GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMHLABW 3840 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human HLA-Bw57 gene
ACCESSION X55711
KEYWORDS HLA-Bw57 gene; immunoglobulin; major histocompatability complex;
signal peptide.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3840)
AUTHORS Isamat,M.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 3840)
AUTHORS Isamat,M., Girdlestone,J. and Milstein,C.
TITLE Nucleotide sequence of an HLA-Bw57 gene
JOURNAL Nucleic Acids Res. 18, 6702-6702 (1990)
STANDARD full automatic
COMMENT *source: cell line=MOLT4; cell type=thymoma; library=lambda 2001.
From EMBL entry HSHLABW; dated 28-NOV-1990.
FEATURES Location/Qualifiers
mRNA join(<521..594,722..991,1238..1513,2089..2364,2469..2585,
3027..3059,3166..3213,3397..>3840)
exon <521..594
/number=1
exon <521..594
exon <521..594
prim_transcript <521..>3840
CDS join(<521..594,723..991,1238..1513,2089..2364,2469..2585,
3027..3059,3166..3209)
/codon_start=521
CAAT_signal 444..448
TATA_signal 470..474
intron 595..722
/number=1
exon 723..991
/number=2
exon 723..991
/note="alpha 1"
intron 992..1237
/number=2
exon 1238..1513
/number=3
exon 1238..1513
/note="alpha 2"
exon 1238..1513
intron 1514..2088
/number=3
exon 2089..2364
/number=4
exon 2089..2364
/note="alpha 3"
exon 2089..2364
intron 2365..2468
/number=4
exon 2469..2585
/number=5
exon 2469..2585
/note="alpha 4"
exon 2469..2585
intron 2586..3026
/number=5
exon 3027..3059
/number=6
exon 3027..3059
/note="alpha 5"
exon 3027..3059
intron 3060..3165
/number=6
exon 3166..3213
/number=7
/note="alpha 6"
exon 3166..3213
intron 3214..3396
/number=7
exon 3397..>3801
/number=8
/note="untranslated exon"
BASE COUNT 741 a 1079 c 1191 g 829 t
ORIGIN
1 gagctcactc tctggcatca agttctccgt gatcagtttc cctacacaag atccaagagg
61 agaggtaagg agtgagaggc agggagtcca gttcagggac agggattcca ggaggagaag
121 tgaaggggaa gcgggtgggc gctcagcctg ggggtctctc cctggtttcc acagacagat
181 ccttgtgcag gactcaggca gacagtgtga caaagaggct ggtgtaggag aagagggatc
241 aggacgaagt cccaggtccc ggacggggct ctcagggtct caggctccga gagccttgtc
301 tgcattgggg aggcgcagcg ttggggattc cccactccca cgagtttcac ttcttctccc
361 aacctgtgtc gggtccttct tccaggatac tcgtgacgcg tccccatttc ccactcccat
421 tgggtgtcgg gtgtctagag aagccaatca gcgtcgccgc ggtcccagtt ctaaagtccc
481 cacgcaccca cccggactca gaatctcctc agacgccgag atgcgggtca cggcaccccg
541 aaccgtcctc ctgctgctct ggggggcagt ggccctgacc gagacctggg ccggtgagtg
601 cgggtcggca gggaaatggc ctctgtaggg aggagcaagg ggaccgcagg cgggggcgca
661 ggacccgggg agccgcgccg ggaggagggt cgggcgggtc tcagcccctc ctcgccccca
721 ggctcccact ccatgaggta tttctacacc gccatgtccc ggcccggccg cggggagccc
781 cgcttcatcg cagtgggcta cgtggacgac acccagttcg tgaggttcga cagcgacgcc
841 gcgagtccga ggatggcgcc ccgggcgcca tggatagagc aggaggggcc ggagtattgg
901 gacggggaga cacggaacat gaaggcctcc gcgcagactt accgagagaa cctgcggatc
961 gcgctccgct actacaacca gagcgaggcc ggtgagtgac cccggcccgg ggcgcaggtc
1021 acgactcccc atcccccacg tacggcccgg gtcgccccga gtctccgggt ccgagatcca
1081 cccccctgag gccgcgggac ccgcccagac cctcgaccgg cgagagcccc aggcgcgttt
1141 acccggtttc attttcagtt gaggccaaaa tccccgcggg ttggtcaggg cggggcgggg
