GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMIGKLC1 797 bp ds-DNA PRI 27-MAY-1991 DEFINITION Human germline fragment for immunoglobulin kappa light chain (subgroup III variable region gene V(g) ACCESSION X01668 KEYWORDS immunoglobulin; immunoglobulin light chain; kappa-immunoglobulin; variable region. SOURCE Homo sapiens DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 797) AUTHORS Pech,M. and Zachau,H.G. TITLE Immunoglobulin genes of different subgroups are interdigitated within the VK locus JOURNAL Nucleic Acids Res. 12, 9229-9236 (1984) STANDARD full automatic COMMENT From EMBL entry HSIGKLC1; dated 07-NOV-1985. FEATURES Location/Qualifiers misc_feature 2..16 /note="pentekaideca nucleotide box (pd)" misc_feature 31..40 /note="deca nucleotide box (dc)" promoter 73..80 /note="pot. TATA-box" CDS 134..182 /note="pot. signal peptide (aa -20 to -5) (182 is 1st base in codon)" /codon_start=134 intron 183..351 /note="pot. intron" misc_feature 199..200 /note="pot. alternative donor splice site" CDS 352..362 /note="pot. signal peptide (aa -4 to -1) (352 is 2nd base in codon) (362 is 2nd base in codon)" /codon_start=352 CDS 363..431 /note="pot. framework 1, FR1" /codon_start=363 CDS 432..464 /note="pot. complentarity determining region 1, CDR1" /codon_start=432 CDS 465..509 /note="pot. FR2" /codon_start=465 CDS 510..530 /note="pot. CDR2" /codon_start=510 CDS 531..626 /note="pot. FR3" /codon_start=531 CDS 627..647 /note="pot. CDR3" /codon_start=627 misc_feature 650..656 /note="hepta nucleotide box" misc_feature 669..677 /note="nona nucleotide box" BASE COUNT 196 a 223 c 174 g 204 t ORIGIN 1 ctgcagctgg aagctcagct cccacccagc tgctttgcat gtccctccca gctgccctac 61 cttccagagc ccatatcaat gcctgtgtca gagccctggg gaggaactgc tcagttagga 121 cccagaggga accatggaag ccccagctca gcttctcttc ctcctgctac tctggctccc 181 aggtgagggg aacatgaggt ggttttgcac attagtgaaa actcttgcca cctctgctca 241 gcaagaaata taattaaaat tcaaagtata tcaacaattt tggctctact caaagacagt 301 tggtttgatc ttgattacat gagtgcattt ctgttttatt tccaatttca gataccaccg 361 gagaaattgt gttgacacag tctccagcca ccctgtcttt gtctccaggg gaaagagcca 421 ccctctcctg cagggccagt cagagtgtta gcagctactt agcctggtac caacagaaac 481 ctggccaggc tcccaggctc ctcatctatg atgcatccaa cagggccact ggcatcccag 541 ccaggttcag tggcagtggg tctgggacag acttcactct caccatcagc agcctagagc 601 ctgaagattt tgcagtttat tactgtcagc agcgtagcaa ctggcctccc acagtgattc 661 cacatgaaac aaaaacccca acaagaccat cagtgtttac tagattatta taccagctgc 721 ttcctttaca gacagctagt ggggtggcca ctcagtgtta gcatctcagc tctatttggc 781 cattttggag ttcaagt //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS HUMIGKLC2 716 bp ds-DNA PRI 27-MAY-1991 DEFINITION Human germline fragment for immunoglobulin kappa light chain (subgroup III) variable region gene V(h) ACCESSION X02725 KEYWORDS immunoglobulin; immunoglobulin light chain; kappa-immunoglobulin; variable region. SOURCE Homo sapiens DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 716) AUTHORS Pech,M. and Zachau,H.G. TITLE Immunoglobulin genes of different subgroups are interdigitated within the VK locus JOURNAL Nucleic Acids Res. 12, 9229-9236 (1984) STANDARD full automatic COMMENT From EMBL entry HSIGKLC2; dated 07-NOV-1985. FEATURES Location/Qualifiers misc_feature 2..16 /note="pentekaideca nucleotide box (pd)" misc_feature 31..40 /note="deca nucleotide box (dc)" promoter 73..80 /note="pot. TATA-box" CDS 134..182 /note="pot. signal peptide (aa -20 to -5) (182 is 1st base in codon)" /codon_start=134 intron 183..351 /note="pot. intron" misc_feature 199..200 /note="pot. alternative donor splice site" misc_feature 350..351 /note="pot. acceptor splice site violating GTAG rule" CDS 352..362 /note="pot. signal peptide (aa -4 to -1) (352 is 2nd base in codon)" /codon_start=352 CDS 363..431 /note="pot. framework 1 FR1" /codon_start=363 CDS 432..467 /note="pot. complementarity determining region CDR1" /codon_start=432 CDS 468..512 /note="pot. FR2" /codon_start=468 CDS 513..533 /note="pot. CDR2" /codon_start=513 CDS 534..629 /note="pot. FR3" /codon_start=534 CDS 630..650 /note="pot. CDR3" /codon_start=630 misc_feature 653..659 /note="heptanucleotide box" misc_feature 672..680 /note="nonanucleotide box" BASE COUNT 184 a 207 c 151 g 174 t ORIGIN 1 ctgcagctgg aagctcagct cccacccagc tgctttgcat gtccctccca gctgccctac 61 cttccagagc ccatatcaat gcctgggtca gagccctggg aaggaactgc tcagttagga 121 cccagacgga accatggaag ccccagctca gcttctcttc ctcctgctac tctggctccc 181 aggtgagggg aacatgaggt ggttttgcac atcagtgaaa actcctgcca cctctgctca 241 gcaagaaata taattaaaat tcaatgtaga tcaacaattt tggctctact caaagacagc 301 tggtttgatc tagattacat gagtgcattt ctgttttatt tccaatcttg gataccacca 361 gagaaattgt aatgacacag tctccaccca ccctgtcttt gtctccaggg gaaagagtca 421 ccctctcctg cagggccagt cagagtgtta gcagcagcta cttaacctgg tatcagcaga 481 aacctggcca ggcgcccagg ctcctcatct atggtgcatc caccagggcc actagcatcc 541 cagccaggtt cagtggcagt gggtctggga cagacttcac tctcaccatc agcagcctgc 601 agcctgaaga ttttgcagtt tattactgtc agcaggatca taacttacct cccacagtga 661 ttcaacatga aacaaaaacc tcaacaagac catcagtgtt tactagattt taccag //