GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMIFNH 5961 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human immune interferon (IFN-gamma) gene.
ACCESSION V00536
KEYWORDS interferon.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 5961)
AUTHORS Gray,P.W. and Goeddel,D.V.
TITLE structure of the human immune interferon gene
JOURNAL Nature 298, 859-863 (1982)
STANDARD full automatic
COMMENT EPD; 07113; Hs g'-interferon.
From EMBL entry HSIFNG; dated 26-NOV-1990.
FEATURES Location/Qualifiers
precursor_RNA 347..5319
/note="primary transcript"
mRNA 347..588
/note="messenger RNA (exon 1)"
CDS 475..588
/note="interferon (part 1)"
/codon_start=475
mRNA 1828..2174
/note="messenger RNA (exon 2)"
CDS 1828..2174
/note="interferon (part 2)"
/codon_start=1828
mRNA 4600..5319
/note="messenger RNA (exon 3)"
CDS 4600..4731
/note="interferon (part 3)"
/codon_start=4600
polyA_site 5319..5319
/note="polyA addition site"
BASE COUNT 1829 a 1012 c 1170 g 1950 t
ORIGIN
1 agcaaatgat caatgtgctt tgtgaatgaa gagtcaacat tttaccaggg cgaagtgggg
61 aggtacaaaa aaatttccag tccttgaatg gtgtgaagta aaagtgcctc aaagaatccc
121 accagaatgg cacaggtggg cataatgggt ctgtctcatc gtcaaaggac ccaaggagtc
181 taaaggaaac tctaactaca acacccaaat gccacaaaac cttagttatt aatacaaact
241 atcatccctg cctatctgtc accatctcat cttaaaaaac ttgtgaaaat acgtaatcct
301 caggagactt caattaggta taaataccag cagccagagg aggtgcagca cattgttctg
361 atcatctgaa gatcagctat tagaagagaa agatcagtta agtcctttgg acctgatcag
421 cttgatacaa gaactactga tttcaacttc tttggcttaa ttctctcgga aacgatgaaa
481 tatacaagtt atatcttggc ttttcagctc tgcatcgttt tgggttctct tggctgttac
541 tgccaggacc catatgtaaa agaagcagaa aaccttaaga aatattttgt aagtatgact
601 ttttaatagt acttgtttgt ggttgaaaat gactgaatat cgacttgctg tagcatctct
661 gataggctgt catctcttgt aggcagtcat tttgagattt ggtgttattt tgttaattat
721 tgactagatg agttccttga ctaaataatc tagatattgt tttaaccttc tgctcagttt
781 gtatagagac ttaaaaggga tttatgaatt ttccaaaaga tgggcataat atgggtatga
841 agcataatga tgttaataat tttgtggtgg gaactcattc agttgtgata gtcaaggagt
901 atgcagattg aaaaaaatga ttggttatta gtttttgact tctcagactc taaggtcaag
961 attagcatta aaaaggtaat aggaaatgtt tacaaattaa agtcaaaaag gtccttaaag
1021 ctttggctta aaaaaataac tgataggtga ttttctccaa aaagtgattt caacattctg
1081 cttctctatc tatattactt gtgaagtatt ccggaacttc gttgctcact gggattttgg
1141 aagaattatg attctggcta aggaatgttt aaaaatttta agtgaatttt ttgagtttct
1201 tttaaaattt tattgatggt taatgaaaag tttttacatt ttaaatattt cattatttgt
1261 ttaaaactta gctgttataa ttatagctgt cataataata ttcagacatt cacaattgat
1321 tttattctta caacacaaaa tcaaatctca cacacacaca cacacacaca cactcgcaca
1381 tgtttggaac tatcttttaa agctcgtata ataataccct acaggaaggc acagtagatg