1201 ctcgggggga cggggctgac cgcggggccg gggccagggt ctcacatcat ccaggtgatg
1261 tatggctgcg acgtggggcc ggacgggcgc ctcctccgcg ggcatgacca gtccgcctac
1321 gacggcaagg attacatcgc cctgaacgag gacctgagct cctggaccgc ggcggacacg
1381 gcggctcaga tcacccagcg caagtgggag gcggcccgtg tggcggagca gctgagagcc
1441 tacctggagg gcctgtgcgt ggagtggctc cgcagatacc tggagaacgg gaaggagacg
1501 ctgcagcgcg cgggtaccag gggcagtggg gagccttccc catctcctat aggtcgccgg
1561 ggatggcctc ccacgagaag aggaggaaaa tgggatcagc gctagaatgt cgccctccct
1621 tgaatggaga atggcatgag ttttcctgag tttcctctga gggccccctc ttctctctag
1681 gacaattaag ggatgacgtc tctgaggaaa tggaggggaa gacagtccct agaatactga
1741 tcaggggtcc cctttgaccc ctgcagcagc cttgggaacc gtgacttttc ctctcaggcc
1801 ttgttctctg cctcacactc agtgtgtttg gggctctgat tccagcactt ctgagtcact
1861 ttacctccac tcagatcagg agcagaagtc cctgttcccc gctcagagac tcgaactttc
1921 caatgaatag gagattatcc caggtgcctg cgtccaggct ggtgtctggg ttctgtgccc
1981 cttccccacc ccaggtgtcc tgcccattct caggctggtc acatgggtgg tcctagggtg
2041 tcccatgaga gatgcaaagc gcctgaattt tctgactctt cccatcagac cccccaaaga
2101 cacatgtgac ccaccacccc atctctgacc atgaggccac cctgaggtgc tgggccctgg
2161 gcttctaccc tgcggagatc acactgacct ggcagcggga tggcgaggac caaactcagg
2221 acaccgagct tgtggagacc agaccagcag gagatagaac cttccagaag tgggcagctg
2281 tggtggtgcc ttctggagaa gagcagagat acacatgcca tgtacagcat gaggggctgc
2341 caaagcccct caccctgaga tggggtaagg agggggatga ggggtcatat ctcttctcag
2401 ggaaagcagg agcccttctg gagcccttca gcagggtcag ggcccctcat cttcccctcc
2461 tttcccagag ccatcttccc aatccaccgt ccccatcgtg ggcattgttg ctggcctggc
2521 tgtcctagca gttgtggtca tcggagctgt ggtcgctgct gtgatgtgta ggaggaagag
2581 ctcaggtagg gaaggggtga ggggtggggt ctgggttttc ttgtcccact gggggtttca
2641 agccccaggt agaagtgttc cctgcctcat tactgggaag cagcatgcac acaggggcta
2701 acgcagcctg ggaccctgtg tgccagcact tactcttttg tgcagcacat gtgacaatga
2761 aggacggatg tatcacctcg atggttgtgg tgttggggtc ctgattccag cattcatgag
2821 tcaggggaag gtccctgcta aggacagacc ttaggagagc agttggtcca ggacccacac
2881 ttgctttcct cgtgtttcct gatcctgccc tgggtctgta gtcatacttc tggaaattcc
2941 ttttgggtcc aagacgagga ggttcctcta agatctcatg gccctgcttc ctcccagtcc
3001 cctcacagga cattttcttc ccacaggtgg aaaaggaggg agctactctc aggctgcgtg
3061 taagtggtgg gggtgggagt gtggaggagc tcacccaccc cataattcct cctgtcccac
3121 gtctcctgcg ggctctgacc aggtcctgtt tttgttctac tccaggcagc gacagtgccc
3181 agggctctga tgtgtctctc acagcttgaa aaggtgagat tcttggggtc tagagtgggt
3241 gggggtggcg ggtctggggc ggggtggggc agaggggaaa ggcctgggta atggagattc
3301 tttgattggg atgtttcgcg tgtgtggtgg gctgttcaga gtgtcatcac ttaccatgac
3361 tcaccagaat ttgttcatga ctgttgtttt ctgtagcctg agacagctgt cttgtgaggg
3421 actgagatgc aggatttctt cacgcctccc ctttgtgact tcaagagcct ctggcatctc
3481 tttctgcaaa ggcacctgaa tgtgtctgcg tccctgttag cctaatgtga ggaggtggag
3541 agacagccca accttgtgtc cactgtgacc cctgttccca tgctgacctg tgtttcctcc
3601 ccagtcatct ttcttgttcc agagaggtgg ggctggatgt ctccatctct gtctcaactt
3661 tatgtgcact gagctgcaac ttcttacttc cctgctgaaa ataagaatct gaatatcaat
3721 ttgttttctc aaatatttgc tatgagaggt tgatggatta attaaataag tcaattcctg
3781 gaatttgaga gagcaaataa agacctgaga accttccaga atctgcatgt tcgctgtgct
//