GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS ECOTRPX 7017 bp ds-DNA BCT 27-MAY-1991
DEFINITION E. coli trp operon with the genes trpE, trpD, trpC, trpB and trpA.
Genetic map position approximately 27.5 minutes. These genes code
for the following enzymes: trpE - anthranilate synthetase [E.C.
4.1.3.27] trpD - glutamine amidotransferase-phophorib
ACCESSION V00372
KEYWORDS isomerase; synthetase; transferase.
SOURCE Escherichia coli DNA.
ORGANISM Escherichia coli
Prokaryota; Bacteria; Gracilicutes; Scotobacteria;
Facultatively anaerobic rods; Enterobacteriaceae.
REFERENCE 1 (bases 1 to 7017)
AUTHORS Yanofsky,C., Platt,T., Crawford,I.P., Nichols,B.P., Christie,G.E.,
Horowitz,H., van Cleemput,M. and Wu,A.M.
TITLE The complete nucleotide sequence of the tryptophan operon of
Escherichia coli
JOURNAL Nucleic Acids Res. 9, 6647-6668 (1981)
STANDARD full automatic
COMMENT SWISS-PROT; P00895; TRPE$ECOLI. SWISS-PROT; P00904; TRPG$ECOLI.
SWISS-PROT; P00909; TRPC$ECOLI. SWISS-PROT; P00928; TRPA$ECOLI.
SWISS-PROT; P00932; TRPB$ECOLI.
See also the entries <ECTRPD>, <ECTRPC>, <ECTRPB>, and <ECTRPA> for
sequences of the individual genes (with slight differences).
From EMBL entry ECTRPX; dated 06-JUL-1989.
FEATURES Location/Qualifiers
mRNA 1..6991
/note="alternate mRNA"
mRNA 1..6720
/note="messenger RNA"
CDS 163..1722
/note="trpE"
/codon_start=163
CDS 1725..3317
/note="trpD"
/codon_start=1725
CDS 3324..4673
/note="trpC"
/codon_start=3324
CDS 4688..5878
/note="trpB"
/codon_start=4688
CDS 5881..6684
/note="trpA"
/codon_start=5881
BASE COUNT 1639 a 1861 c 1884 g 1633 t
ORIGIN
1 aagttcacgt aaaaagggta tcgacaatga aagcaatttt cgtactgaaa ggttggtggc
61 gcacttcctg aaacgggcag tgtattcacc atgcgtaaag caatcagata cccagcccgc
121 ctaatgagcg ggcttttttt tgaacaaaat tagagaataa caatgcaaac acaaaaaccg
181 actctcgaac tgctaacctg cgaaggcgct tatcgcgaca atcccaccgc gctttttcac
241 cagttgtgtg gggatcgtcc ggcaacgctg ctgctggaat ccgcagatat cgacagcaaa
301 gatgatttaa aaagcctgct gctggtagac agtgcgctgc gcattacagc tttaggtgac
361 actgtcacaa tccaggcact ttccggcaac ggcgaagccc tcctggcact actggataac
421 gccctgcctg cgggtgtgga aagtgaacaa tcaccaaact gccgtgtgct gcgcttcccc
481 cctgtcagtc cactgctgga tgaagacgcc cgcttatgct ccctttcggt ttttgacgct
541 ttccgtttat tgcagaatct gttgaatgta ccgaaggaag aacgagaagc catgttcttc
601 agcggcctgt tctcttatga ccttgtggcg ggatttgaag atttaccgca actgtcagcg
661 gaaaataact gccctgattt ctgtttttat ctcgctgaaa cgctgatggt gattgaccat
721 cagaaaaaaa gcacccgtat tcaggccagc ctgtttgctc cgaatgaaga agaaaaacaa
