagcctgca ccagtggcgg gccccgggcg ctcaggggag ccgtgtggct gtggcctccg
1441 ggaggcggtg gacggcgtgc gcttcatcgc agaccacatg cggagcgagg acgatgacca
1501 gagcgtgagt gaggactgga agtacgtcgc catggtgatc gaccgcctct tcctctggat
1561 ctttgtcttt gtctgtgtct ttggcaccat cggcatgttc ctgcagcctc tcttccagaa
1621 ctacaccacc accaccttcc tccactcaga ccactcagcc cccagctcca agtgaggccc
1681 ttcctcatct ccatgctctt tcacccagcc accctctgct gcacagtagt gttgggtgga
1741 ggatggacga gtgagctacc aggaagaggg g
//