GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSDHF5 670 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene fragment encoding dihydrofolate reductase (EC 1.5.1.3)
first exon. Five fragments of this gene are given in the entries
<MMDHF5>, <MMDHF6>, <MMDHF7>, <MMDHF8> and <MMDHF9>.
ACCESSION V00735
KEYWORDS dihydrofolate reductase; reductase.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 670)
AUTHORS Crouse,G.F., Simonsen,C.C., McEwan,R.N. and Schimke,R.T.
TITLE Structure of amplified normal and variant dihydrofolate reductase
genes in mouse sarcoma S180 cells
JOURNAL J. Biol. Chem. 257, 7887-7897 (1982)
STANDARD full automatic
COMMENT EPD; 07057; Mm DHFR P2+. EPD; 24032; Mm DHFR P1.
From EMBL entry MMDHF5; dated 13-JUL-1983.
FEATURES Location/Qualifiers
precursor_RNA 361..>670
/note="primary transcript"
mRNA 361..528
/note="exon 1"
CDS 443..528
/note="DHFR part 1 (528 is 2nd base in codon)"
/codon_start=443
BASE COUNT 125 a 189 c 238 g 118 t
ORIGIN
1 agacctgaag aaccggccta gaaccgtttg cctccccggg cttgggggcg gagtagagcc
61 tcccgacgcg gatttcccgg cgggcattgc agtgtgcaga agagccggcc tgctaggagc
121 gcgaggcgcg gccgcacttt ctcgcgcctg ccggcgcacg cctcaacctg tgcgggaccg
181 gccttggggg cggagcctta gctacacaaa tagaatgcgc ggcgggcctt ggtgggggcg
241 gggccttagc tgcacaaata ggatgcgcgg cgggccttgg taggggcgga gccttagctg
301 cacaaatagg atgcgcggcg ggccttggtg ggggcggggc ctaagctgcg caagtggtac
361 acagctcagg gctgcgattt cgcgccaaac ttgacggcaa tcctagcgtg aaggctggta
421 ggattttatc cccgctgcca tcatggttcg accattgaac tgcatcgtcg ccgtgtccca
481 aaatatgggg attggcaaga acggagacct accctggcct ccgctcaggt attggccggg
541 ctgggctggg aaactgaggc ggttcactga gtagggtcat gcacttggct tggacgcgcg
601 ggacgggcgt gaaagcagag cctaccggcc tcagccagag accaagctaa ccggttccac
661 gacggtgatc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSDHF6 383 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene fragment encoding dihydrofolate reductase (EC 1.5.1.3)
second exon. Five fragments of this gene are given in the entries
<MMDHF5>, <MMDHF6>, <MMDHF7>, <MMDHF8> and <MMDHF9>.
ACCESSION V00736
KEYWORDS dihydrofolate reductase; reductase.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 383)
AUTHORS Crouse,G.F., Simonsen,C.C., McEwan,R.N. and Schimke,R.T.
TITLE Structure of amplified normal and variant dihydrofolate reductase
genes in mouse sarcoma S180 cells
JOURNAL J. Biol. Chem. 257, 7887-7897 (1982)
STANDARD full automatic
COMMENT From EMBL entry MMDHF6; dated 13-JUL-1983.
FEATURES Location/Qualifiers
mRNA 71..120
/note="exon 2"
CDS 71..120
/note="DHFR part 2 (71 is 3rd base in codon) (120 is 1st
base in codon)"
/codon_start=71
BASE COUNT 110 a 68 c 85 g 120 t
ORIGIN
1 cggacttgca cctttcgtcg ctgaatggag cctgagcata catgacggtt aactgttctc
61 taattttcag gaacgagttc aagtacttcc aaagaatgac cacaacctct tcagtggaag
121 gtaatgtaga gtaattaagt catgagaatt atgtttgctt gaagcaagat ttacatggta
181 gaggtatgag tagaaagtct ccccttggga atcttgggat ctctgtttct tgctagaaat
241 ttttgtgacg attcccagat tttattaaac atcctcttag aatactctat gtttgaaatt
301 ttgttagcaa gtgcatatag ctcgaattat aactgggcag aatcggcagc aaaatttacg
361 actttgggta gagacctgag ccg
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSDHF7 458 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene fragment encoding dihydrofolate reductase (EC 1.5.1.3)
third exon. Five fragments of this gene are given in the entries
<MMDHF5>, <MMDHF6>, <MMDHF7>, <MMDHF8> and <MMDHF9>.
ACCESSION V00737
KEYWORDS dihydrofolate reductase; reductase.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 458)
AUTHORS Crouse,G.F., Simonsen,C.C., McEwan,R.N. and Schimke,R.T.