781 cgtctcactg ctcgcctgaa cgaactacgt cagcaactga ccgaagccgc gccgccgctg
841 ccagtggttt ccgtgccgca tatgcgttgt gaatgtaatc agagcgatga agagttcggt
901 ggcgtagtgc gtttgttgca aaaagcgatt cgcgctggag aaattttcca ggtggtgcca
961 tctcgccgtt tctctctgcc ctgcccgtca ccgctggcgg cctattacgt gctgaaaaag
1021 agtaatccca gcccgtacat gttttttatg caggataatg atttcaccct atttggcgcg
1081 tcgccggaaa gctcgctcaa gtatgatgcc accagccgcc agattgagat ctacccgatt
1141 gccggaacac gcccacgcgg tcgtcgcgcc gatggttcac tggacagaga tctcgacagc
1201 cgtattgaac tggaaatgcg taccgatcat aaagagctgt ctgaacatct gatgctggtt
1261 gatctcgccc gtaatgatct ggcacgcatt tgcacccccg gcagccgcta cgtcgccgat
1321 ctcaccaaag ttgaccgtta ttcctatgtg atgcacctcg tctctcgcgt agtcggcgaa
1381 ctgcgtcacg atcttgacgc cctgcacgct tatcgcgcct gtatgaatat ggggacgtta
1441 agcggtgcgc cgaaagtacg cgctatgcag ttaattgccg aggcggaagg tcgtcgccgc
1501 ggcagctacg gcggcgcggt aggttatttc accgcgcatg gcgatctcga cacctgcatt
1561 gtgatccgct cggcgctggt ggaaaacggt atcgccaccg tgcaagcggg tgctggtgta
1621 gtccttgatt ctgttccgca gtcggaagcc gacgaaaccc gtaacaaagc ccgcgctgta
1681 ctgcgcgcta ttgccaccgc gcatcatgca caggagactt tctgatggct gacattctgc
1741 tgctcgataa tatcgactct tttacgtaca acctggcaga tcagttgcgc agcaatgggc
1801 ataacgtggt gatttaccgc aaccatatac cggcgcaaac cttaattgaa cgcttggcga
1861 ccatgagtaa tccggtgctg atgctttctc ctggccccgg tgtgccgagc gaagccggtt
1921 gtatgccgga actcctcacc cgcttgcgtg gcaagctgcc cattattggc atttgcctcg
1981 gacatcaggc gattgtcgaa gcttacgggg gctatgtcgg tcaggcgggc gaaattctcc
2041 acggtaaagc ctccagcatt gaacatgacg gtcaggcgat gtttgccgga ttaacaaacc
2101 cgctgccggt ggcgcgttat cactcgctgg ttggcagtaa cattccggcc ggtttaacca
2161 tcaacgccca ttttaatggc atggtgatgg cagtacgtca cgatgcggat cgcgtttgtg
2221 gattccagtt ccatccggaa tccattctca ccacccaggg cgctcgcctg ctggaacaaa
2281 cgctggcctg ggcgcagcat aaactagagc cagccaacac gctgcaaccg attctggaaa
2341 aactgtatca ggcgcagacg cttagccaac aagaaagcca ccagctgttt tcagcggtgg
2401 tgcgtggcga gctgaagccg gaacaactgg cggcggcgct ggtgagcatg aaaattcgcg
2461 gtgagcaccc gaacgagatc gccggggcag caaccgcgct actggaaaac gcagcgccgt
2521 tcccgcgccc ggattatctg tttgctgata tcgtcggtac tggcggtgac ggcagcaaca
2581 gtatcaatat ttctaccgcc agtgcgtttg tcgccgcggc ctgtgggctg aaagtggcga
2641 aacacggcaa ccgtagcgtc tccagtaaat ctggttcgtc cgatctgctg gcggcgttcg
2701 gtattaatct tgatatgaac gccgataaat cgcgccaggc gctggatgag ttaggtgtat
2761 gtttcctctt tgcgccgaag tatcacaccg gattccgcca cgcgatgccg gttcgccagc
2821 aactgaaaac ccgcaccctg ttcaatgtgc tggggccatt gattaacccg gcgcatccgc
