GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSCY03 6715 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene for cytochrome P3-450
ACCESSION X01682
KEYWORDS cytochrome; cytochrome P-450.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 6715)
AUTHORS Kimura,S., Gonzalez,F.J. and Nebert,D.W.
TITLE The murine Ah locus
JOURNAL J. Biol. Chem. 259, 10705-10713 (1984)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1894)
AUTHORS Kimura,S., Gonzalez,F.J. and Nebert,D.W.
TITLE Mouse cytochrome P3-450: complete cDNA and amino acid sequence
JOURNAL Nucleic Acids Res. 12, 2917-2928 (1984)
STANDARD full automatic
COMMENT *source: strain=C57BL/6N;
From EMBL entry MMCY03; dated 03-JAN-1991.
FEATURES Location/Qualifiers
CDS join(1127..1954,2544..2661,3315..3404,3683..3806,
4579..4665,6130..6421)
/product="cytochrome P3-450"
/codon_start=1127
precursor_RNA 1..6715
/note="primary transcript"
mRNA 1..51
/note="exon 1"
intron 52..1118
/note="intron I"
mRNA 1119..1954
/note="exon 2"
intron 1955..2543
/note="intron II"
mRNA 2544..2661
mRNA 2544..2661
/note="exon 3"
intron 2662..3314
/note="intron III"
mRNA 3315..3404
mRNA 3315..3404
/note="exon 4"
intron 3405..3682
/note="intron IV"
mRNA 3683..3806
mRNA 3683..3806
/note="exon 5"
intron 3807..4578
/note="intron V"
mRNA 4579..4665
mRNA 4579..4665
/note="exon 6"
intron 4666..6129
/note="intron VI"
mRNA 6130..6715
/note="exon 7"
misc_feature 6696..6701
/note="put. polyadenylation signal"
polyA_site 6715..6715
/note="polyadenylation site"
BASE COUNT 1763 a 1698 c 1577 g 1677 t
ORIGIN
1 gtcctggact gactcccaca actctgccag tctccagccc ctgcccttca ggtacgtctg
61 tgtgtctttc cagatcatga gacctgctgc tatttcctaa atgctattat gatggagaaa
121 cggggaccct gtgggaagtg aaggaaatct gagaggtcta aggttttgct tcttaattct
181 cagccctgga cctttgcacc tccgtgtgtg tgtttatatg tatgtgtgtg tgtgtgtgta
241 tctctgtctg tctttctgtc tttctgtctg tctgtctgaa caccacagct tatgtgtgga
301 gctcagagac aactttcagg aatcagttct ttctttccac cacatcaatt ccagggatca
361 aactcaagtc atcaggcttt cagcaagtgc ttttaccact gagccatctc actagcccat
421 tacctttaat taaacagttt caaccaggct ttttctgagg acagttgcct ggagtaaaga
481 ggtagggaaa gaattcccac ctggcattgg acagccccag acctaactgt agcccacttc
541 agcctctaag catggaagta aatgaagact cacttttgga ggaggaatct ctgctgggtg
601 ttgttagagt gttatagaga aaggaggata tcacaggtca ttgatatcat cccaggaaca
661 gtggctttct gtcgcttggg caaggaggca tcttctgttc cttgggtatg tggagggtac
721 caccaatgtg ttggaccctc tggcagaaag tggtacaaac actctgttac tgtggctgtt
781 gaggagctgc ttttagcatc atggttttgg agtggtcact tgcatccatg ccagtctgag
841 aattggaaac gagagaggta gacaaaacag cctgggatgg aaatcaagac actaaagttg
901 taaatgcaag gctccttccc agcccttggc ttttgggatg gggtaagggc aaatccctga
961 aagaacaaga cacaggacag gtatattcac gtttctgatg tgtggctgaa agccaagcac
1021 aggatgtatg tcagcaccta ctgaatgagt gaatgaaagg ataaacggaa ggctcagaat
1081 ccatccccaa ccactccatc tttccatttc ccctgcagtg gtacagatgg cgttctccca
1141 gtacatctcc ttagccccag agctgctact ggccactgcc atcttctgtt tagtgttctg
1201 gatggtcaga gcctcaagga cccaggttcc caaaggcctg aagaatccac ccggaccctg
1261 gggcttgccc ttcattgggc acatgctgac tgtggggaag aacccacacc tgtcactgac
1321 acggctgagt cagcagtatg gggacgtgct gcagatccgc atcggctcca ctcctgtggt
