GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMIGKLC1 797 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human germline fragment for immunoglobulin kappa light chain
(subgroup III variable region gene V(g)
ACCESSION X01668
KEYWORDS immunoglobulin; immunoglobulin light chain; kappa-immunoglobulin;
variable region.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 797)
AUTHORS Pech,M. and Zachau,H.G.
TITLE Immunoglobulin genes of different subgroups are interdigitated
within the VK locus
JOURNAL Nucleic Acids Res. 12, 9229-9236 (1984)
STANDARD full automatic
COMMENT From EMBL entry HSIGKLC1; dated 07-NOV-1985.
FEATURES Location/Qualifiers
misc_feature 2..16
/note="pentekaideca nucleotide box (pd)"
misc_feature 31..40
/note="deca nucleotide box (dc)"
promoter 73..80
/note="pot. TATA-box"
CDS 134..182
/note="pot. signal peptide (aa -20 to -5) (182 is 1st base
in codon)"
/codon_start=134
intron 183..351
/note="pot. intron"
misc_feature 199..200
/note="pot. alternative donor splice site"
CDS 352..362
/note="pot. signal peptide (aa -4 to -1) (352 is 2nd base
in codon) (362 is 2nd base in codon)"
/codon_start=352
CDS 363..431
/note="pot. framework 1, FR1"
/codon_start=363
CDS 432..464
/note="pot. complentarity determining region 1, CDR1"
/codon_start=432
CDS 465..509
/note="pot. FR2"
/codon_start=465
CDS 510..530
/note="pot. CDR2"
/codon_start=510
CDS 531..626
/note="pot. FR3"
/codon_start=531
CDS 627..647
/note="pot. CDR3"
/codon_start=627
misc_feature 650..656
/note="hepta nucleotide box"
misc_feature 669..677
/note="nona nucleotide box"
BASE COUNT 196 a 223 c 174 g 204 t
ORIGIN
1 ctgcagctgg aagctcagct cccacccagc tgctttgcat gtccctccca gctgccctac
61 cttccagagc ccatatcaat gcctgtgtca gagccctggg gaggaactgc tcagttagga
121 cccagaggga accatggaag ccccagctca gcttctcttc ctcctgctac tctggctccc
181 aggtgagggg aacatgaggt ggttttgcac attagtgaaa actcttgcca cctctgctca
241 gcaagaaata taattaaaat tcaaagtata tcaacaattt tggctctact caaagacagt
301 tggtttgatc ttgattacat gagtgcattt ctgttttatt tccaatttca gataccaccg
361 gagaaattgt gttgacacag tctccagcca ccctgtcttt gtctccaggg gaaagagcca
421 ccctctcctg cagggccagt cagagtgtta gcagctactt agcctggtac caacagaaac
481 ctggccaggc tcccaggctc ctcatctatg atgcatccaa cagggccact ggcatcccag
541 ccaggttcag tggcagtggg tctgggacag acttcactct caccatcagc agcctagagc
601 ctgaagattt tgcagtttat tactgtcagc agcgtagcaa ctggcctccc acagtgattc
661 cacatgaaac aaaaacccca acaagaccat cagtgtttac tagattatta taccagctgc
721 ttcctttaca gacagctagt ggggtggcca ctcagtgtta gcatctcagc tctatttggc
781 cattttggag ttcaagt
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMIGKLC2 716 bp ds-DNA PRI 27-MAY-1991
DEFINITION Human germline fragment for immunoglobulin kappa light chain
(subgroup III) variable region gene V(h)
ACCESSION X02725
KEYWORDS immunoglobulin; immunoglobulin light chain; kappa-immunoglobulin;
variable region.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 716)
AUTHORS Pech,M. and Zachau,H.G.
TITLE Immunoglobulin genes of different subgroups are interdigitated
within the VK locus
JOURNAL Nucleic Acids Res. 12, 9229-9236 (1984)
STANDARD full automatic
COMMENT From EMBL entry HSIGKLC2; dated 07-NOV-1985.
FEATURES Location/Qualifiers
misc_feature 2..16
/note="pentekaideca nucleotide box (pd)"
misc_feature 31..40
/note="deca nucleotide box (dc)"
promoter 73..80
/note="pot. TATA-box"
CDS 134..182
/note="pot. signal peptide (aa -20 to -5) (182 is 1st base
in codon)"
/codon_start=134
intron 183..351
/note="pot. intron"
misc_feature 199..200
/note="pot. alternative donor splice site"
misc_feature 350..351
/note="pot. acceptor splice site violating GTAG rule"
CDS 352..362
/note="pot. signal peptide (aa -4 to -1) (352 is 2nd base
in codon)"
/codon_start=352
CDS 363..431
/note="pot. framework 1 FR1"
/codon_start=363
CDS 432..467
/note="pot. complementarity determining region CDR1"
/codon_start=432
CDS 468..512
/note="pot. FR2"
/codon_start=468
CDS 513..533
/note="pot. CDR2"
/codon_start=513
CDS 534..629
/note="pot. FR3"
/codon_start=534
CDS 630..650
/note="pot. CDR3"
/codon_start=630
misc_feature 653..659
/note="heptanucleotide box"
misc_feature 672..680
/note="nonanucleotide box"
BASE COUNT 184 a 207 c 151 g 174 t
ORIGIN
1 ctgcagctgg aagctcagct cccacccagc tgctttgcat gtccctccca gctgccctac
61 cttccagagc ccatatcaat gcctgggtca gagccctggg aaggaactgc tcagttagga
121 cccagacgga accatggaag ccccagctca gcttctcttc ctcctgctac tctggctccc
181 aggtgagggg aacatgaggt ggttttgcac atcagtgaaa actcctgcca cctctgctca
241 gcaagaaata taattaaaat tcaatgtaga tcaacaattt tggctctact caaagacagc
301 tggtttgatc tagattacat gagtgcattt ctgttttatt tccaatcttg gataccacca
361 gagaaattgt aatgacacag tctccaccca ccctgtcttt gtctccaggg gaaagagtca
421 ccctctcctg cagggccagt cagagtgtta gcagcagcta cttaacctgg tatcagcaga
481 aacctggcca ggcgcccagg ctcctcatct atggtgcatc caccagggcc actagcatcc
541 cagccaggtt cagtggcagt gggtctggga cagacttcac tctcaccatc agcagcctgc
601 agcctgaaga ttttgcagtt tattactgtc agcaggatca taacttacct cccacagtga
661 ttcaacatga aacaaaaacc tcaacaagac catcagtgtt tactagattt taccag
//