2881 cgctggcgtt aattggtgtt tatagtccgg aactggtgct gccgattgcc gaaaccttgc
2941 gcgtgctggg gtatcaacgc gcggcggtgg tgcacagcgg cgggatggat gaagtttcat
3001 tacacgcgcc gacaatcgtt gccgaactgc atgacggcga aattaaaagc tatcagctca
3061 ccgcagaaga ctttggcctg acaccctacc accaggagca actggcaggc ggaacaccgg
3121 aagaaaaccg tgacatttta acacgtttgt tacaaggtaa aggcgacgcc gcccatgaag
3181 cagccgtcgc tgcgaacgtc gccatgttaa tgcgcctgca tggccatgaa gatctgcaag
3241 ccaatgcgca aaccgttctt gaggtactgc gcagtggttc cgcttacgac agagtcaccg
3301 cactggcggc acgagggtaa atgatgcaaa ccgttttagc gaaaatcgtc gcagacaagg
3361 cgatttgggt agaagcccgc aaacagcagc aaccgctggc cagttttcag gaggttcagc
3421 cgagcacgcg acatttttat gatgcgctac agggtgcgcg cacggcgttt attctggagt
3481 gcaagaaagc gtcgccgtca aaaggcgtga tccgtgatga tttcgatcca gcacgcattg
3541 ccgccattta taaacattac gcttcggcaa tttcggtgct gactgatgag aaatatttca
3601 ggggtagctt taatttcctc cccatcgtca gccaaatcgc cccgcagccg attttatgta
3661 aagacttcat tatcgaccct taccagatct atctggcgcg ctattaccag gccgatgcct
3721 gcttattaat gctttcagta ctggatgacg accaatatcg ccagcttgcc gccgtcgctc
3781 acagtctgga gatgggggtg ctgaccgaag tcagtaatga agaggaacag gagcgcgcca
3841 ttgcattggg agcaaaggtc gttggcatca acaaccgcga tctgcgtgat ttgtcgattg
3901 atctcaaccg tacccgcgag cttgcgccga aactggggca caacgtgacg gtaatcagcg
3961 aatccggcat caatacttac gctcaggtgc gcgagttaag ccacttcgct aacggttttc
4021 tgattggttc ggcgttgatg gcccatgacg atttgcacgc cgccgtgcgc cgggtgttgc
4081 tgggtgagaa taaagtatgt ggcctgacgc gtgggcaaga tgctaaagca gcttatgacg
4141 cgggcgcgat ttacggtggg ttgatttttg cgacatcacc gcgttgcgtc aacgatgaac
4201 aggcgcagga agtgatggct gcggcaccgt tgcagtatgt tggcgtgttc cgcaatcacg
4261 atattgccga tgtggtggac aaagctaagg tgttatcgct ggtggcagtg caactgcatg
4321 gtaatgaaga acagctgtat atcgatacgc tgcgtgaagc tctgccagca catgttgcca
4381 tctggaaagc attaagcgtc ggtgaaaccc tgcccgcccg cgagtttcag cacgttgata
4441 aatatgtttt agacaacggc cagggtggaa gcgggcaacg ttttgactgg tcactattaa
4501 atggtcaaac gcttggcaac gttctgctgg cggggggctt aggcgcagat aactgcgtgg
4561 aagcggcaca aaccggctgc gccggacttg attttaattc tgctgtagag tcgcaaccgg
4621 gcatcaaaga cgcacgtctt ttggcctcgg ttttccagac gctgcgcgca tattaaggaa
4681 aggaacaatg acaacattac ttaaccccta ttttggtgag tttggcggca tgtacgtgcc
4741 acaaatcctg atgcctgctc tgcgccagct ggaagaagct tttgtcagtg cgcaaaaaga
4801 tcctgaattt caggctcagt tcaacgacct gctgaaaaac tatgccgggc gtccaaccgc
4861 gctgaccaaa tgccagaaca ttacagccgg gacgaacacc acgctgtatc tcaagcgtga
4921 agatttgctg cacggcggcg cgcataaaac taaccaggtg ctggggcagg cgttgctggc