1441 taatagaaac ctgtaccatt ggggggcagt attttatagt ggggtggctt tgctgttttt
1501 tgtttttgta ttttttagcc tagcttgaaa atactttctt tagcttacta tagtttttgg
1561 gacctttgga gtatcagctt tgttgagctc atttgtgaca ttgcaattta atggttatat
1621 tgggaaataa aaaagctaaa agaacataat agtctttgtc tatatctcac ataagccttt
1681 tgggaatact tattgttaga actaagcaga agagttgaaa aggaaatcag tgaatattgt
1741 cacatctgag ttcaatgaaa cttgaaatat atttttaagg caatttatgg gctaattgta
1801 aaccaatttt ttcttttttt tttttagaat gcaggtcatt cagatgtagc ggataatgga
1861 actcttttct taggcatttt gaagaattgg aaagaggtaa gctgaatatt cccatttggc
1921 taattttcct gttgcttgct ttctgatgga taaattcaca tcatcctctg tttgtgctct
1981 ttccttccaa ggagagtgac agaaaaataa tgcagagcca aattgtctcc ttttacttca
2041 aactttttaa aaactttaaa gatgaccaga gcatccaaaa gagtgtggag accatcaagg
2101 aagacatgaa tgtcaagttt ttcaatagca acaaaaagaa acgagatgac ttcgaaaagc
2161 tgactaatta ttcggtgagg ctatttaaat tctttctttg gtttcattgc cgagggtctt
2221 gcaaagcatt tattctccag aaagtagaca ttagctattt aacagttgct aaagctatga
2281 actcaactca tggctgaaac tctaccttac tatttccatt cgtgtttggg tgactttgca
2341 aagccagtaa gagaatcgct gaagtatgta atgtagagaa atgctggcat tgtaactatt
2401 gcgtaaagac aggtgagttg acaaattcca gtgaagagga agtaggtgag gaagaagcag
2461 ggagtactga gaagcagttc tctcattgtc ccttgctcat atgatggaaa ttctcttact
2521 ttgaatgaga ggctgtctgt cttaatggaa agagcagtgg gaggagctga gaagatgtgt
2581 gttctcctcc caactcagcc accaaggaac tgtgatgaat cacatggctg gctgggctca
2641 gtttcctcat cttaaaagga aactgttagg ttcactgtat aagtttgatg accttctttg
2701 ctccaaaact ctacaatgca aagaatagaa aatgagaatg agatagaaga aagctacagt
2761 ctttgaatag gtaccaggga caccccactg caagtctcta gccaacctat cagattgtac
2821 tgcccaatta gaagcaagaa tggttgctgt ttgtttgttt ttagggaaaa atagatagaa
2881 tttatacctt atgaaaagat tgttctatca actctctatc aactttcaga atatctcagc
2941 tggagaactc cttagactcc taagtcttac ctcatgaact tgtatcttta agttatggct
3001 tctataaaca gaaagataac gttgaggcat aaagacaaat catgtttttc agaatgtttt
3061 ctagaagaca aaggcctcta gattcctttg gggttgactt tgatataaat gggctcaaat
3121 gagagggacc agggtcttca agctagcatt tgtgttctta ggatatgtgc tcagctttca
3181 ctattgctgg gcctgcctct cactcctctc atgtaagccc ccagaaacag aaaggagaga
3241 catggcaaca ggtctccttt ggttataaac tagacactca gcacttgttt ctaatccagt
3301 ggtgcccctg gcttactgtt cagtcctgga taagtctctt agtttcttgg tgatgatttg
3361 aacattggaa agtaaaatct gtcacttgca aacacacagc ttgtcgaaaa ttttttctac
3421 tctgcaggaa ctgggcctta aaaaaatgaa aaaaaatctg tggtttcttc cttctggaag
3481 ctacaaacct cctgtttctt gatgggcaat cttgagtgag ctctattaat tattattctc
3541 tttggctcag ttgctaagct attttatgca tgttatgccc tttgacaatt agtctttagc
3601 tgtaatcccc cagccatcct cagaaatgtg gtgaggtagc catagtgttc ccaagattag
3661 aaaaatgtaa tggcagagcc aagaggaagg taaatggtcc acatcttatg aagcatcatc