TITLE Structure of amplified normal and variant dihydrofolate reductase
genes in mouse sarcoma S180 cells
JOURNAL J. Biol. Chem. 257, 7887-7897 (1982)
STANDARD full automatic
COMMENT From EMBL entry MMDHF7; dated 13-JUL-1983.
FEATURES Location/Qualifiers
mRNA 335..440
/note="exon 3"
CDS 335..440
/note="DHFR part 3 (335 is 2nd base in codon) (440 is 2nd
base in codon)"
/codon_start=335
BASE COUNT 158 a 73 c 82 g 145 t
ORIGIN
1 aattcaggat tagaacctgt tctccacttt agacactaat aaagcatgta aggatatcaa
61 gtgaattaca aaatccagtc aacctgagcc ctgtggactg aaattatgca tggttcaatg
121 gattaaaacc taagtaaaat gatatgaact gcatgagcca aactgaaaaa ttgaactata
181 tttagagaac taaatctgaa ttttaggtaa agctgtttgt cttaattttt ctaaaggatg
241 cccactagat gtcactatga caatcgtctt gcctatgtat gtcactgaca atatatgtgt
301 attttctaat aatcttttct acttggtatt ataggtaaac agaatctggt gattatgggt
361 aggaaaacct ggttctccat tcctgagaag aatcgacctt taaaggacag aattaatata
421 gttctcagta gagaactcaa gttagtgtta taacatcg
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSDHF8 303 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene fragment encoding dihydrofolate reductase (EC 1.5.1.3)
fourth exon. Five fragments of this gene are given in the entries
<MMDHF5>, <MMDHF6>, <MMDHF7>, <MMDHF8> and <MMDHF9>.
ACCESSION V00738
KEYWORDS dihydrofolate reductase; reductase.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 303)
AUTHORS Crouse,G.F., Simonsen,C.C., McEwan,R.N. and Schimke,R.T.
TITLE Structure of amplified normal and variant dihydrofolate reductase
genes in mouse sarcoma S180 cells
JOURNAL J. Biol. Chem. 257, 7887-7897 (1982)
STANDARD full automatic
COMMENT From EMBL entry MMDHF8; dated 13-JUL-1983.
FEATURES Location/Qualifiers
mRNA 90..217
/note="exon 4"
CDS 90..217
/note="DHFR part 4 (90 is 3rd base in codon)"
/codon_start=90
BASE COUNT 88 a 59 c 64 g 92 t
ORIGIN
1 gtttgtacta gctgctgcca attcggatta tttgactagt gtggacagac ttttacaaaa
61 accataagtc tttttttttt tgaacctcag agaaccacca cgaggagctc attttcttgc
121 caaaagtttg gatgatgcct taagacttat tgaacaaccg gaattggcaa gtaaagtaga
181 catggtttgg atagtcggag gcagttctgt ttaccaggta agtagagttg tgtataaaga
241 attacccttc tctacttgcc accatgcaca tggaaacagg acattgtccg ctgtaaacta
301 cac
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSDHF9 389 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene fragment encoding dihydrofolate reductase (EC 1.5.1.3)
fifth exon. Five fragments of this gene are given in the entries
<MMDHF5>, <MMDHF6>, <MMDHF7>, <MMDHF8> and <MMDHF9>.
ACCESSION V00739
KEYWORDS dihydrofolate reductase; reductase.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 389)
AUTHORS Crouse,G.F., Simonsen,C.C., McEwan,R.N. and Schimke,R.T.
TITLE Structure of amplified normal and variant dihydrofolate reductase
genes in mouse sarcoma S180 cells
JOURNAL J. Biol. Chem. 257, 7887-7897 (1982)
STANDARD full automatic
COMMENT From EMBL entry MMDHF9; dated 13-JUL-1983.
FEATURES Location/Qualifiers
mRNA 228..343
/note="exon 5"
CDS 228..343
/note="DHFR part 5 (343 is 2nd base in codon)"
/codon_start=228
BASE COUNT 138 a 71 c 64 g 116 t
ORIGIN
1 ccggcctcca caaatatcag tactcacaaa aacattatta acattattag gcatcatttt
61 aaaaatataa gcaaatcttt ttttcaaaat attttatacg tagtaagact gaacagctgt
121 aaacacgcat ttaatgccta gtacaaactt aactaaaaca agtaccttcc agtctctgcc
181 tttcagcaca ggttgaggag agtgatacct tgtgttttgt tttaaaggaa gccatgaatc
241 aaccaggcca ccttagactc tttgtgacaa ggatcatgca ggaatttgaa agtgacacgt
301 ttttcccaga aattgatttg gggaaatata aacttctccc agagtaagat acaattatta
361 attagagaga agtactttaa ggacttaag
//