GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSCFOS 3967 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse c-fos oncogene
ACCESSION V00727
KEYWORDS cellular oncogene; fos cellular oncogene.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 420 to 3967)
AUTHORS Van Beveren,C., van Straaten,F., Curran,T., Mueller,R. and
Verma,I.M.
TITLE Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that
viral and cellular fos gene products have different carboxy termini
JOURNAL Cell 32, 1241-1255 (1983)
STANDARD full automatic
REFERENCE 2 (bases 1 to 419)
AUTHORS Renz,M., Neuberg,M., Kurz,C., Bravo,R. and Mueller,R.
TITLE Regulation of c-fos transcription in mouse fibroblasts:
identification of DNase I-hypersensitive sites and regulatory
upstream sequences
JOURNAL EMBO J. 4, 3711-3716 (1985)
STANDARD full automatic
COMMENT EPD; 11144; Mm c-fos. SWISS-PROT; P01101; FOS$MOUSE.
From EMBL entry MMCFOS; dated 03-JAN-1991.
FEATURES Location/Qualifiers
CDS join(703..843,1598..1849,2255..2362,2480..3118)
/gene="c-fos"
/codon_start=703
precursor_RNA 551..>3967
/note="primary transcript"
mRNA 551..843
/note="exon 1"
intron 844..1597
/note="intron I"
mRNA 1598..1849
mRNA 1598..1849
/note="exon 2"
intron 1850..2254
/note="intron II"
mRNA 2255..2362
mRNA 2255..2362
/note="exon 3"
intron 2363..2479
/note="intron III"
mRNA 2480..>3967
/note="exon 4"
misc_feature 3912..3917
/note="polyA addition signal"
BASE COUNT 882 a 1095 c 1040 g 950 t
ORIGIN
1 ataccagaga ctcaaaaaaa aaaaaaaagt tccagattgc tggacaatga cccgggtctc
61 atcccttgac cctgggaacc gggtccacat tgaatcaggt gcgaatgttc gctcgccttc
121 tctgcctttc ccgcctcccc tcccccggcc gcggccccgg ttccccccct gcgctgcacc
181 ctcagagttg gctgcagccg gcgagctgtt cccgtcaatc cctccctcct ttacacagga
241 tgtccatatt aggacatctg cgtcagcagg tttccacggc cggtccctgt tgttctgggg
301 gggggaccat ctccgaaatc ctacacgcgg aaggtctagg agacccccta agatcccaaa
361 tgtgaacact cataggtgaa agatgtatgc caagacgggg gttgaaagcc tggggcgtag
421 agttgacgac agagcgcccg cagagggcct tggggcgcgc ttcccccccc ttccagttcc
481 gcccagtgac gtaggaagtc catccattca cagcgcttct ataaaggcgc cagctgaggc
541 gcctactact ccaaccgcga ctgcagcgag caactgagaa gactggatag agccggcggt
601 tccgcgaacg agcagtgacc gcgctcccac ccagctctgc tctgcagctc ccaccagtgt
661 ctacccctgg accccttgcc gggctttccc caaacttcga ccatgatgtt ctcgggtttc
721 aacgccgact acgaggcgtc atcctcccgc tgcagtagcg cctccccggc cggggacagc
781 ctttcctact accattcccc agccgactcc ttctccagca tgggctctcc tgtcaacaca
841 caggtgagtt tggctttgtg tagccgccag gtccgcgctg agggtcgccg tggaggagac
901 actggggtgt gactcgcagg ggcggggggg tcttcctttt tcgctctgga gggagactgg
961 cgcggtcaga gcagccttag cctgggaacc caggacttgt ctgagcgcgt gcacacttgt
1021 catagtaaga cttagtgacc ccttcccgcg cggcaggttt attctgagtg gcctgcctgc
1081 attcttctct cggccgactt gtttctgaga tcagccgggg ccaacaagtc tcgagcaaag
1141 agtcgctaac tagagtttgg gaggcggcaa accgcggcaa tcccccctcc cggggcagcc
1201 tggagcaggg aggagggagg agggaggagg gtgctgcggg cgggtgtgta aggcagtttc
1261 attgataaaa agcgagttca ttctggagac tccggagcag cgcctgcgtc agcgcagacg
1321 tcagggatat ttataacaaa ccccctttcg agcgagtgat gccgaaggga taacgggaac
