GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMIGE38A 2739 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human IgE switch region (S epsilon)
ACCESSION X56797
KEYWORDS IgE switch region; immunoglobulin.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2739)
AUTHORS Mills,F.C.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Mills,F.C., Brooker,J.S. and Camerini-Otero,R.D.
TITLE Sequences of human immunoglobulin switch regions: implications for
recombination and transcription
JOURNAL Nucleic Acids Res. 18, 7305-7316 (1990)
STANDARD full staff_review
COMMENT *source: tissue=liver; developmental stage=fetus; *source: library=
lambda Charon 28; clone=lambda 38A. **map: map position=14q32.3.
See also <J00222> and <K01241> for related sequences.
From EMBL entry HSIGE38A; dated 31-DEC-1990.
FEATURES Location/Qualifiers
misc_feature 405..538
/note="mouse/human ECS"
misc_feature 420..429
/note="MHC X box"
CAAT_signal 430..435
misc_feature 450..463
/note="potential ISRE"
protein_bind 466..477
/bound_moiety="SP1"
misc_feature 506..590
/note="sterile transcription start sites"
misc_feature 1201..2739
/note="Smu homology"
BASE COUNT 563 a 665 c 972 g 539 t
ORIGIN
1 ggatccccgg ctgcaggaca gtgacctggg agtgagtaca aggtgaggcc accactcagg
61 gtgccagctc caagcgggtc acagggacga gggctgcggc catcaggagg ccctgcacac
121 acatctggga cacgcgcccc gagggccagt tcacctcagt gcgcctcatt ctcctgcaca
181 aaagcgcccc catcctttct tcacaaggct ttcgtggaag cagaggcgtc gatgcccagt
241 accctctccc tttcccaggc aacgggaccc caagtttgct gactgggacc accaagccac
301 gcatgcgtca agagtagagt ccgggaccta ggcaggggcc ctggcgttgg gcctgagaga
361 gaagagaacc tccccagcac tcggtgtgca tcggtagtga accagcctca cctgaccccc
421 gctgttgctc aatcgacttc ccaagaacag agagaaaagg gaacttccag ggcggcccgg
481 gcctcctggg gttcccaccc catttttagc tgaaagcact gaggcagagc tccccctacc
541 caggctccac tgcccggcac agaaataaca accacggtta ctgatcatct gggagctgtc
601 caggaacccg acagagccgg agggccacac atccacaggc accaaatgga cgacccggcg
661 cttcaggtat cccagcccac cggagcccca atcgaggggc cgggaggcag ctgtgaggga
721 gaggctgcct gggccctgac agcgagggac tcctgggcca cctcacagca tcaaccaagc
781 ttcttggtca ctgcgtggac tctaggcact cccttccctg catggggaca caggaaagct
841 agaaacagcc taatgccgac ctggagaagg cagggggctg ggaatcttgc tggccaagac
901 caagaagtca gagacccgac tggcagggct ggctggtgca gactgcctgc cacccctagg
961 acaggacagc caacccagag ctggaaggga gggtggggag gcggcagcag ggagctgtcc
1021 tgagctccac tgcgcaactg gctgatcttg gcaagtccga gctgggcgac tgaggggggc
1081 ttggctgagt ggactagact gagacgggcc taacagactg agctgaggcg agctgggtgg
1141 gctgagaggg ctacctgtcc cttagaggac aggtggccaa gctgggctgt cctgagccag
1201 ggcgatcggg gctggcccgg gccaggcggg tttagctgag ttgagtgagt ggactgggta
1261 gagggaaatg agctaggctc agctgagcta ggcttgagct gggttatcct aagccctaag
1321 gtggactagc tgggctgagc tggacttatc tgggcaggca aagtcaggct gagctgaggt
1381 ggcctccctg gtggtccaga ttgagttaag ctgaattagg ctgacctgga cttggttgaa
1441 ataagctggg ccgacacagg agtagggaca actacagttc tctacttagg ataaaatggg
1501 tgctcgtgga ctatccgggc tgaaggagac caagctgggg tattacctgc tgagttacct
1561 gacctggcct gagttcagcc gcgtgcgctg agctggacag acctgagcca agcttagctg
1621 gttgggctga gtaactgggc tgagctaaat gggattgagc tgaggagggc taggctgggg
1681 gagagactga cgacggacag ggttaaaagc tggagtgagc aggccttaaa ttgggctggg
1741 gtgatctgaa tttagctggg atgagctggg ctgggctgaa ctgtgcccac gtgaactggg
1801 ctaaactagg ctcgctgagt ggactcagct gggttggtct ctcgggttca gctgggctgg
1861 gctgagctag gttagactgg gaagctgggc tgggttgggc tgggttgggc tgggctgctc
1921 taggctaagc taacctaacc taacctgggt tcagctggcc taggttgggc tgggttgggc
1981 taaagtccct tcagctgaga tatgctaata tgggctgggc tgggtcaggt tgaggttaac
2041 tgaactgggc tgacctgggc tgagctcaac tgagttcaca tgggctgggc tggcctggcc
2101 tgggcctaaa ctgggtttgg ctgggctggg ccaactggac tgaggtggat ggagctgggc
2161 tgagctggcc tggccgggcc tgagctgtga ttggaagacc tgggctgagc tggacagacc
2221 tgagccaagc ttagctagtt gggctgacta agctggtttg ggctaaactg ggtgagctgg
2281 ggaggactag gctgggtgag tgacctgaga tggacagggt tataagaagc tggactgagc
2341 tgggcttgga ttattgaacc gaattgggtt ggggtgattt aaactgagtt ctgctgggat
2401 aagctgatct actctgggct gaactgagca gagctgaacc tagctgggct gggctaaact
2461 gggctagcct gagctgggct gaactgggct gctgggctgg actgggtaag ctgggctgag
2521 ctgggttggg tggaaatggg ctgagctgag ctaggctaaa ctgggtttgg ctgggctggg
2581 ctgggctggg ctgggttcag ctgagcgggt tgggttagac tgggtcaaac tggttcagct
2641 gagatgggct gatatgagct gggctgggcc aggctgagct cagctaaact gggcagtgct
2701 ggactgggct gagctagact gggcaactgt attcagctg
//