GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS RATHSDI 1947 bp ds-DNA ROD 27-MAY-1991
DEFINITION Rat 3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-ene-isomerase mRNA, complete cds.
ACCESSION M67465
KEYWORDS 3-beta-hydroxysteroid dehydrogenase; delta-5-delta-4-ene-isomerase.
SOURCE Rat male liver, cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1947)
AUTHORS Zhao,H.F., Rheaume,E., Trudel,C., Coueet,J., Labrie,F. and
Simard,J.
TITLE Structure and sexual dimorphic expression of a liver-specific rat
3-beta-hydroxysteroid dehydrogenase/isomerase
JOURNAL Endocrinology 127, 3237-3239 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 85..1206
/EC_number="1.1.1.145"
/EC_number="5.3.3.1"
/note="3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-ene-isomerase catalyse
delta-5-ene, 3-beta-hydroxy-precursors to delta-4-3-keto
steroids"
/product="3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-ene-isomerase"
/gene="3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-ene-isomerase"
/codon_start=85
polyA_signal 1928..1933
/gene="3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-ene-isomerase"
polyA_site 1947..1947
/gene="3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-ene-isomerase"
BASE COUNT 568 a 461 c 484 g 434 t
ORIGIN
1 tgccttcagg gtctccaacc cttggaaaca aaacgaccac cacacatcta ctgttctctc
61 aactatctgc ttcctgtgtt gaccatgcct gggtggagct gcctggtgac aggagcagga
121 ggatttctgg gccagaggat tgtccaaatg ttggtgcaag agaaagagct gcaggaggtc
181 agagtcctgt ataggacctt cagtccaaaa cacaaagagg aactgtccaa gctgcagaca
241 aaagccaagg tgacggtact gaggggagac attgtggatg cccagttcct gaggagagcg
301 tgccagggca tgtccgtcat catccacacc gctgctgccc ttgatatcgc aggcttcctg
361 cccaggcaga ccatcctaga tgtcaatgtg aaaggtactc agctcctgtt ggatgcttgt
421 gtggaagcca gcgtaccagc cttcatctac agcagctcaa caggtgtggc tggaccaaac
481 tcctacaagg agaccatcct gaacgaccgt gaggaagagc atcgtgaaag cacatggtca
541 aatccatacc catacagcaa aaggatggcc gagaaggcag tgctggcagc caatgggagc
601 atcctgaaaa atggtggcac ttttcataca tgtgccttaa gactcccatt catctatggg
661 gaagaaagcc aaatcatttc aaccatggta aatagagcac tcaagaacaa cagcataatt
721 aaaagacatg ccacattctc catagccaac ccagtgtatg tgggtaatgc agcctgggca
781 cacattctgg ctgccagggg ccttcgagac cccgagaagt cacaaagcat ccaaggacag
841 ttctactaca tctcagatga cacccctcac caaagctatg atgatttaaa ttataccctg
901 agcaaagaat ggggcttctg ccttgattcc agttggagcc ttcctctgcc cctgctctac
961 tggcttgcct tcctgctgga aactgtgagc ttcctgctgc gtccatttta caactatagg
1021 ccacccttta accgcttcat ggtcacgatc ttaaatagcg tgtttaccat ttcctacaag
1081 aaagctcaga gagatctggg ctatgagcca cttgtcagct gggaggaagc caagcaaaaa
1141 acctcggagt ggatcgggac actagtggag caacacaggg agacactgga cacaaagtct
1201 caatgatggg aagagggcag ggacatggcc ccgggtgtta ccccgtcctc cagccaggaa
1261 ctcagaaata atccaactct tacagtttta ttttatacac tctccaactg gtcttcaggt
1321 caccagaaac cttaagagtc actggcccag tcacctgaac aaggtgcagg ggacatcatg
1381 tagaaggaat aaaactgcct gcctcttgtg acacctgggt gttcattcac ctgccatgtg
1441 gtatcacaaa cagaagtagg atctcagctg gcatcaaaac ttcttctttc ttacttaccc
1501 catattaagt aatgtttata ggaagtaatg tttgtaggtg gggcttgagc tcccacacta
1561 gagtcaggag gcaaaaccat gctgaagttc tatatagcaa accaaacctg agagtacttt
1621 cctgatcact acaatagcaa gagagcaaga gcgagagtga gagcaagagc gagagaggga
1681 gggaggaagg gaggaaaggg gatggaggga gggaggaagg gaaggagaga gagagagaga
1741 gagagagaga gagcatcacc atttcacata gggtgtgaac agagtaggaa atcactttgt
1801 ttctcattta ccaagagacc atctgaaaga atctgccttt ctttgcccct gtcataccaa
1861 gaaaccttat tttcgcttat tggacaatgt tctatggtat aaaaaataag agttgtctgg
1921 ttctgggaat aaaactaaat tccaagg
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