GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MACHSDI 1612 bp ss-mRNA PRI 27-MAY-1991
DEFINITION Macaca fuscata 3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase mRNA, complete cds.
ACCESSION M67467
KEYWORDS 3-beta-hydroxy-5-ene steroid dehydrogenase;
delta-5-delta-4 isomerase.
SOURCE Macaca fuscata ovary, cDNA to mRNA.
ORGANISM Macaca fuscata
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini;
Cercopithecidae; Cercopithecinae.
REFERENCE 1 (bases 1 to 1612)
AUTHORS Simard,J., Melner,M.H., Breton,N., Low,K.G. and Labrie,F.
TITLE Characterization of macaque 3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase: Structure and expression
in steroidogenic and peripheral tissues
JOURNAL Mol. Cell. Endocrinol. 75, 101-110 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 69..1190
/EC_number="1.1.1.145"
/EC_number="5.3.3.1"
/note="3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase catalyses
delta-5-ene, 3-beta-hydroxy-precursors to delta-4-3-keto
steroids such as: pregnenolone to progesterone,
dehydroepiandros"
/product="3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase"
/gene="3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase"
/codon_start=69
polyA_signal 1587..1592
/gene="3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase"
polyA_site 1612..1612
/gene="3-beta-hydroxy-5-ene steroid
dehydrogenase/delta-5-delta-4 isomerase"
BASE COUNT 406 a 409 c 388 g 409 t
ORIGIN
1 taagttagat ctgctcccca agcatcttct gtttcctggc gagtgattcc tgctaccttg
61 gattggccat gacgggctgg agctgccttg tgacaggagc aggagggttt ctgggtcaga
121 ggatcgtccg cctcttggtg gaggagaagg agctgaagga gatcagggtc ttggacaagg
181 ccttcagacc agaactgagg gaggaatttt ccaagctcca gaataagacc aagctgactg
241 tactggaagg agacattctg gatgagccat tcctgaagag agcctgccag gacgtctcgg
301 tcgtcatcca caccgcctgt atcattgatg tctttggtgt cactcacaga gagtccatca
361 tgaacgtcaa tgtgaaaggt acccagctcc tgttggaggc ctgtgtccaa gccagtgtgc
421 cagtcttcat ctacaccagt accctagagg tagccgggcc caactcctac aaggaaatca
481 tccagaatgg ccatgaagaa gagcctctgg agaacacatg gcctgctcca tacccataca
541 gcaaaaagct tgctgagaag gctgtgctgg cagccaatgg gtggactctg aaaaatggtg
601 gcaccttgta cacttgtgcc ttaagaccca tgtatatcta tggggaagga ggcccattcc
661 tttctgccag tataaatgag gccctgaaca acaatgggat cctgtcaagt gttggcaagt
721 tctccactgt caacccagtc tatgttggca acgtggcctg ggctcacatt ctggccttga
781 gggccctgcg ggaccccaag aaggccccaa gtgtccaagg acagttctat tacatctcag
841 atgacacacc tcaccaaagc tatgataacc ttaattacat cctgagcaaa gagtttggcc
901 tctgccttga ttccagatgg agccttcctt tagccctgat gtactggatt ggcttcctgc
961 tggaagtagt gagcttccta ctcagcccag tttactccta tcaaccgccc ttcaaccgcc
1021 acacggtgac attgtcaaat agcgtgttca ccttctctta taagaaggct cagcgagatc
1081 tggcgtataa gccgctctac agctgggagg aagccaagca gaaaactgtg gagtgggttg
1141 gttcccttgt ggaccggcac aaggagaccc tgaagtccaa gactcagtga tttaaggatg
1201 acagagatgt gcatgtgggt gttgatagga gatgtcatca agctccaccc tcctggcttc
1261 atacagaagg tgacaaggca caagcccagg tcctgctgcc tccctttcac acaatgccca
1321 acttattgtc ttcttcatgt catcaaaatc tgcacagtca ctggcccaac cagaagcttt
1381 ctgtcctaat catacgccag aggacagaca atatgatttg ctgttaccca atctcagtgg
1441 ctgattctga atgactgtgg tcacttttaa cttgaggttc tcttttgact aatggagcta
1501 attgagctcc atttcccctc ttaaatgaga aagcatttct tttctcttta atctcctatt
1561 acttcacaca gttcaatgta aagagcaata aatgttttaa tgcttaacct gg
//