GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS TATLFC2 1906 bp ss-mRNA INV 27-MAY-1991
DEFINITION Horseshoe crab limulus factor C alternate mRNA, complete cds.
ACCESSION D90272
KEYWORDS alternative splicing; complement; endotoxin;
epidermal growth factor; lectin; limulus factor C.
SOURCE Horseshoe crab adult hemocytes amebocyte, cDNA to mRNA, clone
lambda FC 42.
ORGANISM Tachypleus tridentatus
Eukaryota; Animalia; Metazoa; Arthropoda; Chelicerata; Merostomata;
Xiphosura; Xiphosurida; Limulidae.
REFERENCE 1 (bases 1 to 1906)
AUTHORS Muta,T., Miyata,T., Misumi,Y., Tokunaga,F., Nakamura,T., Toh,Y.,
Ikehara,Y. and Iwanaga,S.
TITLE Limulus factor C: An endotoxin-sensitive serine protease zymogen
with a mosaic structure of complement-like, epidermal growth
factor-like, and lectin-like domains
JOURNAL J. Biol. Chem. 266, 6554-6561 (1991)
STANDARD full staff_review
COMMENT These data kindly submitted in computer readable form by:
Tatsushi Muta
Department of Molecular Biology
Graduate School of Medical Science
Kyushu University
33 Higashi-ku
Fukuoka 812
Japan
Phone: 092-641-1101 x4447
Fax: 092-632-2741
FEATURES Location/Qualifiers
CDS 56..1552
/note="limulus factor C precursor"
sig_peptide 56..130
/note="limulus factor C signal peptide"
mat_peptide 131..1549
/note="limulus factor C"
misc_feature 359..463
/note="EGF-like domain"
misc_feature 479..640
/note="sushi domain (=SCR)"
misc_feature 650..817
/note="sushi domain (=SCR)"
misc_feature 833..1018
/note="sushi domain (=SCR)"
misc_feature 1361..1549
/note="lectin-like domain"
misc_feature 1526..1527
/note="alternative splicing site"
misc_feature 1535..1537
/note="put. glycosylation site"
misc_signal 1885..1890
/note="polyadenylation signal"
misc_feature 1906..1906
/note="polyadenylation site"
BASE COUNT 528 a 356 c 453 g 569 t
ORIGIN
1 gtaagtatca tcaggtttaa cgcgaacgtg gaagaactct gaaggtaact taagtatggt
61 cttagcgtcg tttttggtgt ctggtttagt tctagggata ctagcccaac aaatgcgtcc
121 agttcagtcc agaggagtag atctgggctt gtgtgatgaa acgaggttcg agtgtaagtg
181 tggagatcca ggctatgtgt tcaacgtccc tatgaaacaa tgcacgtact tctatcgatg
241 gaggccttat tgtaaaccat gtgatgacct ggaggctaag gacatttgtc caaagtacaa
301 acgatgtcaa gagtgtaagg ctggtcttga tagttgtgtt acttgtccac ctaacaaata
361 tggtacttgg tgtagcggtg aatgtcaatg taagaatgga ggtatctgtg accagaggac
421 aggagcttgt acctgtcgtg acagatatga aggagcgcac tgtgaaattc tcaaaggttg
481 tcctcttctt ccatcggatt ctcaagttca ggaagtcaga aacccaccag ataatcccca
541 aactattgac tacagctgtt caccagggtt caagcttaaa ggcgtggcac gaattagctg
601 tctcccaaat ggacagtgga gtagctttcc acccaaatgt attcgagaat gtgccaaggt
661 ttcatctcca gaacacggga aagtgaatgc tcctagtggc aatatgatag aaggggctac
721 tttacggttc tcatgtgata gtccctacta cttgattggt caagaaacat taacctgcca
781 gggtaatggt cagtggagtg gacaaatacc acaatgtaag aagttggtct tctgtcctga
841 ccttgatcct gtaaaccatg ctgaacacca ggttaaaatt ggtgtggaac aaaaatatgg
901 tcagtttcct caaggcactg aagtgaccta tacgtgttcg ggtaactact tcttgatggg
961 ttttaacacc ttaaaatgta accctgatgg gtcctggtca ggatcacagc catcctgtgt
1021 taaagtggca gacagagagg tcgactgtga cagtaaagct gtagacttct tggatgatgt
1081 tggtgaacct gtcaggatcc actgtcctgc tggctgttct ttgacagctg gtactgtgtg
1141 gggtacagcc atataccacg aactttcctc agtgtgtcgt gcagccatcc atgctggcaa
1201 gcttccaaac tctggagggg cggtgcatgt agtgaacaat ggcccctact cggactttct
1261 gggtagtgac ctgaatggga taaaatcgga agagttgaag tctcttgccc gcagttttcg
1321 atttgattat gtcagttcat ccacagcagg tagatcagga tgtcctgatg gatggtttga
1381 ggtagaagag aactgtgtgt acgttacatc aaaacagaga gcctgggaaa gagctcaagg
1441 tgtgtgtacc aatatggctg ctcgtcttgc tgtgctagac aaagatctaa ttccgagttc
1501 cttgactgag actctacgag ggaaaggtac tgataatgtt actgcaacct aagtagactt
1561 tattttagtc taagatatct tgtgtcaatt gttgacttgc tactcttact ttattgtaat
1621 aaaactgtta taaagtatta agtcttgttt attttattac tgtttaaagt atactacaag
1681 ggttacacct aaaaggaaat ttctatctga caatttcata aaaagtggat gttacttttg
1741 attttcgttg gttgttaaat gcacatccgg tttgtaaaca tctaagttcc cacaaacagg
1801 ctctgtggtc ttgtaaaaat ctaaactaat accactttta atatgtttta aacctttttt
1861 ttatgtatgc ttatcagaga ctaaaataaa ggtttttaat aactgt
//