GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMHLDC2 1116 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Human mRNA for DC classII histocompatibility antigen alpha-chain
ACCESSION X00452
KEYWORDS histocompatibility antigen; signal peptide.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1116)
AUTHORS Auffray,C., Lillie,J.W., Arnot,D., Grossberger,D., Kappes,D. and
Strominger,J.L.
TITLE Isotypic and allotypic variation of human class II
histocompatibility antigen alpha-chain genes
JOURNAL Nature 308, 327-333 (1984)
STANDARD full automatic
COMMENT SWISS-PROT; P01907; HA25$HUMAN.
From EMBL entry HSHLDC2; dated 13-JUN-1985.
FEATURES Location/Qualifiers
CDS 23..91
/note="signal peptide"
/codon_start=23
CDS 92..352
/note="alpha 1 domain"
/codon_start=92
CDS 353..644
/note="alpha 2 domain"
/codon_start=353
CDS 645..673
/note="(CP) connecting peptide"
/codon_start=645
CDS 674..742
/note="(TM) transmembrane region"
/codon_start=674
CDS 743..787
/note="(CY) cytoplasmatic region"
/codon_start=743
misc_feature 1100..1105
/note="polyadenylation signal"
polyA_site 1116..1116
/note="polyadenylation site"
BASE COUNT 252 a 301 c 258 g 305 t
ORIGIN
1 ctgaggctgc cttgggaaga agatgatcct aaacaaagct ctgctgctgg gggccctcgc
61 tctgaccacc gtgatgagcc cctgtggagg tgaagacatt gtggctgacc acgttgcctc
121 ttgtggtgta aacttgtacc agttttacgg tccctctggc cagtacaccc atgaatttga
181 tggagatgag cagttctacg tggacctgga gaggaaggag actgcctggc ggtggcctga
241 gttcagcaaa tttggaggtt ttgacccgca gggtgcactg agaaacatgg ctgtggcaaa
301 acacaacttg aacatcatga ttaaacgcta caactctacc gctgctacca atgaggttcc
361 tgaggtcaca gtgttttcca agtctcccgt gacactgggt cagcccaaca ccctcatttg
421 tcttgtggac aacatctttc ctcctgtggt caacatcaca tggctgagca atgggcagtc
481 agtcacagaa gatgtttctg agaccagctt cctctccaag agtgatcatt ccttcttcaa
541 gatcagttac ctcaccttcc ttccctctgc tgatgagatt tatgactgca aggtggagca
601 ctggggcctg gaccagcctc ttctgaaaca ctgggagcct gagattccag cccctatgtc
661 agagctcaca gagactgtgg tctgtgccct ggggttgtct gtgggcctca tgggcattgt
721 ggtgggcact gtcttcatca tccaaggcct gcgttcagtt ggtgcttcca gacaccaagg
781 gccattgtga atcccatcct ggaagggaag gtgcatcgcc atctacagga gcagaagaat
841 ggacttgcta aatgacctag cactattctc tggcccggtt tatcatatcc cttttctcct
901 ccaaatattt ctcctctcac cttttctctg ggacttaagc tgctatatcc cctcagagct
961 cacaaatgcc tttacattct ttccctgacc tcctgatttt tttttctttt ctcaaatgtt
1021 acctacacag acatgcctgg ggtaagccac ccggctacct aattcctcag taacctccat
1081 ctaaaatctc caaggaagca ataaattcct tttatg
//