4981 gaagcggatg ggtaaaaccg aaatcatcgc cgaaaccggt gccggtcagc atggcgtggc
5041 gtcggccctg gccagcgccc tgctcggcct gaaatgccgt atttatatgg gtgccaaaga
5101 cgttgaacgc cagtcgccta acgtttttcg tatgcgctta atgggtgcgg aagtgatccc
5161 ggtgcatagc ggttccgcga cgctgaaaga tgcctgtaac gaggcgctgc gcgactggtc
5221 cggtagttac gaaaccgcgc actatatgct gggcaccgca gctggcccgc atccttatcc
5281 gaccattgtg cgtgagtttc agcggatgat tggcgaagaa accaaagcgc agattctgga
5341 aagagaaggt cgcctgccgg atgccgttat cgcctgtgtt ggcggcggtt cgaatgccat
5401 cggcatgttt gctgatttca tcaatgaaac caacgtcggc ctgattggtg tggagccagg
5461 tggtcacggt atcgaaactg gcgagcacgg cgcaccgcta aaacatggtc gcgtgggtat
5521 ctatttcggt atgaaagcgc cgatgatgca aaccgaagac gggcagattg aagaatctta
5581 ctccatctcc gccggactgg atttcccgtc tgtcggccca caacacgcgt atcttaacag
5641 cactggacgc gctgattacg tgtctattac cgatgatgaa gcccttgaag ccttcaaaac
5701 gctgtgcctg cacgaaggga tcatcccggc gctggaatcc tcccacgcct tggcccatgc
5761 gttgaaaatg atgcgcgaaa acccggataa agagcagcta ctggtggtta acctttccgg
5821 tcgcggcgat aaagacatct tcaccgttca cgatattttg aaagcacgag gggaaatctg
5881 atggaacgct acgaatctct gtttgcccag ttgaaggagc gcaaagaagg cgcattcgtt
5941 cctttcgtca cgctcggtga tccgggcatt gagcagtcat tgaaaattat cgatacgcta
6001 attgaagccg gtgctgacgc gctggagtta ggtatcccct tctccgaccc actggcggat
6061 ggcccgacga ttcaaaacgc cactctgcgc gcctttgcgg caggtgtgac tccggcacaa
6121 tgttttgaaa tgctggcact gattcgccag aaacacccga ccattcccat tggcctgttg
6181 atgtatgcca atctggtgtt taacaaaggc attgatgagt tttatgccca gtgcgaaaaa
6241 gtcggcgtcg attcggtgct ggttgccgat gtgccagttg aagagtccgc gcccttccgc
6301 caggccgcgt tgcgtcacaa cgtcgcacct atcttcatct gcccgccaaa tgccgatgac
6361 gacctgctgc gccagatagc ctcttacggt cgtggttaca cctatttgct gtcacgagca
6421 ggcgtgaccg gcgcagaaaa ccgcgccgcg ttacccctca atcatctggt tgcgaagctg
6481 aaagagtaca acgctgcacc tccattgcag ggatttggta tttccgcccc ggatcaggta
6541 aaagcagcga ttgatgcagg agctgcgggc gcgatttctg gttcggccat tgttaaaatc
6601 atcgagcaac atattaatga gccagagaaa atgctggcgg cactgaaagt ttttgtacaa
6661 ccgatgaaag cggcgacgcg cagttaatcc cacagccgcc agttccgctg gcggcatttt
6721 aactttcttt aatgaagccg gaaaaatcct aaattcattt aatatttatc tttttaccgt
6781 ttcgcttacc ccggtcgaac gtcaacttac gtcatttttc cgcccaacag taatataaac
6841 aaacaaatta aacccgcaac ataacaccag taaaatcaat attttctcta agtcacttat
6901 tcctcaggtc cttgttaata tatccagaat gttcctcaaa atatattttc cctctatctt
6961 ctcgttgcgc ttaatttcac taattctcat tagcgactaa ttttaatgag tgtcgac
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