1381 gcagcagtag gatggaggag aaaggctgcg ctgcggaatt caagggagga tattgggaga
1441 gcttttatct ccgatgaggt gcatacagga agacataagc agtctctgac cggaatgctt
1501 ctctctccct gcttcatgcg acactagggc cacttgctcc acctgtgtct ggaacctcct
1561 cgctcacctc cgctttcctc tttttgtttt gtttcaggac ttttgcgcag atctgtccgt
1621 ctctagtgcc aactttatcc ccacggtgac agccatctcc accagcccag acctgcagtg
1681 gctggtgcag cccactctgg tctcctccgt ggccccatcg cagaccagag cgccccatcc
1741 ttacggactc cccacccagt ctgctggggc ttacgccaga gcgggaatgg tgaagaccgt
1801 gtcaggaggc agagcgcaga gcatcggcag aaggggcaaa gtagagcagg tgagcagcga
1861 ttctggacct ttgtgggctg gggggggggg ggggggcgga gactgacgca cagaccacac
1921 aacagagaag ggacgctact gactgcactt cctgaccagg agctgtggct gctagccctt
1981 tccctccctt gtcagatttt gacagttgga cccaagacaa actctagaca gtttccctga
2041 cagcttccta cttcattctc tagccgggga gcttctttgt tcccctgcta aagatctcac
2101 tttaaatgca aatcacactc tgcctgccaa ctgcaggtta gaaaaactgc ttcaccgaga
2161 ggtgcgggtg ctgtaggagc cagtttcact ggggtgactg aatggaggtg acactagaca
2221 accttaactg aatgttggtc cttttcttct atagctatct cctgaagagg aagagaaacg
2281 gagaatccga agggaacgga ataagatggc tgcagccaag tgccggaatc ggaggaggga
2341 gctgacagat acactccaag cggtaggttg aaccagctgc tgctcctgaa actttattaa
2401 agttggagct tgggactatg ggcgcagggt ccttgagcat gcccgtgtct tatgctttct
2461 tatatctctc cctatgcagg agacagatca acttgaagat gagaagtctg cgttgcagac
2521 tgagattgcc aatctgctga aagagaagga aaaactggag tttattttgg cagcccaccg
2581 acctgcctgc aagatccccg atgaccttgg cttcccagag gagatgtctg tggcctccct
2641 ggatttgact ggaggtctgc ctgaggcttc caccccagag tctgaggagg ccttcaccct
2701 gccccttctc aacgaccctg agcccaagcc atccttggag ccagtcaaga gcatcagcaa
2761 cgtggagctg aaggcagaac cctttgatga cttcttgttt ccggcatcat ctaggcccag
2821 tggctcagag acctcccgct ctgtgccaga tgtggacctg tccggttcct tctatgcagc
2881 agactgggag cctctgcaca gcaattcctt ggggatgggg cccatggtca cagagctgga
2941 gcccctgtgt actcccgtgg tcacctgtac tccgggctgc actacttaca cgtcttcctt
3001 tgtcttcacc taccctgaag ctgactcctt cccaagctgt gccgctgccc accgaaaggg
3061 cagcagcagc aacgagccct cctccgactc cctgagctca cccacgctgc tggccctgtg
3121 agcagtcaga gaaggcaagg cagccggcat ccagacgtgc cactgcccga gctggtgcat
3181 tacagagagg agaaacacgt cttccctcga aggttcccgt cgacctaggg aggaccttac
3241 ctgttcgtga aacacaccag gctgtgggcc tcaaggactt gcaagcatcc acatctggcc
3301 tccagtcctc acctcttcca gagatgtagc aaaaacaaaa caaaacaaaa caaaaaaccg
3361 catggagtgt gttgttccta gtgacacctg agagctggta gttagtagag catgtgagtc
3421 aaggcctggt ctgtgtctct tttctctttc tccttagttt tctcatagca ctaactaatc
3481 tgttgggttc attattggaa ttaacctggt gctggattgt atctagtgca gctgatttta
3541 acaataccta ctgtgttcct ggcaatagcg tgttccaatt agaaacgacc aatattaaac
3601 taagaaaaga taggacttta ttttccagta gatagaaatc aatagctata tccatgtact
3661 gtagtccttc agcgtcaatg ttcattgtca tgttactgat catgcattgt cgaggtggtc
3721 tgaatgttct gacattaaca gttttccatg aaaacgtttt tattgtgttt tcaatttatt
3781 tattaagatg gattctcaga tatttatatt tttattttat ttttttctac cctgaggtct
3841 ttcgacatgt ggaaagtgaa tttgaatgaa aaattttaag cattgtttgc ttattgttcc
3901 aggacattgt caataaaagc atttaagttg aatgcgacca ccttcttgct ctctttattc
3961 tcagttt
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