3721 taaatggccc tattggttag agtgaggaga tgcaagtagt tcaatttgct tgcctagaag
3781 gcagggtact ggaaaagttg ttgcaattct taattttaaa ctttatatat cagtaagcca
3841 tatataaata tgattggggg tgtttatttt aaaatctatt atggaaattg agagactgac
3901 ctaatctggg agaaattaaa aattacagtt ttcactcgtt ttggatttgg tgttttctag
3961 ggtacctaac ctagatcagt ggttctcaaa cttaggtgga tgtcagaatc acctggggag
4021 cttagtgaat gcacagggca cagtccttcc acttcatgca cctggatctc tgaggtcttt
4081 gacaggtttc cggattaatc tgctatgcac aacagtgaga atcattgacc tatagttact
4141 catttgatgc atacaggaaa gactgaagta taaagtgata taattggtag attgatgata
4201 gagaggtcat agaaacagtc tcatcctcct ttagatgaga aaatagaagt tcagagaggt
4261 taagtagctg gctcaaggtc agaattattg catgcatgag attcaaaccc acctttttat
4321 gctgactcca caaccaggag tcttttcact atataatttc aagaattcta tagaagtaga
4381 tttaaagata tgtgatggac tccaccacat tatagcacaa ctagaaatgt aattgtaatt
4441 tttagcttca actgctgaag aagtaaatat tgtatattaa ggtaatacgg tccatttttt
4501 aaaggaatac ttttattttc actgaccatc atgacattag cagaatatcc tgatggctta
4561 tatgcctgaa attaattttg ctcttttctt tcccgatagg taactgactt gaatgtccaa
4621 cgcaaagcaa tacatgaact catccaagtg atggctgaac tgtcgccagc agctaaaaca
4681 gggaagcgaa aaaggagtca gatgctgttt cgaggtcgaa gagcatccca gtaatggttg
4741 tcctgcctgc aatatttgaa ttttaaatct aaatctattt attaatattt aacattattt
4801 atatggggaa tatattttta gactcatcaa tcaaataagt atttataata gcaacttttg
4861 tgtaatgaaa atgaatatct attaatatat gtattattta taattcctat atcctgtgac
4921 tgtctcactt aatcctttgt tttctgacta attaggcaag gctatgtgat tacaaggctt
4981 tatctcaggg gccaactagg cagccaacct aagcaagatc ccatgggttg tgtgtttatt
5041 tcacttgatg atacaatgaa cacttataag tgaagtgata ctatccagtt actgccggtt
5101 tgaaaatatg cctgcaatct gagccagtgc tttaatggca tgtcagacag aacttgaatg
5161 tgtcaggtga ccctgatgaa aacatagcat ctcaggagat ttcatgcctg gtgcttccaa
5221 atattgttga caactgtgac tgtacccaaa tggaaagtaa ctcatttgtt aaaattatca
5281 atatctaata tatatgaata aagtgtaagt tcacaactac ttatgctgtg ttggactttt
5341 tctaagtgag acctggagtg aaagaactac ctattaatga attagtaggg aggggagtct
5401 tcttagctgt gaaaatttta gagttgcatt tggttccatt aaatgtggta tttctttcca
5461 ctagcatttt gttggctttc gcttttccag ttagcagctc tttgaattat ctttctaaga
5521 tacagattta attatgtcac tattcaattc agaggttctg ctatggaatg tagtttaaac
5581 tgcttagctt ggcacacaga gatttatttc tagccccttc tccaccttcc tatttcctcc
5641 ttcgtttcag aatcttcctc tccctcatcc aatgctggca aacaccagtg ggggtggagt
5701 agtgggtgta agctctaggg agaaggcttg gattggaatc caagttattc cattacaagt
5761 agtgtgacct ttaatacatt atgtatattg tctaagtttc agctttattg tctgaaaaag
5821 aaaaataatt gtgtgttcct cataatattg tggtacgaat tgattctttc actcaagaaa
5881 tatttactgg agtacctact acatgcctgg tgctgttgta gaccttgaga taccttactc
5941 aagcaaaaca gccaaggatc c
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