1381 ggtgctgagc ggcctgaaca ccatcaagca ggccctggtg aggcagggag atgacttcaa
1441 gggccgacca gacctctaca gcttcacact tatcactaac ggcaagagca tgactttcaa
1501 cccagactct ggacccgtgt gggctgcccg ccggcgcctg gcccaggatg ccctgaagag
1561 cttctccata gcctcggacc cgacgtcagc atcctcttgc tatttggagg agcacgtgag
1621 caaggaggct aaccatctcg tcagcaagct tcagaaggcg atggcagagg ttggccactt
1681 cgaaccagtc agccaggtgg tggaatcggt ggctaacgtc attggtgcca tgtgctttgg
1741 gaagaacttc ccccggaaga gcgaggagat gctgaacatc gtgaataaca gcaaggactt
1801 tgtggagaat gtcacctcag ggaatgcagt ggacttcttc ccggtcctgc gctacctgcc
1861 caacccggcc ctcaagaggt ttaagacctt caatgataac ttcgtgctgt ttctgcagaa
1921 aactgtccag gagcactacc aagacttcaa caagtgagtc tgggaggcag gctgtaaccc
1981 acatcaccgc cagagaaatg ccctctggag tccttctccc aggtactcag agtgccgtgt
2041 gcagcggaga gtgccgtgtg cagcggagac cttgggaagc tctgggccct tagcaactat
2101 gaccttccct tcttccttac agctcgcctc tggggactgt tccaaacccc aaaagtggag
2161 gcatgtgatg gagccttggc gagctttgca atgggggtgg gggtggggtt cactaagtta
2221 aaggcaattt attgttctgc aggaaaatga accctacaga ggctacgtaa gctccagctt
2281 cgtgtcactt ttcttccctg tgttcaccct acctcttcct cctctgaaac ctgagccctg
2341 gggttatggg aaagaagggt caggggtaca tgaaatgact acactctatt tagggctgat
2401 gctagttcaa aaatctgagc tctagcccag ggcctggaga ccaaggcagt tcccaggccc
2461 ccgggacata tcaaatggga tgggtaaggt tgggcatttg gccctggaag tgccaaagtt
2521 accctgaact tatgtcctcc tagaacagta tccaagacat cacaagtgcc ctgttcaagc
2581 acagcgagaa ctacaaagac aatggcggtc tcatccccga ggagaagatt gtcaacattg
2641 tcaatgacat ctttggagct ggtaggagcc acctttctgc ccctccatcc accaattgct
2701 attcacccat atacaacctc atcaaccaca tcaggtgaca cacaacagac tcctgcccta
2761 agatcaaggt gtgacctcat gctgtgccac caactcctag aagtaactca actaagtccc
2821 tccctttgga ggtctgggtt taccacaggg aaagagtaag agttctataa ctacaagtcc
2881 agacttataa tcccagctgc tgactagaag caagtgtcta ttggggtttt gtttgttttg
2941 gtttctgatt tggttggttt tgacttatta catttgagac taggtttcac ctctaaatcc
3001 caggctggcc tcaaacttac gacagttctc ctgcctctga ctctgtagtg ttgggattct
3061 agatataagc catcatgctc agcttttaag attctgctga ggactcactc agtccttccc
3121 tcagggtaga caggatggga gccagagaga gagagacaga gagacagaga cagagagaga
3181 cagagagaca gagagacaga gacagagaca cttatgctag tgcttgcttg gtaaaaacaa
3241 acaaacaaaa aaacccaaag agttttcctt ctgtccattt tctcttcccc ttcaccctcc
3301 cccctgctgc ccaggctttg acacagtcac cacagccatc acctggagca ttttgctact
3361 tgtgacatgg cctaacgtgc agaggaagat ccatgaggag ctgggtacgt actgttccca
3421 accctagagt cagagaagcc ttgaagctct ggtcacttga cccacaaata cataaataca
3481 tgtttatgtg cccactatga gtaagcccta ggcatatggc atgccccact tatccaaatg
3541 cattgttggg tcggggggga ctgtggggag tctcagaaac gcgagtaaac agtacaacat
3601 agacagagtg atattagtac aacagggacc caagtgcatg cagcagacag aacatcccat
3661 gaggtctgct cgtgctttac agacacggtg gttggcaggg atcggcaacc acggctttct
3721 gaccgtcccc agctgccata tctagaggcc ttcatcctgg agatctaccg atacacatcc
3781 tttgtcccct tcaccatccc ccacaggtaa tgaccctgtt ctgtgcccct caagttttca
3841 tacttccctc tacccaactt cccagctctg gccccaaatc aggatccatc tcattcctga
3901 agtgtgtcct tagctcctga tctcagtttc tggtctaacc catccagtcc agtcccccca
3961 tggccccagc tgtcactcac tcacctccac ttgtatttac tccctatgga catcttcttc
4021 agccaggccc tcctcactgt ccctcacaag ggtaatccag ccacctgcca acttggctta
4081 agcttgacct tctgcccgga aagacttcta accaattatc tgcctcccaa attctactct
4141 agcccaatac cagtcctgac tcgtgtactc ttccatgtga gctcctttgg gctcactaat
4201 cctctgagga tttgtagaac tttcaggccc atgttccctg attgtaagag caaacattta
4261 gctcagctca cactcaagtc tagttgtttc ttatacaaaa ggctgcagat tcttcggggc
4321 aagcccaccc ctgatttctt aggttcagac tgccccagtg cacctctgag cacaaagacg
4381 gtctactaaa caaatgtcca agagcaggat cccaaaaaag gaaaggcaat tgccccatat
4441 tccatgaccc tcacatatct cccagtactg ggtttggaga ccgtgatagt cagacactgg
4501 gatgaagtgg agaaaggaac aagccatatc tcagcttttt caagccctga gctggacata
4561 gctgtcttct ttcctcagca caacgaggga cacctcactg aatggcttcc acattcccaa
4621 ggagcgctgt atctacataa accagtggca ggtcaaccat gatgagtgag tacatagccc
4681 tcagggggaa agggaacact ctgcagtagg aaggttgtcc gtctgtccct tcagaaagtg
4741 cttataaaag gaatgcctca ttgctagata gtctgttcta agtgacaaaa cttagaccct
4801 gtttcacaaa cttcagtgta cagaacttaa ctaggtatgt gatttgagtg gcaaatacct
4861 gtaatccagc ctactcagga ggagactgag gcaggagaat tacaatgagt tcaaggccag
4921 tgtgggcttc ttgatcagtt ttaggctagt ataggttcca tacctgttga aagagagaaa
4981 ggaaggaagg aaggaaggaa ggaaggaagg aaggaaggaa agaaggaagg gggagggatg
5041 tagagggagg aagggaagga agaaaggaaa gaaggaagaa aggaaaggaa ggggaaatta
5101 actaggaagt ttcctcatgc tctaaggttc cagtctgata gataacaagg ataccccaaa
5161 tgatttatgg gaatcgtcta atgacctcct tgaaaaagtc cactctaaat tgtaggtagg
5221 agatccctcc aaaccaggac atactgaata tgagaacacc atctgtattt gtattgtcaa
5281 ctttcagtca gaaaaatgag cataggctga gcgtgcagtg agctcccgtg ctgctgggct
5341 agttggaagg gaagggagag agacatgtct tccttctttc aatagctcac tggtagtgta
5401 tgtgatgtgg aaggccctca ccaaaaaaag ggggggaact aaacgaatat taaaaccacc
5461 gctatcttgg accatggaga tggttcatta ggtaaggggt gtgctgccac acctaacacc
5521 caaaactcaa tccccaggcc ccacttacga gaaggcgaga agtgaccttt acaagttgtc
5581 ctctgtcctc cgcatgtgca cacaagtaaa taaataagaa ataagttaaa aattaaaaaa
5641 caatcacaat ccactatctt ttttattctt ctcttatata ttatatccca actgcagttc
5701 cccctccctc tccttccctg tctttccccc tacctcccct cttccacaga ttcccctccc
5761 ccaaaatcta ctatttttaa agttgatcat tttagataga atttttttta aatcattagt
5821 atggctggag gtgcagctct ttggtagagt gcccacctac catgcccaag accctgggtt
5881 ccatccgaag caccgggtgt ggtaccatat gcttgaaata ccagcacttg ggggggtaga
5941 ggcagaaggg tcagagtttc atacaagatg agcctggggt tacgaatggc attcaaggcc
6001 aactttcagt gcatgagacc cagtctcaaa actaacacaa aaggaacaca aaggaaagga
6061 aataaacaga aaagttggta ctttccccac agagcccaca agctcaggtc ccatctgttc
6121 ctcctgcagg aagcagtgga aagacccctt tgtgttccgc ccagagcggt ttcttaccaa
6181 taacaactcg gccatcgaca agacccagag cgagaaggtg atgctcttcg gcttgggaaa
6241 gcgccggtgc attggggaga tcccggccaa gtgggaagtc ttcctcttct tagccatcct
6301 gctgcagcat ctggagttta gtgtgccacc gggtgtgaag gtggacctga cacccaacta
6361 tgggttgacc atgaagcccg ggacctgtga acacgtccag gcatggccac gcttttccaa
6421 gtgaagattg tcgaggcatc ggtggggccg tcacccttgt ttcttttcct tttttaaaaa
6481 aaaaaaaaaa acagcttttt tttttttgag agatacaatt ctttccccat ttaattcatc
6541 tccaagcaat tttacaatag tgtctatcat gttcacccca taacccatac tcattaggac
6601 ttatgattta agattcctcc taccctgtct tgcttgccgc acctcatgct aatctagttt
6661 ttgactcaat agatttgcct actctggctg tctcatataa atcgaatgaa ttatg
//